Global variations in peak bone mass as studied by dual-energy X-ray absorptiometry

2004 ◽  
Vol 259 (2) ◽  
pp. 341-345 ◽  
Author(s):  
E. V. McCloskey ◽  
A. Dey ◽  
R. M. Parr ◽  
N. Aras ◽  
A. Balogh ◽  
...  
Keyword(s):  
Bone Mass ◽  
Peak Bone Mass ◽  
Dual Energy ◽  
X Ray

scholarly journals Autoimmunological serum parameters and bone mass density in premature ovarian insufficiency: a retrospective cohort study

2020 ◽  
Author(s):  
Klara Beitl ◽  
Klara Rosta ◽  
Nina Poetsch ◽  
Manuel Seifried ◽  
Daniel Mayrhofer ◽  
...  
Keyword(s):  
Bone Mass ◽  
Retrospective Cohort ◽  
Mass Density ◽  
Dual Energy ◽  
Premature Ovarian Insufficiency ◽  
Bone Mass Density ◽  
Ovarian Insufficiency ◽  
X Ray ◽  
T Score ◽  
Normal Women

Abstract Purpose It is still not clear whether to screen women with primary premature ovarian insufficiency for autoimmunity. Moreover, a possible association of autoimmunity with decreased bone mass density in premature ovarian insufficiency patients has not been evaluated. Thus, the objectives of this study were to review our experience with the use of an autoimmune screening panel in premature ovarian insufficiency women and to focus on bone mass density. Methods In a retrospective cohort study, 76 chromosomally normal women with primary premature ovarian insufficiency were included. The main outcome parameters were the results of an autoimmune screening panel and of dual-energy X-ray absorptiometry. Results Median age was 33 years. Sixty percent of premature ovarian insufficiency patients revealed abnormal dual-energy X-ray absorptiometry results (minimal T-score < −1.0). Any signs of autoimmunity were found in 21 women (36.2%). The most frequent abnormal results were increased thyroperoxidase antibodies (24.1%) and thyroglobulin antibodies (20.7%). A longer duration of amenorrhea (β = −0.015; p = 0.007), any abnormality during autoimmune screening (β = −0.940; p = 0.010), and a lower body mass index (β = −0.057; p = 0.036) were associated with a lower minimal T-score. Conclusion In chromosomally normal women with primary premature ovarian insufficiency, the prevalence of autoimmunity and decreased bone mass density seem high. Our data highlight the association between autoimmune abnormalities and decreased dual-energy X-ray absorptiometry results.

Pharmacy-Based Bone Mass Measurement to Assess Osteoporosis Risk

2002 ◽  
Vol 36 (4) ◽  
pp. 571-577 ◽  
Author(s):  
Mary E Elliott ◽  
Patrick D Meek ◽  
Nathan L Kanous ◽  
Gary R Schill ◽  
Patricia A Weinswig ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Mass ◽  
Calcium Intake ◽  
Dual Energy ◽  
Rural Elderly ◽  
Community Pharmacies ◽  
X Ray ◽  
Medical Interventions ◽  
To Receive ◽  
Peripheral Bone

OBJECTIVE: To evaluate elderly women's knowledge of their skeletal status, assess adequacy of calcium intake, determine the prevalence of low bone density, and determine whether peripheral bone density testing led to medical interventions in a group of rural, elderly Wisconsin women recruited in community pharmacies. DESIGN: Recruiting notices were posted in each pharmacy, and eligible women were enrolled in the order in which they volunteered. Each completed a fracture-risk questionnaire. Calcaneal bone density was measured within the following 6 weeks, using peripheral dual-energy X-ray absorptiometry. Mail surveys were used to assess interventions subsequent to the womens' study participation. SETTING: The study was conducted at 5 community pharmacies in rural Wisconsin. RESULTS: Of 133 women, 20% had calcaneal osteoporosis, defined as a T score ≤2.5 (calcaneal bone density <2.5 SDs below the young reference database). Thirty percent of women met National Osteoporosis Foundation (NOF) treatment criteria based on heel bone density and NOF-designated risk factors. Of those meeting treatment criteria, 75% were unaware of their low bone mass. Half of the women received <1200 mg/d of calcium, the recommended dose for osteoporosis prevention. Those who were taking a calcium supplement were much more likely to receive the recommended amount. Women who had discussed bone density test results with their physicians were more likely to receive central dual energy X-ray absorptiometry (DXA) measurements and/or start antiresorptive therapy than women who did not. CONCLUSIONS: Rural, elderly Wisconsin women are at substantial risk for osteoporosis, based on calcaneal bone density, but most are unaware of their risk. Compounding this risk is low calcium intake. Community screening of rural, elderly women by peripheral bone density measurement can lead to medical interventions in such individuals.

Sign in / Sign up

Export Citation Format

Share Document