scholarly journals Serum sodium variation is a major determinant of peridialytic blood pressure trends in haemodialysis outpatients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
David A. Jaques ◽  
Andrew Davenport

AbstractIntradialytic hypotension (IDH) and peridialytic blood pressure (BP) trends are associated with morbidity and mortality in haemodialysis (HD) patients. We aimed to characterise the respective influence of volume status and small solutes variation on peridialytic systolic BP (SBP) trends during HD. We retrospectively analysed the relative peridialytic SBP decrease in 647 prevalent outpatients attending for their mid-week session with corresponding pre- and post-HD bioelectrical impedance analysis. Mean SBP decreased by 10.5 ± 23.6 mmHg. Factors positively associated with the relative decrease in SBP were: serum sodium (Na) decrease, body mass index, serum albumin, dialysis vintage, ultrafiltration rate and urea Kt/V (p < 0.05 for all). Antihypertensive medications and higher dialysate calcium were negatively associated with the relative decrease in SBP (p < 0.05 for both). Age had a quadratic relationship with SBP trends (p < 0.05). Pre-HD volume status measured by extracellular to total body water ratio was not associated with SBP variation (p = 0.216). Peridialytic SBP trends represent a continuum with serum Na variation being a major determinant while volume status has negligible influence. Middle-aged and overweight patients are particularly prone to SBP decline. Tailoring Na and calcium dialysate concentrations could influence haemodynamic stability during HD and improve patient experience and outcomes.

2015 ◽  
Vol 12 (C) ◽  
pp. 20
Author(s):  
Monika Latka ◽  
Dorota Drozdz* ◽  
Tomasz Drozdz ◽  
Kinga Wojtowicz ◽  
Przemko Kwinta ◽  
...  

2014 ◽  
Vol 28 (4) ◽  
pp. 553-560 ◽  
Author(s):  
Marcelo Custódio Rubira ◽  
Ana Paula Fernandes de Angelis Rubira ◽  
Lucas De Angelis Rubira ◽  
Milton Carlos Martins Lima ◽  
Roberto Jorge da Silva Franco ◽  
...  

Body composition has fundamental importance in the quality of life and is a powerful predictor of mortality and morbidity in humans. The identification and monitoring of the amount of body fat have been receiving special attention in aspects related to health promotion, not just for its actions in the prevention and in the control of cardiovascular diseases but also for their induction and association with risk factors, especially in the plasmatic lipid levels and arterial pressure. It was investigated the relationship between body mass index (BMI) and body fat percentage (%BF) by bioelectrical impedance analysis (BIA) with the blood pressure levels (systolic and diastolic) and serum lipids (TC, HDL-c, LDL-c, VLDL-c, TG). In a group of fifty seven women (aged 18 to 26 years old ), obesity was detected in 5 and 19 women by BMI (≥ 30 kg/m2) and %BF (≥ 30%), respectively. BMI and % BF were positively correlated with blood pressure (systolic and diastolic), and highly significant in the obese group by %BF. Moreover, BMI and % BF were significantly correlated with all lipids and lipoprotein fractions VLDL-c and triglyceride, respectively. These results suggest that %BF is a good indicator of “occult obesity” in subjects with normal body mass index. The associated use of BMI and %BF to better evaluate obesity may improve the study of blood pressure levels and serum lipid changes that are commonly associated with obesity.


2020 ◽  
Vol 51 (8) ◽  
pp. 589-612 ◽  
Author(s):  
Maria-Eleni Alexandrou ◽  
Olga Balafa ◽  
Pantelis Sarafidis

Background: The majority of patients undergoing peritoneal dialysis (PD) suffer from volume overload and this overhydration is associated with increased mortality. Thus, optimal assessment of volume status in PD is an issue of paramount importance. Patient symptoms and physical signs are often unreliable indexes of true hydration status. Summary: Over the past decades, a quest for a valid, reproducible, and easily applicable technique to assess hydration status is taking place. Among existing techniques, inferior vena cava diameter measurements with echocardiography and natriuretic peptides such as brain natriuretic peptide and N-terminal pro-B-type natriuretic peptide were not extensively examined in PD populations; while having certain advantages, their interpretation are complicated by the underlying cardiac status and are not widely available. Bioelectrical impedance analysis (BIA) techniques are the most studied tool assessing volume overload in PD. Volume overload assessed with BIA has been associated with technique failure and increased mortality in observational studies, but the results of randomized trials on the value of BIA-based strategies to improve volume-related outcomes are contradictory. Lung ultrasound (US) is a recent technique with the ability to identify volume excess in the critical lung area. Preliminary evidence in PD showed that B-lines from lung US correlate with echocardiographic parameters but not with BIA measurements. This review presents the methods currently used to assess fluid status in PD patients and discusses existing data on their validity, applicability, limitations, and associations with intermediate and hard outcomes in this population. Key Message: No method has proved its value as an intervening tool affecting cardiovascular events, technique, and overall survival in PD patients. As BIA and lung US estimate fluid overload in different compartments of the body, they can be complementary tools for volume status assessment.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yoon Ji Chung ◽  
Eun Young Kim

AbstractWe determined the relationship between changes in bioelectrical impedance analysis (BIA) parameters and response of critically ill patients to fluid therapy during early postoperative period. Associations between BIA values indicating volume status of postoperative patient and clinical outcomes were also evaluated. From May 2019 to April 2020, patients who were admitted to the surgical intensive care unit (SICU) of our institution at more than 48 h after surgery were enrolled. Volume status was measured with a portable BIA device every morning for five days from SICU admission. Overhydration was defined as the case where extracellular water (ECW) ratio > 0.390 measured by BIA. Participants were daily classified into an overhydration or a normohydration group. The relationship between daily hydration status and postoperative outcome was evaluated. Most of the 190 participants showed the overhydration status in the first 48 h after surgery. The overhydration status on day 3 was significant predictor of postoperative morbidities (OR 1.182) and in-hospital mortality (OR 2.040). SOFA score was significant factor of postoperative morbidities (OR 1.163) and in-hospital mortality (OR 3.151) except for the overhydration status on day 3. Cut-off values of overhydration status by ECW ratio at day 3 for predicting postoperative morbidities and in-hospital mortality were > 0.3985 and > 0.4145, respectively. BIA would be a useful and convenient tool to assess the volume status of patients requiring intensive fluid resuscitation in early postoperative period. Overhydration status by ECW ratio on postoperative day 3 needs careful monitoring and appropriate interventions to improve clinical outcomes.


Author(s):  
D. Takagi ◽  
M. Kageyama ◽  
S. Kojima ◽  
Y. Nishida

Background: Little is known about how fat mass and muscle mass in different parts of the body (e.g., appendages, trunk) using bioelectrical impedance analysis influences resting blood pressure in older adults. Objective: The purpose of the study was to clarify the association between resting blood pressure and muscle mass and fat mass in older adults using bioelectrical impedance analysis. Design: A cross-sectional study. Settings: A sample living independently in the community. Participants: The subjects were older adults between the ages of 65 and 85 years (n = 100). Measurements: Systolic, diastolic and mean arterial pressure was measured using an automatic hemodynamometer, and bioelectrical impedance analysis was used to estimate muscle mass and fat mass. Results: A positive correlation was observed between total fat mass, left and right arm fat mass, trunk fat mass, and left and right leg fat mass and resting systolic, diastolic and mean arterial pressure (p < 0.05), but this was not observed with any muscle mass (p > 0.05). In a multiple regression analysis adjusted for sex, systolic, diastolic and mean arterial pressure were independently predicted by total fat mass, left and right arm fat mass, trunk fat mass, and left and right leg fat mass (p < 0.05). Conclusions: These findings suggest that total, appendicular, and trunk fat mass, measured using bioelectrical impedance analysis, could aid in detecting the factors that increase blood pressure in clinical settings and even in daily life, thereby helping in controlling blood pressure.


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