Antimicrobial resistance in commensalEscherichia coliin veal calves is associated with antimicrobial drug use

2013 ◽  
Vol 142 (9) ◽  
pp. 1893-1904 ◽  
Author(s):  
A. B. BOSMAN ◽  
J. A. WAGENAAR ◽  
J. A. STEGEMAN ◽  
J. C. M. VERNOOIJ ◽  
D. J. MEVIUS
Keyword(s):  
Antimicrobial Resistance ◽  
Drug Use ◽  
Odds Ratio ◽  
Farm Management ◽  
Antimicrobial Drug ◽  
Production Cycle ◽  
Drug Usage ◽  
E Coli ◽  
Veal Calves ◽  
Pooled Sample

SUMMARYThe aim of this study was to determine the association between farm management factors, including antimicrobial drug usage, and resistance in commensalEscherichia coliisolates from the faeces of white veal calves. NinetyE. coliisolates from one pooled sample per farm (n = 48) were tested for their phenotypical resistance against amoxicillin, tetracycline, cefotaxime, ciprofloxacin and trimethoprim/sulfamethoxazole (TMP/SMX). Logistic regression analysis revealed the following risk factors (P < 0·05); farmer wearing the same work clothes for several days [ciprofloxacin, odds ratio (OR) 2·6; tetracycline, OR 2·4], administration of trimethoprim-sulfonamide combinations (TMP/SMX, OR 3·0; amoxicillin, OR 3·1; tetracycline, OR 2·6), ⩾0·3 animal daily dosage per production cycle (ADD/pc), quinolones (ciprofloxacin, OR 2·8), ⩾1·3 ADD/pc, penicillins (ciprofloxacin, OR 3·3; tetracycline, OR 3·4), 20–40 ADD/pc, tetracyclines (tetracycline, OR 3·2) and >40 ADD/pc, tetracyclines (tetracycline, OR 13·1; amoxicillin, OR 6·5). In this study antimicrobial resistance in commensalE. coliwas mainly associated with antimicrobial drug use.

Antimicrobial Drug Use and Antimicrobial Resistance in Enteric Bacteria Among Cattle from Alberta Feedlots

2010 ◽  
Vol 7 (4) ◽  
pp. 449-457 ◽  
Author(s):  
Sangeeta Rao ◽  
Joyce Van Donkersgoed ◽  
Valerie Bohaychuk ◽  
Thomas Besser ◽  
Xin-Ming Song ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Drug Use ◽  
Enteric Bacteria ◽  
Antimicrobial Drug

scholarly journals Monitoring antimicrobial resistance trends in commensal Escherichia coli from livestock, the Netherlands, 1998 to 2016

2019 ◽  
Vol 24 (25) ◽  
Author(s):  
Ayla Hesp ◽  
Kees Veldman ◽  
Jeanet van der Goot ◽  
Dik Mevius ◽  
Gerdien van Schaik
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Resistance ◽  
Monitoring Data ◽  
Resistant Isolate ◽  
Similar Data ◽  
Explanatory Variables ◽  
E Coli ◽  
Veal Calves ◽  
Before And After ◽  
Using Data

Background Monitoring of antimicrobial resistance (AMR) in animals is essential for public health surveillance. To enhance interpretation of monitoring data, evaluation and optimisation of AMR trend analysis is needed. Aims To quantify and evaluate trends in AMR in commensal Escherichia coli, using data from the Dutch national AMR monitoring programme in livestock (1998–2016). Methods Faecal samples were collected at slaughter from broilers, pigs and veal calves. Minimum inhibitory concentration values were obtained by broth microdilution for E. coli for 15 antimicrobials of eight antimicrobial classes. A Poisson regression model was applied to resistant isolate counts, with explanatory variables representing time before and after 2009 (reference year); for veal calves, sampling changed from 2012 represented by an extra explanatory variable. Results Resistant counts increased significantly from 1998-2009 in broilers and pigs, except for tetracyclines and sulfamethoxazole in broilers and chloramphenicol and aminoglycosides in pigs. Since 2009, resistant counts decreased for all antimicrobials in broilers and for all but the phenicols in pigs. In veal calves, for most antimicrobials no significant decrease in resistant counts could be determined for 2009–16, except for sulfamethoxazole and nalidixic acid. Within animal species, antimicrobial-specific trends were similar. Conclusions Using Dutch monitoring data from 1998-2016, this study quantified AMR trends in broilers and slaughter pigs and showed significant trend changes in the reference year 2009. We showed that monitoring in commensal E. coli is useful to quantify trends and detect trend changes in AMR. This model is applicable to similar data from other European countries.

scholarly journals Swedish high-school pupils’ attitudes towards drugs in relation to drug usage, impulsiveness and other risk factors

2014 ◽  
Author(s):  
Fariba Mousavi ◽  
Danilo Garcia ◽  
Alexander Jimmefors ◽  
Trevor Archer ◽  
Béatrice M Ewalds-Kvist
Keyword(s):  
Risk Factors ◽  
High School ◽  
Gender Differences ◽  
Drug Use ◽  
Odds Ratio ◽  
Drug Users ◽  
Individual Characteristics ◽  
Drug Usage ◽  
Positive Attitudes ◽  
And Gender

Background: Illicit drug use influences people’s lives and elicits unwanted here is an increase in young people’s drug use in Sweden. This study aimed to investigate Swedish high-school pupils’ attitudes, impulsiveness and gender differences linked to drug use. Also risk and protective factors relative to drug use were a focus of interest. Method: High school pupils (n = 146) aged 17- 21 years, responded to the Adolescent Health and Development Inventory, Barratt Impulsiveness Scale and Knowledge, and the Attitudes and Beliefs. Direct logistic, multiple regression analyses, and Multivariate Analysis of Variance were used to analyse the data. Results: Positive Attitudes towards drugs was predicted by risk factors (odds ratio = 37.31) and gender (odds ratio = .32). Risk factors (odds ratio = 46.89), positive attitudes towards drugs (odds ratio = 4.63), and impulsiveness (odds ratio = 1.11) predicted drug usage. Risk factors dimensions Family, Friends and Individual Characteristic were positively related to impulsiveness among drug users. Moreover, although males reported using drugs to a greater extent, but female expressed more positive attitude towards drugs and even reported more impulsiveness than male students. Conclusion: This study reinforces the idea that research must focus on gender differences relative to pro-drug attitudes along with testing for differences in the predictors of girls’ and boys’ delinquency and impulsiveness. Positive attitudes towards drugs among adolescents seem to be part of a vicious circle including risk factors, such as friendly drug environments (e.g., friends who use drugs) and unsupportive family environments, individual characteristics, and impulsiveness.

scholarly journals Antimicrobial resistance prevalence in commensal Escherichia coli from broilers, fattening turkeys, fattening pigs and veal calves in European countries and association with antimicrobial usage at country level

2020 ◽  
Vol 69 (4) ◽  
pp. 537-547 ◽  
Author(s):  
Daniela Ceccarelli ◽  
Ayla Hesp ◽  
Jeanet van der Goot ◽  
Philip Joosten ◽  
Steven Sarrazin ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Resistance ◽  
Type Species ◽  
European Countries ◽  
Content Type ◽  
E Coli ◽  
Veal Calves ◽  
Link Type ◽  
Country Level ◽  
Fattening Pigs

The aim of this article is to report on antimicrobial resistance (AMR) in commensal Escherichia coli from livestock from several European countries. The relationships with antimicrobial usage (AMU) at country level and harmonized indicators to cover the most relevant AMR aspects for human health in animal production were also investigated. E. coli were isolated in faeces from broilers and fattening pigs (from nine countries), and fattening turkeys and veal calves (from three countries) and screened against a fixed antimicrobial panel. AMU data were collected at farm and average treatment incidences stratified by antimicrobial class, country and livestock species were calculated. Associations between AMR and AMU at country level were analysed. Independent of animal species, the highest resistance was observed for ampicillin, sulphamethoxazole, tetracycline and trimethoprim. E. coli from broilers showed the highest resistance level for (fluoro)quinolones, and multidrug resistance peaked in broilers and fattening turkeys. Colistin resistance was observed at very low levels with the exception of fattening turkeys. High resistance to third- and fourth-generation cephalosporins was detected in broilers and fattening turkeys. The lowest levels of resistance were for meropenem, azithromycin and tigecycline (<1 %). Significant correlations between resistance and usage at country level were detected in broilers for polymyxins and aminoglycosides, and in fattening pigs for cephalosporins, amphenicols, fluoroquinolones and polymyxins. None of the correlations observed between AMR and AMU were statistically significant for fattening turkey and veal calves. The strength of the analysis performed here is the correlation of aggregated data from the same farms at country level for both AMU and AMR within antimicrobial classes.

scholarly journals Antimicrobial resistance prevalence of pathogenic and commensal Escherichia coli in food-producing animals in Belgium

2014 ◽  
Vol 83 (5) ◽  
pp. 225-233 ◽  
Author(s):  
I. Chantziaras ◽  
J. Dewulf ◽  
F. Boyen ◽  
B. Callens ◽  
P. Butaye
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Resistance ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Susceptibility Testing ◽  
Commensal Bacteria ◽  
The Other ◽  
E Coli ◽  
Veal Calves ◽  
Veal Calf

In this article, detailed studies on antimicrobial resistance to commensal E. coli (in pigs, meatproducing bovines, broiler chickens and veal calves) and pathogenic E. coli (in pigs and bovines) in Belgium are presented for 2011. Broiler chicken and veal calf isolates of commensal E. coli demonstrated higher antimicrobial resistance prevalence than isolates from pigs and bovines. Fifty percent of E. coli isolates from broiler chickens were resistant to at least five antimicrobials, whereas sixty-one percent of bovine E. coli isolates were susceptible to all antimicrobials tested. On the other hand, bovine pathogenic E. coli isolates showed an extended resistance profile with more than half of the isolates being resistant to ten or more antimicrobials. The results are not significantly different from the results from previously published studies on commensal bacteria in pigs in Belgium, although different methodologies of sampling and susceptibility testing were used.

scholarly journals Swedish high-school pupils’ attitudes towards drugs in relation to drug usage, impulsiveness and other risk factors

2014 ◽  
Author(s):  
Fariba Mousavi ◽  
Danilo Garcia ◽  
Alexander Jimmefors ◽  
Trevor Archer ◽  
Béatrice M Ewalds-Kvist
Keyword(s):  
Risk Factors ◽  
High School ◽  
Gender Differences ◽  
Drug Use ◽  
Odds Ratio ◽  
Drug Users ◽  
Individual Characteristics ◽  
Drug Usage ◽  
Positive Attitudes ◽  
And Gender

Background: Illicit drug use influences people’s lives and elicits unwanted here is an increase in young people’s drug use in Sweden. This study aimed to investigate Swedish high-school pupils’ attitudes, impulsiveness and gender differences linked to drug use. Also risk and protective factors relative to drug use were a focus of interest. Method: High school pupils (n = 146) aged 17- 21 years, responded to the Adolescent Health and Development Inventory, Barratt Impulsiveness Scale and Knowledge, and the Attitudes and Beliefs. Direct logistic, multiple regression analyses, and Multivariate Analysis of Variance were used to analyse the data. Results: Positive Attitudes towards drugs was predicted by risk factors (odds ratio = 37.31) and gender (odds ratio = .32). Risk factors (odds ratio = 46.89), positive attitudes towards drugs (odds ratio = 4.63), and impulsiveness (odds ratio = 1.11) predicted drug usage. Risk factors dimensions Family, Friends and Individual Characteristic were positively related to impulsiveness among drug users. Moreover, although males reported using drugs to a greater extent, but female expressed more positive attitude towards drugs and even reported more impulsiveness than male students. Conclusion: This study reinforces the idea that research must focus on gender differences relative to pro-drug attitudes along with testing for differences in the predictors of girls’ and boys’ delinquency and impulsiveness. Positive attitudes towards drugs among adolescents seem to be part of a vicious circle including risk factors, such as friendly drug environments (e.g., friends who use drugs) and unsupportive family environments, individual characteristics, and impulsiveness.

Antimicrobial resistance patterns and risk factors for cloacal Escherichia coli in chickens in central Tanzania

2021 ◽  
Vol 36 (1) ◽  
pp. 15-22
Author(s):  
C.A. Newberry ◽  
J.K. Lane ◽  
B.A. Byrne ◽  
M. Mwanzalila ◽  
T. Hamza ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Risk Factor ◽  
Antimicrobial Resistance ◽  
Significant Risk ◽  
Antimicrobial Drug ◽  
Educational Outreach ◽  
Diffusion Method ◽  
Flock Size ◽  
Antimicrobial Drugs ◽  
E Coli

Antimicrobial resistance is a serious and escalating threat to global health. This study established a baseline antimicrobial resistance profile and prevalence for cloacal Escherichia coli in chickens in central Tanzania. Animal husbandry practices, flock size, and chicken breed were recorded for risk factor evaluation to elucidate potential drivers of resistance across populations. Cloacal samples were collected from poultry in Iringa, Tanzania, and E. coli isolates cultured were then tested for susceptibility to seven medically important antimicrobial drugs: ampicillin, amoxicillin-clavulanate, cefoxitin, enrofloxacin, gentamicin, sulfamethoxazole-trimethoprim, and tetracycline using the Kirby-Bauer disk diffusion method. Over 94% of the 59 E. coli isolates tested were resistant to at least one antimicrobial drug, and over 61% of isolates were resistant to three or more classes of antimicrobial drugs. The highest prevalence of resistance found was to tetracycline and sulfamethoxazole-trimethoprim (88% and 86%, respectively), which were used regularly on many sampled chickens. Previous antimicrobial usage emerged as the only significant risk factor associated with increased detection of multi-drug resistant E. coli. Further surveillance and educational outreach about antimicrobial resistance and stewardship is recommended to reduce antimicrobial drug use and to limit the potential spread of resistance to antimicrobial drugs in Tanzania.

scholarly journals Dynamics and Diversity of Escherichia coli in Animals and System Management of the Manure on a Commercial Farrow-to-Finish Pig Farm

2012 ◽  
Vol 79 (3) ◽  
pp. 853-859 ◽  
Author(s):  
Mauricio Marchant ◽  
Miguel A. Moreno
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Resistance ◽  
Fecal Microbiota ◽  
Production Cycle ◽  
Public Health Perspective ◽  
Content Type ◽  
E Coli ◽  
Animal Populations ◽  
Full Production ◽  
Pig Farm

ABSTRACTThe objective of this study was to determine the dynamics and diversity ofEscherichia colipopulations in animal and environmental lines of a commercial farrow-to-finish pig farm in Spain along a full production cycle (July 2008 to July 2009), with special attention to antimicrobial resistance and the presence of integrons. In the animal line, a total of 256 isolates were collected from pregnant sows (10 samples and 20 isolates), 1-week-old piglets (20 samples and 40 isolates), unweaned piglets (20 samples and 38 isolates), growers (20 samples and 40 isolates), and the finishers' floor pen (6 samples and 118 isolates); from the underfloor pits and farm slurry tank environmental lines, 100 and 119 isolates, respectively, were collected. Our results showed thatE. colipopulations in the pig fecal microbiota and in the farm environment are highly dynamic and show high levels of diversity. These issues have been proven through DNA-based typing data (repetitive extragenic palindromic PCR [REP-PCR]) and phenotypic typing data (antimicrobial resistance profile comprising 19 antimicrobials). Clustering of the sampling groups based on their REP-PCR typing results showed that the spatial features (the line) had a stronger weight than the temporal features (sampling week) for the clustering ofE. colipopulations; this weight was less significant when clustering was performed based on resistotypes. Among animals, finishers harbored anE. colipopulation different from those of the remaining animal populations studied, considering REP-PCR fingerprints and resistotypes. This population, the most important from a public health perspective, demonstrated the lowest levels of antimicrobial resistance and integron presence.

Antimicrobial resistance patterns in urinary E. coli isolates after a change in a single center’s guidelines for uncomplicated cystitis in ambulatory settings

2019 ◽  
Vol 40 (05) ◽  
pp. 600-602
Author(s):  
Patrick P. Ryan ◽  
Bryan C. Knepper ◽  
Rachel M. Everhart ◽  
Connie S. Price
Keyword(s):  
Antimicrobial Resistance ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Significant Risk ◽  
E Coli ◽  
Outpatient Visits ◽  
Resistance Patterns ◽  
Uncomplicated Cystitis

AbstractRecommending nitrofurantoin to treat uncomplicated cystitis was associated with increased nitrofurantoin use from 3.53 to 4.01 prescriptions per 1,000 outpatient visits, but nitrofurantoin resistance in E. coli isolates remained stable at 2%. Concomitant levofloxacin resistance was a significant risk for nitrofurantoin resistance in E. coli isolates (odds ratio [OR], 2.72; 95% confidence interval [CI], 1.04–7.17).

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