Aberrant global and local dynamic properties in schizophrenia with instantaneous phase method based on Hilbert transform

2021 ◽  
pp. 1-11
Author(s):  
Dan Sheng ◽  
Weidan Pu ◽  
Zeqiang Linli ◽  
Guo-Liang Tian ◽  
Shuixia Guo ◽  
...  

Abstract Background Emerging functional imaging studies suggest that schizophrenia is associated with aberrant spatiotemporal interaction which may result in aberrant global and local dynamic properties. Methods We investigated the dynamic functional connectivity (FC) by using instantaneous phase method based on Hilbert transform to detect abnormal spatiotemporal interaction in schizophrenia. Based on resting-state functional magnetic resonance imaging, two independent datasets were included, with 114 subjects from COBRE [51 schizophrenia patients (SZ) and 63 healthy controls (HCs)] and 96 from OpenfMRI (36 SZ and 60 HCs). Phase differences and instantaneous coupling matrices were firstly calculated at all time points by extracting instantaneous parameters. Global [global synchrony and intertemporal closeness (ITC)] and local dynamic features [strength of FC (sFC) and variability of FC (vFC)] were compared between two groups. Support vector machine (SVM) was used to estimate the ability to discriminate two groups by using all aberrant features. Results We found SZ had lower global synchrony and ITC than HCs on both datasets. Furthermore, SZ had a significant decrease in sFC but an increase in vFC, which were mainly located at prefrontal cortex, anterior cingulate cortex, temporal cortex and visual cortex or temporal cortex and hippocampus, forming significant dynamic subnetworks. SVM analysis revealed a high degree of balanced accuracy (85.75%) on the basis of all aberrant dynamic features. Conclusions SZ has worse overall spatiotemporal stability and extensive FC subnetwork lesions compared to HCs, which to some extent elucidates the pathophysiological mechanism of schizophrenia, providing insight into time-variation properties of patients with other mental illnesses.

Electronics ◽  
2021 ◽  
Vol 10 (14) ◽  
pp. 1694
Author(s):  
Mathew Ashik ◽  
A. Jyothish ◽  
S. Anandaram ◽  
P. Vinod ◽  
Francesco Mercaldo ◽  
...  

Malware is one of the most significant threats in today’s computing world since the number of websites distributing malware is increasing at a rapid rate. Malware analysis and prevention methods are increasingly becoming necessary for computer systems connected to the Internet. This software exploits the system’s vulnerabilities to steal valuable information without the user’s knowledge, and stealthily send it to remote servers controlled by attackers. Traditionally, anti-malware products use signatures for detecting known malware. However, the signature-based method does not scale in detecting obfuscated and packed malware. Considering that the cause of a problem is often best understood by studying the structural aspects of a program like the mnemonics, instruction opcode, API Call, etc. In this paper, we investigate the relevance of the features of unpacked malicious and benign executables like mnemonics, instruction opcodes, and API to identify a feature that classifies the executable. Prominent features are extracted using Minimum Redundancy and Maximum Relevance (mRMR) and Analysis of Variance (ANOVA). Experiments were conducted on four datasets using machine learning and deep learning approaches such as Support Vector Machine (SVM), Naïve Bayes, J48, Random Forest (RF), and XGBoost. In addition, we also evaluate the performance of the collection of deep neural networks like Deep Dense network, One-Dimensional Convolutional Neural Network (1D-CNN), and CNN-LSTM in classifying unknown samples, and we observed promising results using APIs and system calls. On combining APIs/system calls with static features, a marginal performance improvement was attained comparing models trained only on dynamic features. Moreover, to improve accuracy, we implemented our solution using distinct deep learning methods and demonstrated a fine-tuned deep neural network that resulted in an F1-score of 99.1% and 98.48% on Dataset-2 and Dataset-3, respectively.


Geophysics ◽  
2016 ◽  
Vol 81 (2) ◽  
pp. V141-V150 ◽  
Author(s):  
Emanuele Forte ◽  
Matteo Dossi ◽  
Michele Pipan ◽  
Anna Del Ben

We have applied an attribute-based autopicking algorithm to reflection seismics with the aim of reducing the influence of the user’s subjectivity on the picking results and making the interpretation faster with respect to manual and semiautomated techniques. Our picking procedure uses the cosine of the instantaneous phase to automatically detect and mark as a horizon any recorded event characterized by lateral phase continuity. A patching procedure, which exploits horizon parallelism, can be used to connect consecutive horizons marking the same event but separated by noise-related gaps. The picking process marks all coherent events regardless of their reflection strength; therefore, a large number of independent horizons can be constructed. To facilitate interpretation, horizons marking different phases of the same reflection can be automatically grouped together and specific horizons from each reflection can be selected using different possible methods. In the phase method, the algorithm reconstructs the reflected wavelets by averaging the cosine of the instantaneous phase along each horizon. The resulting wavelets are then locally analyzed and confronted through crosscorrelation, allowing the recognition and selection of specific reflection phases. In case the reflected wavelets cannot be recovered due to shape-altering processing or a low signal-to-noise ratio, the energy method uses the reflection strength to group together subparallel horizons within the same energy package and to select those satisfying either energy or arrival time criteria. These methods can be applied automatically to all the picked horizons or to horizons individually selected by the interpreter for specific analysis. We show examples of application to 2D reflection seismic data sets in complex geologic and stratigraphic conditions, critically reviewing the performance of the whole process.


2017 ◽  
Author(s):  
Raúl Hernández-Pérez ◽  
Luis Concha ◽  
Laura V. Cuaya

AbstractDogs can interpret emotional human faces (especially the ones expressing happiness), yet the cerebral correlates of this process are unknown. Using functional magnetic resonance imaging (fMRI) we studied eight awake and unrestrained dogs. In Experiment 1 dogs observed happy and neutral human faces, and found increased brain activity when viewing happy human faces in temporal cortex and caudate. In Experiment 2 the dogs were presented with human faces expressing happiness, anger, fear, or sadness. Using the resulting cluster from Experiment 1 we trained a linear support vector machine classifier to discriminate between pairs of emotions and found that it could only discriminate between happiness and the other emotions. Finally, evaluation of the whole-brain fMRI time courses through a similar classifier allowed us to predict the emotion being observed by the dogs. Our results show that human emotions are specifically represented in dogs’ brains, highlighting their importance for inter-species communication.


2014 ◽  
Vol 519-520 ◽  
pp. 644-650
Author(s):  
Mian Shui Yu ◽  
Yu Xie ◽  
Xiao Meng Xie

Age classification based on facial images is attracting wide attention with its broad application to human-computer interaction (HCI). Since human senescence is a tremendously complex process, age classification is still a highly challenging issue. In our study, Local Directional Pattern (LDP) and Gabor wavelet transform were used to extract global and local facial features, respectively, that were fused based on information fusion theory. The Principal Component Analysis (PCA) method was used for dimensionality reduction of the fused features, to obtain a lower-dimensional age characteristic vector. A Support Vector Machine (SVM) multi-class classifier with Error Correcting Output Codes (ECOC) was proposed in the paper. This was aimed at multi-class classification problems, such as age classification. Experiments on a public FG-NET age database proved the efficiency of our method.


2019 ◽  
Vol 9 (15) ◽  
pp. 3130 ◽  
Author(s):  
Navarro ◽  
Perez

Many applications in image analysis require the accurate classification of complex patterns including both color and texture, e.g., in content image retrieval, biometrics, and the inspection of fabrics, wood, steel, ceramics, and fruits, among others. A new method for pattern classification using both color and texture information is proposed in this paper. The proposed method includes the following steps: division of each image into global and local samples, texture and color feature extraction from samples using a Haralick statistics and binary quaternion-moment-preserving method, a classification stage using support vector machine, and a final stage of post-processing employing a bagging ensemble. One of the main contributions of this method is the image partition, allowing image representation into global and local features. This partition captures most of the information present in the image for colored texture classification allowing improved results. The proposed method was tested on four databases extensively used in color–texture classification: the Brodatz, VisTex, Outex, and KTH-TIPS2b databases, yielding correct classification rates of 97.63%, 97.13%, 90.78%, and 92.90%, respectively. The use of the post-processing stage improved those results to 99.88%, 100%, 98.97%, and 95.75%, respectively. We compared our results to the best previously published results on the same databases finding significant improvements in all cases.


2015 ◽  
Vol 11 (6) ◽  
pp. 49 ◽  
Author(s):  
Dong Huang ◽  
Jian Gao

With the development of pen-based mobile device, on-line signature verification is gradually becoming a kind of important biometrics verification. This thesis proposes a method of verification of on-line handwritten signatures using both Support Vector Data Description (SVM) and Genetic Algorithm (GA). A 27-parameter feature set including shape and dynamic features is extracted from the on-line signatures data. The genuine signatures of each subject are treated as target data to train the SVM classifier. As a kernel based one-class classifier, SVM can accurately describe the feature distribution of the genuine signatures and detect the forgeries. To improving the performance of the authentication method, genetic algorithm (GA) is used to optimise classifier parameters and feature subset selection. Signature data form the SVC2013 database is used to carry out verification experiments. The proposed method can achieve an average Equal Error Rate (EER) of 4.93% of the skill forgery database.


2003 ◽  
Vol 36 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Sara Romer ◽  
Claus Urban ◽  
Vladimir Lobaskin ◽  
Frank Scheffold ◽  
Anna Stradner ◽  
...  

A new sample environment has been developed in order to perform light and small-angle neutron scattering (SANS) simultaneously on colloidal systems. The combination of SANS and diffusing wave spectroscopy (DWS) is of particular use in the high-concentration regime. DWS provides information on the local dynamic properties of the individual particles, whereas SANS gives access to the structural properties on similar length scales. The combination of both methods thus allows one to obtain structural and dynamic information over a very large range of length and time scales. Using this new setup, the onset of aggregation and the sol–gel transition in concentrated destabilized polystyrene sphere suspensions have been investigated. At the gel point, a dramatic change of the particle dynamics from diffusion to a subdiffusive arrested motion is observed. However, while the DWS measurements indicate that dramatic changes in the local dynamics occur over a long period, the SANS pattern quickly reaches its final appearance. The SANS experiments thus indicate that a fluid-like structure is arrested in the course of the gel formation. The data are found to be in good qualitative agreement with computer simulations.


2002 ◽  
Vol 82 (2) ◽  
pp. 133-141 ◽  
Author(s):  
J. L. Feldman ◽  
C. S. Hellberg ◽  
G. Viliani ◽  
W. Garber ◽  
F. M. Tangerman

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