Ultrafast SET-LRP with Peptoid Cytostatic Drugs as Monofunctional and Bifunctional Initiators

2017 ◽  
Vol 18 (8) ◽  
pp. 2610-2622 ◽  
Author(s):  
Gerard Lligadas ◽  
Mojtaba Enayati ◽  
Silvia Grama ◽  
Rauan Smail ◽  
Samuel E. Sherman ◽  
...  
Keyword(s):  
Cytostatic Drugs ◽  
Bifunctional Initiators

Protective influence of coded amino acids on the development of liver tissue culture in the presence of cytostatic

2020 ◽  
pp. 48-53
Author(s):  
N. I. Chalisova ◽  
V. K. Kozlov ◽  
A. B. Mulik ◽  
E. P. Zatsepin ◽  
T. A. Kostrova
Keyword(s):  
Amino Acids ◽  
Tissue Culture ◽  
Side Effects ◽  
Liver Tissue ◽  
Organotypic Culture ◽  
Growth Zone ◽  
Inhibitory Effect ◽  
Cytostatic Drugs ◽  
Urgent Problem ◽  
Combined Exposure

An urgent problem is the search for substances that can provide a protective effect in cases of DNA synthesis and repair disorders that arise as a result of side effects of cytostatic drugs used in the treatment of cancer. The aim of this work was to study the effect of 20 encoded amino acids in the presence of Cyclophosphane on the development of organotypic culture of rat liver tissue. The results obtained indicate that Cyclophosphane; which simulates the action of such cytostatic substances; inhibits cell proliferation in the liver tissue. It was also found that the encoded amino acids: asparagine; arginine; and glutamic acid; eliminate the inhibitory effect of Cyclophosphane in liver tissue culture. The growth zone of explants after combined exposure to Cyclophosphane (whose isolated action suppressed the growth zone) and these amino acids increased significantly and reached control values. Thus; the experimental data create the basis for the development of methods for the therapeutic use of the three studied amino acids for the removal of side effects in the treatment with cytostatic drugs.

ABATEMENT OF ANTICANCER DRUGS VIA ELECTROCHEMICAL OXIDATION PROCESS: A REVIEW

2020 ◽  
pp. 1-4
Author(s):  
CHARULATA SIVODIA ◽  
ALOK SINHA
Keyword(s):  
Anticancer Drugs ◽  
Cell Function ◽  
Electrochemical Techniques ◽  
Aquatic Organisms ◽  
Pharmaceutical Drugs ◽  
Cytostatic Drugs ◽  
Cancerous Cell ◽  
Pharmaceutical Removal ◽  
Mutagenic Effects ◽  
Made In

The advancement made in biomedical industry upsurges the consumption rate of pharmaceutical drugs. The lack of proper monitoring and regulation methods leads to the unregulated discharge of pharmaceuticals in wastewater, where it can affect the aquatic organisms. Anticancer drugs are also known as cytostatic drugs mainly used for the treatment of cancer by disrupting the cell function and prevent multiplication of cancerous cell. Therefore, anticancer drugs are suspected to pose potential risk on environment by influencing mutagenic effects on the cells of aquatic organisms. An extensive research has been already made in the field of pharmaceutical removal, however their application on the removal of anticancer drugs is limited. This review paper elucidates about different electrochemical techniques for the mitigation of cytostatic drugs.

Prostate Cancer, miRNAs, Metallothioneins and Resistance to Cytostatic Drugs

2013 ◽  
Vol 20 (4) ◽  
pp. 534-544 ◽  
Author(s):  
V. Pekarik ◽  
J. Gumulec ◽  
M. Masarik ◽  
R. Kizek ◽  
V. Adam
Keyword(s):  
Prostate Cancer ◽  
Cytostatic Drugs

Determination of cytostatic drugs in Besòs River (NE Spain) and comparison with predicted environmental concentrations

2017 ◽  
Vol 24 (7) ◽  
pp. 6492-6503 ◽  
Author(s):  
Helena Franquet-Griell ◽  
Deborah Cornadó ◽  
Josep Caixach ◽  
Francesc Ventura ◽  
Silvia Lacorte
Keyword(s):  
Cytostatic Drugs ◽  
Environmental Concentrations ◽  
Predicted Environmental Concentrations ◽  
Ne Spain

Haemoprotection against cytostatic drugs by stem cell inhibition

1991 ◽  
Vol 12 ◽  
pp. 304-310 ◽  
Author(s):  
Marie-Hélène Moser ◽  
Walter R. Paukovits
Keyword(s):  
Stem Cell ◽  
Cytostatic Drugs ◽  
Cell Inhibition

Glucocorticoids enhance interleukin-4 production to neo-antigen (hyaluronidase) in children immunocompromised with cytostatic drugs

2002 ◽  
Vol 13 (5) ◽  
pp. 375-380 ◽  
Author(s):  
Monika Edelbauer ◽  
Marianne Gerstmayr ◽  
Christine Loibichler ◽  
Eva Jost ◽  
Martina Huemer ◽  
...  
Keyword(s):  
Interleukin 4 ◽  
Cytostatic Drugs

Modulation of cytotoxicity of cytostatic drugs by hemodialysis in vitro and in vivo

1990 ◽  
Vol 17 (2-3) ◽  
pp. 293-300 ◽  
Author(s):  
Hansjörg Sauer ◽  
Klaus Füger ◽  
Matthias Blumenstein
Keyword(s):  
Cytostatic Drugs
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