Pandemic H1N1 infection in pregnant women in the USA

The Lancet ◽  
2009 ◽  
Vol 374 (9688) ◽  
pp. 429-430 ◽  
Author(s):  
Punam Mangtani ◽  
Tippi K Mak ◽  
Dina Pfeifer
2012 ◽  
Vol 140 (12) ◽  
pp. 2210-2222 ◽  
Author(s):  
H. BURKOM ◽  
K. KNISS ◽  
M. MELTZER ◽  
L. BRAMMER ◽  
Y. ELBERT ◽  
...  

SUMMARYA pandemic H1N1 infection wave in the USA occurred during spring 2009. Some hypothesized that for regions affected by the spring wave, an autumn outbreak would be less likely or delayed compared to unaffected regions because of herd immunity. We investigated this hypothesis using the Outpatient Influenza-like Illness (ILI) Network, a collaboration among the Centers for Disease Control and Prevention, health departments, and care providers. We evaluated the likelihood of high early autumn incidence given high spring incidence in core-based statistical areas (CBSAs). Using a surrogate incidence measure based on influenza-related illness ratios, we calculated the odds of high early autumn incidence given high spring incidence. CBSAs with high spring ILI ratios proved more likely than unaffected CBSAs to have high early autumn ratios, suggesting that elevated spring illness did not protect against early autumn increases. These novel methods are applicable to planning and studies involving other infectious diseases.


BMJ Open ◽  
2012 ◽  
Vol 2 (4) ◽  
pp. e000827 ◽  
Author(s):  
Furong Li ◽  
Guoping Chen ◽  
Jianjun Wang ◽  
Hong Liu ◽  
Jiabing Wu

2013 ◽  
Vol 191 (5) ◽  
pp. 2474-2485 ◽  
Author(s):  
J. Justin Milner ◽  
Patricia A. Sheridan ◽  
Erik A. Karlsson ◽  
Stacey Schultz-Cherry ◽  
Qing Shi ◽  
...  

2013 ◽  
Vol 16 (8) ◽  
pp. 1390-1402 ◽  
Author(s):  
Carin Andrén Aronsson ◽  
Kendra Vehik ◽  
Jimin Yang ◽  
Ulla Uusitalo ◽  
Kristen Hay ◽  
...  

AbstractObjectivesThe aim of the present study was to examine the prevalence and associated factors of dietary supplement use, particularly supplements containing vitamin D and fatty acids, in pregnant women enrolled in a multi-national study.DesignThe Environmental Determinants of Diabetes in the Young (TEDDY) study is a prospective longitudinal cohort study. Maternal dietary supplement use was self-reported through questionnaires at month 3 to 4 postpartum.SettingSix clinical research centres; three in the USA (Colorado, Georgia/Florida and Washington) and three in Europe (Sweden, Finland and Germany).SubjectsMothers (n 7326) to infants screened for high-risk HLA-DQ genotypes of type 1 diabetes.ResultsNinety-two per cent of the 7326 women used one or more types of supplement during pregnancy. Vitamin D supplements were taken by 65 % of the women, with the highest proportion of users in the USA (80·5 %). Overall, 16 % of the women reported taking fatty acid supplements and a growing trend was seen in all countries between 2004 and 2010 (P < 0·0001). The use was more common in Germany (32 %) and the USA (24 %) compared with Finland (8·5 %) and Sweden (7·0 %). Being pregnant with the first child was a strong predictor for any supplement use in all countries. Low maternal age (<25 years), higher education, BMI ≥ 25·0 kg/m2 and smoking during pregnancy were factors associated with supplement use in some but not all countries.ConclusionsThe majority of the women used dietary supplements during pregnancy. The use was associated with sociodemographic and behavioural factors, such as parity, maternal age, education, BMI and maternal smoking.


2015 ◽  
Vol 70 (6) ◽  
pp. 621-626
Author(s):  
Mikhail Timofeevich Lutsenko ◽  
Irina Anatol'evna Andrievskaya

Aim: to study the process of proteins transamination in syncytiotrophoblast of placenta villi of women who suffered the acute form of cytomegalovirus (CMV) infection during pregnancy.Methods: 30 pregnant women with CMV infection recurrence at the 25–28th week of pregnancy were examined. The activity of γ-glutamyltransferase in the peripheral blood of pregnant women was determined by spectrophotometry at the device «Stat-Fax-2100» (The USA). Hsp-70 and caspase-3 in placenta homogenate were found out with serological methods. The activity of glutamatdehydrogenase and pyridoxal-5-phosphatase was studied with histochemical method of Z. Loyd at the placenta slice of parturient women. The apoptotic changes in syncytiotrophoblast nuclei were defined by ISEL-method.Results. The peripheral blood of CMV-seropositive parturient women showed a reduction of γ-glutamyltransferase in 1.30 times. Histochemically we identified the reduction of reaction products' concentration in response to pyridoxal-5-phosphate by 2.14 times, to glutamatdehydrogenase by 1,57 times. At the same time there was an increase of caspase-3 in 2,8 times and reduction of Hsp70 in 2.6 times in placenta homogenate. The number of apoptotic changes in syncytiotrophoblast nuclei increased by 4 times.Conclusion. Worsening of CMV infection in the period 25–28 weeks of pregnancy leads to disruption of amino acid metabolism in the placenta, causing structural and functional and metabolic adjustment, and is one of the reasons for slow growth and lack of development of the fetus. 


2018 ◽  
Vol 31 (6) ◽  
pp. 470-471
Author(s):  
Sean Roberts ◽  
Dennis W. Metzger ◽  
Steven M. Szczepanek

Author(s):  
Taghreed N. Salameh ◽  
Lynne A. Hall ◽  
Timothy N. Crawford ◽  
Ruth R. Staten ◽  
Martin T. Hall

Author(s):  
Alexandra Fanghanel

This chapter examines what happens when the pregnant body in public space is perceived to be troublesome, or, because of its ambiguous position, disruptive. This chapter focuses on the pregnant body in public space as a sexualized body. Running through this chapter are snippets of sex advice given to pregnant women in specialist magazines. The first part examines representation of sexualised pregnant bodies in mainstream discourses; notably ‘sexy’ pregnancy photoshoots and advertising. The concept of herethical sexual ethics is analysed in dialogue with these representations of motherhood-to-come (Kristeva, 1985). The second part of the chapter draws on data from women in the USA and UK to examine sexual harassment of pregnant women. Sexual harassment is a mode of gender exclusion, in any case. When women who are pregnant experience sexual harassment in pregnancy, it becomes a further technique of control, fuelled by rape culture, which codes public spaces as places in which pregnant women do not belongThis chapter establishes how norms of pregnancy uphold heteropatriarchal performances of, and interactions with, gender and sexuality in public space. It argues that mobilising becoming-minoritarian politics established by Deleuze and Guattari and the herethical approaches of Kristeva, we start to set the scene for a guerrilla war machine to emerge.


PLoS ONE ◽  
2011 ◽  
Vol 6 (5) ◽  
pp. e19872 ◽  
Author(s):  
Miriam Lichtner ◽  
Claudio M. Mastroianni ◽  
Raffaella Rossi ◽  
Gianluca Russo ◽  
Valeria Belvisi ◽  
...  

Author(s):  
Priscila Dobbler ◽  
Volker Mai ◽  
Renato S. Procianoy ◽  
Rita C. Silveira ◽  
Andréa L. Corso ◽  
...  

Abstract The female lower genital tract harbors a complex microbial community essential for homeostasis and health. During pregnancy, the female body undergoes unique hormonal changes that contribute to weight gain as well as modulations in immune function that can affect microbiota composition. Several studies have described the vaginal microbiota of pregnant women from the USA, Europe and Mexico. Here we expand our knowledge about the vaginal microbial communities during the third trimester to healthy expectant Brazilian mothers. Vaginal samples were collected from patients delivering at the Hospital de Clínicas de Porto Alegre, Brazil. Microbial DNA was isolated from samples and the V4 region of the 16S rRNA gene was amplified and sequenced using the PGM Ion Torrent. Brazilian pregnant women presented three distinct types of microbial community at the time of labor. Two microbial communities, Cluster 1 and Cluster 3, presented an overall dominance of Lactobacillus while Cluster 2 tended to present higher diversity and richness, with the presence of Pseudomonas, Prevotella and other vaginosis related bacteria. About half of the Brazilian mothers sampled here had dominance of L. iners. The proportion of mothers without dominance of any Lactobacillus was higher in Brazil (22%) compared to UK (2.4%) and USA, where this community type was not detected. The vaginal microbiota showed significant correlation with the composition of the babies’ gut microbiota (p-value = 0.002 with a R2 of 15.8%). Mothers presenting different vaginal microbiota shared different microorganisms with their newborns, which would reflect on initial colonizers of the developing newborns’ gut.


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