Sexual dysfunction in patients with schizophrenia vs bipolar disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 1542-1542
Author(s):  
E.M. Díaz-Mesa ◽  
M.P. García-Portilla ◽  
S. Al-Halabí ◽  
P.A. Sáiz ◽  
J. Bobes

IntroductionHealthy sexual functioning is an important part of the human experience, but there is a lack of studies regarding sexuality and sexual behavior in schizophrenia and bipolar disorder (García-Portilla, 2010).AimTo determine the differences on the sexual dysfunction profile between patients with schizophrenia and bipolar disorder.MethodNaturalistic, cross-sectional, multicentre, validation study. A total of 89 patients with schizophrenia (SQF) and 82 with bipolar disorder (BPD) were evaluated using the Changes in Sexual Functioning Questionnaire Short-Form (CSFQ-14).ResultsSample description (SQF vs BPD): Mean age (SD) were 39.2 (11.0) vs 46.7 (10.9) (p < 0.001), men were 58.8% vs 41.2% (χ2 = 4.0, df. = 1, p < 0.05), 61.8% vs 38.2% were single (χ2 = 12.8, df. = 1, p < 0.001). Mean (SD) scores on CSFQ-14 scales were (SQF vs BPD): Pleasure 2.2 (1.0) vs 2.6 (1.0) (t = -2.2, p < 0.05), Sexual desire/frequency 5.3 (2.0) vs 5.9 (2.0) (t = -2.0, p < 0.05), Sexual desire/interest 5.7 (2.6) vs 6.9 (3.0) (t = -2.5, p < 0.05), Arousal/excitement 8.6 (3.1) vs 8.9 (3.4), Orgasm/completion 7.9 (3.2) vs 8.8 (3.2), Desire 11.1 (3.9) vs 12.9 (4.4) (t = -2.7, p < 0.05), Arousal 8.6 (3.1) vs 8.9 (3.4), Orgasm 7.9 (3.2) vs 8.8 (3.2) and Total 39.5 (9.7) vs 42.2 (11.0).ConclusionsPatients with schizophrenia have more difficulty to get pleasure and more problems in the phase of desire (frequency and interest) than the patients with bipolar disorder.

2018 ◽  
Vol 46 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Rudolf Puchner ◽  
Judith Sautner ◽  
Johann Gruber ◽  
Elia Bragagna ◽  
Andrea Trenkler ◽  
...  

Objective.To evaluate the effect of rheumatoid arthritis (RA) on impairing women’s sexuality regarding motivation, activity, and satisfaction, and to assess the correlation of disease-related physical impairment within sexual functioning.Methods.An anonymous survey among women with RA and healthy controls (HC) using standardized questionnaires, predominantly the Changes in Sexual Functioning Questionnaire-short form (CSFQ-14). In addition, disease activity, depression, and disability were evaluated.Results.There were 319 questionnaires distributed to patients and 306 to HC. Of these, 235 patient questionnaires (73.7%) and 180 HC questionnaires (58.8%) were returned, of which 203 and 169 were completed, respectively. Of the patients with RA, 47.8% had a total CSFQ-14 score of ≤ 41, indicating female sexual dysfunction (FSD), as compared to 14.2% of HC (p < 0.0001). The median CSFQ-14 score was lower in patients with RA [42 points, interquartile range (IQR) 36–48] than in HC (49 points, IQR 44–54; p < 0.0001), resulting in an OR of 5.53 (95% CI 3.19–9.57; p < 0.0001). After adjustment for confounders, given a higher mean age of patients (55.2 ± 11.3 yrs) than HC (47.4 ± 11.8 yrs; p < 0.0001), the OR for FSD in patients with RA was still 3.04 (95% CI 1.61–5.75; p = 0.001). Neither the Health Assessment Questionnaire–Disability Index nor the Clinical Disease Activity Index was associated with FSD after adjustment.Conclusion.FSD apparently is highly prevalent in female patients with RA, affects all subdomains of sexual function, and is most likely underestimated in daily clinical practice. Of note, FSD could not be linked to disability or RA disease activity.


2020 ◽  
Vol 2 (1) ◽  
pp. 87-92
Author(s):  
Suvarna Jyothi Kantipudi ◽  
Navina Suresh ◽  
Poornima Ayyadurai ◽  
Sathianathan Ramanathan

Background: Sexual dysfunction is common in females with schizophrenia and is attributed to multiple causes, including individual psychopathology and antipsychotics. Understanding the impact of relationship satisfaction on sexual functioning is not widely studied in schizophrenia. Women caregivers also experience sexual problems and were not studied in the past. Aim: To assess the nature and occurrence of sexual dysfunction in women with schizophrenia in comparison to caregivers of males without severe mental disorder. Methods: A cross-sectional study was conducted. A total of 30 women with schizophrenia were recruited as cases and 26 age-matched controls were recruited from female caregivers. All subjects were assessed using standardized tools such as Female Sexual Function Index (FSFI) and Relationship Assessment Scale along with sociodemographic questionnaire. Results: There was a significant difference in FSFI scores and relationship scores between women with schizophrenia and caregiver control subjects. The relationship quality was better in patients with schizophrenia when compared to caregivers unlike sexual functioning. Conclusion: Sexual functioning in women is a complex phenomenon. A holistic biopsychosocial approach is necessary to understand women’s sexual function.


Author(s):  
Hasanul Arifin ◽  
Alfansuri Kadri ◽  
Yuneldi Anwar

  A DESCRIPTION OF SEXUAL DYSFUNCTION, DISABILITY, AND QUALITY OF LIFE OF POST-STROKE PATIENTSABSTRACTIntroduction: Sexual function and disability are post-stroke complications that can affect the long-term quality of life. The problem is being neglected, thus cannot be intervened further. There are simple screenings that can be used to detect the disorder.Aim: To determine the characteristics  of sexual dysfunction, disability and quality of life, and also demographic profile of post stroke patients in Neurology Outpatient Clinic at General Hospital Haji Adam Malik, Medan.Method: A cross sectional descriptive study on poststroke patients in Neurology Outpatient Clinic of General Hospital Adam Malik, Medan between March and July 2018. Subjects were asked to fill three questionnaires; Changes in Sexual Functioning Questionnaire (CSFQ-14) to assess sexual dysfunction, Stroke-Specific Quality of Life (SS-QoL-12) to assess quality of life, and Barthel Index (BI) and modified Rankin Scale (mRS) to assess disability.Results: We identified 45 subjects and the mean of age was 60.27+10.12 years, mostly men (75.6%) and was suffered from ischemic stroke (95.6%). Majority of the subjects (93.3%) were reported of having sexual dysfunction, some have symptoms of disability (35.6%) and full dependence (44.5%). The quality of life was relatively better in male, especially in the physical domain.Discussion: In post stroke population, the prevalence of sexual dysfunction is 93.3%, mostly affected male patients. Majority of the subjects were independent and without significant disability. The quality of life was relatively better in male and the lowest value related to health was the power domain.Keywords: Disability, post-stroke, quality of life, sexual dysfunctionABSTRAKPendahuluan: Salah satu komplikasi pascastroke adalah gangguan fungsi dan disabilitas seksual yang dapat memengaruhi kualitas hidup jangka panjang. Namun hal ini masih terabaikan, hingga tidak dapat diintervensi lebih lanjut. Terdapat beberapa skrining sederhana yang dapat digunakan untuk mendeteksi gangguan tersebut.Tujuan: Untuk mengetahui gambaran disfungsi seksual, disabilitas, dan kualitas hidup pada penderita pascastroke di rawat jalan Neurologi RSUP Haji Adam Malik, Medan.Metode:  Penelitian  deskriptif  dengan  studi  potong  lintang  pada  pasien  pascastroke  di  Poliklinik  Neurologi RSUP Haji Adam Malik, Medan pada bulan Maret–Juli 2018. Subjek diminta mengisi 3 kuesioner, yaitu: Changes in Sexual Functioning Questionnaire (CSFQ-14) untuk menilai perubahan fungsi seksual, Stroke-Specific Quality of Life (SS-QoL-12) untuk menilai kualitas hidup, serta Indeks Barthel (IB) dan modified Rankin Scale (mRS) untuk  menilai disabilitas.Hasil: Didapatkan 45 subjek dengan rerata usia 60,27+10,12 tahun, terutama laki-laki (75,6%) dan menderita stroke iskemik (95,6%). Mayoritas subjek mengalami disfungsi seksual (93,3%), sebagian memiliki gejala disabilitas (35,6%) dan ketergantungan penuh (44,5%). Kualitas hidup relatif lebih baik pada laki-laki dan khususnya pada domain fisik.Diskusi: Didapatkan prevalensi disfungsi seksual sebanyak 93,3% pada pasien pascastroke, terutama laki-laki. Mayoritas subjek pada keadaan mandiri dan disabilitas yang tidak signifikan. Gambaran kualitas hidup secara keseluruhan relatif lebih baik pada laki-laki dengan nilai yang berhubungan dengan kesehatan yang relatif paling rendah adalah domain tenaga.Kata Kunci: Disabilitas, disfungsi seksual, kualitas hidup, pascastroke  


Author(s):  
Virinder Kaur ◽  
Ng Chong Guan ◽  
Jesjeet Singh Gill ◽  
Low Sue-Yin

Aim: This study aims to determine and compare the prevalence of Female Sexual Dysfunction (FSD) between patients on escitalopram and agomelatine, as well as to investigate possible factors associated with their usage. Study Design: Cross-sectional. Place and Duration of Study: Psychiatric Day Care Clinic, Department of Psychological Medicine, University Malaya Medical Centre (UMMC), Malaysia, between November 1, 2020 until February 1, 2021. Methodology: This study is a cross-sectional study involving 66 women with depression from the outpatient psychiatric clinic of a university hospital; 35 of whom were prescribed with escitalopram and 31 with agomelatine. The subjects were in remission and had no significant signs or symptoms of depression for at least 2 months. The prevalence of FSD between the two groups were compared after adjusting for underlying depression severity. Results: This study showed that the overall prevalence rate of FSD was 33.3%, with the prevalence being higher for those on escitalopram (42.9%) than those on agomelatine (22.6%), but did not achieve statistical significance (P=0.081). Out of the six domains of FSD, multivariate analyses revealed that there was a significant reduction of 69% in sexual desire disorder (95% CI:0.110, 0.855), P=0.022 for those on agomelatine compared to escitalopram. Controlling for drug dosage and depression severity (as measured using Montgomery-Asberg Depression Rating Scale), the odds for patients on agomelatine developing sexual desire disorder was 0.267 (95% CI:0.091, 0.783), P=0.016. Conclusion: There was no significant difference in FSD risk between patients on agomelatine and those on escitalopram. Patients on agomelatine were however less likely to develop sexual desire disorder, which demonstrates a slightly better sexual acceptability profile of agomelatine in women in this respect compared to escitalopram.


2021 ◽  
Vol 14 (10) ◽  
pp. 947
Author(s):  
Marek Krzystanek ◽  
Anna Warchala ◽  
Beata Trędzbor ◽  
Ewa Martyniak ◽  
Katarzyna Skałacka ◽  
...  

Sexual dysfunctions in people with schizophrenia are more severe than in the general population and are an important element in the treatment of schizophrenia. The mechanism of sexual dysfunction in patients treated for schizophrenia may be related to the side effects of antipsychotic drugs (hyperprolactinemia, suppression of the reward system), but it may also be related to the pathogenesis of schizophrenia itself. The aim of the study was to present the possibility of using amantadine in the treatment of sexual dysfunction in schizophrenia without the concomitant hyperprolactinemia. In an open and naturalistic case series study, five men treated for schizophrenia in a stable mental state were described. All patients reported a prolonged lack of sexual desire and sexual activity prior to treatment with amantadine. After exclusion of hyperprolactinemia, patients received amantadine 100 mg in the evening. Sexual dysfunction was assessed using subscales of the 14-point Short Form of the Changes in Sexual Functioning Questionnaire (CSFQ-14). On subsequent visits after 1, 2 and 3 months of administration of amantadine, an improvement in sexual functioning was observed in all patients. Although this is only the preliminary report, amantadine may become a new indication for the treatment of sexual dysfunction in schizophrenia patients.


2020 ◽  
Vol 19 ◽  
pp. 1-14
Author(s):  
Alejandro Saavedra-Roa ◽  
Pablo Vallejo-Medina

Las escalas SIS/SES-SF han sido desarrolladas para medir la inhibición y la excitación sexual. El objetivo del presente estudio fue adaptar y validar estas escalas en población colombiana. Para esto, se realizó la adaptación cultural y validación de contenido de las escalas por medio del juicio de siete expertos, y se validaron psicométricamente sobre una muestra de 2125 participantes (1000 hombres y 1125 mujeres). Los hombres contestaron al International Index of Erectile Function y la Premature Ejaculation Diagnostic Tool; mientras que el total de la muestra contestó al Sexual Desire Inventory, al Massachusetts General Hospital-Sexual Functioning Questionnaire y a la Sexual Inhibition/Sexual Excitation Scales-Short Form, todo ello junto a una batería sociodemográfica. El muestreo se realizó de forma virtual a través de Facebook. Los índices de las escalas mostraron una apropiada validez y fiabilidad. Además, para ambos sexos, las escalas mostraron un nivel de invarianza estricto. Las relaciones significativas con las otras medidas dan cuenta de su validez de criterio. Se sugiere el uso del instrumento para continuar con la investigación del Modelo de Control Dual dentro de la sexualidad en Latinoamérica.


2016 ◽  
Vol 10 (5) ◽  
pp. 418-427 ◽  
Author(s):  
Alessandra Diehl ◽  
Sandra Cristina Pillon ◽  
Manoel Antônio dos Santos ◽  
G. Hussein Rassool ◽  
Ronaldo Laranjeira

The aim of this study was to evaluate the potential relationship between self-reported sexual dysfunction, sexual behavior, and severity of addiction of drug users. A cross-sectional design study was conducted at an inpatient addiction treatment unit in Sao Paulo, Brazil, with a sample of 508 male drug users. Sociodemographic data, sexual behavior, and severity of dependence were evaluated.The prevalence of sexual dysfunction was 37.2% and premature ejaculation was 63.8%. Men with sexual dysfunction presented from moderate to severe level of alcohol, tobacco, and other drugs of dependence. The findings from this study are particularly relevant identifying those sociodemographic factors, severity of drug use, and sexual behavior are related to men who experience sexual dysfunction. Health promotion and motivational interventions on sexual health targeted to male drug users can contribute in reducing these at-risk behaviors. More interdisciplinary research is desirable in future in considering men’s sexual health.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
R. Balon

The first challenge in diagnosing female sexual dysfunction(s) originates in our diagnostic system. The traditional model of classifying sexual dysfunction is anchored in the sexual response cycle: desire - arousal - orgasm - resolution. However, as some experts have pointed out, this classification may be problematic in the area of female sexuality. Both the diagnoses of female hypoactive sexual desire disorder (FHSDD) and female arousal disorder (FSAD) probably need to be redefined and refined. Examples include adding the lack of responsive desire to the FHSDD criteria and creating categories of subjective FSAD and genital FSAD.The second challenge in diagnosis female dysfunction is the lack of solid diagnostic instruments, diagnosis-specific laboratory assays and other specific testing. Specific measures of female sexual functioning, such as Female Sexual Functioning Index, Profile of Female Sexual Functioning, Sexual Function Questionnaire, Sexual Desire and Interest Inventory, and Female Sexual Distress Scale were mostly developed as outcome measures. No solid diagnostic instrument for sexual dysfunction exists, not even a version of the Structured Clinical Interview for DSM sexual dysfunctions. The contribution of imaging techniques, such as ultrasonography, magnetic resonance imaging or thermography, to the diagnosis is unclear, and these techniques are far (if ever) from clinical use.Thus, a detailed comprehensive clinical interview combined with physical examination, possibly a gynecological examination, and in some cases laboratory hormonal testing remains the cornerstone of diagnosing and assessing female sexual dysfunctions.


Hypoactive sexual desire disorder in men may occur in the context of poor sexual functioning, secondary to sexual dysfunction or a state of sexual dissatisfaction, or may may correspond to poor functioning of the couple. Thus, these multiple factors can generate a hypoactive sexual desire issue. The disorder of desire may also mean cognitions and / or persistently or recurrently reduced(absent) sexual/ erotic fantasies. Worldwide prevalence of sexual desire disorder in men is occasionally 6% for those 8-24 years old; significantly 41% for those 66-74 years old, and persistently 1,8% for those 16-44 years old. The disorder may emerge from the beginning of the sexual life or begin after a period of relatively normal sexual function. Keywords: hypoactive sexual desire disorder, s-on, therapy, testing, evaluation, sexual disorders.


2019 ◽  
Vol 1 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Ramya Shruthi D. ◽  
Sunil Kumar S. ◽  
Shyam Prasad Shetty ◽  
Nagaraj Desai ◽  
T. S. Sathyanarayana Rao

Introduction: Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality worldwide. Patients with coronary artery disease (CAD) have more than twofold risk of sexual dysfunction compared with age-matched healthy persons. Coronary artery bypass graft (CABG) surgery benefits in CAD populations are well established. Erectile dysfunction (ED) in men and arousal difficulties in women are highly prevalent in CAD, yet it is frequently under-recognized and under-diagnosed in clinical practice. A further study on the relation between CABG and sexual functioning is not much explored, hence the need for the study. Materials and Method: It is a cross-sectional study conducted in JSS Hospital, Mysuru, Karnataka. A total of 54 consecutive patients who have undergone CABG were considered. Informed and written consent was taken. After stabilization and thorough checkup by the attending cardiologist, interview was conducted. The patients were assessed on a structured and validated pro forma, for males International Index for Erectile Function (IIEF) and for females Female Sexual Function Index (FSFI) were used. ANOVA and Student’s t test, statistical software SAS 9.2, SPSS 15.0, Stata 10.1, MedCalc 9.0.1, Systat 12.0, and R environment ver.2.11.1 were used for statistical analysis. Results: Of the 54 study subjects, in males, 69.4% had mild to moderate ED, 52.8% had mild orgasmic dysfunction, 44.4% had moderate desire dysfunction, 50% had mild to moderate dysfunction of intercourse satisfaction, and 44.4% had mild to moderate and moderate dysfunction in overall satisfaction. In females, one or the other forms of sexual dysfunction were present in all the female study subjects; among them, 66.7% had arousal difficulties, 44.4% had lubrication, orgasm, and satisfaction problems and pain difficulties. Conclusion: The results obtained in this study showed an increased prevalence rate of sexual dysfunction in patients who have undergone CABG. Hence addressing the concerned issues during the stay in the hospital is necessary for the better outcomes.


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