scholarly journals P179 Clinical and evolutionary aspects of inflammatory bowel diseases in a developing country: Morocco. Is there a statistical deviation from developed countries? A university hospital based research

2012 ◽  
Vol 6 ◽  
pp. S80-S81
Author(s):  
F.Z. Ajana ◽  
Y. Cherradi ◽  
W. Essamri ◽  
I. Benelbaghdadi ◽  
A. Essaid
2020 ◽  
Vol 9 (9) ◽  
pp. 2697
Author(s):  
Ferdinando D’Amico ◽  
Patrick Netter ◽  
Cedric Baumann ◽  
Muriel Veltin ◽  
Camille Zallot ◽  
...  

Technological progress, including virtual clinics, web or smartphone-based applications, and assessment of fecal calprotectin (FC) at home has favored the implementation of treat to target strategies for patients with inflammatory bowel diseases (IBD). Although these innovations are promising and have been associated with a significant reduction in health costs, their application in clinical practice is limited. Here, we summarize the most recent literature on virtual clinics and available FC home tests. In addition, we report the experience of IBD patients monitored through the IBDoc® test at the Nancy University Hospital, focusing on usability testing and patient’s satisfaction. This pilot experience shows that a virtual calprotectin clinic doubles adherence rate to FC in IBD patients. This finding is especially clinically relevant in the post-coronavirus disease 2019 (COVID-19) pandemic era, with an increasing use of e-health.


2021 ◽  
Vol 10 (23) ◽  
pp. 5575
Author(s):  
Silvia Salvatori ◽  
Francesco Baldassarre ◽  
Michelangela Mossa ◽  
Giovanni Monteleone

Background and aims. SARS-CoV-2-infected patients can experience long-lasting symptoms even after the resolution of the acute infection. This condition, defined as Long COVID, is now recognized as a public health priority and its negative impact on the quality of life of the patients could be more relevant in individuals with debilitating pathologies. We here evaluated the frequency of Long COVID in patients with inflammatory bowel diseases (IBD). Methods. IBD patients afferent for scheduled visits to our tertiary referral center at the Tor Vergata University Hospital, Rome, were recruited from 7 September to 22 October 2021. During the visits, patients were investigated about previous COVID-19 infection and the possible development of Long COVID. Results. Fifty-three out of 528 IBD patients (10%) have had a SARS-CoV-2 infection. Of these, 21 patients (40%) developed Long COVID, and asthenia was the more frequent symptom as it occurred in nearly two-thirds of patients. Patients with Long COVID were more frequently females, while other clinical and demographic characteristics did not differ between patients with Long COVID and those without Long COVID. In particular, the IBD relapses occurred with the same frequency in the two groups. Conclusions. Long COVID appears to be common in IBD patients even though it does not influence the IBD course.


2020 ◽  
Vol 22 (4) ◽  
pp. 148-155
Author(s):  
D. S. Purgina ◽  
M. V. Solovyev ◽  
L. V. Lyalina ◽  
V. V. Rassokhin

Epidemiological features and clinical variants of inflammatory bowel diseases in St. Petersburg in conditions of outpatient practice are considered. It was established that among patients suffering from ulcerative colitis in the Vyborg and Frunze regions, women predominate in a ratio of 1:2. At the same time, more than 50% of cases of ulcerative colitis and Crohns disease come from the age of 2049 years. The vast majority of patients examined with ulcerative colitis experienced a moderate attack. In more than half of cases, left-sided localization was noted with endoscopic activity of 23 points on the Schroeder scale, rectal lesion was observed in 22% of cases, total colitis was detected in only 14%. In general, the incidence and prevalence of ulcerative colitis in the Vyborg and Frunze regions is higher than Crohns disease. However, more extensive and lengthy studies of the problem are needed, but there are some difficulties associated with the lack of a unified registration base for patients suffering from inflammatory bowel diseases. Given that the incidence of ulcerative colitis and Crohns disease is higher among women and more than 50% of patients are of the most able-bodied age (2049 years), inflammatory bowel disease is a group of highly relevant and socially significant diseases. Lower figures for the incidence and prevalence of inflammatory bowel diseases compared with those of developed countries indicate insufficient detection, diagnostic and clinical features of these diseases, as well as the need to optimize specialized medical care in places of residence of patients suffering from inflammatory bowel diseases. Nevertheless, currently in St. Petersburg and the Leningrad Region a fairly effective system of early detection and dynamic observation of patients suffering from ulcerative colitis has been created, which includes the activities of therapists and gastroenterologists of polyclinics, endoscopists and specialists of centers for the treatment of inflammatory bowel diseases of academic and university clinics.


2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S236-S237
Author(s):  
I MARAFINI ◽  
L Longo ◽  
S Salvatori ◽  
D Miri Lavasani ◽  
F Pianigiani ◽  
...  

Abstract Background Inflammatory bowel diseases (IBD) are associated with mental disorders, which can negatively influence the course of IBD. Nonetheless, psychiatric disorder comorbidities (PDCs) remain undiagnosed in many IBD patients. The aim of this study was to assess the frequency of undiagnosed psychiatric comorbidities in IBD patients. Methods Two-hundred-thirty-seven adult IBD [136 Crohn’s disease (CD) and 101 with ulcerative colitis (UC)] outpatients were consecutively recruited in a single university hospital centre between January 2018 and June 2019. After the visit for IBD clinical evaluation, participants completed self-report questionnaires and then underwent a clinical interview by a trained psychiatrist. Results One-hundred-fourteen (48%) IBD patients had at least one undiagnosed psychiatric disorder. Forty-three (18%) patients presented a single PDC, 40 (16.8%) had two PDCs, 11 (4.6%) had 3 PDCs, 12 (5%) had 4 PDCs, 7 (2.9%) had 5 PDCs and 1 (0.4%) had 6 PDCs. PDCs were equally distributed among CD (72/136, 53%) and UC (42/101, 42%) patients. Mood disorders (54/114, 47%) and anxiety (27/114, 24%) disorders were the most common PDC; moreover, 23 (20%) patients suffered from post-traumatic stress disorder (PTSD), 3 (3%) had an obsessive-compulsive disorder, and 7 (6%) a substance abuse/dependence disorder. Fifty-nine per cent of IBD patients diagnosed with a psychiatric disorder during the study did not have a positive psychiatric anamnesis. PDCs were not related to activity, phenotype or localisation of IBD. Conclusion Psychiatric disorders are common in IBD but not related to activity, phenotype or localisation of bowel disease. Overall, these findings suggest the necessity to include psychiatric evaluation in the management of IBD patients.


2019 ◽  
Vol 14 (2) ◽  
pp. 267-273 ◽  
Author(s):  
Manasi Agrawal ◽  
Johan Burisch ◽  
Jean-Frederic Colombel ◽  
Shailja C. Shah

Abstract The inflammatory bowel diseases [IBDs], inclusive of Crohn’s disease [CD] and ulcerative colitis [UC], are chronic, progressive immune-mediated diseases associated with high morbidity and substantial economic impact. The pathogenesis implicates a complex interaction between environmental determinants and genetic susceptibility. Of concern, the incidence and prevalence of IBD are increasing globally, with the highest relative increase observed in developing and recently developed countries. One high-risk yet underappreciated population is immigrants from countries of low to high IBD incidence, as evidenced by epidemiologic studies demonstrating higher risk of IBD among second- versus first-generation and younger versus older immigrants from low- to high-incidence countries [LTHICs]. The reasons underlying these emerging patterns among immigrants are incompletely understood and provide enormous opportunities to better define the pathophysiology of IBD and move toward disease prevention or at least earlier diagnosis. The rapidity of this epidemiologic shift in the demographic profile of IBD, which was traditionally a disease of Caucasians in industrialized countries, strongly implicates non-genetic factors and gene–environment interactions in the pathophysiology of IBD among immigrants from LTHICs. The primary objectives of this Viewpoint are to [1] provide a focused overview of IBD epidemiology among immigrants from countries at differential IBD risk; [2] emphasize the potential to advance our understanding of IBD pathogenesis via targeted research efforts to delineate risk and protective determinants in this cohort; and [3] highlight disparities and barriers in IBD care, as well as the economic implications of the rising, yet underappreciated, disease burden among immigrants from LTHICs.


2020 ◽  
Vol 9 (5) ◽  
pp. 1387
Author(s):  
Irene Marafini ◽  
Lucia Longo ◽  
Damun Miri Lavasani ◽  
Rodolfo Rossi ◽  
Silvia Salvatori ◽  
...  

Inflammatory bowel diseases (IBD) are associated with comorbid depressive and anxiety disorders, but a significant proportion of IBD patients with psychiatric disorders (PsychD) remain undiagnosed and untreated. The aim of this study was to assess the frequency and type of undiagnosed PsychD in IBD patients. Two hundred and thirty-seven adult IBD (136 Crohn’s disease (CD) and 101 ulcerative colitis (UC)) outpatients were consecutively recruited at a single university hospital centre between January 2018 and June 2019. After a scheduled follow-up visit for IBD clinical evaluation, participants underwent a semi-structured interview with a trained psychiatrist. One hundred and fourteen (48%) IBD patients had at least one PsychD, and in 67 (59%) of them, a diagnosis was made for the first time during the study. The remaining 47 (41%) patients had received a previous psychiatric diagnosis, but in only six cases was it consistent with the diagnosis made during the study. PsychD were equally distributed in CD (72/136, 53%) and UC (42/101, 42%), and mostly represented by mood disorders (54/114, 47%) and anxiety (27/114, 24%) disorders. PsychD were not related to the disease severity, phenotype or localisation of IBD, even though having three or more concomitant PsychD was associated with more severe disease in CD. Our data indicate that undiagnosed PsychD are common in IBD and highlight the importance of considering psychiatric evaluation in the management of IBD patients.


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