scholarly journals The acute effect of tea consumption with a high fat meal on flow-mediated brachial artery vasodilation in healthy individuals

2002 ◽  
Vol 39 ◽  
pp. 218
Author(s):  
Mary C. Corretti ◽  
Yeymi W. DeLeon ◽  
Charles Mangano ◽  
Robert A. Vogel ◽  
Gary D. Plotnick
Keyword(s):  
Brachial Artery ◽  
Acute Effect ◽  
Tea Consumption ◽  
Healthy Individuals ◽  
High Fat ◽  
Fat Meal

scholarly journals The effect of 13 weeks of running training followed by 9 d of detraining on postprandial lipaemia

1998 ◽  
Vol 80 (1) ◽  
pp. 57-66 ◽  
Author(s):  
Sara L. Herd ◽  
Adrianne E. Hardman ◽  
Leslie H. Boobis ◽  
Caroline J. Cairns
Keyword(s):  
Young Adults ◽  
Training Session ◽  
Acute Effect ◽  
Single Session ◽  
High Fat ◽  
Postprandial Lipaemia ◽  
Blood Samples ◽  
Running Training ◽  
Short Period ◽  
Fat Meal

The present study examined the influence of training, followed by a short period of detraining, on postprandial lipaemia. Fourteen normolipidaemic, recreationally active young adults aged 18–31 years participated, in two self-selected groups: three men and five women (BMI 21·7–27·6 kg/m2) completed 13 weeks of running training, after which they refrained from exercise for 9 d; three men and three women (BMI 21·5–25·6 kg/m2) maintained their usual lifestyle. Oral fat tolerance tests were conducted at baseline and again 15 h, 60 h and 9 d after the runners' last training session. Blood samples were drawn after an overnight fast and at intervals for 6 h after consumption of a high-fat meal (1·2 g fat, 1·4 g carbohydrate, 70·6 kJ energy/kg body mass). Heparin was then administered (100 IU/kg) and a further blood sample was drawn for measurement of plasma lipoprotein lipase (EC3.1.1.34; LPL) activity. Endurance fitness improved in runners, relative to controls (maximal O2uptake +3·2 (SE 1·1) ml/kg per minv.− 1·3 (SE 1·2) ml/kg per min; P < 0·05). In the absence of the acute effect of exercise, i.e. 60 h after the last training session, there was no effect of training on either postprandial lipaemia or on post-heparin LPL activity. However, changes during 9 d of detraining in both these variables differed significantly between groups; after 2 d without exercise (60 h test), the runners' lipaemic response was 37% higher than it was the morning after their last training session (15 h test; runnersv.controlsP< 0·05), with a reciprocal decrease in post-heparin LPL activity (P< 0·01). These findings suggest that improved fitness does not necessarily confer an effect on postprandial lipaemia above that attributable to a single session of exercise.

scholarly journals Acute Effect of High-Fat Meal on Endothelial Function in Moderately Dyslipidemic Subjects

2005 ◽  
Vol 25 (2) ◽  
pp. 406-410 ◽  
Author(s):  
C. Giannattasio ◽  
A. Zoppo ◽  
G. Gentile ◽  
M. Failla ◽  
A. Capra ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Acute Effect ◽  
High Fat ◽  
Fat Meal

A comparison between active- and reactive-hyperaemia-induced brachial artery vasodilation

2006 ◽  
Vol 110 (3) ◽  
pp. 387-392 ◽  
Author(s):  
Jaume Padilla ◽  
Ryan A. Harris ◽  
Alyce D. Fly ◽  
Lawrence D. Rink ◽  
Janet P. Wallace
Keyword(s):  
Endothelial Function ◽  
Brachial Artery ◽  
Repeated Measures ◽  
Reactive Hyperaemia ◽  
High Fat ◽  
Low Fat ◽  
Balanced Design ◽  
Treatment Conditions ◽  
Main Effects ◽  
Fat Meal

The measurement of brachial artery vasodilation in response to a hyperaemic stimulus has been used extensively to assess changes in endothelial function. However, whether or not similar changes occur in response to an active hyperaemic stimulus is unknown. The purpose of the present study was to compare brachial artery vasodilation in response to an active compared with a reactive hyperaemic stimulus following a known perturbation of endothelial function. Eight apparently healthy adults were assigned to four treatment conditions in a counter-balanced design: (i) low-fat meal with active hyperaemic stimulus (LFM-A), (ii) high-fat meal with active hyperaemic stimulus (HFM-A), (iii) low-fat meal with reactive hyperaemic stimulus (LFM-R), and (iv) high-fat meal with reactive hyperaemic stimulus (HFM-R). Meals were ingested at 08:00 hours on each treatment day. Brachial artery vasodilation was assessed via ultrasound 4 h after ingestion of each meal. The active hyperaemic stimulus was induced by 5 min of rhythmic handgrip exercise, whereas reactive hyperaemia was induced by 5 min of forearm occlusion. Brachial artery vasodilation was expressed as the percentage change in diameter from baseline to post-active/reactive hyperaemia. Using a 2×2 repeated measures ANOVA, a significant stimulus×meal interaction (P=0.025) was found. Simple main effects revealed no difference (P=0.541) in brachial artery vasodilation between LFM-A (5.75±1.64%) and HFM-A (6.39±1.45%); however, a significant decrease (P=0.014) in brachial artery vasodilation was found in the HFM-R (4.29±1.64%) compared with the LFM-R (7.18±1.13%) treatment. In conclusion, the measurement of brachial artery vasodilation in response to active hyperaemia did not detect a change in endothelial function following a single perturbation meal, whereas reactive hyperaemia did.

The effect of acute fish-oil supplementation on endothelial function and arterial stiffness following a high-fat meal

2010 ◽  
Vol 35 (3) ◽  
pp. 294-302 ◽  
Author(s):  
Christopher A. Fahs ◽  
Huimin Yan ◽  
Sushant Ranadive ◽  
Lindy M. Rossow ◽  
Stamatis Agiovlasitis ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Endothelial Function ◽  
Fish Oil ◽  
Brachial Artery ◽  
Omega 3 ◽  
High Fat ◽  
Time Interaction ◽  
Artery Stiffness ◽  
Fish Oil Supplementation ◽  
Fat Meal

This study examined whether a commercially available fish-oil supplement offers protection from the acute effects of a high-fat meal (HFM) on endothelial function and arterial stiffness. An HFM causes acute impairments in endothelial function, whereas the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have a variety of cardioprotective effects. However, little is known about the efficacy of moderate fish-oil supplementation on the endothelial dysfunction induced by an HFM. Endothelial function (brachial artery flow-mediated dilation (FMD)), forearm blood flow (FBF), total hyperemia, central and peripheral blood pressure, and central artery stiffness were assessed in 20 healthy men (n = 10) and women (n = 10) at rest and 4 h after an HFM supplemented with either placebo or ∼1 g EPA and DHA. Brachial artery FMD normalized for shear rate was significantly impaired (p = 0.033) following the HFM with placebo but remained unchanged compared with baseline following the HFM with the fish-oil supplement (p = 0.039; condition × time interaction). Resting FBF (p = 0.020) and total hyperemia (p = 0.014) were elevated following the HFM. All other vascular and hemodynamic measurements were unchanged in both trials. Commercially available fish-oil supplements taken with an HFM appear to preserve endothelial function following an HFM.

scholarly journals Comparison of a Standardized High-Fat Meal versus a High-Fat Meal Scaled to Body Mass for Measuring Postprandial Triglycerides: A Randomized Crossover Study

Metabolites ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 81
Author(s):  
Bryant H. Keirns ◽  
Christina M. Sciarrillo ◽  
Samantha M. Hart ◽  
Sam R. Emerson
Keyword(s):  
Body Weight ◽  
Body Mass ◽  
Risk Classification ◽  
Healthy Individuals ◽  
High Fat ◽  
Cvd Risk ◽  
Equal Distribution ◽  
Postprandial Triglycerides ◽  
Postprandial Triglyceride ◽  
Fat Meal

Post-meal triglycerides are an independent cardiovascular disease (CVD) risk factor, but the ideal high-fat meal formulation has yet to be standardized and is one challenge prohibiting widespread clinical adoption of postprandial triglyceride assessment. Two general approaches often used are giving individuals a high-fat meal scaled to body weight or a standardized high-fat meal containing a set fat bolus. A recent expert panel statement has endorsed the latter, specifying 75 g of fat as an appropriate fat dosage. Despite this recommendation, no study to date has tested whether there is a difference in postprandial triglycerides or if risk classification is affected based on these different approaches. We recruited 16 generally healthy individuals with roughly equal distribution among body mass index (BMI)class (n = 5–6/per BMI category) and sex (n = 2–3 M/F) within each BMI class. Each participant underwent two abbreviated fat tolerance tests separated by ~1 week: one with a scaled to body weight high-fat meal (9 kcal/kg; 70% fat) and a standardized meal containing 75 g of fat (70% fat). Fasting, 4 h, and absolute change in triglycerides across the entire sample and within each BMI category were similar regardless of high-fat meal. Only one participant with obesity had discordant postprandial responses between the fat tolerance tests (i.e., different CVD risk classification). These findings suggest that, within a certain range of fat intake, generally healthy individuals will have a similar postprandial triglyceride response. Considering the greater convenience of utilizing standardized high-fat meals, our data suggest that a standardized high-fat meal may be acceptable for large-scale studies and clinical implementation.

The acute effect of green tea consumption on endothelial function in healthy individuals

2008 ◽  
Vol 15 (3) ◽  
pp. 300-305 ◽  
Author(s):  
Nikolaos Alexopoulos ◽  
Charalambos Vlachopoulos ◽  
Konstantinos Aznaouridis ◽  
Katerina Baou ◽  
Carmen Vasiliadou ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Green Tea ◽  
Acute Effect ◽  
Tea Consumption ◽  
Healthy Individuals

Effects of Acute Active Video Games on Endothelial Function Following a High-Fat Meal in Overweight Adolescents

2015 ◽  
Vol 12 (6) ◽  
pp. 869-874 ◽  
Author(s):  
Soo Hyun Park ◽  
Eun Sun Yoon ◽  
Yong Hee Lee ◽  
Chul-Ho Kim ◽  
Kanokwan Bunsawat ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Brachial Artery ◽  
Video Game ◽  
Vascular Function ◽  
Significant Interaction ◽  
High Fat ◽  
Active Video Game ◽  
Active Video ◽  
Overweight Adolescents ◽  
Fat Meal

Background:We tested the hypothesis that an active video game following a high-fat meal would partially prevent the unfavorable effect of a high-fat meal on vascular function in overweight adolescents.Methods:Twenty-four overweight adolescents were randomized to either a 60-minute active video game (AVG) group (n = 12) or seated rest (SR) as a control group (n = 12) after a high-fat meal. Blood parameters were measured, and vascular function was measured using brachial artery flow-mediated dilation (FMD) at baseline and 3 hours after a high-fat meal.Results:No significant interaction was found in any blood parameter. A high-fat meal significantly increased blood triglyceride and glucose concentrations in both groups in a similar manner. Brachial artery FMD significantly decreased in the SR group (13.8 ± 3.2% to 11.8 ± 2.5), but increased in the AVG group (11.4 ± 4.0% to 13.3 ± 3.5), with a significant interaction (P = .034).Conclusion:These findings show that an active video game attenuated high-fat meal-induced endothelial dysfunction. This suggests that an active video game may have a cardioprotective effect on endothelial function in overweight adolescents when exposed to a high-fat meal.

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