scholarly journals Associations of the adrenomedullin gene polymorphism with prehypertension and hypertension in Lithuanian children and adolescents: a cross-sectional study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Sandrita Simonyte ◽  
Renata Kuciene ◽  
Virginija Dulskiene ◽  
Vaiva Lesauskaite
Keyword(s):  
Gene Polymorphism ◽  
Children And Adolescents ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Association betweenATP2B1andCACNB2polymorphisms and high blood pressure in a population of Lithuanian children and adolescents: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e019902 ◽  
Author(s):  
Sandrita Simonyte ◽  
Renata Kuciene ◽  
Virginija Dulskiene ◽  
Vaiva Lesauskaite
Keyword(s):  
Blood Pressure ◽  
Gene Polymorphism ◽  
Children And Adolescents ◽  
High Blood Pressure ◽  
Gene Polymorphisms ◽  
Critical Role ◽  
Cross Sectional Study ◽  
Additive Models ◽  
Sectional Study ◽  
Cross Sectional

ObjectivesRecently, genome-wide associated studies have identified several genetic loci that are associated with elevated blood pressure and could play a critical role in intracellular calcium homeostasis. The aim of this study was to assess the associations ofATP2B1rs2681472 andCACNB2rs12258967 gene polymorphisms with high blood pressure (HBP) among Lithuanian children and adolescents aged 12–15 years.Study design and participantsThis was a cross-sectional study of a randomly selected sample of 646 12–15-year-old adolescents who participated in the survey ‘The Prevalence and Risk Factors of HBP in 12–15 Year-Old Lithuanian Children and Adolescents (from November 2010 to April 2012)’. Anthropometric parameters and BP were measured. The participants with HBP were screened on two separate occasions. Subjects were genotypedATP2B1rs2681472 andCACNB2rs12258967 gene polymorphisms using real-time PCR method.ResultsThe prevalence of HBP was 36.7%, significantly higher for boys than for girls. In the multivariate analysis, after adjustment for body mass index and waist circumference, boys withCACNB2CG genotype,CACNB2GG genotype andCACNB2CG +GG genotype had higher odds of having HBP in codominant (adjusted OR (aOR)=1.92; 95% CI 1.16 to 3.18, p=0.011; and aOR=2.64; 95% CI 1.19 to 5.90, p=0.018) and in dominant (aOR=2.05; 95% CI 1.27 to 3.30, p=0.003) inheritance models. Girls carryingCACNB2CG genotype andCACNB2CG +GG genotype had increased odds of HBP in codominant (aOR=1.82; 95% CI 1.02 to 3.24, p=0.044) and in dominant (aOR=1.89; 95% CI 1.09 to 3.28, p=0.023) inheritance models. Furthermore, significant associations were found in additive models separately for boys (aOR=1.72; 95% CI 1.20 to 2.46, p=0.003) and girls (aOR=1.52; 95% CI 1.05 to 2.20, p=0.027). No significant association was found betweenATP2B1gene polymorphism and the odds of HBP.ConclusionsOur results indicate thatCACNB2gene polymorphism was significantly associated with higher odds of HBP in Lithuanian adolescents aged 12–15 years.

scholarly journals Comparing self-perceived global self-esteem and physical self-esteem among children and adolescents in Southeastern Sweden, investigated in 2000 and 2017

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Anders Raustorp ◽  
Andreas Fröberg
Keyword(s):  
Children And Adolescents ◽  
Self Esteem ◽  
Cross Sectional Study ◽  
Children And Youth ◽  
Sectional Study ◽  
Self Perception ◽  
Cross Sectional ◽  
Grade Levels ◽  
Grade 5 ◽  
Grade 8

AbstractObjectivesTo compare self-perceived global self-esteem (GSE) and physical self-esteem (PSE) among children and adolescents aged 11 and 14 years in Southeastern Sweden, investigated in 2000 and 2017.MethodsThe present study consists of two independent cross-sectional study-cohorts from Southeastern Sweden, investigated in 2000 and 2017. The same protocol, procedures, and instruments were used in 2000 and 2017. In October 2000, data for self-perceived GSE and PSE, and anthropometry were collected from 11-years old children (Grade 5) (n=74) and 14-years old adolescents (Grade 8) (n=84). In October 2017, children (n=186) and adolescents (n=140) from the same grade-levels, schools and classrooms provided data for the same variables as in 2000. GSE and PSE were assessed with the Children and Youth Physical Self-Perception Profile (CY-PSPP).ResultsSelf-perceived GSE was higher in 2017 as compared to 2000 among both 11-years old boys (p<0.001) and girls (p<0.001) and 14-years old boys (p=0.008) and girls (p<0.001). Similarly, self-perceived PSE was higher in 2017 as compared to 2000 among both 11-years old boys (p<0.001) and girls (p=0.023) and 14-years old boys (p=0.025) and girls (p=0.002).ConclusionsSelf-perceived GSE and PSE among children and adolescents aged 11 and 14 years in Southeastern Sweden were higher in 2017 as compared to 2000. These results are not in agreement with the increased psychological ill-health as being reported among children and adolescents during the last decade in Sweden.

scholarly journals Migration, family dysfunction and psychotic symptoms in children and adolescents

2005 ◽  
Vol 186 (5) ◽  
pp. 442-443 ◽  
Author(s):  
Luis R. Patino ◽  
Jean-Paul Selten ◽  
Herman van Engeland ◽  
Jan H. M. Duyx ◽  
René S. Kahn ◽  
...  
Keyword(s):  
Relative Risk ◽  
Children And Adolescents ◽  
Cross Sectional Study ◽  
Family Dysfunction ◽  
Psychotic Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
Migration History ◽  
And Migration

SummaryA cross-sectional study of 3426 referred children and adolescents showed that the presence of both migration history and family dysfunction was associated with a fourfold (95% CI 2–9) higher risk of psychotic symptoms compared with the absence of these factors. The relative risk was 2 (95% CI 1–4) for migration history only. Interaction between migration history and family dysfunction accounted for 58% (95% CI 5–91%) of those with psychotic symptoms. These results suggest a relationship between family dysfunction and migration in the development of psychosis.

scholarly journals Design of a cross-sectional study on physical fitness and physical activity in children and adolescents after burn injury

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Laurien M Disseldorp ◽  
Leonora J Mouton ◽  
Tim Takken ◽  
Marco Van Brussel ◽  
Gerard IJM Beerthuizen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Fitness ◽  
Children And Adolescents ◽  
Burn Injury ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional
Sign in / Sign up

Export Citation Format

Share Document