A Green Tea Extract High in Catechins Reduces Body Fat and Cardiovascular Risks in Humans*

Obesity ◽  
2007 ◽  
Vol 15 (6) ◽  
pp. 1473-1483 ◽  
Author(s):  
Tomonori Nagao ◽  
Tadashi Hase ◽  
Ichiro Tokimitsu
2014 ◽  
Vol 10 (4) ◽  
pp. 209
Author(s):  
Ernawati Hardani ◽  
Wiryatun Lestariana ◽  
Susetyowati Susetyowati

Background: Overweight and obesity can cause high body fat total and lipid profile in the blood that brings risk for diseases to the bearer. Some studies on green tea extract supplementation have been undertaken to find out its effect on the fat reduction in children, men, and mice and the result showed a reduction in body fat, weight, appetite, and triglyceride level. This study uses green tea extract supplemented to overweight and obese women. Objective: To find out the reduction of body fat total and lipid profile (total cholesterol, triglyceride, LDL, HDL) in the blood of overweight and obese women personnel of Yogyakarta Municipal Health Office supplemented with green tea extract.Method: The study was randomized double-blinded control trial. The subject of the study was overweight and obese women of 35-55 years old personnel of Yogyakarta Municipal Health Office. Samples were 86 women randomly taken, comprising experiment group and control group, each of which consisting of 43 women. Each group had diet according to individual appetite. Both groups were given capsules of similar form and color but different ingredients: placebo and green tea extract. The experiment took three months. Blood was taken before and after the experiment to identify lipid profile (total cholesterol, triglyceride, LDL, HDL). Body fat total was examined using body fat analyzer. Data analysis used paired t-test.Results: Green tea extract supplementation could significantly reduce body fat total and insignificantly reduce cholesterol level, triglyceride, and LDL, significantly increase HDL in overweight and obese women.Conclusion: Green tea extract supplementation could reduce body fat total and increase HDL (p<0.005).


2020 ◽  
Vol 3 (2) ◽  
pp. 354-360
Author(s):  
Nafi'ah Nafi'ah ◽  
◽  
Mu’jizatillah Mu’jizatillah ◽  
Jhudi Bonosari Soediono

In last decade there has been an increase prevalence of overweight adolescents. Various strategies and products have been evaluated in effort to prevent and treat overweight using Green Tea Extract (GTE) and Senobi Breathing Exercise (SBE). However, the effect of GTE and SBE on decreasing adolescent body fat percentage in acute conditions when combined are unknown. The method used quasi experimental with control group design. The research conducted in Gymnasium laboratory of the Politeknik Unggulan Kalimantan in March 2020. The samples used were aged 18-21 years with BMI 25-29.9. Determination of samples using Federer's formula: (t-1) (n-1) ?15 obtained 4 treatment groups with a sample size of each group are 10 people that divided into: (a) overweight GTE; (b) overweight SBE; (c) overweight GTE and SBE; (d) overweight control . Measurement percentage of body fat in acute conditions shortly after treatment utilize Body Fat Monitor Scale GEA Medical EF 981. Statistical Test using Krusskall Wallis , the results obtained were P> 0.05, which indicates that there was no significant effect of GTE and SBE to reduce prevalence of adolescent body fat in acute conditions. Further research is needed to find out the correct protocol.


PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0120142 ◽  
Author(s):  
Shinichi Meguro ◽  
Takahiro Hasumura ◽  
Tadashi Hase

Planta Medica ◽  
2011 ◽  
Vol 77 (05) ◽  
Author(s):  
A Ali ◽  
X Yang ◽  
Q Shi ◽  
J Greenhaw ◽  
WF Salminen

2017 ◽  
Vol 23 (4) ◽  
pp. 35-41
Author(s):  
Jeong Hee Park ◽  
Hang Yeon Jeong ◽  
Jeong Yong Cho ◽  
Jae Hak Moon

2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Lisni Noraida Waruwu ◽  
Maria Bintang ◽  
Bambang Pontjo Priosoeryanto

Green tea (Camellia sinensis) is one of traditional plants that have the potential as an anticancer. The sample used in this research commercial green tea extract. The purpose of this study was to test the antiproliferation activity of green tea extract on breast cancer cell MCM-B2 in vitro. Green tea extract fractionated using three solvents, ie water, ethanol 70%, and n-hexane. Extract and fraction of green tea water have value Lethality Concentration 50 (LC50) more than 1000 ppm. The fraction of ethanol 70% and n-hexane had an LC50 value of 883.48 ppm and 600.56 ppm, respectively. The results of the phytochemical screening of green tea extract are flavonoids, tannins, and saponins, while the phytochemical screening results of n-hexane fraction are flavonoids and tannins. Antiproliferation activity was tested on breast cancer cells MCM-B2 and normal cells Vero by trypan blue staining method. The highest MCM-B2 cell inhibitory activity was achieved at a concentration of 13000 ppm green tea extract and 1000 ppm of n-hexane fraction, 59% and 59%, respectively. The extract and n-hexane fraction of green tea are not toxic to normal Vero cells characterized by not inhibiting normal cell proliferation. Keywords: antiproliferative, cancer cell MCM-B2, commercial green tea, cytotoxicity


2020 ◽  
Vol 21 (1) ◽  
pp. 31-35
Author(s):  
Basma El-Desoky ◽  
Shaimaa El-Sayed ◽  
El-Said El-Said

Objective: Investigating the effect of green tea extract (GTE) on the testicular damage induced by cadmium chloride CdCl2 in male rats. Design: Randomized controlled study. Animals: 40 male Wistar rats. Procedures: Rats were randomly divided into four groups: A) control group (each rat daily received pellet diet); B) GTE group each rat daily received pellet diet as well as 3 ml of 1.5 % w/v GTE, C) CdCl2 group each rat was I/P injected a single dose of 1 mg/kg CdCl2, then daily received pellet diet, and D) CdCl2+GTE group each rat was I/P injected a single dose of 1 mg/kg CdCl2 then daily received pellet diet as well as 3 ml of 1.5 % w/v GTE. After 30 days, blood samples were collected for hormonal assays (testosterone, FSH, and LH). In addition, both testes were collected; one of them was used for quantification of 17-beta hydroxysteroid dehydrogenase III (17β-HSDIII) gene expression using a real-time PCR. The other testis was used for determination of catalase and reduced glutathione; GSH, Nitric oxide (NO) and malondialdehyde (MDA) levels. Results: CdCl2 decreased serum testosterone levels and its synthesis pathway (17β-HSDIII testicular gene expression). While antioxidants catalase and GSH were reduced, oxidants MDA were enriched in the testes of CdCl2-poisoned rats. This CdCl2-promoted testicular dysfunction was corrected via the administration of GTE to male rats. Conclusion and clinical relevance: GTE could be used as a remedy for protecting against CdCl2-induced testicular damage in male rats.


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