The Effect of 2,4 Dimethylamine salt on the Blood, Liver and Muscle of Oryclotagus Cuniculus

Aminoforce containing 720g/l of 2,4-dimethylamine salt induced changes on some enzymes and electrolytes in the male Oryclotagus cuniculus (New Zealand rabbit) were assayed. The organisms were exposed to varying sub-lethal concentrations of the toxicant (720g/l). The concentrations were prepared by pipetting 0.4mls, 0.8mls and 0.12mls making it up to 1.5L clean water in a metal container to make 2.0 mgl-1, 4.0 mgl-1 and 6.0 mgl-1. Aspartate amino transferase (AST), Alanine amino transferase (ALT) and Acid phosphatase (ACP) were assayed in the liver and blood. Results showed that aspartate amino transferase values in the liver and blood were significant (p<0.05) across the concentration of the toxicants. Aspartate amino transferase increased as the concentration of the toxicant increased in the liver, and decreased as the toxicant concentration increased in the blood. Alanine amino transferase in the blood and liver were akin to AST while ACP values increased in the blood and decreased in the liver as the concentration of the toxicant increased. Electrolytes (Sodium (Na+), potassium (K+) and magnesium (Mg2+) ions) showed statistical deviation across the various concentration of the toxicants. Chloride ion values stabilized in the experimental group being not significantly different (p>0.05) across the various concentration of the toxicants. From the study, AST, ALT and ACP are suitable biomarkers for showing sub-lethal effect of aminoforce on Oryclotagus cuniculus. The effects recorded clearly unveiled the potential effect of this xenobiotics on Oryclotagus cuniculus. Therefore, exposure of Oryclotagus cuniculus to this toxicant will affect the organism’s physiological responses and over prolong period of time it could lead to death. Additionally, via food chain man may be affected. The use of this toxicant close to rabbittory should be done with utmost caution.

Quantitative analysis of intracranial electrocorticography signals using the concept of statistical parametric mapping

Statistical parametric mapping (SPM) is a technique with which one can delineate brain activity statistically deviated from the normative mean, and has been commonly employed in noninvasive neuroimaging and EEG studies. Using the concept of SPM, we developed a novel technique for quantification of the statistical deviation of an intracranial electrocorticography (ECoG) measure from the nonepileptic mean. We validated this technique using data previously collected from 123 patients with drug-resistant epilepsy who underwent resective epilepsy surgery. We determined how the measurement of statistical deviation of modulation index (MI) from the non-epileptic mean (rated by z-score) improved the performance of seizure outcome classification model solely based on conventional clinical, seizure onset zone (SOZ), and neuroimaging variables. Here, MI is a summary measure quantifying the strength of in-situ coupling between high-frequency activity at >150 Hz and slow wave at 3–4 Hz. We initially generated a normative MI atlas showing the mean and standard deviation of slow-wave sleep MI of neighboring non-epileptic channels of 47 patients, whose ECoG sampling involved all four lobes. We then calculated ‘MI z-score’ at each electrode site. SOZ had a greater ‘MI z-score’ compared to non-SOZ in the remaining 76 patients. Subsequent multivariate logistic regression analysis and receiver operating characteristic analysis to the combined data of all patients revealed that the full regression model incorporating all predictor variables, including SOZ and ‘MI z-score’, best classified the seizure outcome with sensitivity/specificity of 0.86/0.76. The model excluding ‘MI z-score’ worsened its sensitivity/specificity to 0.86/0.48. Furthermore, the leave-one-out analysis successfully cross-validated the full regression model. Measurement of statistical deviation of MI from the non-epileptic mean on invasive recording is technically feasible. Our analytical technique can be used to evaluate the utility of ECoG biomarkers in epilepsy presurgical evaluation.

Randomness of Poisson Distributed Random Number in the Queue System

In the queuing system, inter arrival variable and service time variable are probabilistic and its pattern follow a Poisson distribution. Simulations experiment for performance measurement of a queuing system required random data. In practice, random data is built using an application program. Pseudorandom data generated from application programs often have different patterns of randomness, although in each experiment simulated the same data distribution. Level of randomness may cause the results of simulation experiments experienced statistically significant deviations, especially on problems with stochastic variables. Statistical deviation can cause errors in interpreting the results of simulation experiments, especially in the assessment of the performance of the queuing system. It is required to evaluate whether the level of randomness of pseudorandom data effect on simulation results of performance measurement of a system. Simulation experiments on a simple queuing system (M / M / 1) was carried out by using a pseudorandom number generator. Application program used to generate pseudorandom numbers is Fortran90. The experimental results show that the greater the amount of pseudorandom data, the greater the statistical deviations occur, and the smaller the degree of randomness of data. This affects the results of the simulation system in which there is a probabilistic variable that require random data to conduct simulation

Age of puberty and conception rates of Hungarian Merino, (Merino x Somali) F1 and (Merino x Barbados Blackbelly) F1 ewes

The aim of our examination was to detect the puberty of the Hungarian Merino and its hairsheep crossbred ewes, and also to determine their average conception rates after having ram exposed in May and June. Hormon diagnostation was used to evaluate the exact date of the very first ovulation. Ultrasound technique was used for checking the conception rates of ewes. The pregnancy detection was applied after a month of the date of taking off the ram.We evaluated the ages of ewes at puberty. Statistical deviation and standard error were calculated. The results proved the Hungarian Merino x Somali (N=10), ((x ± s) = 173 ± 43) and also the Hungarian Merino x Barbados Blackbelly crossbred genotypes (N=7), ((x ± s) = 186 ± 19) have their puberty much earlier as compared to the fullbred Hungarian Merino ewes (N=10), ((x ± s) = 231 ± 95). We experienced the highest conception rate in the group of the (Hungarian Merino x Somali) F1 ewes after exposing the ram in the „out-of season” period of time.

The influence of physical, chemical and biological manipulations on surface potential of calcium phosphate coatings on metal substrates

The electret voltage indices of artificial surfaces are dependent on coatings formation technology and may be regulated by means of change in their physical-chemical parameters. Chemical modification of radio frequency magnetron calcium phosphate coatings (RFMCPC) by means of silicious incorporation led to an augmentation of pieces’ electrostatic potential. A complication of RFMCPC relief that was fixed by roughness index Ra is accompanied by increase in electret voltage index of artificial surface and its statistical deviation. Bone marrow cells suspension in model biological electrolyte populated RFMCPC dimples. In this manner it modulated the amplitude and leveled out the differences of surface electrostatic potential.

Modalities of Civil-Military Stability in Africa

If during the 1960s the coup d'état emerged as the most visible and recurrent characteristic of the African political experience, by the 1980s quasi-permanent military rule, of whatever ideological hue, had become the norm for much of the continent. At any moment in time, up to 65 per cent of all Africa's inhabitants and well over half its states are governed by military administrators. Civilian rule is but a distant memory in some countries. Few at some stage or another have not been run by an armed-forces junta, and fewer still have not been rocked at least once by an attempted coup, putsch, or military-sponsored plot. According to one tabulation, ‘only six states have not witnessed some form of extra-legal armed involvement in national politics since 1958’.1 The phenomenon has even reached the non-state Homelands of Bophuthatswana, Transkei, and Ciskei in South Africa. Rule by civilians is very much the statistical ‘deviation’ from the continental norm, as military leaders lay a permanent claim to the political throne in much of Africa