scholarly journals Human G-protein  3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure

2000 ◽  
Vol 13 (2) ◽  
pp. 140-145 ◽  
Author(s):  
K. Ishikawa ◽  
Y. Imai ◽  
T. Katsuya ◽  
T. Ohkubo ◽  
I. Tsuji ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
G Protein ◽  
Serum Potassium ◽  
Cholesterol Levels

scholarly journals THE STATE OF CHOLESTEROL LEVEL IN HYPERTENSION IN SADANANYA HEALTH CENTER

2021 ◽  
Vol 4 (2) ◽  
pp. 80-85
Author(s):  
Irpan Ali Rahman ◽  
Endrian Mulyadi Justitia Waluyo ◽  
Shafira Aisyah Darmawan
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
Health Center ◽  
Cholesterol Level ◽  
Blood Cholesterol ◽  
High Total Cholesterol ◽  
High Cholesterol ◽  
Hypertensive Patients ◽  
Cholesterol Levels ◽  
Quantitative Descriptive

Hypertension is an increase in systolic blood pressure above 140 mmHg and diastolic blood pressure above 90 mmHg. The number of hypertension sufferers has increased each year, in 2015 it reached 19,552, in 2016 it reached 24,750 and in 2017 it reached 38,057. In 2017 there were 115 hypertensive patients recorded in the report book that checked their health at the Sadananya Health Center. One of the causes of the high incidence of hypertension is cholesterol caused by the consumption of inappropriate food. One of the laboratory examinations to support hypertension diagnosis is blood cholesterol examination which can show excess cholesterol which makes hypertension difficult to control. To know the description of total cholesterol levels in hypertensive patients at the Sadananya Health Center. Quantitative descriptive, the population in this study were people with hypertension at the Sadananya Health Center. Sampling with accidental sampling, as many as 30 respondents. The cholesterol examination method used is CHOD-PAP. The results showed that blood pressure in respondents all had high blood pressure, namely >140/90 mmHg (100%), a high cholesterol level of 24 respondents (80%), blood pressure 140-150 who had high cholesterol as many 13 respondents, blood pressure 160-170 who had high cholesterol as much 6 respondents, blood pressure >180 who had high cholesterol as much 5 respondents. This study concludes that hypertensive clients have more high total cholesterol levels, which is as much as 80% and normal 20%. More hypertensive patients have high total cholesterol levels, which are 80% and 20% normal.

scholarly journals Combined Effect of Blood Pressure and Total Cholesterol Levels on Long-Term Risks of Subtypes of Cardiovascular Death

Hypertension ◽  
2015 ◽  
Vol 65 (3) ◽  
pp. 517-524 ◽  
Author(s):  
Michihiro Satoh ◽  
Takayoshi Ohkubo ◽  
Kei Asayama ◽  
Yoshitaka Murakami ◽  
Masaru Sakurai ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
Cardiovascular Death ◽  
Combined Effect ◽  
Cholesterol Levels

scholarly journals Effects of a social support family caregiver training program on changing blood pressure and lipid levels among elderly at risk of hypertension in a northern Thai community

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0259697
Author(s):  
Sorawit Boonyathee ◽  
Katekaew Seangpraw ◽  
Parichat Ong-Artborirak ◽  
Nisarat Auttama ◽  
Prakasit Tonchoy ◽  
...  
Keyword(s):  
Social Support ◽  
Blood Pressure ◽  
Total Cholesterol ◽  
Elderly People ◽  
Family Caregiver ◽  
Self Efficacy ◽  
The Elderly ◽  
Caregiver Training ◽  
Cholesterol Levels ◽  
Support Family

Hypertension is becoming increasingly prevalent among the elderly. Family caregivers play an important role in caring for elderly people and empowering them to care for themselves. This study’s goal was to see how social support training for family caregivers affected changes in hypertension, total cholesterol, and high-density lipoprotein (HDL), and how such support led to the prevention of hypertension behaviors among the elderly in rural areas. This was a quasi-experimental study with 268 elderly people at risk of hypertension and their caregivers. Sixty seven pairs of elderly people and their caregivers were assigned to the intervention and control groups. Baseline data were collected in November 2020. The intervention group received the Social Support Family Caregiver Training Program (SSFCTP), while the control group received a regular program from the local health authority. The activity lasted 12 weeks, with home visits and telephone check-ups along the way, and data collection took place after the program ended. The final data were collected three months after the end of the intervention. An analysis of repeated measures ANOVA showed the overall effect of the SSFCTP on knowledge, self-efficacy, health care behaviors, and blood pressure among elderly people during three different time periods (p<0.05). Furthermore, the intervention program had a time-dependent effect on knowledge, blood pressure, and total cholesterol levels (p<0.05). In terms of caregiver outcomes, there was an overall difference among the degrees of knowledge, self-efficacy, and behaviors toward health care displayed by elderly hypertensive patients during the three different time periods (p<0.05). The average knowledge and self-efficacy of the participants improved after the intervention. As a result, better self-care behaviors and lower blood pressure and total cholesterol levels were observed among the elderly participants after the intervention. The programs emphasized the importance of caregivers’ roles in providing social support, boosting confidence, and encouraging participation in caring, monitoring, and assisting the elderly in controlling blood pressure and other health issues.

scholarly journals Abdominal Fat Distribution and Cardiovascular Risk in Men and Women With Different Levels of Glucose Tolerance

2015 ◽  
Vol 100 (9) ◽  
pp. 3340-3347 ◽  
Author(s):  
Stine H. Scheuer ◽  
Kristine Færch ◽  
Annelotte Philipsen ◽  
Marit E. Jørgensen ◽  
Nanna B. Johansen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Adipose Tissue ◽  
Cardiovascular Risk ◽  
Glucose Tolerance ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Fat Distribution ◽  
Men And Women ◽  
Cholesterol Levels

Context:Regional fat distribution rather than overall obesity has been recognized as important to understanding the link between obesity and cardiovascular disease.Objective:We examined the associations of abdominal visceral adipose tissue (VAT) and abdominal subcutaneous adipose tissue (SAT) with cardiovascular risk factors in a Caucasian population of men and women with normal glucose tolerance, prediabetes, or screen-detected diabetes.Design, Setting, and Participants:The study was based on cross-sectional analysis of data from 1412 adults age 45–80 years. VAT and SAT were assessed by ultrasound. The associations of VAT and SAT with blood pressure and lipids were examined by linear regression analysis adjusted for age, sex, smoking, alcohol, physical activity, glucose tolerance status (GTS), medication use, and body mass index. Effect modification by GTS and sex was examined, and stratified analyses performed.Results:Independent of SAT and overall obesity, VAT was associated with higher triglyceride and lower high-density lipoprotein (HDL) cholesterol levels in both men and women and additionally associated with higher total cholesterol in men. SAT was independently associated with higher total cholesterol and low-density lipoprotein cholesterol levels in both sexes, and SAT was additionally associated with higher triglyceride and lower HDL cholesterol levels in women and with higher blood pressure in participants with diabetes.Conclusion:Both abdominal VAT and SAT are independent of overall obesity associated with cardiovascular risk in a population of men and women at low to high risk of diabetes or with screen-detected diabetes.

scholarly journals Trends in the prevalence and management of diabetes in Korea: 2007-2017

2019 ◽  
Vol 41 ◽  
pp. e2019029 ◽  
Author(s):  
Ji-Yeon Shin
Keyword(s):  
Blood Pressure ◽  
Glycemic Control ◽  
Total Cholesterol ◽  
Action Plan ◽  
Glycosylated Hemoglobin ◽  
National Level ◽  
Target Blood Pressure ◽  
Diabetes Diagnosis ◽  
Treatment Rate ◽  
Cholesterol Levels

OBJECTIVES: This study analyzed Korea National Health and Nutrition Examination Survey data from 2007 to 2017 to assess trends in the prevalence, treatment, and control of diabetes in Korean adults ≥30 years of age.METHODS: Prevalent diabetes was defined as a fasting plasma glucose level ≥126 mg/dL, self-reported use of anti-diabetic treatment (insulin or oral anti-diabetic drugs), or diabetes diagnosis by a physician. Target levels were defined as glycosylated hemoglobin <6.5% or <7.0%, blood pressure <130/80 mmHg, and total cholesterol <200 mg/dL. All survey waves were age-standardized to the 2005 Korean census population.RESULTS: Diabetes prevalence increased from 9.6% in 2007-2009 to 10.8% in 2016-2017 (p<0.001). Impaired fasting glucose prevalence significantly increased in both genders and almost every age group. Diabetes awareness and glycemic control did not show an increasing trend; however, the treatment rate and proportion of people diagnosed with diabetes achieving target blood pressure and total cholesterol levels improved from 57.2% to 63.5% (p=0.008), from 41.1% to 53.2% (p<0.001), and from 65.0% to 78.0% (p<0.001), respectively.CONCLUSIONS: From 2007 to 2017, the prevalence of diabetes increased moderately in Korea, whereas the diabetes treatment rate and the proportion of people diagnosed with diabetes achieving target blood pressure and total cholesterol levels improved. However, awareness of diabetes and glycemic control require significant improvements. A national-level action plan is required to raise awareness about diabetes and prediabetes, with the goal of improving glycemic control and minimizing the occurrence of adverse health outcomes.

scholarly journals Causal associations between potentially modifiable risk factors and the Alzheimer’s disease phenome: A Mendelian randomization study

2019 ◽  
Author(s):  
Shea J Andrews ◽  
Brian Fulton-Howard ◽  
Paul O’Reilly ◽  
Lindsay A Farrer ◽  
Jonathan L Haines ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Total Cholesterol ◽  
Cortical Thickness ◽  
Mendelian Randomization ◽  
Hippocampal Volume ◽  
Cortical Surface ◽  
Cholesterol Levels ◽  
Increased Risk ◽  
Reduced Risk

AbstractObjectiveTo evaluate the causal association of 22 previously reported risk factors for Alzheimer’s disease (AD) on the “AD phenome”: AD, AD age of onset (AAOS), hippocampal volume, cortical surface area and thickness, cerebrospinal fluid (CSF) levels of Aβ42, tau, and ptau181, and the neuropathological burden of neuritic plaques, neurofibrillary tangles, and vascular brain injury (VBI).MethodsPolygenic risk scores (PRS) for the 22 risk factors were computed in 26,431 AD cases/controls and the association with AD was evaluated using logistic regression. Two-sample Mendelian randomization was used to evaluate the causal effect of risk factors on the AD phenome.ResultsPRS for increased education and diastolic blood pressure were associated with reduced risk for AD. PRS for increased total cholesterol and moderate-vigorous physical activity were associated with an increased risk of AD. MR indicated that only Education was causally associated with reduced risk of AD, delayed AAOS, and increased cortical surface area and thickness. Total-and LDL-cholesterol levels were causally associated with increased neuritic plaque burden, while diastolic blood pressure and pulse pressure are causally associated with increased risk of VBI. Furthermore, total cholesterol was associated with decreased hippocampal volume; smoking initiation and BMI with decreased cortical thickness; and sleep duration with increased cortical thickness.InterpretationOur comprehensive examination of the genetic evidence for the causal roles of previously reported risk factors in AD using PRS and MR, supports a causal role for education, blood pressure, cholesterol levels, smoking, and BMI with the AD phenome.

Abstract P210: Risk Factors for Intraparenchymal Hemorrhage Subtypes: The Circulatory Risk in Communities Study (CIRCS)

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Tetsuya Ohira ◽  
Eri Eguchi ◽  
Hironori Imano ◽  
Akihiko Kitamura ◽  
Masahiko Kiyama ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Ethanol Intake ◽  
Serum Total Cholesterol ◽  
Intraparenchymal Hemorrhage ◽  
Effective Prevention ◽  
Cholesterol Levels ◽  
Increased Risk

Background: To evaluate risk factors for intraparenchymal hemorrhage (IPH) by its subtypes may contribute to more effective prevention of IPH, but few prospective studies have characterized risk factors for specific subtypes of IPH. Hypothesis: We assessed the hypothesis that the associations between traditional risk factors such as blood pressures and risk of IPH vary by IPH subtype. Methods: A prospective study of Japanese subjects aged 40-69 years was undertaken using the data collected from 9,086 participants (3,560 men and 5,526 women) in cardiovascular risk surveys of three communities between 1985 and 1994. The incidence of IPH between 1985 and 2008 was ascertained by systematic surveillance. The location of hemorrhage was assigned based on admission CT scan or MRI by trained physicians. IPH selectively involving the thalamus, basal ganglia or brainstem was defined as deep IPH, while IPH isolated to the cortex was defined as lobar. The hazard ratios (HRs) of incidence of IPH and its subtypes (deep IPH and lobar or cerebellar IPH) and 95% confidence intervals (CI) relative to the baseline variables were calculated with adjustment for age and other potential confounding factors using the Cox proportional hazards model. Results: During an average follow up of 19.2-years, 139 incident IPHs (103 deep, 31 lobar or cerebellar, and 5 mixed or unclassified IPHs) occurred. Systolic blood pressure, major ST-T abnormality on electrocardiogram, and excess ethanol intake (≥46g/day) were associated with increased risk of deep IPH, while serum total cholesterol levels was inversely associated with incidence of lobar and cerebellar IPH, even after adjustment for potential confounding variables. Serum total cholesterol levels also tended to be inversely associated with incidence of deep IPH, although it did not reach statistically significance. The multivariate-adjusted HRs (95%CI) of deep IPH were 1.14 (1.05-1.23) for systolic blood pressure (10mmHg), 2.09 (1.19- 3.66) for major ST-T abnormality, and 1.86 (1.02- 3.38) for excess ethanol intake. The adjusted HR (95%CI) of lobar and cerebellar IPH was 0.22 (0.07- 0.76) for the participants with higher total cholesterol levels (≥220 mg/dL), compared with those with lower total cholesterol levels (<160mg/dL). There were no associations of diabetes mellitus and smoking with both deep and lobar/cerebellar IPH. Conclusions: Impact of risk factors on incidence of IPH varied according to its subtype.

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