scholarly journals The profile of microorganisms that associate with acute tonsillitis in children and their antibiotics sensitivity pattern in Nigeria

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maduka Donatus Ughasoro ◽  
James Onuorah Akpeh ◽  
Nneamaka Echendu ◽  
Nneka Gertrude Mgbachi ◽  
Somkene Okpala ◽  
...  
Keyword(s):  
Susceptibility Pattern ◽  
Childhood Diseases ◽  
Acute Tonsillitis ◽  
Cross Sectional ◽  
Antimicrobial Susceptibility Pattern ◽  
Presenting Symptoms ◽  
Sensitivity Pattern ◽  
Antibiotic Susceptibility Test ◽  
Antibiotics Sensitivity ◽  
High Level

AbstractAcute tonsillitis remains one of the common childhood diseases in developing countries. Prompt and appropriate treatment based on the knowledge of the causative microbiota and their antimicrobial susceptibility pattern will improve the treatment outcome and reduce time and resources spent on treatment. This study aims to determine the pattern of microbiota isolates and their susceptibility pattern. The study was a combination of the retrospective and cross-sectional method. The medical records of children treated for tonsillitis were retrieved, as well as those of children who presented with acute tonsillitis for the study. Interviewer-administered questionnaire was used to collect data, as well as document information retrieved from their medical record: presenting symptoms, treatments received. Swab sample was taken for culture and antibiotic susceptibility test. Out of the 72 swab cultures, 29 (40.3%) yielded insignificant growth of gram positive cocci. A total of nine (9) different isolates were obtained from all the significant swab cultures. Streptococcus species (13, 18.6%) and staphylococcus species (11, 15.3%) were the commonest isolates. Imipenem and levofloxacin revealed high level of susceptibility, while Ampicillin and Cefexine recorded high resistance rates. The proportion of the cultures that were positive of significant growth, the proportion of these positive isolates that were Streptococcus spp. and varied sensitivity pattern obtained underpinned the importance to advocate for culture isolates and susceptibility pattern guided treatment. These will not only an efficient approach to management of acute tonsillitis, but also a strong approach towards effective implementation of antibiotic stewardship.

Bacterial Microbiota and Antibiogram Profile in Children With Acute Tonsillitis. A Guide to Treatment.

2021 ◽  
Author(s):  
Maduka Ughasoro ◽  
James Akpeh ◽  
Nneamaka Echendu ◽  
Nneka Mgbachi ◽  
Somkene Okpala ◽  
...  
Keyword(s):  
Susceptibility Pattern ◽  
Childhood Diseases ◽  
Acute Tonsillitis ◽  
Cross Sectional ◽  
Antimicrobial Susceptibility Pattern ◽  
Presenting Symptoms ◽  
Sensitivity Pattern ◽  
Antibiotic Susceptibility Test ◽  
High Level ◽  
Resistance Rates

Abstract Purpose: Acute tonsillitis remains one of the common childhood diseases in developing countries. Prompt and appropriate treatment based on the knowledge of the causative microbiota and their antimicrobial susceptibility pattern will improve the treatment outcome and reduce time and resources spent on treatment. This study aimed to determine the pattern of microbiota isolates and their susceptibility pattern. Methods: The study was a combination of retrospective and cross-sectional method. The medical records of children treated for tonsillitis were retrieved, as well as children who presented with acute tonsillitis were recruited in the study. Interviewer-administered questionnaire was used to collect data, as well as document information retrieved from their medical record: presenting symptoms, treatments received. Swab sample was taken for culture and antibiotic susceptibility test. Results: Out of the 72 swab cultures, most 29 (40.3%) yielded insignificant growth of gram positive cocci. A total of nine (9) different isolates were obtained from all the significant swab culture. Streptococcus species (13, 18.6%) and staphylococcus species (11, 15.3%) were the commonest isolates. Imipenem and levofloxacin revealed high level of susceptibility, while Ampicillin and Cefixine recorded high resistance rates. Conclusion: The proportion of the cultures that were positive of significant growth, the proportion of these positive isolates that were Streptococcus Spp. and varied sensitivity pattern obtained underpinned the important to advocate for culture isolates and susceptibility pattern guided treatment. This will not only an efficient approach to management of acute tonsillitis, but also a strong approach towards effective implementation of antibiotic stewardship.

Bacteriology of wound infections and Antibiotic susceptibility pattern of the Isolates

2021 ◽  
pp. 81-85
Author(s):  
Venkateswaramurthy N ◽  
Ashli Raj V ◽  
Nisharani SS ◽  
Limna AL ◽  
Chandini S ◽  
...  
Keyword(s):  
Microbial Growth ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Wound Infections ◽  
Susceptibility Pattern ◽  
Antibiotic Susceptibility Pattern ◽  
Sensitivity Pattern ◽  
High Level ◽  
Culture Positive

Wound infection has always been a major complication of surgery and trauma. The aim of our study was to determine the bacteriology of wound infections and to study the antibiotic susceptibility pattern of the isolates. The study was conducted in tertiary care hospital, Erode. The design of the study was a prospective type. Pus swabs / specimens were collected from hospitalized patients who developed wound infections. Bacterial pathogens were identified by conventional biochemical methods according to standard microbiological techniques. Antimicrobial susceptibility was performed on Muller – Hinton agar by the standard disk diffusion method. The incidence of wound infection was more common in males (63%) than in females (37%). Out of 100 culture positive samples, 61 samples were collected from diabetic ulcer patients, 20 samples were from ulcer patients, and 19 samples were from post operative patients. Of the 100 samples (culture positive), 71% collected samples showed mono-microbial growth, 29% showed two type of microbial growth. The prevalence of S. aureus (62.87%) from different wound infections was found to be high, followed by E.coli (48.65%), Klebsiella (30.21%), Pseudomonas (22.16%). Organisms showed diversity in the sensitivity pattern towards the antibiotics tested. High level of sensitivity was observed to Imipenem, Piperacillin tazobactum and Amikacin. High level of resistance was observed to Cephalosporins and Penicillin derivatives. We concluded that the sensitivity pattern of the antibiotics is not based on the infection site but on the type of organisms. This study gives us an insight to the current state of causative pathogens and their sensitivity to different antibiotics used in tertiary care hospital, Erode. The data of this study may be used to determine trends in antimicrobial susceptibilities and to modify antibiotic policy of the Hospital.

scholarly journals EVALUATION OF ANTIBIOTIC SENSITIVITY PATTERN IN ACUTE TONSILLITIS

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Sadhana Joshi ◽  
Gaurav Parashar
Keyword(s):  
Prospective Observational Study ◽  
Antibiotic Sensitivity ◽  
High Sensitivity ◽  
Acute Tonsillitis ◽  
Sensitivity Pattern ◽  
History Of ◽  
Amoxicillin Clavulanic Acid ◽  
Antibiotics Sensitivity ◽  
Low Sensitivity ◽  
Body Ache

Background: Tonsillitis is a frequent condition noticed in the ENT department of every hospital. One out of every 10 children visiting the ENT OPD, suffer from acute tonsillitis. Methods: This was a prospective observational study conducted on patients coming with a history of throat pain, pain on swallowing, fever, body ache and other constitutional symptoms. Results: Antibiotic resistance was seen in case of the commonly used antibiotics like ampicillin, amoxicillin, Amoxicillin+Clavulanic acid. Cephalosporins were less commonly used antibiotics and showed resistance in 78.00% cases. Cotrimoxazole showed about 16.00% resistant cases. The less commonly used antibiotic was vancomycin however, showed high sensitivity (100%) followed by Linezolid (92.00%) and Clindamycin (82.00%). Erythromycin showed 76% sensitivity while ciprofloxacin showed a low sensitivity of 40.00% followed by Cephalosporins (22.0%). Conclusion: The antibiotic sensitivity pattern could revolutionize the management of chronic tonsillitis. Keywords: Acute tonsillitis, Antibiotics, Sensitivity

scholarly journals Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections, in a suburban tertiary care hospital in Mumbai

2021 ◽  
Vol 8 (10) ◽  
pp. 3046
Author(s):  
Sarang Degloorkar ◽  
B. C. Shah ◽  
Kinjal Patel
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Susceptibility ◽  
Diabetic Foot ◽  
Successful Outcome ◽  
Care Hospital ◽  
Common Complication ◽  
Susceptibility Pattern ◽  
Antimicrobial Susceptibility Pattern ◽  
Diabetic Foot Infections ◽  
Sensitivity Pattern

Background: The most common complication observed in patients with diabetes mellitus is diabetic foot infection; it is the bone or soft tissue infection below the malleoli. The most common pathogens involved in this infection are Staphylococcus species and beta haemolytic streptococci. Severe, chronic, or formerly dealt with infections are usually polymicrobial. Hence, the aim of the study was to understand the microbiological profile and antimicrobial susceptibility pattern of pathogens causing diabetic foot infections.Methods: Post approval from Institutional Ethics Committee, a retrospective study was carried out based on review of records of 117 patients with diabetic foot infections over two-year period from 2018 through 2019. All demographical and microbiological data was analysed.Results: Out of 117 patients of diabetic foot infections, 71 (60.68%), patients showed bacterial growth. Amongst 71 patients 45% of patients had gram positive infection. 52% patients had gram negative infection. 3% patients had poly-microbial growth. Most common organism isolated were Staphylococcus aureus 28%, Morgaellamorgagni 11%, Proteus mirabilis 9%, Citrobacter koseri 8%, E. coli 8%. Incidence of Staphylococcus aureus (MRSA and MSSA) was 3% each. Staphylococcus aureus had sensitivity to Rifampicin, Cefoperazone, Tigecycline.Conclusions: Diabetic foot infections are common complication worldwide. Understanding the microbiology will help to deal better in management and prognosis of patients. Hence, it is mandatory to characterize the causative agents, and its antimicrobial susceptibility pattern to ensure successful outcome of diabetic foot infections.

scholarly journals Antimicrobial Susceptibility Pattern of Bacterial Isolates from Patients with Chronic Suppurative Otitis Media

2020 ◽  
Vol 22 (2) ◽  
pp. 90-95
Author(s):  
Salah Uddin Ahmmed ◽  
AKM Asaduzzaman ◽  
Basir Ahmed ◽  
Monsur Alam ◽  
Misbah AL Kabir ◽  
...  
Keyword(s):  
Otitis Media ◽  
Antimicrobial Susceptibility ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
Bacterial Isolates ◽  
Suppurative Otitis Media ◽  
Antimicrobial Susceptibility Pattern ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
High Level

Background: Chronic suppurative otitis media (CSOM) is one of the common diseases of the middle ear especially in developing countries. Early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity pattern ensures prompt clinical recovery and possible complications may be avoided. Objectives: This study was done to determine the pattern of bacterial isolates and to detect their antibiogram. Methods: A total of 103 patients clinically diagnosed of CSOM were enrolled in the study and the samples were obtained from each patient using sterile cotton swabs and cultured for bacterial isolates. Antimicrobial susceptibility test of the isolates were performed using Kirby- Bauer disc diffusion method. Results: Among the cases females were more affected than males. Out of the 103 cases, bacteriological investigation revealed that Pseudomonas aeruginosa 42 (44.68%) and Staphylococcus aureus 31(32.97%) were the predominant bacteria. Ciprofloxacin and Ceftazidime revealed high level of sensitivity whereas high resistance rates were observed for Amoxycillin, Gentamicin and Cephalexin. Conclusion: The study concluded that an appropriate knowledge of the etiological agents and antibacterial susceptibility of microorganisms would contribute to a rational use of antibiotics, success of treatment and reduce the complications of CSOM. Bangladesh J Otorhinolaryngol; October 2016; 22(2): 90-95.

Study of bacterial infection and antimicrobial sensitivity pattern in diabetic foot lesion

2012 ◽  
Vol 6 (2) ◽  
pp. 20-23
Author(s):  
Shameem Akhter ◽  
Shah Md Zahurul Haque Asna ◽  
M Mushfequr Rahman ◽  
MA Hafez
Keyword(s):  
Diabetic Foot ◽  
Cross Sectional Study ◽  
Microbial Pathogens ◽  
Cross Sectional ◽  
Female Ratio ◽  
Antimicrobial Susceptibility Pattern ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Foot Lesions ◽  
Diabetic Foot Lesions

A cross sectional study was carried out on patients with diabetic foot lesions to determine the spectrum of aerobic microbial flora and to determine the microbial pathogens of the diabetic foot lesions and their antimicrobial sensitivity pattern. A total of 226 organisms were isolated from 218 patients and polymicrobial infection was found in 3.7 % cases. Age of the study population ranged from 20 - >80 yrs of which most of the patients were from 40 to 70 yrs (81 %). Male female ratio was= 3:1. In this study, Pseudomonas sp. (22.1 %), Proteus mirabilis (16.4 %) and S. aureus (14.6 %) were the predominant organisms isolated. Antimicrobial susceptibility pattern of the isolates were done in which imipenem and ciprofloxacin were found to be the most effective against all organisms.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19372 Bangladesh J Med Microbiol 2012; 06(02): 20-23

scholarly journals Antimicrobial sensitivity pattern of Salmonella typhi isolated from blood culture in a referral hospital

2011 ◽  
Vol 5 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Bulbul Hasan ◽  
Sabera Gul Nahar ◽  
Laila Akter ◽  
Ahmed Abu Saleh
Keyword(s):  
Blood Culture ◽  
Typhoid Fever ◽  
Antimicrobial Susceptibility ◽  
Salmonella Typhi ◽  
Susceptibility Pattern ◽  
Widal Test ◽  
College Hospital ◽  
Medical College ◽  
Antimicrobial Susceptibility Pattern ◽  
Sensitivity Pattern

The present study has been carried out in an attempt to evaluate antimicrobial susceptibility patterns with special reference to susceptibility of Salmonella Typhi to ciprofloxacin isolated from blood culture. The study is also designed to find out the MIC of Ciprofloxacin by E- test. Blood samples were taken for culture sensitivity, Widal test and ICT from 100 clinically suspected cases of typhoid fever in 1st week of illness who attended at out patient department of Rajshahi Medical College Hospital (RMCH).The study was done in Microbiology Department of Rajshahi Medical College and Shishu Hospital, Dhaka. Diagnosis of patients was based on history of fever, blood culture, Widal test and ICT. The antimicrobial susceptibility pattern of isolates from blood culture was recorded. Further more, the minimum inhibitory concentration of Ciprofloxacin was determined by E-test for the isolates resistance to Ciprofloxacin. Out of 100 suspected cases of typhoid fever, blood culture positive for S. Typhi were 16 (16%). Antimicrobial susceptibility pattern of 16 isolates of S. Typhi showed that no isolate was resistant to Ceftriaxone and Ceftazidime, only 03(18.75%) were resistant to Ciprofloxacin and Azithromycin whereas 10(62.5%) were MDR showing resistance to Ampicillin, Co-trimoxazole and Chloramphenicol which are first-line antityphoidal drugs. On the other hand, all (100%) the isolates were resistant to Nalidixic acid. The study revealed that Ceftriaxone and Ceftazidime are the most effective drugs in the treatment of typhoid fever. Moreover, E-test has been found to be helpful to determine appropriate therapeutic dose of Ciprofloxacin especially in case of drug resistance and pediatric population.DOI: http://dx.doi.org/10.3329/bjmm.v5i1.15816 Bangladesh J Med Microbiol 2011; 05 (01): 16-20

Sign in / Sign up

Export Citation Format

Share Document