Early age at first sexual intercourse and early pregnancy are risk factors for cervical cancer in developing countries

2009 ◽  
Vol 2009 ◽  
pp. 151-152
Author(s):  
L.P. Shulman
2021 ◽  
Vol 6 (11) ◽  
pp. 12-19
Author(s):  
Meryem ÇOLAK ◽  
Merve KARTAL DEMİR

It is important to understand the frequency of Human Papilloma Virus (HPV) and the factors associated with HPV infections, to determine prevention, control and measures to be taken. In this study, it was aimed to investigate the HPV prevalence, genotype distribution and possible risk factors in women applying to the Family Health Center. Sexually active, clinically asymptomatic fifty women aged 30-65 who applied to Safranbolu Family Health Center between October 2018 and March 2019 were included in the study. In order to compare HPV-DNA positivity and socio-demographic characteristics, the education status, number of pregnancies, age of first sexual intercourse, presence of chronic disease, pap smear test and HPV vaccine status, etc. information was recorded and cervical swab samples were taken for detection of HPV-DNA. Viral DNA was isolated with the QIAamp® Viral DNA Kit (QIAGEN, Germany) according to the manufacturer's protocol. The presence of HPV-DNA was investigated using the MY09 / MY11 primers by the Polymerase Chain Reaction (PCR) method, positive samples were amplified using type-specific primers by PCR method and HPV typing was performed. HPV-DNA positivity was detected as 6% (3/50) in the study. Two samples were typed as HPV16; and one samples was typed as HPV31. It was observed that all HPV DNA positive samples were high risk oncogenic HPV types. When the probable risk factors are examined; It was observed that the first sexual intercourse age of patients was 16-21 years, and the number of pregnancies was ≥3 among the HPV-DNA positive women. A statistically significant relation was found with HPV-DNA positivity between the age of first sexual intercourse and the number of pregnancies (p <0.05). HPV-DNA positivity was not observed in any woman protected by a condom, which is considered to be the safest in terms of to protect sexualy transmission infections. It was observed that any women participating in the study knew the availability of HPV vaccine and did not get the HPV vaccine. It is necessary to perform studies showing the prevalence of HPV and common genotypes in a region at certain time intervals; it is thought that the results will guide cervical cancer prevention and vaccination.


2016 ◽  
Vol 5 (8) ◽  
pp. 69-72 ◽  
Author(s):  
Farah Rehan ◽  
Alina Qadeer ◽  
Irfan Bashir ◽  
Mohammed Jamshaid

Cardiovascular diseases (CVDs) have increased the mortality rate both in developing as well as developed countries, however a lower trend in death rates have been seen in developed and high income countries like USA, UK, Australia, Japan and other European countries due to improved life style, better strategic implementation, control of disease both in young and adults and especially reduced smoking habits. In developing countries CVD become an alarming situation due to prevalence of disease in early age that later on become chronic and difficult to control. Various risk factors that can contribute toward CVD in developing countries include smoking, high alcohol and salt intake, dietary factors, diabetes, high blood pressure and psychosocial aspects such as stress, anxiety and depression. Various other factors such as family history and the gender difference also contributing towards the high risk of developing CVD.Rehan et al., International Current Pharmaceutical Journal, July 2016, 5(8): 69-72http://www.icpjonline.com/documents/Vol5Issue8/02.pdf


2017 ◽  
Vol 4 (3) ◽  
pp. 432
Author(s):  
Vita Wulandari

WHO in 2012 as many as 85% of new cases cervical cancer worldwide occur in developing countries. At 2015, Malang have high cervical cancer case of East Java. The purpose of this study to analyze correlation between oral contraceptives use and sexual activity such as the age of first intercourse, age of first pregnancy and abortion with cervical cancer in poly Obstetrics and Gynecology RSUD Dr. Saiful Anwar Malang. This study use case control design. Populastion in this study is an patient poly Obstetrics and Gynecology RSUD Dr. Saiful Anwar Malang who have check-up in November 2015. The number of cases sampel were 37 patient cervical cancer and control sampel were 111 patient not cervical cancer. This study use systematic random sampling with sampling interval. Data were analyzed using Chi Square with α 5%, OR and 95% CI were used to determine the risk factor. The result of this study did not show significant association of oral contraceptives use with cervical cancer. Age of first sexual intercourse < 18 tahun was p =0,0225147014 (OR 2,3194; 95% CI 1,0854 - 4,9561), Age at first pregnancy < 18 tahun was p =0,0236276656 (OR 2,3388; 95% CI 1,0890 – 5,0230), and abortion was p =0,0038911219 (OR 3,2653; 95% CI 1,4593 – 7,3063) show significant association with cervical cancer. The conclusion of this study oral contraceptives use was not correlation with cervical cancer. The age of first intercourse, age at first pregnancy and abortion have correlation with cervical cancer.Keyword: oral contraceptives use, age of first sexual intercourse, age at first pregnancy, abortion, cervical cancer


Author(s):  
Thankamma Ajithkumar ◽  
Ann Barrett ◽  
Helen Hatcher ◽  
Natalie Cook

Cervical cancer is a serious health problem, with nearly 520,000 women developing the disease each year worldwide of whom 443,000 are women in developing countries (Parkin et al. 2005).There are many risk factors from epidemiological to analytical implicated in the development of cervical cancer....


1988 ◽  
Vol 57 (3) ◽  
pp. 326-331 ◽  
Author(s):  
GD Honda ◽  
L Bernstein ◽  
RK Ross ◽  
S Greenland ◽  
V Gerkins ◽  
...  

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Fasogbon Samuel Ayobami

A cervical lesion is an area of abnormal tissue found on the cervix, which is the lower end of a woman’s uterus. The type of the lesion can be atypical squamous cells, squamous intraepithelianeoplasia, and atypical glandular cells. The early stages of cervical cancer may be asymptomatic. In advanced disease, there may be metastases to the abdomen, lungs or any other organ. Infection with some types of human papilloma virus (HPV) is the highest risk factor for cervical cancer which can be transmitted due to multiple sex partners, followed by smoking. Other risk factors include human immunodeficiency virus (HIV), early age at first sexual intercourse, early age at first pregnancy, tobacco use, exposure to passive smoke and other related factors. It is therefore recommended that all the risk factors should be avoided to reduce cervical cancer in the society and women should go for regular cervical screening as early detection can easily be treated.


2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 3s-3s
Author(s):  
J. Agboeze ◽  
M. Nwali ◽  
N. Ezeani

Background: Cervical cancer is a highly preventable disease that affects women especially in developing countries. Over the years awareness and uptake of cervical cancer screening services have remained poor in developing countries. Lack of knowledge and poor attitude toward the disease and risk factors can affect screening practice and development of preventive behavior for cervical cancer. Aim: This study assessed the level of knowledge and barriers toward cervical cancer screening among female university students. Methods: We conducted a cross-sectional survey of 234 female students selected by stratified random sampling techniques at Ebonyi State University Abakaliki Nigeria. A pretested questionnaire was administered to assess knowledge, attitude and screening history. Data were analyzed with Epi info version 7.1.4. Results: Participants' mean age was 22 years (SD=3). Majority of the respondents 79.5% have not heard of screening, 58.9% knew that it can be prevented, 78.5% have not heard about HPV vaccine and only 4.0% have had Papanicolaou test. Common barriers include lack of centers where such services are obtainable (88%) and fear of cancer being discovered (9%). Reported risk factors were multiple sexual partners (24.2%) and early onset of sexual intercourse (19.8%). A significant association was found between institutional and personal barriers and having a Papanicolaou test. Conclusion: Comprehensive education on cervical cancer screening in universities is critical in reducing the morbidity and mortality associated with cervical cancer. Few screening centers have also contributed to poor cervical screening uptake.


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