A convenient, one-step, high-yield replacement of an anomeric hydroxyl group by a fluorine atom using dast. Preparation of glycosyl fluorides.

A simple and practical method for the synthesis on a large scale of altretamine (1), a wellknown antitumor drug, has been successfully developed. The synthesis method involves the conversion of cyanuric chloride (2) into altretamine (1) by dimethylamination of 2 with an aqueous solution of 40% dimethylamine and potassium hydroxide in 1, -dioxan 4in one step to give altretamine (1) in high yield.

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Constructing Large 2D Lattices Out of DNA-Tiles

Molecules ◽

10.3390/molecules26061502 ◽

2021 ◽

Vol 26 (6) ◽

pp. 1502

Author(s):

Johannes M. Parikka ◽

Karolina Sokołowska ◽

Nemanja Markešević ◽

J. Jussi Toppari

Keyword(s):

Self Assembly ◽

Dna Nanotechnology ◽

Building Blocks ◽

High Yield ◽

Dna Nanostructures ◽

Liquid Interfaces ◽

Basic Principles ◽

Dna Tiles ◽

One Step ◽

Solid Liquid

The predictable nature of deoxyribonucleic acid (DNA) interactions enables assembly of DNA into almost any arbitrary shape with programmable features of nanometer precision. The recent progress of DNA nanotechnology has allowed production of an even wider gamut of possible shapes with high-yield and error-free assembly processes. Most of these structures are, however, limited in size to a nanometer scale. To overcome this limitation, a plethora of studies has been carried out to form larger structures using DNA assemblies as building blocks or tiles. Therefore, DNA tiles have become one of the most widely used building blocks for engineering large, intricate structures with nanometer precision. To create even larger assemblies with highly organized patterns, scientists have developed a variety of structural design principles and assembly methods. This review first summarizes currently available DNA tile toolboxes and the basic principles of lattice formation and hierarchical self-assembly using DNA tiles. Special emphasis is given to the forces involved in the assembly process in liquid-liquid and at solid-liquid interfaces, and how to master them to reach the optimum balance between the involved interactions for successful self-assembly. In addition, we focus on the recent approaches that have shown great potential for the controlled immobilization and positioning of DNA nanostructures on different surfaces. The ability to position DNA objects in a controllable manner on technologically relevant surfaces is one step forward towards the integration of DNA-based materials into nanoelectronic and sensor devices.

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Fast one-step synthesis of N-doped carbon dots by pyrolyzing ethanolamine

Journal of Materials Chemistry C ◽

10.1039/c4tc01139b ◽

2014 ◽

Vol 2 (36) ◽

pp. 7477-7481 ◽

Cited By ~ 99

Author(s):

Xinwei Dong ◽

Yanjie Su ◽

Huijuan Geng ◽

Zhongli Li ◽

Chao Yang ◽

...

Keyword(s):

Hydrogen Peroxide ◽

Carbon Dots ◽

High Yield ◽

One Step ◽

Doped Carbon Dots

N-doped CDs can be obtained directly with high yield by pyrolyzing ethanolamine in air within just 7 minutes with the assistance of hydrogen peroxide.

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The Effect of Operational Parameters on the Photocatalytic Mineralization of Indocorn Brilliant Red M5B Using Sol–gel Derived Nanostructured Zinc Titanate as an Efficient Photocatalyst

Journal of Advanced Oxidation Technologies ◽

10.1515/jaots-2012-0214 ◽

2012 ◽

Vol 15 (2) ◽

Author(s):

Mohammad Hossein Habibi ◽

Maryam Mikhak

Keyword(s):

Azo Dye ◽

Sol Gel ◽

Degradation Efficiency ◽

High Yield ◽

Operational Parameters ◽

Solution Ph ◽

Zinc Titanate ◽

First Order Kinetics ◽

Size Uniformity ◽

One Step

AbstractNanostructured zinc titanate (NZT) was synthesized in high yield via a one-step and template-free sol-gel route. The prepared nanocomposite exhibited good size uniformity and regularity. The enhanced photocatalytic activity of the NZT was evaluated in the degradation and mineralization of Indocorn Brilliant Red (M5B) under metal halide lamp irradiation. The effects of different parameters such as pH of the solution, and initial dye concentration on photodegradation of M5B were analyzed. The degradation of M5B follows pseudo-first order kinetics according to the Langmuir-Hinshelwood model. The experimental results showed that the initial concentration of azo dye in the dye mixture greatly affected the degradation efficiency. At M5B concentrations of 10 mg/L, the optimum conditions for the highest degradation efficiency (94%) of azo dye were a photocatalyst dosage of 0.01 g/L and an initial solution pH of 9. This study provided new insight into the design and preparation of nanomaterial demonstrated an excellent ability to remove organic pollutants in wastewater.

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ChemInform Abstract: SYNTHESIS OF CYCLOPENTA(C,D)PYRENE VIA A HIGH YIELD ONE-STEP PREPARATION OF PYREN-4-YLACETIC ACID FROM PYRENE

Chemischer Informationsdienst ◽

10.1002/chin.198225140 ◽

1982 ◽

Vol 13 (25) ◽

Author(s):

K. TINTEL ◽

J. LUGTENBURG ◽

J. CORNELISSE

Keyword(s):

High Yield ◽

One Step ◽

Ylacetic Acid

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Complexation of Cu(BF4)2 with 3-hydroxyflavone in acetonitrile: quantum chemical calculation

Kharkov University Bulletin Chemical Series ◽

10.26565/2220-637x-2018-31-05 ◽

2018 ◽

Keyword(s):

Hydrogen Bond ◽

Hydrogen Atom ◽

Intramolecular Hydrogen Bond ◽

Quantum Chemical ◽

Phenyl Ring ◽

Fluorine Atom ◽

Quantum Chemical Study ◽

Hydroxyl Group ◽

Chemical Calculation ◽

Intramolecular Hydrogen

In the article the results of the quantum chemical study of copper (II) solvato-complexes with acetonitrile (AN), tetrafluoroborate anion (BF4–) and 3-hydroxyflavone (flv) of the composition [Cu(AN)6]2+, [Cu(BF4)(AN)5]+, [Cu(flv)(AN)5]2+, [Cu(flv)(BF4)(AN)4]+ are presented. Calculations were done using density function theory (DFT) on the M06-2X/6-311++G(d,p) level of theory. Obtained results were interpreted in terms of complexes geometry and topology of electron density distribution using non-covalent interactions (NCI) approach. It was shown that flv molecule is a monodentate ligand in copper (II) complexes and coordinates central atom via carbonyl oxygen. Intramolecular hydrogen bond that exists in an isolated flv molecule was found to be broken upon [Cu(flv)(AN)5]2+ complex formation. In [Cu(flv)(AN)5]2+ complex, a significant rotation of phenyl ring over the planar chromone fragment was spotted as a consequence of intramolecular hydrogen bond breaking. Upon inclusion of BF4– anion to the first solvation shell of Cu2+, an intracomplex hydrogen bond was formed between hydrogen atom of hydroxyl group of flv molecule and the closest fluorine atom of BF4– anion. NCI analysis had shown that a hydrogen bond between hydrogen atom of hydroxyl group of flv molecule and the closest fluorine atom of BF4– anion is significantly stronger than intramolecular hydrogen bond in an isolated flv molecule. In addition, flexible phenyl ring of flv molecule in [Cu(flv)(BF4)(AN)4]+ complex was found to be internally stabilized by the weak van der Waals attraction between oxygen atoms of chromone ring and phenyl hydrogens. These evidences led to a conclusion that [Cu(flv)(BF4)(AN)4]+ complex is more stable, comparing to the in [Cu(flv)(AN)5]2+ complex.

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A Single-Step Synthesis of Azetidine-3-Amines

10.26434/chemrxiv.12846629.v1 ◽

2020 ◽

Author(s):

Brian J Wang ◽

Matthew Duncton

Keyword(s):

Functional Groups ◽

Late Stage ◽

Single Step ◽

Secondary Amines ◽

High Yield ◽

Primary Amines ◽

Privileged Structure ◽

One Step ◽

Alternative Procedures ◽

Approved Drugs

<div> <p>The azetidine group is frequently encountered within contemporary medicinal chemistry where it is viewed as a privileged structure. However, the introduction of an azetidine can be synthetically challenging. Herein, a straight-forward one step synthesis of azetidine-3-amines, starting from a bench stable, commercial material is presented. The reaction tolerates functional groups commonly encountered in biological-, medicinal- and agro-chemistry, and proceeds in moderate-to-high yield with secondary amines, and moderate-to-low yield with primary amines. The methodology compares favorably to recent alternative procedures and can be utilized in “any-stage” functionalization, including late-stage azetidinylation of approved drugs and other compounds with pharmacological activity.</p> </div>

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One-step catalytic amination of naphthalene to naphthylamine with exceptional yield

Green Chemistry ◽

10.1039/d0gc00633e ◽

2020 ◽

Vol 22 (9) ◽

pp. 2744-2749

Author(s):

Fang Hao ◽

Xin Wang ◽

Linfang Huang ◽

Wei Xiong ◽

Pingle Liu ◽

...

Keyword(s):

Mild Condition ◽

Major Product ◽

High Yield ◽

Vanadium Catalysts ◽

Catalytic Amination ◽

One Step ◽

First Time

This is the first time to synthesize naphthylamine from one-step naphthalene amination by vanadium catalysts with high yield under mild condition. It could obtain ∼70% yield of naphthylamine, with major product of valuable 1,5-diaminonaphthalene.

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