Neuroscience and Psychopharmacology into the Next Millennium

CNS Spectrums ◽  
1999 ◽  
Vol 4 (7) ◽  
pp. 36-52
Author(s):  
Robert J. Birnbaum
Keyword(s):  
Antipsychotic Agents ◽  
Clinical Applications ◽  
Disease Pathogenesis ◽  
Neuropsychiatric Disease ◽  
Disease States ◽  
Common Practices ◽  
Atypical Antipsychotic Agents ◽  
The Common ◽  
Shed Light ◽  
Single Lesion

AbstractThe end of the millennium provides an opportunity to review some of the common practices that were present in psychopharmacology during the 20th century. The author focuses on two approaches that have dominated research and guided the clinical application of psychopharmacologic therapeutics: the unitary clinically-based and single-lesion perspectives. The author expands upon these older formulations of neuropsychiatric disease pathogenesis and describes how the approach to psychopharmacologic research and therapeutics has changed in light of advances in the basic neurosciences. Relevant recent advances in the basic neurosciences that shed light on the pathophysiology of neuropsychiatric disease states and that guide psychopharmacologic practices are described. The use of atypical antipsychotic agents to treat schizophrenia is given as one example of the clinical applications of the approach to psychopharmacology in the next century.

scholarly journals Über einige Aspekte des diplomatischen Verkehrs zwischen dem Hochmeister und Kaiser Sigismund von Luxemburg

2021 ◽  
Vol 26 ◽  
pp. 91-107
Author(s):  
Přemysl Bar
Keyword(s):  
Primary Sources ◽  
The Political ◽  
Late Medieval ◽  
Medieval Europe ◽  
Common Practices ◽  
Research Findings ◽  
The Common ◽  
Characteristic Features ◽  
Mutual Relations ◽  
Shed Light

On some aspects of the diplomatic traffic between the Grand Master of the Teutonic Order and Emperor Sigismund of Luxembourg   The diplomatic traffic between the Grand Master of the Teutnic Order and Emperor Sigismund of Luxembourg was carried out according to the common practices of diplomacy in late medieval Europe. Nevertheless, this topic deserves further exploration due to Sigismund’s efforts to impose suzerainty upon the Grand Master and the Teutonic Knights. This issue influenced their mutual relations after Sigismund’s election as Roman-German King in 1410/1411. There are numerous surviving sources, especially in the archive of the Teutonic Order in Berlin (GStA PK), such as legation’s instruction, dispatches and, last but not least, the political correspondence between the Grand Master and Emperor Sigismund. These sources can shed light not only on the complicated diplomatic relation between above-mentioned two entities, but also, due to richness of their content, on late medieval diplomacy in general. Based upon the research findings by Klaus Neitmann, who explored the Order’s legation exclusively, this paper tries to expand the field of research by including the legations of Sigismund. From this perspective only several selected aspects of the topic are examined in the study: 1) defining a legation (foreign mission) and its characteristic features; 2) the diplomatic traffic between the Grand Master and Sigismund of Luxembourg from a prosopographical perspective; and 3) the personal composition and communication at the court of Sigismund. The richness of sources makes new questions possible concerning not only this specific diplomatic traffic, but also late medieval diplomacy in general as well. However, the definite answers might be delivered after compiling a thorough list of all legations from both sides, which in light of the large number of primary sources must be reserved for another study.

KOMIK DI LINGKARAN INDUSTRI MUSIK

DeKaVe ◽  
2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Terra Bajraghosa
Keyword(s):  
Comic Books ◽  
Music Industry ◽  
Comic Book ◽  
Narrative Approach ◽  
Visual Narrative ◽  
Common Practices ◽  
Visual Style ◽  
Song Lyrics ◽  
The Common

Comic ges. Based on comprehention as a narrative media, comics in Indonesia are oftenly compared to bas-reliefs on Borobudur temple and Wayang Beber.. From many kind of stories Indonesian comic books recently offered, with the developed visual wrapping, some comics steal attentions by its unique themes. These comic books are created because of the inspiration and relation to music industry. These comic books couldn't be seen from the visual style alone, as they were created in many visual genres, but they could be seen from their relations to music industry, whether the mainstream or indie ones. These comic books are published together with the music CDs, telling fictional stories from factual bands or musicians, telling a band's factual stories, or created by one of the band members. To understand modes of creation of these music industry-related-comic books, visual narrative approach will be applied. Through visual narrative approach, the band members' or musician's necessity for telling stories via comics, beside the common practices via music and song lyrics, will be observed.Keywords : Comic book, music industry, visual narrative

scholarly journals Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment

2021 ◽  
Vol 22 (10) ◽  
pp. 5278
Author(s):  
Andrew E. Massey ◽  
Shabnam Malik ◽  
Mohammad Sikander ◽  
Kyle A. Doxtater ◽  
Manish K. Tripathi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tumor Microenvironment ◽  
Intercellular Communication ◽  
Targeted Drug Delivery ◽  
Clinical Implications ◽  
Disease States ◽  
Significant Research ◽  
The Common ◽  
Targeted Drug ◽  
Loading Methods

Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implications.

El Concepto De La lingüística Cognitiva En La Poesía Traducida Análisis Semántico Según La Teoría del Esquema Básico De La Referencia

2021 ◽  
Vol 29 ◽  
Author(s):  
Ahmed Hameed Abdulmajeed Abeer Hussein Abid
Keyword(s):  
Cognitive Linguistics ◽  
Semantic Analysis ◽  
Research Work ◽  
Speech Community ◽  
Search For Meaning ◽  
Basic Scheme ◽  
Scheme Theory ◽  
The Common ◽  
Symmetry Relations ◽  
Shed Light

This research work is part of a project to get an M.A. degree. Some of the linguistic sciences specialized in the search for meaning in the text, such as semantics, pragmatics, cognitive linguistics and etc. will be clarified. Besides, we shed light on the elements of semantic analysis with examples according to the basic scheme theory of reference, which indicates that the language is of a fictional nature. As it is a variety of similarity and symmetry relations between the form of the word and its meaning, whether it is phonetic or written or related to metaphor, metonymy or analogy, and it is not a random relationship. In all these genres, a very important role is played by imaginative comprehension, which subsequently acquires a traditional character and spreads due to the common collective understanding of the word among speakers of the speech community.

Adverse Effects of Atypical Antipsychotic Agents and Their Effects on Quality of Life

2004 ◽  
Vol 24 (7) ◽  
pp. 843-847 ◽  
Author(s):  
Beth M. Dubisar ◽  
Steven C. Stoner ◽  
James Reynolds ◽  
Rintu Khan ◽  
Leonard Ramlatchman
Keyword(s):  
Quality Of Life ◽  
Adverse Effects ◽  
Atypical Antipsychotic ◽  
Antipsychotic Agents ◽  
Atypical Antipsychotic Agents

scholarly journals The bodily community. The gesture and the rhythm as manners of the living-together

2019 ◽  
Vol 2 (1) ◽  
pp. 10-23
Author(s):  
Maricica Munteanu
Keyword(s):  
Personal Identity ◽  
The Body ◽  
Social Aspects ◽  
Formal Approach ◽  
Ethical Implications ◽  
Common Space ◽  
Ethical Debate ◽  
Living Together ◽  
Common Practices ◽  
The Common

The present article explores the collective imaginary of the cenacle, referring to the case of Viața românească literary group from Iași, focussing on the bodily community and its representations in the common space, understood as space-in-common. This approach shifts the interest from the ideological component that is the ‘poporanism’, as promoted by Viața românească revue, to the ethical and social aspects of the community. This does not mean that the bodily community is “more real” than the ideological community, or that it translates with fidelity the common practices of the cenacle; the bodily community is in fact another form of representation, a phantasm of the living-together, analysed through Roland Barthes’s theory as the space where solitude and sociability coexist. The corporal representations of the community, always engaged in an ethical debate, is further discussed through two manners of the living-together: the gesture and the rhythm. The theoretical reference of this analysis is Marielle Macéʼs book Styles. Critique de nos formes de vie, which proposes a formal approach of life, concentrating on the ethical implications. The issues derived from this sort of reading state the relation between the body and the environment, the vicinities and the somatic interactions between the members of the cenacle, the adjustment of distances, and the maintenance of solitude inside the community. The gestures, attitudes, behaviour, verbal and non-verbal tics, clothing, the manners of speech or the rhythm of doing certain things are seen not as marks of personal identity that positions itself inside the spaces of power, but as collective signs, as form of encounter and interaction, of exposure to the others but also responsiveness of the others, of expropriation as well as appropriation, of affirmation as well as alteration of the forms of life.

scholarly journals More Irrigated Crop Production with Less Water Use

2019 ◽  
pp. 218-226
Author(s):  
Ahmed Ibrahim Ekhmaj ◽  
Younes Daw Ezlit ◽  
Mukhtar Mahmud Elaalem
Keyword(s):  
Crop Yield ◽  
Irrigation Water ◽  
Performance Indicators ◽  
Unit Volume ◽  
Unit Area ◽  
Irrigation Management ◽  
Agricultural Practices ◽  
Common Practices ◽  
The Common ◽  
Production Output

Three major performance indicators developed by the International Water Management Institute (IWMI, 1998) are used in this paper to evaluate the performance of the irrigated crops in the region according to the commonly followed practices among farmers as compared with their performance under conditions of much improved irrigation management and agricultural practices. These indicators include the Standardized Gross Value Production (SGVP), the unit area production output (crop yield or its financial value per hectare) and the unit volume of irrigation water production output (crop yield or its financial value per cubic meter). The comparison between the two agricultural practices indicated that the unit area output of the common practices among farmers did not exceed 6483 Libyan Dinars / hectare, while that under the improved practices was 11605 Libyan Dinars / hectare. The unit volume of irrigation water output for the common practices was 0.63 Libyan Dinar / cubic meter, while that under the improved practices reached 1.63 Libyan Dinar / cubic meter. These results clearly show the importance of the applied performance indicators in the assessment and clarification of the economic impacts of any introduced interventions aiming at the improvement of and/or the differentiation among irrigation management practices and alternative agricultural cropping systems.

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