scholarly journals Spirulina platensis prevents oxidative stress and inflammation promoted by strength training in rats: dose-response relation study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Aline de Freitas Brito ◽  
Alexandre Sérgio Silva ◽  
Caio Victor Coutinho de Oliveira ◽  
Alesandra Araújo de Souza ◽  
Paula Benvindo Ferreira ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Strength Training ◽  
Dose Response ◽  
Spirulina Platensis

scholarly journals Spirulina Platensis Supplementation Coupled to Strength Exercise Improves Redox Balance and Reduces Intestinal Contractile Reactivity in Rat Ileum

Marine Drugs ◽  
2020 ◽  
Vol 18 (2) ◽  
pp. 89
Author(s):  
Layanne C. C. Araujo ◽  
Aline F. Brito ◽  
Iara L. L. Souza ◽  
Paula B. Ferreira ◽  
Luiz Henrique C. Vasconcelos ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Strength Training ◽  
Spirulina Platensis ◽  
Cell Damage ◽  
Redox Balance ◽  
Antioxidant Defenses ◽  
Rat Ileum ◽  
Beneficial Effects ◽  
Dpph Method ◽  
Male Wistar Rats

The blue alga Spirulina platensis has presented several pharmacological activities, highlighting its actions as an anti-inflammatory and antioxidant. In addition, there are few studies with the influence of strength training on physiological parameters, as intestinal contractility and oxidative cell damage. We evaluated the influence of S. platensis supplementation, strength training, and its association on contractile reactivity of rat ileum, as well as the balance of oxidative stress/antioxidant defenses. Methods: Male Wistar rats were divided into; sedentary (S); S + supplemented with algae at 50 (S50), 150 (S150), and 500 mg/kg (S500); trained (T); and T + supplemented (T50, T150, and T500). Contractile reactivity was analyzed by kymographs; oxidative stress on ileum by the malondialdehyde (MDA) formation; and the antioxidant capacity by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. S. platensis supplementation reduced the reactivity of rat ileum to carbachol (CCh) and KCl, while training reduced only the CCh efficacy. In addition, association potentiated the reduction on contractile reactivity. Supplementation reduced the oxidative stress and increased oxidation inhibition; training alone did not alter this parameter, however association potentiated this beneficial effect. Therefore, this study demonstrated that both supplementation and its association with strength training promote beneficial effects regarding intestinal contractile reactivity and oxidative stress, providing new insights for intestinal disorders management.

scholarly journals Supplementation with Spirulina platensis Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3763
Author(s):  
Paula Benvindo Ferreira ◽  
Anderson Fellyp Avelino Diniz ◽  
Francisco Fernandes Lacerda Júnior ◽  
Maria da Conceição Correia Silva ◽  
Glêbia Alexa Cardoso ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Strength Training ◽  
Antioxidant Capacity ◽  
Spirulina Platensis ◽  
Antioxidant Defenses ◽  
Food Supplementation ◽  
Stress Reactions ◽  
Rat Uterus ◽  
Dpph Method ◽  
And Oxidative Stress

Strength training increases systemic oxygen consumption, causing the excessive generation of reactive oxygen species, which in turn, provokes oxidative stress reactions and cellular processes that induce uterine contraction. The aim of this study was to evaluate the possible protective effect of Spirulina platensis (SP), an antioxidant blue algae, on the contractile and relaxation reactivity of rat uterus and the balance of oxidative stress/antioxidant defenses. Female Wistar rats were divided into sedentary (CG), trained (TG), and T + supplemented (TG50, TG100) groups. Reactivity was analyzed by AQCAD, oxidative stress was evaluated by the malondialdehyde (MDA) formation, and the antioxidant capacity was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Strength training increased contractile reactivity and decreased the pharmaco-mechanical component of relaxing reactivity in rat uterus. In addition, training decreased oxidation inhibition in the plasma and exercise increased oxidative stress in the uterine tissue; however, supplementation with algae prevented this effect and potentiated the increase in antioxidant capacity. Therefore, this study demonstrated that food supplementation prevents changes in reactivity and oxidative stress induced by strength training in a rat uterus, showing for the first time, that the uterus is a target for this exercise modality and antioxidant supplementation with S. platensis is an alternative means of preventing uterine dysfunction.

Dose–Response Effect of Tualang Honey on Postprandial Antioxidant Activity and Oxidative Stress in Female Athletes: A Pilot Study

2017 ◽  
Vol 23 (12) ◽  
pp. 989-995 ◽  
Author(s):  
Nur Syamsina Ahmad ◽  
Azlina Abdul Aziz ◽  
Kin Weng Kong ◽  
Mohamad Shariff A. Hamid ◽  
Jadeera Phaik Geok Cheong ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Pilot Study ◽  
Dose Response ◽  
Female Athletes ◽  
Response Effect ◽  
Dose Response Effect ◽  
Tualang Honey ◽  
And Oxidative Stress

scholarly journals Elevated Cellular Oxidative Stress in Circulating Immune Cells in Otherwise Healthy Young People Who Use Electronic Cigarettes in a Cross‐Sectional Single‐Center Study: Implications for Future Cardiovascular Risk

2020 ◽  
Vol 9 (18) ◽  
Author(s):  
Theodoros Kelesidis ◽  
Elizabeth Tran ◽  
Sara Arastoo ◽  
Karishma Lakhani ◽  
Rachel Heymans ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Young People ◽  
Dose Response ◽  
Fluorescent Probes ◽  
Immune Cell ◽  
Electronic Cigarettes ◽  
Study Groups ◽  
Cross Sectional ◽  
Premature Cardiovascular Disease ◽  
Healthy Young People

Background Tobacco cigarettes (TCs) increase oxidative stress and inflammation, both instigators of atherosclerotic cardiac disease. It is unknown if electronic cigarettes (ECs) also increase immune cell oxidative stress. We hypothesized an ordered, “dose‐response” relationship, with tobacco‐product type as “dose” (lowest in nonsmokers, intermediate in EC vapers, and highest in TC smokers), and the “response” being cellular oxidative stress (COS) in immune cell subtypes, in otherwise, healthy young people. Methods and Results Using flow cytometry and fluorescent probes, COS was determined in immune cell subtypes in 33 otherwise healthy young people: nonsmokers (n=12), EC vapers (n=12), and TC smokers (n=9). Study groups had similar baseline characteristics, including age, sex, race, and education level. A dose‐response increase in proinflammatory monocytes and lymphocytes, and their COS content among the 3 study groups was found: lowest in nonsmokers, intermediate in EC vapers, and highest in TC smokers. These findings were most striking in CD14 dim CD16 + and CD14 ++ CD16 + proinflammatory monocytes and were reproduced with 2 independent fluorescent probes of COS. Conclusions These findings portend the development of premature cardiovascular disease in otherwise healthy young people who chronically vape ECs. On the other hand, that the COS is lower in EC vapers compared with TC smokers warrants additional investigation to determine if switching to ECs may form part of a harm‐reduction strategy. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03823885.

Sign in / Sign up

Export Citation Format

Share Document