scholarly journals Deep learning-based thin-section MRI reconstruction improves tumour detection and delineation in pre- and post-treatment pituitary adenoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Da Hyun Lee ◽  
Ji Eun Park ◽  
Yeo Kyung Nam ◽  
Joonsung Lee ◽  
Seonok Kim ◽  
...  
Keyword(s):  
Deep Learning ◽  
Pituitary Adenoma ◽  
Thin Section ◽  
Signal To Noise Ratio ◽  
Imaging Protocol ◽  
Normal Pituitary Gland ◽  
Significant Difference ◽  
Mri Reconstruction ◽  
Magnetic Resonance Imaging Mri ◽  
Higher Sensitivity

AbstractEven a tiny functioning pituitary adenoma could cause symptoms; hence, accurate diagnosis and treatment are crucial for management. However, it is difficult to diagnose a small pituitary adenoma using conventional MR sequence. Deep learning-based reconstruction (DLR) using magnetic resonance imaging (MRI) enables high-resolution thin-section imaging with noise reduction. In the present single-institution retrospective study of 201 patients, conducted between August 2019 and October 2020, we compared the performance of 1 mm DLR MRI with that of 3 mm routine MRI, using a combined imaging protocol to detect and delineate pituitary adenoma. Four readers assessed the adenomas in a pairwise fashion, and diagnostic performance and image preferences were compared between inexperienced and experienced readers. The signal-to-noise ratio (SNR) was quantitatively assessed. New detection of adenoma, achieved using 1 mm DLR MRI, was not visualised using 3 mm routine MRI (overall: 6.5% [13/201]). There was no significant difference depending on the experience of the readers in new detections. Readers preferred 1 mm DLR MRI over 3 mm routine MRI (overall superiority 56%) to delineate normal pituitary stalk and gland, with inexperienced readers more preferred 1 mm DLR MRI than experienced readers. The SNR of 1 mm DLR MRI was 1.25-fold higher than that of the 3 mm routine MRI. In conclusion, the 1 mm DLR MRI achieved higher sensitivity in the detection of pituitary adenoma and provided better delineation of normal pituitary gland than 3 mm routine MRI.

scholarly journals Validation of Deep Learning-Based Artifact Correction on Synthetic FLAIR Images in a Different Scanning Environment

2020 ◽  
Vol 9 (2) ◽  
pp. 364 ◽  
Author(s):  
Kyeong Hwa Ryu ◽  
Hye Jin Baek ◽  
Sung-Min Gho ◽  
Kanghyun Ryu ◽  
Dong-Hyun Kim ◽  
...  
Keyword(s):  
Deep Learning ◽  
Periventricular White Matter ◽  
Artifact Correction ◽  
Significant Difference ◽  
Fluid Attenuated Inversion Recovery ◽  
Quantitative Analyses ◽  
Promising Solution ◽  
Test Sets ◽  
Magnetic Resonance Imaging Mri

We investigated the capability of a trained deep learning (DL) model with a convolutional neural network (CNN) in a different scanning environment in terms of ameliorating the quality of synthetic fluid-attenuated inversion recovery (FLAIR) images. The acquired data of 319 patients obtained from the retrospective review were used as test sets for the already trained DL model to correct the synthetic FLAIR images. Quantitative analyses were performed for native synthetic FLAIR and DL-FLAIR images against conventional FLAIR images. Two neuroradiologists assessed the quality and artifact degree of the native synthetic FLAIR and DL-FLAIR images. The quantitative parameters showed significant improvement on DL-FLAIR in all individual tissue segments and total intracranial tissues than on the native synthetic FLAIR (p < 0.0001). DL-FLAIR images showed improved image quality with fewer artifacts than the native synthetic FLAIR images (p < 0.0001). There was no significant difference in the preservation of the periventricular white matter hyperintensities and lesion conspicuity between the two FLAIR image sets (p = 0.217). The quality of synthetic FLAIR images was improved through artifact correction using the trained DL model on a different scan environment. DL-based correction can be a promising solution for ameliorating the quality of synthetic FLAIR images to broaden the clinical use of synthetic magnetic resonance imaging (MRI).

scholarly journals Deep Learning Image Processing Enables 40% Faster Spinal MR Scans Which Match or Exceed Quality of Standard of Care

2021 ◽  
Author(s):  
S. Bash ◽  
B. Johnson ◽  
W. Gibbs ◽  
T. Zhang ◽  
A. Shankaranarayanan ◽  
...  
Keyword(s):  
Deep Learning ◽  
Signal To Noise Ratio ◽  
Similarity Index ◽  
Standard Of Care ◽  
Structural Similarity ◽  
Image Features ◽  
Scan Time ◽  
Magnetic Resonance Imaging Mri ◽  
Display Order ◽  
Spine Mri

Abstract Objective This prospective multicenter multireader study evaluated the performance of 40% scan-time reduced spinal magnetic resonance imaging (MRI) reconstructed with deep learning (DL). Methods A total of 61 patients underwent standard of care (SOC) and accelerated (FAST) spine MRI. DL was used to enhance the accelerated set (FAST-DL). Three neuroradiologists were presented with paired side-by-side datasets (666 series). Datasets were blinded and randomized in sequence and left-right display order. Image features were preference rated. Structural similarity index (SSIM) and per pixel L1 was assessed for the image sets pre and post DL-enhancement as a quantitative assessment of image integrity impact. Results FAST-DL was qualitatively better than SOC for perceived signal-to-noise ratio (SNR) and artifacts and equivalent for other features. Quantitative SSIM was high, supporting the absence of image corruption by DL processing. Conclusion DL enables 40% spine MRI scan time reduction while maintaining diagnostic integrity and image quality with perceived benefits in SNR and artifact reduction, suggesting potential for clinical practice utility.

scholarly journals Contact endoscopy as a novel technique for intra-operative identification of normal pituitary gland and adenoma

2022 ◽  
Vol 6 (1) ◽  
pp. V17
Keyword(s):  
Pituitary Adenoma ◽  
Pituitary Gland ◽  
Thin Section ◽  
Tumor Resection ◽  
Noninvasive Technique ◽  
Endoscopic Endonasal ◽  
Novel Technique ◽  
Normal Gland ◽  
Normal Pituitary Gland

Intraoperative distinction of pituitary adenoma from normal gland is critical in maximizing tumor resection without compromising pituitary function. Contact endoscopy provides a noninvasive technique that allows for real-time in vivo visualization of differences in tissue vascularity. Two illustrative cases of endoscopic endonasal approaches (EEAs) for resection of pituitary adenoma illustrate the use of contact endoscopy in identifying tumor from gland and differentiating a thin section of normal gland draped over the underlying tumor, thereby allowing for safe extracapsular tumor resection. Contact endoscopy may be used as an adjunct for intraoperative, in vivo differentiation of pituitary gland and adenoma. The video can be found here: https://stream.cadmore.media/r10.3171/2021.10.FOCVID21199

scholarly journals A review on deep learning MRI reconstruction without fully sampled k-space

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Gushan Zeng ◽  
Yi Guo ◽  
Jiaying Zhan ◽  
Zi Wang ◽  
Zongying Lai ◽  
...  
Keyword(s):  
Deep Learning ◽  
Parallel Imaging ◽  
Prior Information ◽  
Clinical Medicine ◽  
Ground Truth ◽  
Acquisition Time ◽  
Sampled Data ◽  
Mri Reconstruction ◽  
Magnetic Resonance Imaging Mri ◽  
Space Data

Abstract Background Magnetic resonance imaging (MRI) is an effective auxiliary diagnostic method in clinical medicine, but it has always suffered from the problem of long acquisition time. Compressed sensing and parallel imaging are two common techniques to accelerate MRI reconstruction. Recently, deep learning provides a new direction for MRI, while most of them require a large number of data pairs for training. However, there are many scenarios where fully sampled k-space data cannot be obtained, which will seriously hinder the application of supervised learning. Therefore, deep learning without fully sampled data is indispensable. Main text In this review, we first introduce the forward model of MRI as a classic inverse problem, and briefly discuss the connection of traditional iterative methods to deep learning. Next, we will explain how to train reconstruction network without fully sampled data from the perspective of obtaining prior information. Conclusion Although the reviewed methods are used for MRI reconstruction, they can also be extended to other areas where ground-truth is not available. Furthermore, we may anticipate that the combination of traditional methods and deep learning will produce better reconstruction results.

ANALISIS SENSITIVITAS VIDEO MPEG-4 BERDASARKAN STRUKTUR FRAME PADA TRANSMISI DVB-T

2020 ◽  
Vol 25 (2) ◽  
pp. 86-97
Author(s):  
Sandy Suryo Prayogo ◽  
Tubagus Maulana Kusuma
Keyword(s):  
Deep Learning ◽  
Bit Error Rate ◽  
Error Rate ◽  
Signal To Noise Ratio ◽  
Similarity Index ◽  
Structural Similarity ◽  
Signal To Noise ◽  
Structural Similarity Index ◽  
Noise Ratio

DVB merupakan standar transmisi televisi digital yang paling banyak digunakan saat ini. Unsur terpenting dari suatu proses transmisi adalah kualitas gambar dari video yang diterima setelah melalui proses transimisi tersebut. Banyak faktor yang dapat mempengaruhi kualitas dari suatu gambar, salah satunya adalah struktur frame dari video. Pada tulisan ini dilakukan pengujian sensitifitas video MPEG-4 berdasarkan struktur frame pada transmisi DVB-T. Pengujian dilakukan menggunakan simulasi matlab dan simulink. Digunakan juga ffmpeg untuk menyediakan format dan pengaturan video akan disimulasikan. Variabel yang diubah dari video adalah bitrate dan juga group-of-pictures (GOP), sedangkan variabel yang diubah dari transmisi DVB-T adalah signal-to-noise-ratio (SNR) pada kanal AWGN di antara pengirim (Tx) dan penerima (Rx). Hasil yang diperoleh dari percobaan berupa kualitas rata-rata gambar pada video yang diukur menggunakan metode pengukuran structural-similarity-index (SSIM). Dilakukan juga pengukuran terhadap jumlah bit-error-rate BER pada bitstream DVB-T. Percobaan yang dilakukan dapat menunjukkan seberapa besar sensitifitas bitrate dan GOP dari video pada transmisi DVB-T dengan kesimpulan semakin besar bitrate maka akan semakin buruk nilai kualitas gambarnya, dan semakin kecil nilai GOP maka akan semakin baik nilai kualitasnya. Penilitian diharapkan dapat dikembangkan menggunakan deep learning untuk memperoleh frame struktur yang tepat di kondisi-kondisi tertentu dalam proses transmisi televisi digital.

Frame-Level Signal-to-Noise Ratio Estimation Using Deep Learning

2020 ◽  
Author(s):  
Hao Li ◽  
DeLiang Wang ◽  
Xueliang Zhang ◽  
Guanglai Gao
Keyword(s):  
Deep Learning ◽  
Signal To Noise Ratio ◽  
Ratio Estimation ◽  
Signal To Noise ◽  
Noise Ratio

Systematic Analysis and Review of Magnetic Resonance Imaging (MRI) Reconstruction Techniques

2021 ◽  
Vol 16 ◽  
Author(s):  
Penta Anil Kumar ◽  
R. Gunasundari ◽  
R. Aarthi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Optimization Technique ◽  
Motion Artifacts ◽  
Reconstruction Technique ◽  
Resonance Imaging ◽  
Research Gaps ◽  
Conventional Mri ◽  
Mri Reconstruction ◽  
Magnetic Resonance Imaging Mri

Background: Magnetic Resonance Imaging (MRI) plays an important role in the field of medical diagnostic imaging as it poses non-invasive acquisition and high soft-tissue contrast. However, the huge time is needed for the MRI scanning process that results in motion artifacts, degrades image quality, misinterpretation of data, and may cause uncomfortable to the patient. Thus, the main goal of MRI research is to accelerate data acquisition processing without affecting the quality of the image. Introduction: This paper presents a survey based on distinct conventional MRI reconstruction methodologies. In addition, a novel MRI reconstruction strategy is proposed based on weighted Compressive Sensing (CS), Penalty-aided minimization function, and Meta-heuristic optimization technique. Methods: An illustrative analysis is done concerning adapted methods, datasets used, execution tools, performance measures, and values of evaluation metrics. Moreover, the issues of existing methods and the research gaps considering conventional MRI reconstruction schemes are elaborated to obtain improved contribution for devising significant MRI reconstruction techniques. Results: The proposed method will reduce conventional aliasing artifacts problems, may attain lower Mean Square Error (MSE), higher Peak Signal-to-Noise Ratio (PSNR), and Structural SIMilarity (SSIM) index. Conclusion: The issues of existing methods and the research gaps considering conventional MRI reconstruction schemes are elaborated to devising an improved significant MRI reconstruction technique.

An Algorithm Combining Analysis-based Blind Compressed Sensing and Nonlocal Low-rank Constraints for MRI Reconstruction

2019 ◽  
Vol 15 (3) ◽  
pp. 281-291 ◽  
Author(s):  
Mei Sun ◽  
Jinxu Tao ◽  
Zhongfu Ye ◽  
Bensheng Qiu ◽  
Jinzhang Xu ◽  
...  
Keyword(s):  
Compressed Sensing ◽  
Signal Reconstruction ◽  
Low Rank ◽  
Mr Images ◽  
Scanning Time ◽  
Previous State ◽  
Rank Approximation ◽  
Mri Reconstruction ◽  
Magnetic Resonance Imaging Mri ◽  
Rank Constraints

Background: In order to overcome the limitation of long scanning time, compressive sensing (CS) technology exploits the sparsity of image in some transform domain to reduce the amount of acquired data. Therefore, CS has been widely used in magnetic resonance imaging (MRI) reconstruction. </P><P> Discussion: Blind compressed sensing enables to recover the image successfully from highly under- sampled measurements, because of the data-driven adaption of the unknown transform basis priori. Moreover, analysis-based blind compressed sensing often leads to more efficient signal reconstruction with less time than synthesis-based blind compressed sensing. Recently, some experiments have shown that nonlocal low-rank property has the ability to preserve the details of the image for MRI reconstruction. Methods: Here, we focus on analysis-based blind compressed sensing, and combine it with additional nonlocal low-rank constraint to achieve better MR images from fewer measurements. Instead of nuclear norm, we exploit non-convex Schatten p-functionals for the rank approximation. </P><P> Results & Conclusion: Simulation results indicate that the proposed approach performs better than the previous state-of-the-art algorithms.

scholarly journals A deep learning method for automatic segmentation of the bony orbit in MRI and CT images

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jared Hamwood ◽  
Beat Schmutz ◽  
Michael J. Collins ◽  
Mark C. Allenby ◽  
David Alonso-Caneiro
Keyword(s):  
Deep Learning ◽  
Human Performance ◽  
Automatic Segmentation ◽  
Ct Images ◽  
Human Observer ◽  
In Series ◽  
Magnetic Resonance Imaging Mri ◽  
High Degree ◽  
Orbital Region ◽  
Ct And Mri

AbstractThis paper proposes a fully automatic method to segment the inner boundary of the bony orbit in two different image modalities: magnetic resonance imaging (MRI) and computed tomography (CT). The method, based on a deep learning architecture, uses two fully convolutional neural networks in series followed by a graph-search method to generate a boundary for the orbit. When compared to human performance for segmentation of both CT and MRI data, the proposed method achieves high Dice coefficients on both orbit and background, with scores of 0.813 and 0.975 in CT images and 0.930 and 0.995 in MRI images, showing a high degree of agreement with a manual segmentation by a human expert. Given the volumetric characteristics of these imaging modalities and the complexity and time-consuming nature of the segmentation of the orbital region in the human skull, it is often impractical to manually segment these images. Thus, the proposed method provides a valid clinical and research tool that performs similarly to the human observer.

Endoscopic prediction of submucosal invasion in Barrett’s cancer with the use of Artificial Intelligence: A pilot Study

Endoscopy ◽  
2020 ◽  
Author(s):  
Alanna Ebigbo ◽  
Robert Mendel ◽  
Tobias Rückert ◽  
Laurin Schuster ◽  
Andreas Probst ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Deep Learning ◽  
Pilot Study ◽  
White Light ◽  
Submucosal Invasion ◽  
Learning System ◽  
Endoscopic Images ◽  
Barrett’S Cancer ◽  
Significant Difference ◽  
Sensitivity Specificity

Background and aims: The accurate differentiation between T1a and T1b Barrett’s cancer has both therapeutic and prognostic implications but is challenging even for experienced physicians. We trained an Artificial Intelligence (AI) system on the basis of deep artificial neural networks (deep learning) to differentiate between T1a and T1b Barrett’s cancer white-light images. Methods: Endoscopic images from three tertiary care centres in Germany were collected retrospectively. A deep learning system was trained and tested using the principles of cross-validation. A total of 230 white-light endoscopic images (108 T1a and 122 T1b) was evaluated with the AI-system. For comparison, the images were also classified by experts specialized in endoscopic diagnosis and treatment of Barrett’s cancer. Results: The sensitivity, specificity, F1 and accuracy of the AI-system in the differentiation between T1a and T1b cancer lesions was 0.77, 0.64, 0.73 and 0.71, respectively. There was no statistically significant difference between the performance of the AI-system and that of human experts with sensitivity, specificity, F1 and accuracy of 0.63, 0.78, 0.67 and 0.70 respectively. Conclusion: This pilot study demonstrates the first multicenter application of an AI-based system in the prediction of submucosal invasion in endoscopic images of Barrett’s cancer. AI scored equal to international experts in the field, but more work is necessary to improve the system and apply it to video sequences and in a real-life setting. Nevertheless, the correct prediction of submucosal invasion in Barret´s cancer remains challenging for both experts and AI.

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