scholarly journals The Prevalence and Incidence of Frontotemporal Dementia: a Systematic Review

Author(s):  
David B. Hogan ◽  
Nathalie Jetté ◽  
Kirsten M. Fiest ◽  
Jodie I. Roberts ◽  
Dawn Pearson ◽  
...  

AbstractBackgroundPopulation-based prevalence and incidence studies are essential for understanding the burden of frontotemporal dementia (FTD).MethodsThe MEDLINE and EMBASE databases were searched to identify population-based publications from 1985 to 2012, addressing the incidence and/or prevalence of FTD. References of included articles and prior systematic reviews were searched for additional studies. Two reviewers screened all abstracts and full-text reviews, abstracted data and performed quality assessments.ResultsTwenty-six studies were included. Methodological limitations led to wide ranges in the estimates for prevalence (point prevalence 0.01-4.6 per 1000 persons; period prevalence 0.16-31.04 per 1000 persons) and incidence (0.0-0.3 per 1000 person-years). FTD accounted for an average of 2.7% (range 0-9.1%) of all dementia cases among prevalence studies that included subjects 65 and older compared to 10.2% (range 2.8-15.7%) in studies restricted to those aged less than 65. The cumulative numbers of male (373 [52.5%]) and female (338 [47.5%]) cases from studies reporting this information were nearly equal (p=0.18). The behavioural variant FTD (bvFTD) was almost four times as common as the primary progressive aphasias.ConclusionsPopulation-based estimates for the epidemiology of FTD varied widely in the included studies. Refinements in the diagnostic process, possibly by the use of validated biomarkers or limiting case ascertainment to specialty services, are needed to obtain more precise estimates of the prevalence and incidence of FTD.

Author(s):  
David B. Hogan ◽  
Kirsten M. Fiest ◽  
Jodie I. Roberts ◽  
Colleen J. Maxwell ◽  
Jonathan Dykeman ◽  
...  

ABSTRACTBackgroundPopulation-based prevalence and incidence studies are essential for understanding the societal burden of dementia with Lewy bodies (DLB).MethodsThe MEDLINE and EMBASE databases were searched to identify publications addressing the incidence and/or prevalence of DLB. References of included articles and prior systematic reviews were searched for additional studies. Two reviewers screened all abstracts and full-text reviews, abstracted data and performed quality assessments.ResultsTwenty-two studies were included. Incidence rates ranged from 0.5 to 1.6 per 1000 person-years. DLB accounted for 3.2-7.1% of all dementia cases in the incidence studies. Point and period prevalence estimates ranged from 0.02 to 63.5 per 1000 persons. Increasing prevalence estimates were reported with increasing age. DLB accounted for from 0.3 to 24.4% of all cases of dementia in the prevalence studies.ConclusionsDLB becomes more common with increasing age and accounts for about 5% of all dementia cases in older populations.


2021 ◽  
Author(s):  
Samar Khalifa

Abstract Background: Frontotemporal dementia is a common type of dementia and is a group of progressive neurodegenerative syndromes usually caused by the accumulation of pathological tau or TDP-43 proteins. The review is identifying the clinical measures including neuropsychological scores and functional measures. Methods: A systematic review was conducted covering the clinical trials done to investigate the Frontotemporal Dementia. The sample was taken from Pubmed library. 28 results were found in a range of time from 2016 to 2021. The excluded papers were 17. Results: A total of 10,349 articles were identified at the first stage of papers selecting. All records were screened in order to include and exclude by title/abstract and then based on full text. After excluding articles by year and type of papers, a total of 28 articles were identified through the databases. Following this, the irrelevant papers from databases were removed from original articles, and finally 11 articles were included based on their title/abstract. Full articles were then sourced for about 600 references. It included 732 patients and 195 controls as a total. Conclusions: The review describes the clinical and RCT trials for FTD in the last five years so it can be very updated information for the researchers to cover information required for their researches in the future ones.


Author(s):  
Yongjie Yon ◽  
Christopher Mikton ◽  
Zachary D. Gassoumis ◽  
Kathleen H. Wilber

RÉSUMÉLa maltraitance des personnes âgées est un important problème de santé publique et de droits de l’homme. Néanmoins, notre connaissance de la veritable ampleur du phénomène demeure limitée. Pour y remédier, nous allons procéder à une revue systématique et une méta-analyse des études de prevalence de la maltraitance des personnes âgées dans le monde entier. Ce protocole décrit l’approche méthodologique qui sera adoptée pour la réalisation de la revue systématique et de la méta-analyse. En particulier, le protocole décrit le développement des stratégies de recherche et des critères pour identifier et sélectionner les études de prévalence ainsi que la façon dont les données des études sélectionnées seront extraites pour l’analyse. Le protocole décrit également l’approche analytique qui sera utilisée pour calculer les estimations de prevalence et l’utilisation de méta-régression pour évaluer la façon dont les caractéristiques des études influencent les estimations de la prévalence. Ce protocole est conforme au “Preferred Reporting Items for Systematic reviews and Meta-Analysis” – ou PRISMA – et a été enregistré auprès du registre de revues systématique PROSPERO International Prospective Register.


2002 ◽  
Vol 47 (9) ◽  
pp. 833-843 ◽  
Author(s):  
Elliot M Goldner ◽  
Lorena Hsu ◽  
Paul Waraich ◽  
Julian M Somers

Objective: To present the results of a systematic review of the literature published between January 1, 1980, and December 31, 2000, that reports findings on the prevalence and incidence of schizophrenia and related disorders. Method: We conducted a literature search of schizophrenia-related epidemiological studies, using Medline and HealthSTAR databases and canvassing English-language publications. We used a set of predetermined inclusion-exclusion criteria to identify relevant studies. Eligible publications were restricted to age ranges of 18 years and over for prevalence studies and 15 years and over for incidence studies. Prevalence and incidence data were extracted and analyzed for heterogeneity. Results: A total of 18 prevalence and 8 incidence studies met eligibility criteria for the review. Heterogeneity analysis revealed significant differences across 1-year and lifetime prevalence and 1-year incidence of schizophrenia. The corresponding pooled rates were: 0.34 per 100, 0.55 per 100, and 11.1 per 100 000, respectively; the variation in rates between studies was generally between 2- and 5-fold. Conclusions: Although we restricted this review to studies using rigorous and relatively homogeneous methods, there remains significant heterogeneity of prevalence and incidence rates. This strengthens support for the hypothesis that there is real variation in the distribution of schizophrenia around the world. Health planners need to have local data on schizophrenia rates to improve the accuracy of their interventions, while clinicians and researchers need to continue to investigate the etiology of this variation.


2016 ◽  
Vol 20 (5) ◽  
pp. 902-916 ◽  
Author(s):  
Natália Miranda Jung ◽  
Fernanda Souza de Bairros ◽  
Marcos Pascoal Pattussi ◽  
Sílvia Pauli ◽  
Marilda Borges Neutzling

AbstractObjectiveThe present review aimed to identify and synthesize literature on household food insecurity with respect to whether the respondent was male or female.DesignA systematic review of prevalence studies followed by a meta-analysis was conducted between 28 August 2014 and 19 October 2014 in seven electronic databases. The search was updated in April 2016. The included studies used experience-based measures to assess household food insecurity. Dichotomous measures of food insecurity were used. Pooled odds ratios of household food insecurity prevalence in women v. men were obtained through random-effect modelling. Quality assessment, publication bias diagnostics and subgroup analysis were also performed.SettingPopulation-based studies (i.e. non-clinical populations).SubjectsParticipants aged 18 years or over.ResultsOut of the 5145 articles initially identified, forty-two studies with a total population of 233 153 were included. In general, results showed that the odds for household food insecurity was 40 % higher in studies where women were the respondent (95 % CI 1·27, 1·54; P<0·001). Besides, subgroup analysis revealed that female-headed households were 75% (95 % CI 49–96%) more likely to be food insecure than male-headed households.ConclusionsOur results confirm the existence of gender differences in reporting household food insecurity. Furthermore, they indicate that households headed by women constitute a segment of the population that is particularly vulnerable to food insecurity.


2016 ◽  
Vol 23 (13) ◽  
pp. 1531-1545
Author(s):  
Jamal M. Alkhateeb ◽  
Muna S. Alhadidi

Objective: No systematic reviews could be identified in the literature that address ADHD research in Arab countries. In an attempt to help fill this gap, this systematic review was undertaken. Method: An electronic literature search of ADHD studies carried out in Arab countries was done by using Google Scholar, PsycINFO, PubMed, Education Resources Information Center (ERIC), and Arabpsynet. Results: The search yielded 58 studies (10 studies on psychoeducational and social aspects of ADHD, 26 prevalence studies and two reviews of epidemiology of ADHD, and 22 studies on risk factors and comorbidities in ADHD). Conclusion: Although there has been an increase in ADHD research in Arab countries in recent years, this research remains relatively sparse and used methods and procedures that limit the generalizability of the findings.


2019 ◽  
Author(s):  
Lalit Krishna ◽  
Yaazhini Renganathan ◽  
Kuang Teck Tay ◽  
Benjamin Jia Xing Tan ◽  
Jia Yan Chong ◽  
...  

Abstract Introduction: Mentoring studies have gone through great lengths to differentiate mentoring from teaching, tutoring, role modelling, coaching and supervision in efforts to better understand mentoring processes. This review seeks to evaluate the notion that teaching, tutoring, role modelling, coaching and supervision may in fact be part of the mentoring process. To evaluate this theory, this review scrutinizes current literature on teaching, tutoring, role modelling, coaching and supervision to evaluate their commonalities with prevailing concepts of novice mentoring. Methods: A three staged approach is adopted to evaluate this premise. Stage one involves four systematic reviews into teaching, tutoring, role modelling, coaching and supervision published between 1st January 2000 and 31st December 2018. Braun and Clarke’s (2006) approach to thematic analysis was used to identify key elements within these approaches and facilitate comparisons between them. Stage two will provide an updated view of novice mentoring to contextualize the discussion. Stage three infuses mentoring into the findings delineated in stage one. Results: 17499 citations were reviewed, 235 full-text articles were reviewed, and 104 articles were thematically analysed. Four themes were identified – characteristics, processes, nature of relationship, and problems faced in each of the four educational roles. Discussion: Role modelling, teaching and tutoring, coaching and supervision lie within a mentoring spectrum of increasingly structured interactions assisted by assessments, feedback and personalised support that culminate with a mentoring approach. Still requiring validation these findings necessitate a reconceptualization of mentoring and changes to mentor training programs and how mentoring is assessed and supported.


2021 ◽  
Vol 109 (1) ◽  
Author(s):  
Christy Jarvis ◽  
Joan Marcotte Gregory ◽  
Alison Mortensen-Hayes ◽  
Mary McFarland

Background: With the mandate to review all available literature in the study’s inclusion parameters, systematic review projects are likely to require full-text access to a significant number of articles that are not available in a library’s collection, thereby necessitating ordering content via interlibrary loan (ILL). The aim of this study is to understand what effect a systematic review service has on the copyright royalty fees accompanying ILL requests at an academic health sciences library.Case Presentation: The library created a custom report using ILLiad data to look specifically at 2018 ILL borrowing requests that were known to be part of systematic reviews. This subset of borrowing activity was then analyzed to determine its impact on the library’s copyright royalty expenditures for the year. In 2018, copyright eligible borrowing requests that were known to be part of systematic reviews represented only approximately 5% of total filled requests that involved copyright eligible borrowing. However, these systematic review requests directly or indirectly caused approximately 10% of all the Spencer S. Eccles Library copyright royalty expenditures for 2018 requests.Conclusion: Based on the sample data set, the library’s copyright royalty expenditures did increase, but the overall financial impact was modest.


2004 ◽  
Vol 34 (7) ◽  
pp. 1339-1346 ◽  
Author(s):  
M. B. LAURITSEN ◽  
C. B. PEDERSEN ◽  
P. B. MORTENSEN

Background. Based on prevalence studies and the few incidence studies of pervasive developmental disorders (PDDs) the prevalence and incidence of these disorders have been claimed to be increasing.Method. The annual and age-specific prevalence and incidence rates of childhood autism, atypical autism, Asperger's disorder, and pervasive developmental disorder not otherwise specified (PDD-NOS) in Denmark during the period 1971–2000 in children younger than 10 years were estimated using data from the Danish Psychiatric Central Register.Results. A total of 2·4 million children younger than 10 years were followed and 2061 cases with the PDDs studied were identified. Generally, the prevalence and incidence rates of the PDDs studied were stable until the early 1990s after which an increase in the occurrence of all disorders was seen, until 2000. The annual incidence rate per 10000 children younger than 10 years was 2·0 for childhood autism, 0·7 for atypical autism, 1·4 for Asperger's disorder, and 3·0 for PDD-NOS in 2000. We calculated a ‘corrected’ prevalence of childhood autism at 11·8, atypical autism at 3·3, Asperger's disorder at 4·7, and PDD-NOS at 14·6 per 10000 children younger than 10 years on 1 January 1 2001.Conclusions. We found that the estimated prevalences of the PDDs studied were probably underestimated. Furthermore, the increasing prevalence and incidence rates during the 1990s may well be explained by changes in the registration procedures and more awareness of the disorders, although a true increase in the incidence cannot be ruled out.


2021 ◽  
pp. jim-2021-001846
Author(s):  
Danny Juan Avalos ◽  
Jinendra Satiya ◽  
Alberto Contreras ◽  
Shivani Trivedi ◽  
Luis Alvarado ◽  
...  

Latin America has experienced a rise in the prevalence and incidence of inflammatory bowel disease (IBD). Differences in IBD phenotype between Hispanics in Latin America and those in the USA have not been described. We conducted a systematic review with meta-analysis of population-based and cohort studies comparing the phenotype of ulcerative colitis (UC) and Crohn’s disease (CD) in Latin Americans and US Hispanics. A systematic search was conducted up to March 2019 using MEDLINE, EMBASE and Google Scholar. Inclusion criterion includes studies describing IBD phenotype in Latin Americans or in US Hispanics. Exclusion criterion includes prevalence or incidence studies not describing phenotype. A random effects model was chosen “a priori” for analysis of pooled proportions. A total of 46 studies were included from Latin America and 7 studies from the USA. The predominant IBD subtype in Latin America was UC with a more balanced UC:CD ratio noted in Puerto Rico (0.53) and Brazil (0.56). UC-related extensive colitis was more common in US Hispanics (0.64) than in Latin Americans (0.38), p<0.001. CD phenotype was similar between US Hispanics and Latin Americans. UC is the predominant IBD subtype in Latin America, with the exception of Puerto Rico and Brazil which demonstrate a more balanced UC:CD ratio. In UC, extensive colitis was more frequently seen in US Hispanics than in Latin Americans. CD phenotype was similar in both US Hispanics and Latin Americans.


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