scholarly journals Acute cardiovascular health effects in a panel study of personal exposure to traffic-related air pollutants and noise in Toronto, Canada

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Rita Biel ◽  
Coraline Danieli ◽  
Maryam Shekarrizfard ◽  
Laura Minet ◽  
Michal Abrahamowicz ◽  
...  

Abstract Urban populations are often simultaneously exposed to air pollution and environmental noise, which are independently associated with cardiovascular disease. Few studies have examined acute physiologic responses to both air and noise pollution using personal exposure measures. We conducted a repeated measures panel study of air pollution and noise in 46 non-smoking adults in Toronto, Canada. Data were analyzed using linear mixed-effects models and weighted cumulative exposure modeling of recent exposure. We examined acute changes in cardiovascular health effects of personal (ultrafine particles, black carbon) and regional (PM2.5, NO2, O3, Ox) measurements of air pollution and the role of personal noise exposure as a confounder of these associations. We observed adverse changes in subclinical cardiovascular outcomes in response to both air pollution and noise, including changes in endothelial function and heart rate variability (HRV). Our findings show that personal noise exposures can confound associations for air pollutants, particularly with HRV, and that impacts of air pollution and noise on HRV occur soon after exposure. Thus, both noise and air pollution have a measurable impact on cardiovascular physiology. Noise should be considered alongside air pollution in future studies to elucidate the combined impacts of these exposures in urban environments.

2018 ◽  
Vol 2018 (1) ◽  
Author(s):  
Rita Biel ◽  
Marianne Hatzopoulou ◽  
Maryam Shekarrizfard ◽  
Laura Minet ◽  
Rick Liu ◽  
...  

2017 ◽  
Vol 68 (4) ◽  
pp. 841-846
Author(s):  
Hai-Ying Liu ◽  
Daniel Dunea ◽  
Mihaela Oprea ◽  
Tom Savu ◽  
Stefania Iordache

This paper presents the approach used to develop the information chain required to reach the objectives of the EEA Grants� RokidAIR project in two Romanian cities i.e., Targoviste and Ploiesti. It describes the PM2.5 monitoring infrastructure and architecture to the web-based GIS platform, the early warning system and the decision support system, and finally, the linking of air pollution to health effects in children. In addition, it shows the analysis performance of the designed system to process the collected time series from various data sources using the benzene concentrations monitored in Ploiesti. Moreover, this paper suggests that biomarkers, mobile technologies, and Citizens� Observatories are potential perspectives to improve data coverage by the provision of near-real-time air quality maps, and provide personal exposure and health assessment results, enabling the citizens� engagement and behavioural change. This paper also addresses new fields in nature-based solutions to improve air quality, and studies on air pollution and its mental health effects in the urban areas of Romania.


Atmosphere ◽  
2020 ◽  
Vol 11 (5) ◽  
pp. 496
Author(s):  
Kyung Hwan Kim ◽  
Kyung-Hwan Kwak ◽  
Jae Young Lee ◽  
Sung Ho Woo ◽  
Jong Bum Kim ◽  
...  

In this work, a 2-D gridded air pollution map with a high resolution of 50 × 50 m2 was proposed to help the exposure assessment studies focusing on the association between air pollutants and their health effects. To establish a reliable air pollution map in a 2 × 2 km2 urban area, a mobile monitoring procedure and a data process were developed. Among the various vehicle-related air pollutants, the particle-bound polycyclic aromatic hydrocarbon (pPAH) was chosen as a sensitive indicator. The average pPAH concentration on major roads (293.1 ng/m3) was found to be 35 times higher than that at a background location (8.4 ng/m3). Based on the cell-based pPAH concentrations, the 50 × 50 m2 cells in the air pollution map were categorized into five pollution levels. The higher air pollution levels were generally shown by the cells close to the major traffic emission points. The proposed map can be used to make various policies regarding land use and traffic flow control in urban areas. Estimation of the personal exposure level to air pollutants is possible at a reliable location using the highly resolved 2-D gridded air pollution map in exposure assessment studies.


2008 ◽  
Vol 115 (6) ◽  
pp. 175-187 ◽  
Author(s):  
Robert D. Brook

Air pollution is a heterogeneous mixture of gases, liquids and PM (particulate matter). In the modern urban world, PM is principally derived from fossil fuel combustion with individual constituents varying in size from a few nanometres to 10 μm in diameter. In addition to the ambient concentration, the pollution source and chemical composition may play roles in determining the biological toxicity and subsequent health effects. Nevertheless, studies from across the world have consistently shown that both short- and long-term exposures to PM are associated with a host of cardiovascular diseases, including myocardial ischaemia and infarctions, heart failure, arrhythmias, strokes and increased cardiovascular mortality. Evidence from cellular/toxicological experiments, controlled animal and human exposures and human panel studies have demonstrated several mechanisms by which particle exposure may both trigger acute events as well as prompt the chronic development of cardiovascular diseases. PM inhaled into the pulmonary tree may instigate remote cardiovascular health effects via three general pathways: instigation of systemic inflammation and/or oxidative stress, alterations in autonomic balance, and potentially by direct actions upon the vasculature of particle constituents capable of reaching the systemic circulation. In turn, these responses have been shown to trigger acute arterial vasoconstriction, endothelial dysfunction, arrhythmias and pro-coagulant/thrombotic actions. Finally, long-term exposure has been shown to enhance the chronic genesis of atherosclerosis. Although the risk to one individual at any single time point is small, given the prodigious number of people continuously exposed, PM air pollution imparts a tremendous burden to the global public health, ranking it as the 13th leading cause of morality (approx. 800000 annual deaths).


Author(s):  
Mark R Miller ◽  
David E Newby

Abstract The cardiovascular effects of inhaled particle matter (PM) are responsible for a substantial morbidity and mortality attributed to air pollution. Ultrafine particles, like those in diesel exhaust emissions, are a major source of nanoparticles in urban environments, and it is these particles that have the capacity to induce the most significant health effects. Research has shown that diesel exhaust exposure can have many detrimental effects on the cardiovascular system both acutely and chronically. This review provides an overview of the cardiovascular effects on PM in air pollution, with an emphasis on ultrafine particles in vehicle exhaust. We consider the biological mechanisms underlying these cardiovascular effects of PM and postulate that cardiovascular dysfunction may be implicated in the effects of PM in other organ systems. The employment of multiple strategies to tackle air pollution, and especially ultrafine particles from vehicles, is likely to be accompanied by improvements in cardiovascular health.


Author(s):  
Maria-Viola Martikainen ◽  
Päivi Aakko-Saksa ◽  
Lenie van den Broek ◽  
Flemming R. Cassee ◽  
Roxana O. Carare ◽  
...  

The adverse effects of air pollutants on the respiratory and cardiovascular systems are unquestionable. However, in recent years, indications of effects beyond these organ systems have become more evident. Traffic-related air pollution has been linked with neurological diseases, exacerbated cognitive dysfunction, and Alzheimer’s disease. However, the exact air pollutant compositions and exposure scenarios leading to these adverse health effects are not known. Although several components of air pollution may be at play, recent experimental studies point to a key role of ultrafine particles (UFPs). While the importance of UFPs has been recognized, almost nothing is known about the smallest fraction of UFPs, and only >23 nm emissions are regulated in the EU. Moreover, the role of the semivolatile fraction of the emissions has been neglected. The Transport-Derived Ultrafines and the Brain Effects (TUBE) project will increase knowledge on harmful ultrafine air pollutants, as well as semivolatile compounds related to adverse health effects. By including all the major current combustion and emission control technologies, the TUBE project aims to provide new information on the adverse health effects of current traffic, as well as information for decision makers to develop more effective emission legislation. Most importantly, the TUBE project will include adverse health effects beyond the respiratory system; TUBE will assess how air pollution affects the brain and how air pollution particles might be removed from the brain. The purpose of this report is to describe the TUBE project, its background, and its goals.


2013 ◽  
Vol 15 (2) ◽  
pp. 209-217 ◽  

This study offers a combined analysis of personal exposure to noise and air pollution within the metropolitan centre of Thessaloniki, Greece. The area is selected on the grounds that it is considered as one of the most polluted cities in Europe, especially with respect to air pollution. An extensive survey has been designed to provide detailed information on CO and VOC concentrations and noise pollution levels in the main modes of transport and along heavy traffic routes inside the core of the urban area under consideration. Air pollution and noise measurements were performed simultaneously along several commuting routes, during morning and evening rush hours. Personal portable devices were used. The results highlight the magnitude of air and noise urban scale personal exposure, since they depict a considerable environmental burden for the citizens of Thessaloniki, especially for VOCs and noise pollution levels. Furthermore, they provide, for the first time, a combined exposure assessment to these environmental pollutants for Thessaloniki and in this sense they are of importance for local public authorities and decision makers. The material herein points out the importance of micro-environmental monitoring and the necessity of considering environmental pollution in urban areas in a more holistic way.


Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Sarah Singh ◽  
Courtney Pilkerton ◽  
Adam Christian ◽  
Thomas K Bias ◽  
Stephanie J Frisbee

BACKGROUND: Although the link between air pollution and cardiovascular disease has been controversial in recent decades, it remains a top global health concern. Most studies have assessed only the relationship between pollutant concentrations and morbidity or mortality in populous cities. In this study, we investigated the association of long term exposure to major air pollutants with current cardiovascular health. This outcome was a measure of health rather than disease, as measured by the Cardiovascular Health Index (CVHI) developed by the American Heart Association. METHODS: We analyzed 2011 data from 3007 counties across the US using Behavioral Risk Factor Surveillance System and Area Health Resources File. Air Quality Index (AQI) for five major pollutants from 2001-2011; Ozone, Sulfur dioxide and Carbon monoxide and Fine particulate matter (aerodynamic diameter of 10 and ≤2.5 μm) were obtained from the EPA Air Quality System database. Categories were based on the 11-year average pollutant AQI level and using Jenks optimization method; persistently good, variant and persistently bad. Associations between categories and the mean CVHI were evaluated using Poisson regression models adjusting for age, sex, race/ethnicity and socioeconomic status at the individual and population level. RESULTS: PM2.5 was most frequently measured (938 counties) and carbon monoxide least frequently (224 counties). Correlations between pollutants were moderate and significant (p<0.0001), ranging from r=0.30 between CO and Oz to r=0.52 between SD and PM2.5. Four pollutants had 11-year average AQI levels significantly associated with increased mean CVHI score of individuals. Living in a county categorized as ‘persistently good’ or ‘variant’ AQI levels for ozone is significantly associated with an estimated 3% increase in CVHI (95% CI 0.1% - 5.0%) as compared to living in a county of ‘persistently bad’ AQI levels. In addition, living in a county of only ‘persistently good’ AQI levels for PM2.5 is significantly associated with an estimated 5% increase in CVHI (95% CI 3% - 9%) as compared to living in a county of ‘persistently bad’ AQI levels. Inverse relationships existed for both PM10 and carbon monoxide. CONCLUSIONS: It is difficult to tease apart the independent effects of individual air pollutants on health as humans are exposed to a mixture of gases. However we have shown that at the individual level, there is an association between long term exposure to air pollution and its effects on current cardiovascular health. Further research is needed to determine whether these effects exist at varying levels of subject characteristics.


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