Vitamin D status in Sri Lankans living in Sri Lanka and Norway

Vitamin D deficiency is common in non-Western immigrant groups living in Western countries. A comparison of vitamin D status in individuals who have emigrated and individuals who remain in their country of origin is needed in order to provide information about the effect of moving to northern latitudes. A total of 196 participants aged 30–60 years in a cross-sectional population-based study in Kandy, Sri Lanka (latitude 7° north) and 242 Sri Lankans aged 31–60 years participating in a cross-sectional population-based study in Oslo, Norway (latitude 60° north) were included in the analysis. All serum samples were analysed for serum 25-hydroxyvitamin D (s-25(OH)D) in the same laboratory. Sri Lankans living in Norway had substantially lower s-25(OH)D (mean 31·5 nmol/l) compared with those living in Sri Lanka (mean 54·2 nmol/l), and the prevalence of s-25(OH)D < 25 nmol/l was 9·3 times higher (95 % CI 4·4, 19·6) in Norway compared with Sri Lanka. In Sri Lanka there was a clear seasonal variation with the lowest s-25(OH)D levels in August–September and the highest levels in November–December. We conclude that vitamin D status among Sri Lankans living in Kandy, Sri Lanka was considerably higher than that among Sri Lankans living in Oslo, Norway. The low vitamin D status commonly observed in non-Western immigrant groups living at northern latitudes should not be regarded as normal levels for these groups. However, also in Sri Lanka we found a profound seasonal variation with the lowest levels in August and September after the Monsoon.

Download Full-text

Low Vitamin D Status in a Representative Sample of Youth From Québec, Canada

Clinical Chemistry ◽

10.1373/clinchem.2008.104158 ◽

2008 ◽

Vol 54 (8) ◽

pp. 1283-1289 ◽

Cited By ~ 49

Author(s):

Sean Mark ◽

Katherine Gray-Donald ◽

Edgard E Delvin ◽

Jennifer O'Loughlin ◽

Gilles Paradis ◽

...

Keyword(s):

Vitamin D ◽

Children And Adolescents ◽

Bone Growth ◽

Public Health Problem ◽

Population Based ◽

Vitamin D Status ◽

Cross Sectional ◽

Hydroxyvitamin D ◽

Canadian Youth ◽

25 Hydroxyvitamin D

Abstract Background: Adequate vitamin D status is important for bone growth and mineralization and has been implicated in the regulation of autoimmunity, metabolic function, and cancer prevention. There are no reports of population-based studies on the vitamin D status of Canadian youth, a population with mandatory fortification of foods. Methods: We measured plasma 25-hydroxyvitamin D [25(OH)D], the best indicator of vitamin D status, in a school-based cross-sectional sample of representative French Canadian youth (n = 1753) ages 9, 13, and 16 years living in Québec (latitude: 45°–48°N). Blood samples were collected from January to May 1999. We defined 25(OH)D deficiency as ≤27.5 nmol/L, hypovitaminosis as ≤37.5 nmol/L, and optimal as >75.0 nmol/L. Results: More than 93% of youth in each age and sex group had suboptimal 25(OH)D concentrations. The prevalence of 25(OH)D deficiency increased with age in both sexes (P < 0.0001). It was 2%, 3%, and 13% in 9-, 13-, and 16-year-old boys and 2%, 8%, and 10% in 9-, 13-, and 16-year-old girls. Girls with higher body mass index and girls from households with lower income had lower 25(OH)D concentrations. These effects were not observed in boys. Conclusions: Inadequate vitamin D status is a potentially serious public health problem among children and adolescents in Québec. Youth living at high latitudes in countries with and without mandatory fortification of vitamin D are likely at heightened risk of 25(OH)D deficiency. These results call for renewed efforts to ensure adequate vitamin D intake among growing children and adolescents.

Download Full-text

PO-0999 Suboptimal Vitamin D Status In A Population-based Study Of Asian Children: Prevalence And Relation To Allergic Diseases And Atopy

Archives of Disease in Childhood ◽

10.1136/archdischild-2014-307384.1617 ◽

2014 ◽

Vol 99 (Suppl 2) ◽

pp. A577.3-A577

Author(s):

TC Yao ◽

Y Tseng ◽

S Liao ◽

M Hua ◽

M Tsai ◽

...

Keyword(s):

Vitamin D ◽

Allergic Diseases ◽

Population Based ◽

Vitamin D Status ◽

Population Based Study ◽

Asian Children

Download Full-text

Stable Rates of Low Vitamin D Status Among Children Despite Increase in Testing: A Population-Based Study

The Journal of Pediatrics ◽

10.1016/j.jpeds.2021.07.037 ◽

2021 ◽

Author(s):

Alyssa A. Kerber ◽

Mitchell M. Pitlick ◽

Anna E. Kellund ◽

Amy L. Weaver ◽

Seema Kumar ◽

...

Keyword(s):

Vitamin D ◽

Population Based ◽

Vitamin D Status ◽

Population Based Study

Download Full-text

COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents

Nutrients ◽

10.3390/nu13051714 ◽

2021 ◽

Vol 13 (5) ◽

pp. 1714

Author(s):

Habiba AlSafar ◽

William B. Grant ◽

Rafiq Hijazi ◽

Maimunah Uddin ◽

Nawal Alkaabi ◽

...

Keyword(s):

Vitamin D ◽

United Arab Emirates ◽

Blood Levels ◽

Vitamin D Status ◽

Hospital Visit ◽

Serum Samples ◽

Hydroxyvitamin D ◽

Increased Risk ◽

Multiethnic Population ◽

25 Hydroxyvitamin D

Insufficient blood levels of the neurohormone vitamin D are associated with increased risk of COVID-19 severity and mortality. Despite the global rollout of vaccinations and promising preliminary results, the focus remains on additional preventive measures to manage COVID-19. Results conflict on vitamin D’s plausible role in preventing and treating COVID-19. We examined the relation between vitamin D status and COVID-19 severity and mortality among the multiethnic population of the United Arab Emirates. Our observational study used data for 522 participants who tested positive for SARS-CoV-2 at one of the main hospitals in Abu Dhabi and Dubai. Only 464 of those patients were included for data analysis. Demographic and clinical data were retrospectively analyzed. Serum samples immediately drawn at the first hospital visit were used to measure serum 25-hydroxyvitamin D [25(OH)D] concentrations through automated electrochemiluminescence. Levels < 12 ng/mL were significantly associated with higher risk of severe COVID-19 infection and of death. Age was the only other independent risk factor, whereas comorbidities and smoking did not contribute to the outcomes upon adjustment. Sex of patients was not an important predictor for severity or death. Our study is the first conducted in the UAE to measure 25(OH)D levels in SARS-CoV-2-positive patients and confirm the association of levels < 12 ng/mL with COVID-19 severity and mortality.

Download Full-text

Vitamin D Status and Seasonal Variation among Danish Children and Adults: A Descriptive Study

Nutrients ◽

10.3390/nu10111801 ◽

2018 ◽

Vol 10 (11) ◽

pp. 1801 ◽

Cited By ~ 20

Author(s):

Louise Hansen ◽

Anne Tjønneland ◽

Brian Køster ◽

Christine Brot ◽

Rikke Andersen ◽

...

Keyword(s):

Vitamin D ◽

Seasonal Variation ◽

Vitamin D Status ◽

Hydroxyvitamin D ◽

Supplement Use ◽

Wide Range ◽

Adults And Children ◽

25 Hydroxyvitamin D ◽

Vitamin D Supplement ◽

Very High

The aim of the present study was to describe vitamin D status and seasonal variation in the general Danish population. In this study, 3092 persons aged 2 to 69 years (2565 adults, 527 children) had blood drawn twice (spring and autumn) between 2012 and 2014. A sub-sample of participants had blood samples taken monthly over a year. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured by liquid chromatography mass spectrometry, and information on supplement use was assessed from questionnaires. Seasonal variations in 25(OH)D concentrations were evaluated graphically and descriptively, and status according to age, sex, and supplement use was described. It was found that 86% of both adults and children were vitamin D-sufficient in either spring and or/autumn; however, many had a spring concentration below 50 nmol/L. A wide range of 25(OH)D concentrations were found in spring and autumn, with very low and very high values in both seasons. Among adults, women in general had higher median 25(OH)D concentrations than men. Furthermore, vitamin D supplement use was substantial and affected the median concentrations markedly, more so during spring than autumn. Seasonal variation was thus found to be substantial, and bi-seasonal measurements are vital in order to capture the sizable fluctuations in vitamin D status in this Nordic population.

Download Full-text

Variation of circulating 25-Hydroxyvitamin D levels with life style in a cohort group in Sri Lanka

Nutrition & Food Science ◽

10.1108/nfs-06-2018-0168 ◽

2019 ◽

Vol 49 (4) ◽

pp. 506-516 ◽

Cited By ~ 3

Author(s):

Shirani Ranasinghe ◽

Thilak Jayalath ◽

Sampath Thennakoon ◽

Ranjith Jayasekara ◽

Ran Shiva ◽

...

Keyword(s):

Vitamin D ◽

Sri Lanka ◽

Feeding Habits ◽

Serum Vitamin ◽

Healthy Adults ◽

Vitamin D Status ◽

Content Type ◽

Hydroxyvitamin D ◽

Serum Vitamin D ◽

25 Hydroxyvitamin D

Purpose Purpose of this study is to measure the Vitamin D status of healthy adults and to correlate with their lifestyle and feeding habits. Plasma 25-Hydroxyvitamin D (25(OH)D) is the most common marker of vitamin D status of an individual. Deficiency of vitamin D is defined as the serum level less than 20 ng/mL and insufficiency as 30 ng/mL which can be prevented. Design/methodology/approach Vitamin D status of healthy adults (n = 82), both male and females between the age of 18 – 50 years who were attending to the National Transport Authority, Kandy, Sri Lanka from February to March 2016, was measured and correlated with their lifestyle, feeding habits, etc. Findings The mean total serum D (25(OH)D in this study was 40.15 ± 3.74 nmol/l with the mean value of 42.8 ± 28.8 and 37.5 ± 16.6 for women and men, respectively. The serum calcium levels of both female and male were around 8 mg/dl and the serum total protein was 6.5 and 7 g/dl in women and men, respectively. The serum Vitamin D, calcium and total protein were not statistically significantly different between the sexes. In this study, 84 per cent of the total subjects were normocalcemic, and there was no signiﬁcant relationship between vitamin D levels and their calcium levels. Research limitations/implications This study demonstrates that there was no statistically significant correlation between the serum vitamin D with age, serum calcium or total proteins. The majority of participants who had exposure to the sunlight more than 30 mins/day had sufficient level of vitamin D and less than 30 min/day exposure had deficiency of vitamin D. Daily intake of multivitamin influenced vitamin D status of the study group. Practical implications These findings will implicate the importance of cultural, feed and social habits for the nutritional status of an individual.and there are no reported studies on vitamin D status with reference to the variation of life style. Social implications It is very important to investigate the factors affecting to the vitamin D status of a population as such, vitamin D insufficiency or deficiency can be prevented. In Sri Lanka, the population is consisting with many ethnic groups, different ethnic groups may find some nutritional problems according to their main cultural habits. Originality/value The objectives of this study are to evaluate the Vitamin D status in a group of healthy adults between 20 and 50 years in both men and women and to find out the correlation of their vitamin D status with their lifestyle and feeding habits, etc.

Download Full-text

Association between 25-hydroxyvitamin D and inflammatory biomarker levels in a cross-sectional population-based study, São Paulo, Brazil

Nutrition Research ◽

10.1016/j.nutres.2015.10.006 ◽

2016 ◽

Vol 36 (1) ◽

pp. 1-8 ◽

Cited By ~ 15

Author(s):

Wysllenny N. de Souza ◽

Marina M. Norde ◽

Érica Oki ◽

Marcelo M. Rogero ◽

Dirce M.L. Marchioni ◽

...

Keyword(s):

Population Based ◽

Sao Paulo ◽

São Paulo ◽

Cross Sectional ◽

Population Based Study ◽

Inflammatory Biomarker ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D

Download Full-text

Vitamin D status of children in Kerala, southern India

Public Health Nutrition ◽

10.1017/s1368980018003622 ◽

2019 ◽

Vol 23 (7) ◽

pp. 1179-1183 ◽

Cited By ~ 1

Author(s):

Madhava Vijayakumar ◽

Vijayalakshmi Bhatia ◽

Biju George

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Sun Exposure ◽

Southern India ◽

Fish Diet ◽

Vitamin D Status ◽

Cross Sectional ◽

Dietary Recall ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D

AbstractObjectiveTo study plasma 25-hydroxyvitamin D (25(OH)D) status of children in Kerala, southern India, and its relationship with sociodemographic variables.DesignCross-sectional observational study.SettingTertiary government hospital.ParticipantsChildren (n 296) with trivial acute illness were enrolled. Sun exposure and Ca and vitamin D intakes (7 d dietary recall) were documented. Serum Ca, P, alkaline phosphatase, plasma 25(OH)D and parathyroid hormone (PTH) were measured.ResultsPrevalence of vitamin D deficiency (plasma 25(OH)D <30 nmol/l) was 11·1% (median, interquartile range (IQR): 52·6, 38·4–65·6 nmol/l). Children who ate fish daily had significantly higher plasma 25(OH)D than those who did not (median, IQR: 52·5, 40·8–68·9 v. 49·1, 36·2–60·7 nmol/l; P = 0·02). Those investigated in the months of March–May showed highest 25(OH)D v. those enrolled during other times (median, IQR: 58·7, 45·6–81·4 v. 45·5, 35·6–57·4 nmol/l; P <0·001). Plasma 25(OH)D correlated positively with serum P (r = 0·24, P <0·001) and Ca intake (r = 0·16, P 0·03), negatively with age (r = −0·13, P 0·03) and PTH (r = −0·22, P <0·001.). On linear regression, summer season (March–May), lower age, daily fish intake and higher Ca intake were independently associated with plasma 25(OH)D.ConclusionsPrevalence of vitamin D deficiency is low in Kerala. The natural fish diet of coastal Kerala and the latitude may be protective. Public health policy in India should take account of this geographical diversity.

Download Full-text

Vitamin D status in Greenland is influenced by diet and ethnicity: a population-based survey in an Arctic society in transition

British Journal Of Nutrition ◽

10.1017/s0007114512002097 ◽

2012 ◽

Vol 109 (5) ◽

pp. 928-935 ◽

Cited By ~ 22

Author(s):

Stig Andersen ◽

Peter Laurberg ◽

Bodil Hvingel ◽

Kent Kleinschmidt ◽

Lene Heickendorff ◽

...

Keyword(s):

Vitamin D ◽

Population Based ◽

The Arctic ◽

Vitamin D Status ◽

Hydroxyvitamin D ◽

Supplement Use ◽

Median Plasma ◽

Dietary Transition ◽

Societal Changes ◽

Item Scores

Vitamin D status as measured by plasma 25-hydroxyvitamin D (25(OH)D) is important to human health. Circumpolar people rely on dietary sources and societal changes in the Arctic are having profound dietary effects. The objective of the present study was to determine plasma 25(OH)D status and factors important to plasma 25(OH)D in populations in Greenland. Inuit and non-Inuit aged 50–69 years in the capital in West Greenland (latitude 64°15′N) and in a major town and remote settlements in East Greenland (latitude 65°35′N) were surveyed. Supplement use and lifestyle factors were determined by questionnaires. Inuit food scores were computed from a FFQ of seven traditional Inuit and seven imported food items. 25(OH)D2 and 25(OH)D3 levels were measured in the plasma. We invited 1 % of the population of Greenland, and 95 % participated. 25(OH)D3 contributed 99·7 % of total plasma 25(OH)D. Non-Inuit had the lowest median plasma 25(OH)D of 41 (25th–75th percentile 23–53) nmol/l compared with 64 (25th–75th percentile 51–81) nmol/l in Inuit (P< 0·001). Plasma 25(OH)D was below 20 and 50 nmol/l in 13·8 and 60·1 % of participants, respectively, with Inuit food item scores below 40 % (P< 0·001), and in 0·2 and 25·0 % of participants, respectively, with higher scores (P< 0·001). The Inuit diet was an important determinant of plasma 25(OH)D (P< 0·001) and its effect was modified by ethnicity (P= 0·005). Seal (P= 0·005) and whale (P= 0·015) were major contributors to plasma 25(OH)D. In conclusion, a decrease in the intake of the traditional Inuit diet was associated with a decrease in plasma 25(OH)D levels, which may be influenced by ethnicity. The risk of plasma 25(OH)D deficiency in Arctic populations rises with the dietary transition of societies in Greenland. Vitamin D intake and plasma 25(OH)D status should be monitored.

Download Full-text