In vitrotapeworm extract-induced proliferative responses of gut-associated lymphoid cells fromHymenolepis diminutainfected mice

1983 ◽  
Vol 57 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Dale D. Isaak
Keyword(s):  
Lymph Nodes ◽  
Immune Cells ◽  
Culture System ◽  
Lymphoid Cells ◽  
Hymenolepis Diminuta ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

AbstractThe development of lymphoid cells reactive to tapeworm-associated antigens during the course ofHymenolepis diminutarejection from mice was studied using anin vitrotapeworm extract (TWE)-induced cell proliferation culture system. Mice infected with three cysticercoids on day 0 developed three adult worms by day 7 but worms were rejected by day 21 post-infection. Concomitant with worm rejection was the development of TWE-sensitized lymphoid cells which responded by proliferation when stimulatedin vitrowith TWE. Sensitized cells were detected in gut-associated mesenteric lymph nodes but were not detected in spleen, axillary lymph nodes, or peyer's patches of infected mice, or in lymphoid organs of non-infected mice. These studies suggest that rejection ofH. diminutafrom mice is associated with the activities of gut-associated, tapeworm antigen-sensitized immune cells localized in the mesenteric lymph nodes.

Breast Tumors: Immunoglobulins in Axillary Lymph Nodes

1986 ◽  
Vol 72 (6) ◽  
pp. 575-579 ◽  
Author(s):  
Mariano Urdiales-Viedma ◽  
Francisco Nogales-Fernandez ◽  
Sebastian Martos-Padilla ◽  
Emilio Sanchez-Cantalejo
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Breast Tumors ◽  
Lymphoid Cells ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Lymphoid Follicles ◽  
Node Metastases ◽  
High Histologic Grade

The immnuohistochemical determination of immunoglobulins IgA, IgG and IgM in axillary lymph nodes from 50 unselected breast ductal carcinomas disclosed that lymph nodes with IgG-positive lymphoid follicles and/or metastasized lymph nodes with IgM-positive lymphoid cells are statistically related to breast tumors with a high histologic grade and more than 3 lymph node metastases.

The structure of the thymus and mesenteric lymph nodes of newborn rats as a result of the prenatal influence of ethanol

2015 ◽  
Vol 6 (4) ◽  
pp. 51-55 ◽  
Author(s):  
Petr Vladimirovich Pugach ◽  
Sergey Vladimirovich Kruglov ◽  
Natalia Rafailovna Karelina ◽  
Dmitriy Vitalievich Breusenko ◽  
Stepan Yurevich Bazhin ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Morphological Changes ◽  
Alcohol Intoxication ◽  
Sole Source ◽  
Structural Features ◽  
Lymphoid Cells ◽  
Newborn Rats ◽  
Mesenteric Lymph Nodes ◽  
White Rats ◽  
Mesenteric Lymph

The present study was undertaken to examine the structural features of the thymus and cranial mesenteric lymph nodes of newborn rats that have occurred as a result of antenatal alcohol intoxication. We used a set of morphometric, anatomical and histological methods. A study of the cranial mesenteric lymph nodes performed on 45 newborn rats born to 18 female mongrel white rats seven months of age. The studies were conducted in compliance with the order of the Ministry of Health of the USSR N 755 from 12.08.1977 and the order of the Ministry of Higher and Secondary Special Education of the USSR from 13.11.1984, "On the rules of work with experimental animals". Females, on which was received investigated offspring exposed to 15 % ethanol as the sole source of fluid for 1 week, one and three months before pregnancy, during pregnancy and after its completion. It is shown that depending on the duration of pregravid exposure to ethanol occur progredient changes in the structure of the thymus and cranial mesenteric lymph nodes. In the thymus, as well as in the lymph nodes, decreases the number of lymphoid cells and stromal elements content increases. In lymph nodes there are significant changes in the structure of the sinus system. The severity of the identified morphological changes due to the duration of the effects of alcohol on the system "mother-placenta-fetus”.

scholarly journals Fulminant Liver Failure with Necrotizing Foci in the Liver, Spleen and Lymph Nodes in Celiac Disease Due to Malignant Lymphoma

1996 ◽  
Vol 10 (4) ◽  
pp. 225-229 ◽  
Author(s):  
Hugh James Freeman
Keyword(s):  
Celiac Disease ◽  
T Cell ◽  
Lymph Nodes ◽  
Liver Failure ◽  
Cell Receptor ◽  
Lymphoid Cells ◽  
Mesenteric Lymph Nodes ◽  
Rare Type ◽  
Mesenteric Lymph ◽  
Spleen And Lymph Nodes

A 65-year-old female with celiac disease developed cholestatic jaundice and fatal liver failure. Investigations revealed widespread necrotic foci in the liver, spleen and mesenteric lymph nodes, changes reminiscent of the mesenteric lymph node cavitation syndrome, which is known to complicate celiac disease. In addition, malignant lymphoid cells were present infiltrating hepatic sinusoids, lymph nodes and spleen. These features are typical of hepatosplenic lymphoma, a rare type of peripheral T cell lymphoma with T cell receptor rearrangement. Lymphorecticular malignancy complicating celiac disease may present with fulminant liver disease.

STUDY OF LYMPHOCTYE INTERACTION IN HUMAN MESENTERIC LYMPH NODES IN VITRO

1984 ◽  
Vol 62 (5) ◽  
pp. 531-537
Author(s):  
AW Cripps ◽  
RL Clancy ◽  
H Chipchase ◽  
EJ Hennessy
Keyword(s):  
Lymph Nodes ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

scholarly journals Analysis of IL-2 Production in Hookworm Infected Hamsters Using Generated Polyclonal Antibodies

2012 ◽  
Vol 56 (1) ◽  
pp. 37-42
Author(s):  
Ewa Długosz ◽  
Jarosław Cendrowski ◽  
Piotr Bąska ◽  
Anna Siwińska ◽  
Halina Wędrychowicz ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Lymph Nodes ◽  
Cell Cultures ◽  
Polyclonal Antibodies ◽  
Mesenteric Lymph Nodes ◽  
Ancylostoma Ceylanicum ◽  
Specific Antibodies ◽  
Mesenteric Lymph ◽  
Race Pcr

Abstract The aim of the study was cloning and analysis of the entire coding sequence of hamster IL-2 by the method of RACE-PCR, its expression in Escherichia coli cells, and production of IL-2 specific antibodies. These antibodies were used to determine in vitro IL-2 production by cells derived from the spleen and mesenteric lymph nodes of Ancylostoma ceylanicum infected hamsters. The highest concentration of IL-2 was noted in supernatants from cell cultures coming from the oldest, most resistant hamsters.

scholarly journals CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Emma C. Mackley ◽  
Stephanie Houston ◽  
Clare L. Marriott ◽  
Emily E. Halford ◽  
Beth Lucas ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Lymphoid Cells ◽  
Intestinal Cells ◽  
Lymphoid Tissues ◽  
Mesenteric Lymph Nodes ◽  
Cell Responses ◽  
Mesenteric Lymph ◽  
Peripheral Lymph ◽  
Group 3 ◽  
Draining Lymph Nodes

Abstract Presentation of peptide:MHCII by RORγ-expressing group 3 innate lymphoid cells (ILC3s), which are enriched within gut tissue, is required for control of CD4 T-cell responses to commensal bacteria. It is not known whether ILC populations migrate from their mucosal and peripheral sites to local draining secondary lymphoid tissues. Here we demonstrate that ILC3s reside within the interfollicular areas of mucosal draining lymph nodes, forming a distinct microenvironment not observed in peripheral lymph nodes. By photoconverting intestinal cells in Kaede mice we reveal constitutive trafficking of ILCs from the intestine to the draining mesenteric lymph nodes, which specifically for the LTi-like ILC3s was CCR7-dependent. Thus, ILC populations traffic to draining lymph nodes using different mechanisms.

Cortical Morphologic Features of Axillary Lymph Nodes as a Predictor of Metastasis in Breast Cancer: In Vitro Sonographic Study

2008 ◽  
Vol 191 (3) ◽  
pp. 646-652 ◽  
Author(s):  
Deepak G. Bedi ◽  
Rajesh Krishnamurthy ◽  
Savitri Krishnamurthy ◽  
Beth S. Edeiken ◽  
Huong Le-Petross ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph

scholarly journals Evaluation of sonographic detectability of different markers within an in vitro simulation model of the axilla

2021 ◽  
Author(s):  
Selin Guergan ◽  
Uta Hoopmann ◽  
Carmen Roehm ◽  
Bettina Boeer ◽  
Regina Fugunt ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Real Life ◽  
Spherical Shape ◽  
Limiting Factors ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Fatty Tissue ◽  
Vitro Model

Abstract Purpose Clip-marking of axillary lymph nodes with initial biopsy-confirmed metastasis is required for targeted axillary dissection (TAD), which includes sentinel lymph node dissection (SLND) and selective localization and removal of the clipped targeted lymph node. There have been several studies which examined the feasibility of TAD in routine clinical use. In this context, the optimal clip visualisation was noted as one of the crucial limiting factors. We, therefore, evaluated the sonographic detectability of 10 different commercially available markers within an in vitro model simulating the anatomical composition of the axilla. Methods In this standardised model consisting of porcine fat with 30 mm thickness, the visibility of a total of ten markers was analysed in all 3 planes (parallel, diagonal, orthograde) with wire guidance and then classified into either “visibility good”, “visibility moderate” or “visibility poor” with regard to the alignment of the transducer. Additionally, “real-life conditions” were simulated, in which the markers were searched without any wires guidance. Results It was observed that, while not all markers are detectable in fatty tissue, markers with spherical shape (non-embedded Inconel or Nitinol) or rectangular-shaped Titanium markers with embedded material have a clear advantage. 3D-shaped markers can always be detected in all three axes, which is of particular importance in the axilla with its pyramid shape and fatty tissue. Conclusion The shape and the embedding of the material play a crucial role for visibility and efficacy of the marker, as reliable marking of suspicious and pathological axillary lymph nodes is essential for TAD.

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