Moderate exercise improves quality of life in patients with non-remitted major depression disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 656-656
Author(s):  
J. Mota Pereira ◽  
J. Silvério ◽  
J.C. Ribeiro ◽  
S. Carvalho ◽  
D. Fonte ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Major Depression ◽  
Study Protocol ◽  
Exercise Group ◽  
Pharmacological Therapy ◽  
Moderate Intensity ◽  
Control Group ◽  
Major Depression Disorder ◽  
Depression Disorder

Prospective, randomized, two-arm, parallel assignment. 150 individuals diagnosed with major depression disorder (MDD) according to DSM-IV-TR criteria, taking combined therapy in doses considered appropriate for at least 9 months, without showing clinical remission, defined as having an HAMD17 total score ≤ 7, attending the out-patient psychiatry clinic, were initially screened through an interview with a psychiatrist. Those meeting study criteria were randomized to one of two groups: control and aerobic exercise. The study protocol was approved by the Institutional Review Board. All participants provided written informed consent. Study protocol Exercise group: individuals were assigned moderate intensity exercise, in addition to their usual pharmacological therapy. Control group: individuals who were not assigned any exercise and remained taking their usual pharmacological therapy. Both groups maintained the pharmacological therapy unchanged during the 12 week study period. All participants were evaluated at baseline (time 0: before starting the physical activity program), and at 4, 8 and 12 weeks for depressive symptoms, functional assessment and Quality of Life.ResultsResults show that participants in the exercise group improved their quality of life parameters, suggesting that exercise could be an effective therapeutic adjuvant for non-remitted MDD patients.

Moderate exercise improves quality of life in patients with non-remitted major depressive disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 657-657
Author(s):  
J. Mota Pereira ◽  
J. Silvério ◽  
S. Carvalho ◽  
J.C. Ribeiro ◽  
D. Fonte ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Exercise Program ◽  
Exercise Group ◽  
Pharmacological Therapy ◽  
Moderate Intensity ◽  
Major Depressive ◽  
Sf 36

IntroductionIn recent years, physical exercise has shown some promising results as an adjuvant therapy for several psychological disorders, helping to improve not only depression parameters but also quality of life. However, and due to the different populations, settings and exercise programs, not all studies have shown a positive association.AimsTo assess the effect of a moderate intensity 12 week exercise program on the quality of life of a population sample of patients with non-remitted Major Depressive Disorder (MDD).MethodsStudy design Prospective, randomized, two-arm, parallel assignment. Population 150 individuals diagnosed with MDD according to DSM-IV criteria, taking combined therapy in doses considered appropriate for at least 9 months, without showing clinical remission, defined as having an HAMD17 total score ≤ 7, attending the out-patient psychiatry clinic, were initially screened through an interview with a psychiatrist. Those meeting study criteria were randomized to one of two groups: control (N = 11) and aerobic exercise (N = 22). Study protocol Exercise group: moderate intensity exercise program for 12 weeks, in addition to their usual pharmacological therapy. Control group: regular daily activities and their usual pharmacological therapy. Instruments WHOQOL-Bref and SF-36, two validated instruments to assess quality of life.ResultsAt the end of the exercise program, participants in the exercise group showed improvement on the physical domain of SF-36 and on the social domain of WHOQOL-Bref (p < 0.05).ConclusionsResults suggest that exercise could help improve some aspects of the quality of life in non-remitted MDD patients.

Poster 153 Factors Influencing Quality of Life Following a Multisite Trial for Major Depression Disorder in SCI

2012 ◽  
Vol 93 (10) ◽  
pp. e57
Author(s):  
Denise G. Tate ◽  
Charles Bombardier ◽  
Allen Heinemann ◽  
Jesse Fann ◽  
Jason Barber ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Major Depression ◽  
Major Depression Disorder ◽  
Factors Influencing ◽  
Depression Disorder

scholarly journals PHYSICAL EXERCISE ON THE RECOVERY OF OBESITY MYOCARDIAL INFARCTION

2021 ◽  
Vol 27 (8) ◽  
pp. 783-785
Author(s):  
Mian Wang ◽  
Fan Wu
Keyword(s):  
Quality Of Life ◽  
Myocardial Infarction ◽  
Physical Exercise ◽  
Nursing Intervention ◽  
Exercise Group ◽  
Control Group ◽  
Level Of Evidence ◽  
Early Exercise ◽  
Physical Functions

ABSTRACT Introduction: Myocardial infarction caused by human obesity can cause a decline in mobility and a decline in the quality of a healthy life. Sports training is beneficial to maintain early physical functions after myocardial infarction. Objective: This article deals with the effect of applying walking aerobic exercise in the rehabilitation treatment of patients with myocardial infarction. Methods: We enrolled 91 patients with myocardial infarction in the early exercise group and 90 patients in the control group. The control group received the routine nursing intervention, and the early exercise group received early physical exercise rehabilitation therapy. Results: The actual quality of life of the early exercise group was higher than that of the control group. The incidence of cardiovascular adverse events was lower than that of the control group. Conclusion: Physical exercise therapy used in acute myocardial infarction can reduce adverse cardiovascular events and improve the quality of life of patients. Level of evidence II; Therapeutic studies - investigation of treatment results.

Abstract 452: Effect of Exercise Training on Sleep Quality and Quality of Life in Post Myocardial Infarction Patients

2016 ◽  
Vol 119 (suppl_1) ◽  
Author(s):  
Jayati Vohra ◽  
Kushal Madan ◽  
Manish Sharma ◽  
J.P.S Sawhney
Keyword(s):  
Quality Of Life ◽  
Myocardial Infarction ◽  
Exercise Training ◽  
Sleep Quality ◽  
Physical Functioning ◽  
Exercise Program ◽  
Exercise Group ◽  
Control Group ◽  
Experimental Group

Objectives: To study the effect of four weeks of aerobic exercise training, on sleep quality and quality of life parameters like anxiety, depression and physical functioning in Post Myocardial Infarction (MI) patients. Methods: ST elevated MI patients (n=21, <65years age) were voluntarily divided into 2 groups, control group (n=11) and exercising group (n=10). The patients in experimental group followed an exercise program of 3 sessions per week for 4 weeks. The subjective quality of life, anxiety and depression levels were assessed by the SF 36 questionnaire and Hospital Anxiety & Depression Scale (HAD scale) and the sleep quality was assessed using Pittsburgh Sleep Quality Index (PSQI). Poor sleep quality and short sleep duration was defined as PSQI > 5 and total sleep time <6hrs. respectively. After 4 weeks of the program the questionnaires were repeated for all 21 patients. Wilcoxon rank order test and Student T test were used. P<0.05 was considered statistically significant Results: Intergroup analysis showed statically significant reduction in anxiety score (9vs0.5) and depression score (3vs0) in exercise group as compared to control group respectively. As compared to control group, exercise group also showed statistically significant improvement in the quality of life parameter score [physical functioning (750vs1000), role functioning physical (0vs400) & emotional (0vs300), energy level (215vs400), emotional well-being (400vs500), social functioning (120vs200), general health (230vs462.5) & health changes (50vs100)]. Intra group analysis also showed significant changes only in exercise group. After 4 weeks of exercise training, PSQI score improved in the experimental group from 9.5±4.11 to 1.13±0.35 (p=0.00029) indicating better sleep quality and duration. While it remained comparable to the baseline values in the control group i.e. from 9.9±4.70 to 10.33±3.87 (p value= 0.514). Conclusion: Four weeks of exercise program improves the quality & duration of sleep and quality of life in MI patients after 2 weeks of index event.

scholarly journals Equine-assisted biographical work (EABW) with individuals in the second half of life: study protocol of a multicentre randomised controlled trial

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Julia Schmidt ◽  
Andrea Wartenberg-Demand ◽  
Simon Forstmeier
Keyword(s):  
Quality Of Life ◽  
Major Depression ◽  
Phase Iii ◽  
Control Group ◽  
Equine Assisted Therapy ◽  
Health Related ◽  
Randomised Controlled ◽  
Equine Assisted ◽  
Subclinical Depression

Abstract Background Equine-assisted therapy is more often practiced with children and adolescents than with the elderly, although individuals in the second half of life could also profit from it. This group, from the age of 50, is characterised by increasing emotional, social, health-related and cognitive changes; a critical life event, such as a neurological illness or loss of a family member, can increase the likelihood of subclinical depression. Individuals who exhibit depressive symptoms not necessarily diagnosed with a major depression may suffer from relevant losses of quality of life (e.g. sleep disorders, memory disorders, feelings of guilt, hopelessness). Despite the fact that the various healthcare systems are in general more frequently used, such individuals often do not receive adequate therapy. The processing of one’s biography (reminiscence) is an elementary component of most psychotherapy approaches and has been demonstrated to treat and prevent the development of major depression. In this study, equine-assisted biographical work (EABW), a combination of equine-assisted therapy and biographical work, will be applied with individuals with subclinical depression in the second half of their life. Methods This is a multicentre, prospective, randomised, controlled and open phase III study in enrolling participants with subclinical depression. The aim of the study is to evaluate whether a preventive, equine-assisted, age-specific treatment combining elements of equine-assisted intervention with those of biographical work offers better treatment potentials in comparison to a control group with no intervention. Study participants in the intervention group will receive weekly equine-assisted biographical work over a period of 8 weeks. The primary endpoint is the change in Beck Depression Inventory-II (BDI-II) in a pre-post comparison. Secondary endpoints include other health-related questionnaires including quality of life, reminiscence functions and anxiety. Discussion The present study is the first randomised study examining the efficacy of biographical work with a horse and has the potential to establish an empirically based treatment for individuals in the second half of life and improving the symptoms of subclinical depression. Trial registration German Clinical Trials Register DRKS00017010. Registered on 01 April 2019

scholarly journals Twelve Weeks of Strengthening Exercise for Patients with Rheumatoid Arthritis: A Prospective Intervention Study

2020 ◽  
Vol 9 (9) ◽  
pp. 2792
Author(s):  
Bomi Sul ◽  
Kyoung Bo Lee ◽  
Young Bin Joo ◽  
Bo Young Hong ◽  
Joon-Sung Kim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Lower Limb ◽  
Exercise Group ◽  
Activity Level ◽  
Control Group ◽  
Intervention Period ◽  
Sf 36 ◽  
Strengthening Exercise

Rheumatoid arthritis (RA) patients may benefit from exercise for several reasons. However, whole-limb strengthening exercises for such patients remain poorly studied. We hypothesized that systemic strength training that includes the upper and lower extremities would improve strength per se and enhance the quality of life. Here, we investigated the effects of 12 weeks of upper- and lower-limb strengthening exercise on the strength and quality of life of RA patients using the International Classification of Functioning, Disability, and Health model. This was a prospective, interventional controlled trial. Forty female RA patients were recruited and assigned to two groups not based on willingness to exercise, with 20 patients in the exercise group and 20 in the control group. All patients in the exercise group received once-weekly training sessions of 60 min over 12 weeks. All participants were assessed before and after the 12-week intervention period. We measured the hand grip strength and isometric quadriceps contraction, the cross-sectional area of the rectus femoris (CSA-RF) (via ultrasonography), and performed the 30 s sit-to-stand test and the 6 min walk test (6MWT). We derived the Borg scale score after the 6MWT and assessed the extent of social participation and quality of life using a Korean version of the 36-Item Short Form Health Survey (SF-36). A total of 35 subjects completed the experiment (18 in the exercise group, 17 in the control group). After the 12-week intervention period, the lower-limb strength and the CSA-RF were significantly increased in the exercise group. The activity level did not change significantly in either group. The exercise group exhibited significant improvements in the SF-36 mental health domain scores. Thus, strengthening exercise is useful for patients with RA.

scholarly journals The Effect of Dignity Therapy on Hope in Patients with Major Depression Disorder

2016 ◽  
Vol 8 (12) ◽  
pp. 118 ◽  
Author(s):  
Saeed Vaghee ◽  
Abbas Heydari
Keyword(s):  
Clinical Trial ◽  
Major Depression ◽  
Therapy Group ◽  
T Test ◽  
Control Group ◽  
Major Depression Disorder ◽  
Dignity Therapy ◽  
Therapy Effect ◽  
Before And After ◽  
Depression Disorder

<p><strong>INTRODUCTION:</strong> Despite the importance of the hope level increment in the patients with major depression disorder, fewer interventions have been applied to improve the hope level in the psychiatric patients, especially the depressed individuals.</p><p><strong>OBJECTIVE:</strong> To identify the dignity therapy effect on the hope level in the patients with major depression disorder.</p><p><strong>METHOD:</strong> In this random controlled clinical trial, 58 patients with major depression disorder, who were hospitalized in Ibn-e-Sina psychiatric hospital of Mashhad, were separated into two intervention (28 individuals) and control (30 individuals) groups. The intervention group has taken the dignity therapy (based on the standard protocol in three 30-45 minutes sessions) and the control group have been undertaken the normal caregiving without intervention. The research tool was the Herth hope index, which was filled exactly before and after intervention. The data analysis has been done by SPSS 11.5 and exact Fischer tests, Chi square, independent t-test and paired t-test.</p><p><strong>RESULTS:</strong> 65.5 percent of the patients were female and 34.5 percent were male. Before the intervention, there was no significant statistical difference between the dignity therapy group (19.9±2.8) and the control group (20.5±1.6) in the average total hope score (p=0.39). However, the variations of the average total hope score before and after intervention between the dignity therapy group (4.7±2.9) and the control group (0.1±1.9) was significant (p&lt;0.001).</p><p><strong>CONCLUSIONS:</strong> According to the dignity therapy effect on the hope level increment in patients with major depression disorder, this unique and short clinical trial can be employed to increase the hope level in the patients with depression disorder.</p>

Can Aerobic Exercise Training Affect Health-Related Quality of Life for People with Multiple Sclerosis?

2001 ◽  
Vol 23 (2) ◽  
pp. 122-135 ◽  
Author(s):  
Georgina Sutherland ◽  
Mark B. Andersen ◽  
Mark A. Stoové
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Bodily Pain ◽  
Well Being ◽  
Exercise Group ◽  
Control Group ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Individuals with multiple sclerosis (MS) are often advised not to participate in vigorous exercise. Leading a relatively sedentary life, however, may exacerbate the debilitating effects of MS. In this study, 22 people participated in either a no-special-activity group (n = 11) or an experimental group (n = 11) that involved water aerobics three times a week for 10 weeks. Measures taken included scales for health-related quality of life (HRQOL) and psychological well-being. ANCOVAs using social support and the appropriate pretest scores as covariates revealed that after the intervention, the exercise group had more energy and vigor (extremely large effect sizes). Other very large effects were found in the exercise group, which had better social and sexual functioning and less bodily pain and fatigue than the control group. Future research should involve long-term studies to determine whether exercise not only improves quality of life but also helps slow the progression of disease.

scholarly journals Serum Cortisol Levels Modifications in Patients with Depression and Irritable Bowel Syndrome

2019 ◽  
Vol 70 (9) ◽  
pp. 3383-3386 ◽  
Author(s):  
Luminita Diana Hritcu ◽  
Manuela Padurariu ◽  
Alin Ciobica ◽  
Cristina Horhogea ◽  
Mihaela Claudia Spataru ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Major Depression ◽  
Present Report ◽  
Serum Cortisol ◽  
Control Group ◽  
Major Depression Disorder ◽  
Related Factors ◽  
Cortisol Levels ◽  
Irritable Bowel ◽  
Depression Disorder

The correlations between depression and stress are quite accepted nowadays, as well as the fact that cortisol levels could also represent fundamental risk factors for major depressive disorder. However, when it comes to the modifications of cortisol levels in depression, the results are controversial. Same goes for the cortisol modifications in irritable bowel syndrome (IBS), which is a functional digestive disorder characterized by a strong biopsychological component, being highly influenced or exacerbated by stressful stimuli. Thus, in the present report we were interested in seeing if there are any serum cortisol levels variations in patients with depression and irritable bowel syndrome, by looking at cortisol modifications in two different groups of patients: a control group with major depression disorder and another study group composed by major depression disorder + IBS patients. Thus, our data presented here are suggesting that there is a significant increase in cortisol levels in the morning serum of the patients with major depression disorder + IBS, as compared to the group having only depression. The results presented here could have an important relevance in the context of managing the stress-related factors in the pathological entities described above.

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