scholarly journals Role and effectiveness of complex and supervised rehabilitation on overall and hand function in systemic sclerosis patients—one-year follow-up study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Michał Waszczykowski ◽  
Bożena Dziankowska-Bartkowiak ◽  
Michał Podgórski ◽  
Jarosław Fabiś ◽  
Arleta Waszczykowska
Keyword(s):  
Systemic Sclerosis ◽  
Hand Function ◽  
Exercise Program ◽  
Rehabilitation Program ◽  
Long Term Results ◽  
Home Exercise ◽  
Control Group ◽  
Study Group

AbstractThe aim of this study was to estimate the long-term results of complex and supervised rehabilitation of the hands in systemic sclerosis (SSc) patients. Fifty-one patients were enrolled in this study: 27 patients (study group) were treated with a 4-week complex, supervised rehabilitation protocol. The control group of 24 patients was prescribed a home exercise program alone. Both groups were evaluated at baseline and after 1-, 3-, 6-, and 12-months of follow-up with the Disability of the Arm, Shoulder and Hand Questionnaire (DAHS) as the primary outcome, pain (VAS—visual analog scale), Cochin Hand Function Scale (CHFS), Health Assessment Questionnaire Disability Index (HAQ-DI), Scleroderma-HAQ (SHAQ), range of motion (d-FTP—delta finger to palm, Kapandji finger opposition test) and hand grip and pinch as the secondary outcomes. Only the study group showed significant improvements in the DASH, VAS, CHFS and SHAQ after 1, 3 and 6 months of follow-up (P = 0.0001). Additionally, moderate correlations between the DASH, CHFS and SHAQ (R = 0.7203; R = 0.6788; P = 0.0001) were found. Complex, supervised rehabilitation improves hand and overall function in SSc patients up to 6 months after the treatment but not in the long term. The regular repetition of this rehabilitation program should be recommended every 3–6 months to maintain better hand and overall function.

Effects of a motor imagery-based exercise protocol on chronic pain and emotional distress in patients with fibromyalgia syndrome: A pilot study

2021 ◽  
pp. 1-10
Author(s):  
Teresa Paolucci ◽  
Francesco Agostini ◽  
Massimiliano Mangone ◽  
Andrea Torquati ◽  
Simona Scienza ◽  
...  
Keyword(s):  
Motor Imagery ◽  
Fibromyalgia Syndrome ◽  
Coping Behavior ◽  
Exercise Program ◽  
Rehabilitation Program ◽  
The Body ◽  
Control Group ◽  
Exercise Protocol ◽  
And Coping

BACKGROUND: Fibromyalgia (FM) is a chronic condition characterized by widespread muscular or musculoskeletal pain of at least 3 months’ duration, occurring above and below the waist, on both sides of the body. OBJECTIVE: The aim of this study was to evaluate the effectiveness of a rehabilitation program based on motor imagery versus a conventional exercise program in FM in terms of pain, functional and psychological outcomes. METHODS: Twenty-nine female subjects were randomly assigned to a group receiving motor imagery-based rehabilitation (MIG) or to a control group (CG) performing conventional rehabilitation. Outcome assessments were performed before (T0) and after 10 sessions of treatment (T1) and at a 12-week follow-up (T2). Pain, function and psychological measurements were conducted by means of different questionnaires. RESULTS: Both treatments improved all outcomes at post-treatment (T1) and follow-up (T2). The MIG showed a significant improvement in anxiety disorder associated with FM with respect to the CG, as well as improvements in coping strategies. CONCLUSIONS: Rehabilitation treatment based on motor imagery showed a stronger effect on anxiety and coping behavior than traditional physiotherapy in patients with FM. Integrated psychological support would be desirable in this setting. Further research is needed to explore the aspects investigated in more depth.

Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Stroke: One-Year Follow-up

2020 ◽  
Vol 34 (7) ◽  
pp. 609-615
Author(s):  
Jesse Dawson ◽  
Navzer D. Engineer ◽  
Cecília N. Prudente ◽  
David Pierce ◽  
Gerard Francisco ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Vagus Nerve ◽  
Upper Limb ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Exercise Program ◽  
Home Exercise ◽  
Home Exercise Program

Background. Vagus nerve stimulation (VNS) paired with rehabilitation may improve upper-limb impairment and function after ischemic stroke. Objective. To report 1-year safety, feasibility, adherence, and outcome data from a home exercise program paired with VNS using long-term follow-up data from a randomized double-blind study of rehabilitation therapy paired with Active VNS (n = 8) or Control VNS (n = 9). Methods. All people were implanted with a VNS device and underwent 6 weeks in clinic therapy with Control or Active VNS followed by home exercises through day 90. Thereafter, participants and investigators were unblinded. The Control VNS group then received 6 weeks in-clinic Active VNS (Cross-VNS group). All participants then performed an individualized home exercise program with self-administered Active VNS. Data from this phase are reported here. Outcome measures were Fugl-Meyer Assessment—Upper Extremity (FMA-UE), Wolf Motor Function Test (Functional and Time), Box and Block Test, Nine-Hole Peg Test, Stroke Impact Scale, and Motor Activity Log. Results. There were no VNS treatment–related serious adverse events during the long-term therapy. Two participants discontinued prior to receiving the full crossover VNS. On average, participants performed 200 ± 63 home therapy sessions, representing device use on 57.4% of home exercise days available for each participant. Pooled analysis revealed that 1 year after randomization, the FMA-UE score increased by 9.2 points (95% CI = 4.7 to 13.7; P = .001; n = 15). Other functional measures were also improved at 1 year. Conclusions. VNS combined with rehabilitation is feasible, with good long-term adherence, and may improve arm function after ischemic stroke.

Corrective osteotomy for malunited metacarpal fractures: long-term results of a novel technique

2015 ◽  
Vol 40 (8) ◽  
pp. 840-845 ◽  
Author(s):  
K. Karthik ◽  
R. Tahmassebi ◽  
R. S. Khakha ◽  
J. Compson
Keyword(s):  
Plate Fixation ◽  
Hand Function ◽  
Corrective Osteotomy ◽  
Long Term Results ◽  
Wedge Osteotomy ◽  
Dominant Hand ◽  
Level Of Evidence ◽  
Metacarpal Fractures

Symptomatic malunited metacarpal fractures can significantly affect hand function. We retrospectively reviewed the results of our technique of corrective osteotomy in 14 malunited metacarpal fractures (12 patients) with an average age of 30 years (range 18–49) from January 2005 to December 2011. The dominant hand was involved in nine patients and all except one were male. The malunited metacarpals demonstrated mean dorsal apex angulation of 43° (range 33°–72°) with apparent metacarpal shortening. All except three cases had rotational deformity. All patients underwent surgical correction of the deformity using our described technique of closing wedge osteotomy using temporary intramedullary K-wire and plate fixation. At a mean follow-up of 46 months (range 12–78), the DASH scores improved significantly ( p < 0.001). All our patients scored ‘excellent’ according to the Büchler criteria and at final follow-up had returned to pre-injury work and sports activities. Our technique is safe, easily performed and can be adapted to correct a range of deformities. Level of evidence: Level IV

scholarly journals Effects of strength, stretching and balance home exercise program on quality of life of people with knee osteoarthritis

2018 ◽  
Vol 8 (1) ◽  
pp. 35-41
Author(s):  
Amila Kapetanović ◽  
Adila Horić ◽  
Dijana Avdic ◽  
Amila Jaganjac ◽  
Emina Softić
Keyword(s):  
Quality Of Life ◽  
Knee Osteoarthritis ◽  
Exercise Program ◽  
Moderate Intensity ◽  
Home Exercise ◽  
Control Group ◽  
Study Group ◽  
Home Exercise Program ◽  
Average Value

Introduction: The aim of this study was to assess effects of strength, stretching and balance home exercise program (moderate intensity, performed once a day, five times a week) on quality of life of people with knee osteoarthritis. Methods: Participants with knee osteoarthritis performed physical therapy for a period of two weeks at the Department for Physical Medicine and Rehabilitation. The study group (n=30) continued to perform exercise program at home while the control group (n=30) did not continue the exercise program. The participants in the study group performed strength, stretching and balance exercises of moderate intensity, once a day, five times a week, for a total of eight weeks. The Short Form-36 Health Questionnaire (SF-36) was used to examine the effects of exercise program. Results: There was no the difference between the average value of quality of life in all examined areas (physical functioning, role limitations due to physical problems, role limitations due to emotional problems, vitality/energy, mental health, social functioning, physical pain, perception of general health) at the beginning of the study between the study group and control group (p>0.05 in all eight areas). The difference between the average value of quality of life at the beginning and end of the study was statistically significantly higher in the study group compared to the control group (physical functioning p=0.0001; role limitations due to physical problems p=0.0001; role limitations due to emotional problems p=0.0001; vitality/energy p=0.0001; mental health p=0.0001; social functioning p=0.0001; bodily pain p=0.0001; perception of general health p=0.0001). Conclusion: Home exercise program consisting of strength, stretching and balance exercises, of moderate intensity, performed once a day, five times a week is effective in improving quality of life of people with knee osteoarthritis.

Long-term results of the GEINO 1401 TRIAL: Randomizing patients to stop or to continue temozolomide until 12 cycles.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 2013-2013
Author(s):  
Marta Domenech ◽  
Carles Fabregat-Franco ◽  
Carlos Mesia ◽  
Anna Esteve ◽  
Sonia Del Barco Berron ◽  
...  
Keyword(s):  
Methylation Status ◽  
Progression Free Survival ◽  
Long Term Results ◽  
Control Group ◽  
Measurable Disease ◽  
Previously Treated ◽  
And Control ◽  
To Receive

2013 Background: We previously presented our results of the GEINO 1401 trial that randomized patients diagnosed with glioblastoma and treated with chemoradiotherapy and adjuvant temozolomide (TMZ) followed by six cycles of TMZ, to receive an extended use of TMZ up to 12 cycles or to control. We found no differences in 6-months neither progression free survival (PFS) nor overall survival (OS). In this report we actualize our results and analyse long-term survivor patients (LTSP). Methods: The trial NCT02209948 randomized (ratio 1:1) 159 patients diagnosed with glioblastoma who had been treated with standard therapy to stop treatment or to continue up to 12 cycles of TMZ. Patients were stratified based on their O6-methylguanine-DNA-methyltransferasa (MGMT) methylation status and presence or absence of measurable disease at inclusion. We update here OS outcomes and analyse the data of LTSP defined as an OS over 30 months from diagnosis. Results: At a median follow-up of 20 months, 82.4% of the patients had died and 89.9% had progressed. The median OS from randomization was 22.0 months for the control arm and 18.2 for the experimental arm: HR 0.957 (95%CI 0.806-1.136, p = 0.615). At 2 years from randomization there were a 61% of survivors in the TMZ group and 62% in the control group. There were a 49.7% of LTSP showing no differences between TMZ and control group. We found a higher prevalence of methylated MGMT in LTSP, but no differences were shown in patients with or without measurable disease at inclusion, status of IDH and the use of bevacizumab after progression. Conclusions: Adding 6 cycles of TMZ after the first 6 adjuvant cycles confers no additional benefit in OS. Nearly 50% of the patients included in GEINO 1401 who had been previously treated with TMZ 6 cycles without progressing were LTSP. Clinical trial information: NCT02209948.

The Management and Nature of Depressive Illnesses in Late Life: A Follow-Through Study

1972 ◽  
Vol 121 (563) ◽  
pp. 393-404 ◽  
Author(s):  
Felix Post
Keyword(s):  
Antidepressant Drugs ◽  
Late Life ◽  
Long Term Results ◽  
Control Group ◽  
Consecutive Series ◽  
Convulsive Therapy ◽  
After Care ◽  
Electro Convulsive Therapy

Since the long-term results of the treatment of elderly depressives admitted to the writer's care between 1949 and 1951 were communicated (1962), further experiences (e.g. Colwell and Post, 1959; Post, 1968) have confirmed that affective illnesses in late life are associated with much subsequent mental invalidism and needs for further treatment. It was hoped that these needs might be met by increased use of out-patient and community care as well as by the introduction of thymoleptic drugs. A follow-up investigation of a further consecutive series of depressives over the age of 60 receiving inpatient treatment from the same psychiatrist in the same hospital during the years 1966–67 was undertaken with the following aims in view:Firstly, it was intended to test the proposition that the less reluctant use of electro-convulsive therapy in old persons, as well as the introduction of antidepressant drugs and of more active after-care measures, had improved the long term outlook in the affective illnesses of late life. It was realized that a comparison of two series of patients separated from one another by some 15 years might be vitiated by differences between the samples other than those due to changed methods of treatment. It would, however, have been unethical to withhold the new forms of management from a control group.

scholarly journals Effect of an educational rehabilitation program on prevention of falls after stroke

2020 ◽  
Vol 10 (11) ◽  
pp. 31
Author(s):  
Esmat Sayed Abd-Almageed ◽  
Asmaa Sayed Abd-Almageed ◽  
Marwa Ali Almasry ◽  
Heba Mohamed Fahmy ◽  
Ghaydaa A. Shehata
Keyword(s):  
Rehabilitation Program ◽  
Medical Attention ◽  
Control Group ◽  
Study Group ◽  
Group Recommendation ◽  
Stroke Patients ◽  
Assessment Sheet ◽  
Quasi Experimental ◽  
And Control

Objective: Fall is common in patient with stroke. The aim of the study was to evaluate the effect of an educational rehabilitation program on prevention of falls after stroke.Methods: Quasi-experimental design was utilized. Setting: Neurology Department and Outpatient Clinics at Neurology, Psychiatry and Neurosurgery Hospital at Assiut University. Sample: Sixty adult patients diagnosed with stroke. Patients were equally divided into two equal groups (study and control) 30 patients each. Tools: Tool I-Patient assessment sheet. Tool II-Morse Fall Scale.Results: A statistically significant improvement of circumstances and consequences of falls and decreasing the injuries due to fall (p < .01) among the study group in comparison to the control group ones where, study group showed a decrease in the number of falling episodes (2.07 ± 0.78 vs. 5.4 ± 1.73), an improve in their ability to get up independent (83% vs. 23.3%), no need for medical attention (3.3% vs. 66.7%), and no restriction to their activities after falling (0.0% vs. 56.7%).Conclusions: The educational rehabilitation program had a statistically significant effect on the improvement of circumstances and consequences of falls and decreasing the injuries due to fall among the study group than among the control group. Recommendation: Simple illustrated educational booklets should be available for stroke patients. Replication of this study on a larger sample with extending the follow-up period to 6 months is suggested.

scholarly journals A Prospective 30-Year Follow-Up of ADHD Associated With Perinatal Risks

2014 ◽  
Vol 21 (10) ◽  
pp. 799-810 ◽  
Author(s):  
Timo Tervo ◽  
Katarina Michelsson ◽  
Jyrki Launes ◽  
Laura Hokkanen
Keyword(s):  
Control Group ◽  
Study Group ◽  
Adhd Symptoms ◽  
Learning Impairments ◽  
Adult Outcome ◽  
Psychiatric Problems ◽  
Motor Perception ◽  
Perinatal Risks

Objective: Longitudinal follow-up of ADHD suggests a poorer outcome in those affected. Studies extending to 30 years however are rare. We investigated the adult outcome of ADHD associated with perinatal risks (PRs), treated non-pharmacologically. Method: A study group of 122 participants (86 men, 36 women) with PR-associated ADHD was followed-up from birth and compared with a control group also prospectively studied. Results: The study group showed more cognitive, motor perception, and learning impairments as well as psychiatric problems at ages 5, 9, and 16. At age 30, the study group reported less education, more involuntary job dismissals and more alcohol abuse. Self-reported ADHD symptoms were still prevalent in adulthood. Conclusion: ADHD symptoms persist and impair the long-term educational, occupational, and psychiatric outcome. ADHD in participants with PR appears to follow a course seen in studies of unselected ADHD.

scholarly journals Long-term attitude towards follow-up colposcopy in women of reproductive age after excisional treatment for cervical dysplasia

2019 ◽  
Vol 147 (5-6) ◽  
pp. 321-326
Author(s):  
Radmila Sparic ◽  
Dimitrios Papoutsis ◽  
Svetlana Spremovic-Radjenovic ◽  
Sasa Kadija ◽  
Zoran Bukumiric ◽  
...  
Keyword(s):  
Condom Use ◽  
Cervical Dysplasia ◽  
Reproductive Age ◽  
Living Alone ◽  
Anxiety And Depression ◽  
Control Group ◽  
Study Group ◽  
Women Of Reproductive Age

Introduction/Objective. Very little is known about the factors influencing women?s attitude towards colposcopy follow-up after cervical treatment. The aim of the study was to investigate the long-term attitude to follow-up colposcopy in women of reproductive age after cervical excision and to evaluate if their attitude was related to their anxiety and depression levels. Methods. Women treated with cervical excision were interviewed after a follow-up colposcopy visit. Their socio-demographic and clinical characteristics were recorded. All women filled in the Beck?s anxiety and depression inventory. Results. A total of 160 women were divided into the study group of 42 (26.3%) women who felt discomfort during follow-up colposcopy and the control group of 118 (73.7%) women who did not report such feelings. The mean age of the total sample was 35.3 ? 5.4 years with median time after treatment being five years (range: 2?18). Women in the study group had a significantly lower BMI values, had higher rates of nulliparity and nulligravidity, were more often single or living alone, and had significantly changed their attitude towards condom use after treatment. Beck?s anxiety and depression scores were significantly higher in the study group. Multivariate analysis showed that independent predictors of discomfort during follow-up colposcopy were anxiety levels (OR: 1.06; 95% CI: 1?1.12), living alone or without a partner (OR: 2.65; 95% CI: 1.08?6.55), and the change in their practice of condom use after treatment (OR: 2.69; 95% CI: 1.02?7.07). Conclusion. Almost one third of women after excisional treatment reported discomfort during their follow-up colposcopy. These women exhibited higher levels of anxiety.

scholarly journals Prevention of embolism in patients with atrial fibrillation after resection of left atrium appendage during open heart surgery (pilot study)

2018 ◽  
Vol 10 (2) ◽  
pp. 52-57 ◽  
Author(s):  
A V Sotnikov ◽  
M V Melnikov ◽  
V A Marinin ◽  
Yu V Kisil ◽  
K V Samko
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrium ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Radical Resection ◽  
Long Term Results ◽  
Control Group ◽  
Study Group ◽  
Open Heart

Aim. To assess the potential of prevention cardiogenic embolism by resection of left atrium appendage (LAA) during open heart surgery in patients with atrial fibrillation (AFib). Materials and methods. Study design - cohort prospective. Study group consisted of 19 patients with AFib whom during open heart surgery for coronary and/or valvular disease additional radical resection of LAA was made. After removal of the appendage two-layer linear suture to left atrium was performed without leaving a stump. Control group consisted of 20 patients with AFib, in whom during open heart surgery LAA remained intact. Long-term results were studied using CROQ telephone questionnaire. Results. There was no hospital mortality in both groups. Long-term results in control group were followed up to 6 years, in study group up to 2 years. Radical resection of LAA in patients with AFib reduced the risk of thromboembolic events in long-term period. In control group there were 4 strokes (2 of them were fatal), but no strokes in study group (p < 0,05). Conclusion. Radical resection of LAA in patients with AFib during open heart surgery for coronary and/or valvular disease prevents cardiogenic arterial embolism. (For citation: Sotnikov AV, Melnikov MV, Marinin VA, et al. Prevention of embolism in patients with atrial fibrillation after resection of left atrium appendage during open heart surgery (pilot study). Herald of North-Western State Medical University named after I.I. Mechnikov. 2018;10(2):52-57. doi: 10.17816/mechnikov201810252-57).

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