Making sense of time

2001 ◽  
Vol 9 (1) ◽  
pp. 43-58
Author(s):  
JOHN A. MICHON

From the psychonomic point of view time is the conscious experiential product of the processes that enable the (human) organism to organize itself adaptively so that its behaviour stays tuned to the sequential contingencies afforded by its environment. This paper reviews some recent insights into the functioning of the timekeepers – clocks and regulators, organic and virtual – that make up the human ‘sense of time’.

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Vladimir Mitev

This publication examines the notion of ‘cross-border journalism’ in its western form. It also attempts to present an alternative cross-border journalism based on the experience of the author with the Romanian-Bulgarian “The Bridge of Friendship” blog and the impressions received from other Bulgarian cross-border websites. The international brand of cross-border journalism is used for investigations – such as “The Panama Papers” – which involve the cooperation of journalists from various countries. The kind of cross-border journalism found in the “Bridge of Friendship” blog is both local and regional. It does not have an investigative element but it tries to bring about change through the mutual knowledge and understanding of Romanians and Bulgarians. It defines a Bulgarian-Romanian point of view of the world and presents the common Romanian-Bulgarian spaces in politics, economy and culture.


2018 ◽  
pp. 669-677 ◽  
Author(s):  
I. ZOFKOVA

The skeleton shows an unconventional role in the physiology and pathophysiology of the human organism, not only as the target tissue for a number of systemic hormones, but also as endocrine tissue modulating some skeletal and extraskeletal systems. From this point of view, the principal cells in the skeleton are osteocytes. These cells primarily work as mechano-sensors and modulate bone remodeling. Mechanically unloaded osteocytes synthetize sclerostin, the strong inhibitor of bone formation and RANKL, the strong activator of bone resorption. Osteocytes also express hormonally active vitamin D (1,25(OH)2D) and phosphatonins, such as FGF23. Both 1,25(OH)2D and FGF23 have been identified as powerful regulators of the phosphate metabolism, including in chronic kidney disease. Further endocrine cells of the skeleton involved in bone remodeling are osteoblasts. While FGF23 targets the kidney and parathyroid glands to control metabolism of vitamin D and phosphates, osteoblasts express osteocalcin, which through GPRC6A receptors modulates beta cells of the pancreatic islets, muscle, adipose tissue, brain and testes. This article reviews some knowledge concerning the interaction between the bone hormonal network and phosphate or energy homeostasis and/or male reproduction.


2019 ◽  
Vol 70 (5) ◽  
pp. 1884-1887
Author(s):  
Raoul Vasile Lupusoru ◽  
Gabriel Topor ◽  
Ingrith Crenguta Miron ◽  
Mihaela Grigore ◽  
irina Esanu

In so-called general pathology, the centre of gravity must fall precisely on the experimental pathology, on the analysis of experimental pathological processes. To understand the life of a diseased organism, it is necessary to know the morphological changes at different stages of development of the pathological processes. Morphopathology deals with the study of morphological changes in a diseased organism. Both disciplines, namely both pathophysiology, as well as morphopathology, complement each other and together constitute a vast field of medical knowledge, namely the so-called pathology (pathos = suffering, disease, and logos = science). Physiopathology uses the data of the morphological changes found as a result of the pathological processes and it is closely related to the pathological anatomy, which deals with the same problems, but from another point of view: both have the same object of study, namely, the diseased human organism. Any pathological action provokes from the very beginning a defence of the body, directed against the injurious agent or the lesion. Pathological phenomena are recognized not only by studying the functional changes of the body and its various parts; taking into account the unity between function and form, it is necessary to study the morphological changes. From the research carried the following resulted: from the total of 165 cases, 102 cases (61.81%) presented diabetes, 34 cases (20.62%) obesity, 29 cases (17.57%) gout. In the treatment of oral mucosal lesions, strong antiseptics will be avoided since these are necrotizing (multiple cases of diabetic angiopathy are known), attention should also be paid to performing fixed or mobile prosthetic works that do not have to traumatize the periodontium and the mucosa of the prosthetic field in order to avoid the possibility of over-infection. Avoid bleeding manoeuvres in case of a diabetic patient with high blood sugar, taking into account the risk of diabetic coma.


1996 ◽  
Vol 35 (01) ◽  
pp. 8-11
Author(s):  
I. Dimitrov

AbstractEach science is identified with the questions it raises with respect to its object of study. This paper discusses the formulation of the basic questions of medical informatics. From a historical point of view, it first dealt with the problems of medical computing. Thereby, three classical questions arose: How can existing computers and information technologies assist in medical activities? Which components of the mathematical apparatus of informatics can be used for solving medical problems, and how and what activities of a physician are subject to algoritmization? The present time raises a new circle of questions centered around the basic one: How is the information system of the human organism structured and how does it function? This question and others form the basis of a new trend in medical informatics.


In a follow-up to Comics as Philosophy, this book addresses two questions: which philosophical insights, concepts, and tools can shed light on the graphic novel? And how can the graphic novel cast light on the concerns of philosophy? Each chapter ponders a well-known graphic novel to illuminate ways in which philosophy can untangle particular combinations of image and written word for deeper understanding. The chapters examine notable graphic novels within the framework posited by these two questions. One chapter discusses how a philosopher discovered that the panels in Jeff Lemire's Essex County do not just replicate a philosophical argument, but they actually give evidence to an argument that could not have existed otherwise. Another chapter reveals how Chris Ware's manipulation of the medium demonstrates an important sense of time and experience. Still another describes why Maus tends to be more profound than later works that address the Holocaust because of, not in spite of, the fact that the characters are cartoon animals rather than human. Other works contemplated include Will Eisner's A Contract with God, Alan Moore and David Lloyd's V for Vendetta, Alison Bechdel's Fun Home, and Joe Sacco's Footnotes in Gaza. Mainly, each author, graphic novelist, and artist are all doing the same thing: trying to tell us how the world is—at least from their point of view.


2014 ◽  
Vol 35 (2) ◽  
pp. 204-227
Author(s):  
Alexander T. Englert

AbstractThe goal of this paper is to clarify the role ‘wrong’ plays in Hegel’s system of right, as both a form of freedom and the transition to morality. Two approaches will be examined to explore wrong in practical philosophical terms: First, one could take the transition to bedescriptivein nature. The transition describes wrong as a realized fact of the human condition that one inherits from the outset. Second, one could see it asprescriptive. Actual wrongdoing would be essential for the subject’s progression tobecoming moral. Though both are most likely the case, emphasis is given to the latter since it represents the actualization of potential. Furthermore, it will be suggested that wrong plays a similar role as that which alienation does in thePhenomenology of Spirit; both bridge the will as abstract personality with the moral point of view.


2009 ◽  
Vol 415 ◽  
pp. 37-40
Author(s):  
Ion Iosub ◽  
Viorel Malinovschi ◽  
Victor Grigorie ◽  
Alina Murariu ◽  
Aurelia Meghea

The environmental impact on human health is of increasing concern mainly due to the complex interaction between various hazardous factors both on environment and within human organism. The aim of this paper is to investigate possible correlations between the quality parameters of drinking water and the formation of uroliths. The constituents of some kidney calculi sampled after surgery from 90 patients coming from the Horezu – Valcea area have been analysed, this region being identified as having the most cases of kidney lithiasis and that might be related with hard drinking waters. The study has been made during the period of 2004 – 2008. Physical – chemical methods specific for characterization of the quality of drinking waters have been used in parallel with determination of composition and structural characterization by X-ray diffraction, thermal analysis TG, ATD, FT-IR spectroscopy, optical microscopy. Four groups of uroliths have been identified: multiphase oxalate and urate, phosphate (hydroxiapatite) and carbonate, monohydrated oxalate (whewellite), and urate stones. Such research might be useful, from both chemical and biochemical point of view, for identifying the conditions that cause the inhibition of the processes related to kidney calculi formation.


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