A Novel Drug Delivery Carrier Based on α-eleostearic Acid Grafted Hydroxyapatite Composite

2014 ◽  
Vol 11 (1) ◽  
pp. 125-133 ◽  
Author(s):  
Ting Cao ◽  
Weili Tang ◽  
Jingchan Zhao ◽  
Lulu Qin ◽  
Chunbo Lan
Keyword(s):  
Drug Delivery ◽  
Eleostearic Acid ◽  
Drug Delivery Carrier ◽  
Hydroxyapatite Composite ◽  
Novel Drug

scholarly journals Nanomedicines as Drug Delivery Carriers of Anti-Tubercular Drugs: From Pathogenesis to Infection Control

2019 ◽  
Vol 16 (5) ◽  
pp. 400-429 ◽  
Author(s):  
Afzal Hussain ◽  
Sima Singh ◽  
Sabya Sachi Das ◽  
Keshireddy Anjireddy ◽  
Subramanian Karpagam ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Patient Compliance ◽  
Health Concern ◽  
Therapeutic Effects ◽  
Drug Delivery Carrier ◽  
Therapeutic Outcomes ◽  
Poor Patient Compliance ◽  
General Aspects ◽  
High Level ◽  
Novel Drug

In spite of advances in tuberculosis (TB) chemotherapy, TB is still airborne deadly disorder as a major issue of health concern worldwide today. Extensive researches have been focused to develop novel drug delivery systems to shorten the lengthy therapy approaches, prevention of relapses, reducing dose-related toxicities and to rectify technologically related drawbacks of anti-tubercular drugs. Moreover, the rapid emergence of drug resistance, poor patient compliance due to negative therapeutic outcomes and intracellular survival of Mycobacterium highlighted to develop carrier with optimum effectiveness of the anti-tubercular drugs. This could be achieved by targeting and concentrating the drug on the infection reservoir of Mycobacterium. In this article, we briefly compiled the general aspects of Mycobacterium pathogenesis, disease treatment along with progressive updates in novel drug delivery carrier system to enhance therapeutic effects of drug and the high level of patient compliance. Recently developed several vaccines might be shortly available as reported by WHO.

scholarly journals A Novel Drug Delivery of Microspheres

2021 ◽  
Vol 11 (6) ◽  
pp. 257-264
Author(s):  
Smily Walia ◽  
J.S. Dua ◽  
D.N. Prasad
Keyword(s):  
Drug Delivery ◽  
Medication Administration ◽  
Magnetic Microspheres ◽  
Target Tissue ◽  
Polymeric Microspheres ◽  
Target Drug Delivery ◽  
Drug Delivery Carrier ◽  
Target Drug ◽  
Medication Delivery ◽  
Novel Drug

Microspheres are multiparticulate drug delivery systems that distribute medications at a predetermined rate to a specific region. Microspheres are free-flowing powders manufactured from biodegradable proteins or synthetic polymers, with particle sizes ranging from 1 to 1000 micrometers. Benefits of using microspheres in medication delivery, bone tissue manufacture, and pollutant absorption and desorption by regeneration .The study demonstrates how microsphere parameters are planned and measured. Bioadhesive microspheres, polymeric microspheres, magnetic microspheres, floating microspheres, and radioactive microspheres are only a few examples of complicated microspheres. Cosmetics, oral medication administration, target drug delivery, ocular drug delivery, gene delivery, and other industries covered in the paper could all benefit from microspheres. To ensure best therapeutic effectiveness, the agent must be delivered to target tissue at an optimal amount during the appropriate timeframe, with low toxicity and adverse effects. There are several methods for delivering the therapeutic substance to the target site in a controlled manner. The use of microspheres as medication carriers is one such technique. The value of microspheres as a novel drug delivery carrier to accomplish site-specific drug delivery was discussed in this article. Keywords: Microspheres, method of preparations, polymer bioadhesion, types of microspheres.

scholarly journals RETRACTED: Novel drug delivery carrier from alginate-carrageenan and glycerol as plasticizer

2017 ◽  
Vol 7 ◽  
pp. 2979-2989 ◽  
Author(s):  
Handoko Darmokoesoemo ◽  
Pratiwi Pudjiastuti ◽  
Bagus Rahmatullah ◽  
Heri Septya Kusuma
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Carrier ◽  
Novel Drug

Albumin-Encapsulated Liposomes: A Novel Drug Delivery Carrier With Hydrophobic Drugs Encapsulated in the Inner Aqueous Core

2018 ◽  
Vol 107 (1) ◽  
pp. 436-445 ◽  
Author(s):  
Yuko Okamoto ◽  
Kazuaki Taguchi ◽  
Keishi Yamasaki ◽  
Mina Sakuragi ◽  
Shun'ichi Kuroda ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hydrophobic Drugs ◽  
Drug Delivery Carrier ◽  
Aqueous Core ◽  
Novel Drug

scholarly journals A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies

2020 ◽  
Vol Volume 15 ◽  
pp. 1161-1172 ◽  
Author(s):  
Saixu Huang ◽  
Zhiyong Huang ◽  
Zhiqin Fu ◽  
Yamin Shi ◽  
Qi Dai ◽  
...  
Keyword(s):  
Drug Delivery ◽  
In Vivo Studies ◽  
Drug Delivery Carrier ◽  
Novel Drug ◽  
Drug Solution

scholarly journals Milk derived colloid as a novel drug delivery carrier for breast cancer

2015 ◽  
Vol 16 (8) ◽  
pp. 1184-1193 ◽  
Author(s):  
Masamichi Hayashi ◽  
Nissim Silanikove ◽  
Xiaofei Chang ◽  
Rajani Ravi ◽  
Vui Pham ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Drug Delivery Carrier ◽  
Novel Drug

scholarly journals Human Serum Albumin: A Novel Drug Delivery Carrier System

2021 ◽  
pp. 18-24
Author(s):  
Snehal Patel ◽  
Chintan Aundhia ◽  
Avinash Seth ◽  
Nirmal Shah ◽  
Dipti Gohil ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Serum Albumin ◽  
Half Life ◽  
Therapeutic Potential ◽  
Specific Binding ◽  
Drug Carrier ◽  
Drug Molecules ◽  
Drug Delivery Carrier ◽  
Specific Binding Sites ◽  
Novel Drug

Serum albumin, often referred to simply as albumin, is a globular protein that in humans is encoded by the ALB gene. Albumin is a multifaceted, highly soluble, stable, nontoxic, non-poisonous, biocompatible and biodegradable plasma protein. Albumin has been widely studied as a protein carrier for drug delivery. Because of its versatile nature, it can also be used for the delivery of the hormones, metals and fatty acids by binding to its specific binding sites. Various studies revealed that albumin can be used to increase the circulating half-life and bioavailability of drug molecules which are smaller than the renal filtration threshold and are rapidly lost from the circulation leading to limiting therapeutic potential. This review article presents advantages, disadvantages, functions, importance, different nanoparticles that can be crowned with an albumin and the special features of albumin as a drug carrier, and how the understanding of these features is currently being employed to optimize the circulatory half-life albumin.

Propylene glycol-embodying deformable liposomes as a novel drug delivery carrier for vaginal fibrauretine delivery applications

2016 ◽  
Vol 226 ◽  
pp. 107-114 ◽  
Author(s):  
Wei-Ze Li ◽  
Xu-Liang Hao ◽  
Ning Zhao ◽  
Wen-Xia Han ◽  
Xi-Feng Zhai ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Propylene Glycol ◽  
Drug Delivery Carrier ◽  
Novel Drug
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