scholarly journals Accuracy of 12 short versions of the Geriatric Depression Scale to detect depression in a prospective study of a high-risk population with different levels of cognition

2019 ◽  
pp. 1-10
Author(s):  
Simona Sacuiu ◽  
Nazib M. Seidu ◽  
Robert Sigström ◽  
Therese Rydberg Sterner ◽  
Lena Johansson ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
High Risk ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Depression Symptoms ◽  
High Risk Population ◽  
Geriatric Depression ◽  
Risk Population ◽  
Optimal Criterion ◽  
Short Versions

ABSTRACT Objectives: To determine the accuracy of 12 previously validated short versions of the Geriatric Depression Scale (GDS) to detect major depressive disorder (MDD) in a high-risk population with and without global cognitive impairment. Design: Cross-sectional study. Setting: Five hospitals, Western Sweden. Participants: Older adults (age ≥70 years, n = 60) assessed at a home visit 1 year after hospital care in connection with suicide attempt. Measurements: Depression symptoms were rated using the established 15-item GDS. Eleven short GDS versions identified by a recent systematic review were derived from this administered version. Receiver operating characteristic curves and area under the curve (AUC) for the identification of MDD diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, were obtained for each version. The Youden Index optimal criterion was used to determine the appropriate cutoffs. Analyses were repeated after stratification by cognitive status (Mini Mental State Examination score ≤24 and >24) for the best performing GDS short versions and the established 15-item GDS. Results: The 7-item GDS according to Broekman et al. (2011), with a cutoff 3, was the most accurate among the 12 short versions (AUC 0.90, 95% confidence interval 0.80–1.00), identifying MDD with sensitivity 88% and specificity 81%. The cutoff score remained consistent in the presence of global cognitive impairment, which was not the case for the standardized 15-item GDS. Conclusion: The Broekman 7-item GDS had high accuracy to detect MDD in this prospective clinical cohort at high risk for MDD. Further testing of GDS short versions in diverse settings is required.

A phase II study of enzalutamide (Enz) with dutasteride (Dut) or finasteride (Fin) in men ≥ 65 years with hormone-naive systemic prostate cancer (HNSPCa): Tolerability and geriatric asssessment (GA) results.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e16518-e16518
Author(s):  
Jason Zittel ◽  
Chunkit Fung ◽  
Dilip Sankar Babu ◽  
Elizabeth A. Guancial ◽  
Deepak M. Sahasrabudhe ◽  
...  
Keyword(s):  
High Risk ◽  
Phase Ii ◽  
Phase Ii Study ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Older Men ◽  
Geriatric Depression ◽  
Grade 5 ◽  
Common Grade ◽  
Grade 3

e16518 Background: Older men are at a high risk for adverse events (AEs) from androgen deprivation therapy (ADT). In this phase II study, we evaluated Enz and Dut/Fin in lieu of ADT for at-risk older patients with HNSPCa. Methods: Eligible patients were ≥65 years (y); at high risk of AEs from ADT by GA or treating physicians; metastatic (M1) or non-metastatic (M0) HNSPCa with a PSA doubling time ≤ 9 months and testosterone > 50ng/dl. They received Enz 160 mg/day and Dut 0.5 mg/day or Fin 5 mg/day until disease progression. GA was performed at baseline and week (wk) 61 and/or at the time of progression. GA included validated tests: Instrumental Activities of Daily Living (IADL), fall history, Short Physical Performance Battery (SPPB), Geriatric Depression Scale (GDS), and Montreal Cognitive Assessment (MOCA). The prevalence of impairment for each assessment was calculated; change in prevalence from baseline to wk 61 was analyzed using paired sample t-test. Results: 43 patients were enrolled in the study. Median age at enrollment was 78 y (range 66-94) and 93% were ECOG 0-1; 37% (n = 16) had M0 and 63% (n = 27) had M1 HNSPCa, with the majority (67%) having Gleason 6 or 7 disease. At baseline, 18.6% met the cutoff for impairment for IADLs, 53.7% for SPPB, 7.9% for GDS and 64.3% for MOCA; 9.8% had a recent fall. Median baseline PSA was 11.38 ng/ml (range: 2-145). At the time of analysis, 29 men (67.4%) remain on study treatment. 95.3%, 74.4% and 46.5% of patients reported at least one Grade 1, 2 or 3 AE respectively. No patient had a Grade 4 AE and one Grade 5 AE was reported but was an unrelated event. The most common Grade 3 AEs were hypertension (27.8%), GI (19.4%), and cardiac (8.3%); all Grade 3 GI AEs reported were deemed unrelated to the study drugs. Only impairment in ≥ 1 IADL showed a statistically significant increase in prevalence at wk 61 of treatment (40.6%) compared to baseline (18.6%, p = 0.036). Conclusions: For older men with HNSPCa, Enz with Dut/Fin demonstrated efficacy with reasonable toxicity profile, and no significant impact on the majority of GA domains. Clinical trial information: NCT02213107.

scholarly journals A Psychometric Properties Evaluation of the Italian Version of the Geriatric Depression Scale

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Giovanni Galeoto ◽  
Julita Sansoni ◽  
Michela Scuccimarri ◽  
Valentina Bruni ◽  
Rita De Santis ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Concurrent Validity ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Depression Symptoms ◽  
Italian Population ◽  
Geriatric Depression ◽  
Italian Version ◽  
Retest Reliability ◽  
Test Retest Reliability

Objective. The Geriatric Depression Scale (GDS) is an evaluation tool to diagnose older adult’s depression. This questionnaire was defined by Yesavage and Brink in 1982; it was designed expressly for the older person and defines his/her degree of satisfaction, quality of life, and feelings. The objective of this study is to evaluate the psychometric properties of the Italian translation of the Geriatric Depression Scale (GDS-IT). Methods. The Italian version of the Geriatric Depression Scale was administered to 119 people (79 people with a depression diagnosis and 40 healthy ones). We examined the following psychometric characteristics: internal consistency reliability, test-retest reliability, concurrent validity, and construct validity (factor structure). Results. Cronbach’s Alpha for the GDS-IT administered to the depressed sample was 0.84. Test-retest reliability was 0.91 and the concurrent validity was 0.83. The factorial analysis showed a structure of 5 factors, and the scale cut-off is between 10 and 11. Conclusion. The GDS-IT proved to be a reliable and valid questionnaire for the evaluation of depression in an Italian population. In the present study, the GDS-IT showed good psychometric properties. Health professionals now have an assessment tool for the evaluation of depression symptoms in the Italian population.

scholarly journals Usefulness of the Geriatric Depression Scale 15-item version among very old people with and without cognitive impairment

2013 ◽  
Vol 17 (5) ◽  
pp. 638-645 ◽  
Author(s):  
Mia Conradsson ◽  
Erik Rosendahl ◽  
Håkan Littbrand ◽  
Yngve Gustafson ◽  
Birgitta Olofsson ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Geriatric Depression ◽  
Old People ◽  
Very Old

Music Training Improves Depressed Mood Symptoms in Elderly People: A Randomized Controlled Trial

2019 ◽  
Vol 92 (1) ◽  
pp. 115-133 ◽  
Author(s):  
Michele Biasutti ◽  
Anthony Mangiacotti
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Depressed Mood ◽  
Mini Mental State Examination ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Control Group ◽  
Geriatric Depression ◽  
Music Training ◽  
State Examination

The effectiveness of music training on depressed mood and general cognitive function in elderly participants is verified in this study. Music activities consisted of improvisation exercises for stimulating interpersonal skills, mood, and cognitive functions. A mixed research method was adopted, including standardized measures (Mini-Mental State Examination and Geriatric Depression Scale) and follow-up semistructured interviews. The research design included pre- and postevaluation with randomized experimental and control groups. Participants were 45 care residents aged 62 to 95, healthy and with cognitive impairment. Results revealed a significant improvement in depression index (Geriatric Depression Scale) for the experimental period ( t = 1.450; p < .005; d = 0.453) while the control group had no improvement ( t = 0.080; p > .1; d = 0.025). In addition, a significant improvement was found in the cognitive level (Mini-Mental State Examination) for the experimental ( t = 2.300; p < .005; d =  0.668) than the control group that had a significant reduction ( t = 1.240; p < .05; d = 0.273). This study provides evidence that music training has a positive impact on depressed mood and general cognitive function in elderly participants. These types of music training sessions could provide aid to control the symptoms of depression, delay the deterioration of cognitive function, and enhance social–cognitive function, especially in individuals presenting with cognitive impairment.

Community reintegration: Therapeutic dining program for older adult following stroke

2009 ◽  
Vol 8 (3) ◽  
pp. 7-18
Author(s):  
Christina Harper
Keyword(s):  
Older Adults ◽  
Nutritional Status ◽  
Older Adult ◽  
Barthel Index ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Self Esteem ◽  
Depression Symptoms ◽  
Community Reintegration ◽  
Geriatric Depression

Therapeutic dining programs are part of the community reintegration process for clients recovering from a stroke. It is a supervised program performed in social settings that consists of a combination of techniques to improve the eating situation. Therapeutic dining programs are a beneficial form of therapy for many rehabilitative groups. This specific program has been tailored to older adults who are recovering from a stroke. Its main goals, aside from improving the eating situation, are to prevent another stroke from happening and decrease depression symptoms and increase self-esteem by reintegrating clients back into the community. I looked into several different community reintegration program and nutrition and eating after stroke studies in which positive outcomes were found for post-stroke clients. All studies and research used has provided a strong support for the specific proposed intervention program for my client Kelly, who is an older adult female recovering from a stroke. Assessments selected: The Barthel Index, Nutritional Status, and Geriatric Depression Scale (GDS). Plan: Small group therapeutic dining program with other older adults in the afternoon. Intervention: Therapeutic Dining Program three times a week for eight weeks to improve eating situation, promote healthy eating, decrease symptoms of depression, and increase self esteem and social activity. Evaluation: The Barthel Index, Nutritional Status, Geriatric Depression Scale plus a Stroke Recovery Scorecard. Clients Goals: 1) Client will lower the risks of having another stroke. 2) Client will increase their eating situation experience and self-esteem while decreasing their depression symptoms. 3) Client will get involved in one support group or leisure activity outside of recreational therapy (RT) dining program for community reintegrated leisure pursuits.

scholarly journals A cross sectional study on screening for depression among elderly in rural areas of Puducherry, India

2018 ◽  
Vol 7 (1) ◽  
pp. 46
Author(s):  
Pamagal Kavithai ◽  
Anandaraj R. ◽  
Buvaneswary S. ◽  
Prakash M.
Keyword(s):  
Cognitive Impairment ◽  
Sleep Problems ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Geriatric Depression ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elderly Individuals ◽  
Study Setting

Background: Depression among elderly has been a neglected health issue. Various factors hinder its early diagnosis. The objectives of this study are to screen for depression among elderly using geriatric depression scale-15 and to determine its influencing factors.Methods: A community based cross sectional study on geriatric depression was done in villages catered by a primary health centre in Puducherry. Permanent residents of the study setting, aged ≥60 years consenting for the study were included. Line listing of elderly individuals in the study setting was done and subjects were selected by simple random sampling. A pretested structured questionnaire was used to collect socio-demographic and clinic-psychological variables. Hindi mental state examination scale was used to screen for cognitive impairment (score <23). Geriatric Depression Scale (GDS-15) was used to screen for depression (score >5) among geriatric individuals. Appropriate statistical tests of significance were done.Results: Among the 360 elderly individuals screened using GDS-15 tool, 41.4% of them were found to be at a higher risk of developing depression. Significant factors for risk of depression in univariate analysis include being female, illiterate, unemployed, widow/single, having sleep problems, dependency in activities of daily living and cognitive impairment. Predictors for risk of depression evident by multivariate analysis include presence of unemployment, sleep problems and cognitive impairment.Conclusions: A higher proportion of elderly was observed to be at risk of depression.  Primary care physicians may consider screening for depression in elderly with identified risk factors and act accordingly.

Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment?

2009 ◽  
Vol 24 (6) ◽  
pp. 556-562 ◽  
Author(s):  
Hans Debruyne ◽  
Michael Van Buggenhout ◽  
Nathalie Le Bastard ◽  
Marcel Aries ◽  
Kurt Audenaert ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Elderly Patients ◽  
Screening Tool ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Geriatric Depression
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