Efficient thrust enhancement by modified pitching motion

2021 ◽  
Vol 933 ◽  
Author(s):  
Zaka Muhammad ◽  
Md. Mahbub Alam ◽  
Bernd R. Noack

Thrust and/or efficiency of a pitching foil (mimicking a tail of swimming fish) can be enhanced by tweaking the pitching waveform. The literature, however, show that non-sinusoidal pitching waveforms can enhance either thrust or efficiency but not both simultaneously. With the knowledge and inspiration from nature, we devised and implemented a novel asymmetrical sinusoidal pitching motion that is a combination of two sinusoidal motions having periods T1 and T2 for the forward and retract strokes, respectively. The motion is represented by period ratio $\mathrm{\mathbb{T}} = {T_1}/T$ , where T = (T1 + T2)/2, with $\mathrm{\mathbb{T}} > 1.00$ giving the forward strokes (from equilibrium to extreme position) slower than the retract strokes (from extreme to equilibrium position) and vice versa. The novel pitching motion enhances both thrust and efficiency for $\mathrm{\mathbb{T}} > 1.00$ . The enhancement results from the resonance between the shear-layer roll up and the increased speed of the foil. Four swimming regimes, namely normal swimming, undesirable, floating and ideal are discussed, based on instantaneous thrust and power. The results from the novel pitching motion display similarities with those from fish locomotion (e.g. fast start, steady swimming and braking). The $\mathrm{\mathbb{T}} > 1.00$ motion in the faster stroke has the same characteristics and results as the fast start of prey to escape from a predator while $\mathrm{\mathbb{T}} < 1.00$ imitates braking locomotion. While $\mathrm{\mathbb{T}} < 1.00$ enhances the wake deflection at high amplitude-based Strouhal numbers (StA = fA/U∞, where f and A are the frequency and peak-to-peak amplitude of the pitching, respectively, and U∞ is the freestream velocity), $\mathrm{\mathbb{T}} > 1.00$ improves the wake symmetry, suppressing the wake deflection. The wake characteristics including wake width, jet velocity and vortex structures are presented and connected with $S{t_d}( = fd/{U_\infty })$ , ${A^{\ast}}( = A/d)$ and $\mathrm{\mathbb{T}}$ , where d is the maximum thickness of the foil.

Author(s):  
S Kalmykov ◽  
O Polomarov ◽  
D Korobkin ◽  
J Otwinowski ◽  
J Power ◽  
...  

Compact accelerators of the future will require enormous accelerating gradients that can only be generated using high power laser beams. Two novel techniques of laser particle acceleration are discussed. The first scheme is based on a solid-state accelerating structure powered by a short pulse CO 2 laser. The planar structure consists of two SiC films, separated by a vacuum gap, grown on Si wafers. Particle acceleration takes place inside the gap by a surface electromagnetic wave excited at the vacuum/SiC interface. Laser coupling is accomplished through the properly designed Si grating. This structure can be inexpensively manufactured using standard microfabrication techniques and can support accelerating fields well in excess of 1 GeV m −1 without breakdown. The second scheme utilizes a laser beatwave to excite a high-amplitude plasma wave, which accelerates relativistic particles. The novel aspect of this technique is that it takes advantage of the nonlinear bi-stability of the relativistic plasma wave to drive it close to the wavebreaking.


2020 ◽  
Author(s):  
Jessie Gan ◽  
Zhao Zhihai ◽  
Yu Miao

AbstractMetastasis is widely accepted to be responsible for approximately 90% of all cancer deaths. Current research on metastasis prediction often centers on gene sequencing; however, these analyses must account for the complexity of gene regulation and rely on comprehensive datasets. To investigate the process from a simpler, non-genomic angle, some studies indicate differences in cell adhesion force, an important physical process in metastasizing cells. However, cell adhesion force methods tend to focus on cell population approaches and therefore have their drawbacks in cost or efficiency, rendering them impractical outside a research setting. In this work, we test a novel and inexpensive bead-pipette assay to investigate the adhesion forces of non-metastatic NIH3T3 cells and mutated RasV12 cells, a metastatic model cell line.Control cells and RasV12 cells were evaluated with wound healing, spreading area, and focal adhesion (FA) analysis assays. Then cells were tested by the novel bead-pipette assay, which uses a fibronectin-coated bead and a glass micropipette to measure cell adhesion force using Hooke’s law.The RasV12 cells had faster migration, polarized cell shape, and smaller FA area than control cells. The RasV12 cells also exerted higher adhesion forces than control cells and a potential force threshold was determined for distinguishing metastatic cells through a Receiver Operating Characteristic (ROC) curve. An ROC curve was computed for all other assays and the bead-pipette assay was shown to perform higher as a classifier than other assays.The RasV12 cells had increased metastatic potential compared to control. The novel bead-pipette assay showed potential as a classifier for determining metastasizing cells from non-metastatic cells. With further work, it may serve as a clinical diagnostic tool for cancer patients or as a testbed to be used in the development of anti-metastatic drugs.


Inventions ◽  
2018 ◽  
Vol 3 (4) ◽  
pp. 75 ◽  
Author(s):  
Gilbert Audira ◽  
Bonifasius Sampurna ◽  
Stevhen Juniardi ◽  
Sung-Tzu Liang ◽  
Yu-Heng Lai ◽  
...  

The measurement of multiple behavior endpoints in zebrafish can provide informative clues within neurobehavioral field. However, multiple behavior evaluations usually require complicated and costly instrumental settings. Here, we reported a versatile setting that applied ten acrylic tanks arranging into five vertical layers and two horizontal columns to perform multiple behavior assays simultaneously, such as the novel tank diving test, mirror-biting test, social interaction, shoaling, and predator escape assay. In total, ten behavioral performance were collected in a single video, and the XY coordination of fish locomotion can be tracked by using open source software of idTracker and ImageJ. We validated our setting by examining zebrafish behavioral changes after exposure to low dose ethanol (EtOH) for 96 h. Fish were observed staying longer time at bottom of the tank, less mirror biting interest, higher freezing time, less fear in predator test, and tight shoaling behaviors which indicated the anxiogenic effect was induced by low dosage exposure of EtOH in zebrafish. In conclusion, the setting in this study provided a simple, versatile and cost-effective way to assess multiple behavioral endpoints in zebrafish with high reliability and reproducibility for the first time.


2019 ◽  
Vol 43 (4) ◽  
pp. 21-25
Author(s):  
Y. V. Lekomtseva

Abstract Purpose of the study. The aim was to study in the patients with long-term consequences after cerebral contusion the intensity of spontaneous and H2O2-induced chemiluminescence in order to evaluate the early fast-flowing reactions caused by oxidative stress and associated with the formation of primary radicals such as free radical oxidations. Materials and Methods. Forty-two patients with long-term consequences after cerebral contusion were investigated (39,04 ± 12,84 years mean age; mean onset years 32,56 ± 6,4) where both spontaneous and H2O2-induced chemiluminescences were measured directly by HPLC-chemiluminescence assay. Results. The study have showed that sera of the investigated patients with long-term consequences after cerebral contusion have the increased H2O2-induced chemiluminescence associated with the high amplitude of «fast» burst and the tendency to increase of spontaneous chemiluminescence (p = 0,039 and p = 0,58, accordingly). Thus, the patients with long-term consequences after cerebral contusion showed the abnormal high kinetics of H2O2-induced chemiluminescence (p < 0,05). The statistically significant increase serum Н2О2-induced chemiluminescence intensity detected in examined patients (3085,6 ± 114,2 vs 669,1 ± 214,83 controls) have showed the development of certain oxidative stress processes in this category of patients associated with the increasing of primary free radical reactions and their activity were getting increased with the progression of the disease duration (p < 0,05). Conclusions. The study provides the novel data revealing the increased kinetics of H2O2-induced chemiluminescence in the patients with long-term consequences after cerebral contusion accompanied by the tendency to increase of spontaneous chemiluminescence that may play the certain pathogenetic role. Keywords: H2O2-induced chemiluminescence, long-term consequences after cerebral contusion, oxidative stress.


Author(s):  
R J Lawrence ◽  
G M O'Donoghue ◽  
P Kitterick ◽  
D E H Hartley

Abstract Background Mastoid surgery is an aerosol-generating procedure that involves the use of a high-speed drill, which produces a mixture of water, bone, blood and tissue that may contain the viable coronavirus disease 2019 pathogen. This potentially puts the surgeon and other operating theatre personnel at risk of acquiring the severe acute respiratory syndrome coronavirus-2 from contact with droplets or aerosols. The use of an additional drape designed to limit the spread of droplets and aerosols has been described; such drapes include the ‘Southampton Tent’ and ‘OtoTent’. Objectives To evaluate the use of a novel drape ‘tent’ that has advantages over established ‘tent’ designs in terms of having: (1) a CE marking; (2) no requirement for modification during assembly; and (3) no obstruction to the surgical visual field. Results and conclusion During mastoid surgery, the dispersion of macroscopic droplets and other particulate matter was confined within the novel drape ‘tent’. Use of this drape ‘tent’ had no adverse effects upon the surgeon's manual dexterity or efficiency, the view of the surgical field, or the sterility. Hence, our findings support its use during mastoid surgery in the coronavirus disease 2019 era.


2010 ◽  
Vol 34 (8) ◽  
pp. S33-S33
Author(s):  
Wenchao Ou ◽  
Haifeng Chen ◽  
Yun Zhong ◽  
Benrong Liu ◽  
Keji Chen

Sign in / Sign up

Export Citation Format

Share Document