Syntheses, structures and antimicrobial activities of water-soluble silver(i)–oxygen bonding complexes with chiral and racemic camphanic acid (Hca) ligands

2004 ◽  
pp. 3732-3740 ◽  
Author(s):  
Noriko Chikaraishi Kasuga ◽  
Akiyoshi Sugie ◽  
Kenji Nomiya
Keyword(s):  
Antimicrobial Activities ◽  
Water Soluble ◽  
Camphanic Acid

scholarly journals Novel Prosopis juliflora leaf ethanolic extract as natural antimicrobial agent against food spoiling microorganisms

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Iman Saleh ◽  
Mohammed H. Abu-Dieyeh
Keyword(s):  
Mycelial Growth ◽  
Ethanolic Extract ◽  
Geotrichum Candidum ◽  
Antimicrobial Activities ◽  
Prosopis Juliflora ◽  
Water Soluble ◽  
Small Scale ◽  
Health And Environmental Effects ◽  
Total Inhibition ◽  
Global Increase

AbstractFresh produces spoilage is a worldwide concern that accompany the global increase in food demand. Adverse human health and environmental effects of commercial spoilage control agents are major public concern. In this study, Prosopis juliflora leaves and fruit extracts had their antimicrobial activities evaluated against the growth of selected bacteria and yeast, and against mycelial growth and conidial germination of selected mycotoxins-producing fungi. P. juliflora water-soluble leaf ethanolic (PJ-WS-LE) extract with its novel extraction method showed the strongest antibacterial activity. Antimicrobial tests showed total inhibition of Botrytis cinerea, Alternaria alternata, Bacillus subtilis, Staphylococcus aureus and Candida albicans with MICs ranging between 0.125 and 1 mg/ml. Percent inhibition of mycelial growth (PIMG) of the extract was also determined against seven other fungal strains with highest value against Geotrichum candidum (66.2%). Even the least affected fungal strain showed alterations in their hyphae and spores exposed to PJ-WS-LE extract when observed using scanning electron microscope (SEM), alterations include exfoliated flakes, pores, vacuolation and applanation. Small-scale fruit bioassays controlled experiment showed high efficacy of the extract in protecting inoculated cherry tomato samples from B. cinerea and A. alternata infections. In conclusion, PJ-WS-LE extract is a feasible, natural antifungal agent that can replace common anti-spoiling chemicals.

scholarly journals Antioxidant and antibacterial insights into the leaves, leaf tea and medicinal roots from Astragalus membranaceus (Fisch.) Bge.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Anim Okyere Samuel ◽  
Bao-Ting Huang ◽  
Yuan Chen ◽  
Feng-Xia Guo ◽  
Dou-Dou Yang ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Activities ◽  
Antimicrobial Activities ◽  
Water Soluble ◽  
Astragalus Membranaceus ◽  
Total Amino Acid ◽  
Total Phenolic ◽  
Plant Leaves ◽  
Bioactive Components ◽  
Wide Range

AbstractUsed as traditional Chinese medicine, Astragalus membranaceus (Fisch.) Bge. (A. membranaceus) roots are also used as tonic food material in a wide range of applications, while the leaves are left in the field, unused. Therefore, comprehensively exploring and utilizing the leaves will inevitably reduce the associated resource waste and environment pollution. In this study, the plant leaves were processed into tea using green tea processing technology. Bioactive components, antioxidant and antibacterial activities of the Leaf Tea (LT) and Dry Leaves (DL) were studied, and compared to that of the Dry Roots (DR). The results showed that the polysaccharides content (POL) in the DR (20.44%) was twice as high as the DL (10.18%) and LT (8.68%). However, the DL contained 36.85% more water-soluble extracts (WSE), 35.09% more ethanol-soluble extracts (ESE), 409.63% more total flavonoid content (TFC), 221.01% more total phenolic content (TPC) and 94.34% more proteins, and the LT contained 26.21% more WSE, 40.64% more ESE, 326.93% more TFC, 191.90% more TPC and 37.71% more proteins. The total amino acid (AA) content in the DR was 8.89%, while in that of the DL and LT were 24.18% and 28.96% respectively, nearly 3-times higher than that of the DR. The antioxidant activity of DR was much lower than those of DL and LT, both of which had antioxidant activity closer to that of Vitamin C (VC) and the antioxidant activities were even stronger when the optimal concentration was reached. Except for Aspergillus niger and Staphylococcus aureus, the DL and DR exhibited inhibition activities to Salmonella, Bacillus subtilis, Escherichia coli and yeast, while the LT had antimicrobial activities against all the strains except for A. niger. In summary, compared with the most commonly used DR, the DL and LT from A. membranaceus contained higher bioactive components, and stronger antioxidant and antimicrobial activities. Producing leaf tea may be an appropriate way to economically and reasonably utilize the plant leaves which are by-products.

scholarly journals Active antibacterial coating of cotton fabrics with antimicrobial proteins

Cellulose ◽  
2021 ◽  
Author(s):  
Amy Y. Xu ◽  
Duncan J. McGillivray ◽  
Andrew J. Dingley
Keyword(s):  
Citric Acid ◽  
Surface Composition ◽  
Bacterial Species ◽  
Antimicrobial Activities ◽  
Cotton Fabrics ◽  
Attenuated Total Reflection ◽  
Water Soluble ◽  
Composition Analysis ◽  
Bacterial Strains ◽  
Antimicrobial Proteins

AbstractThe prevention of bacteria colonization by immobilizing proteins with antimicrobial activity onto cotton fabrics was investigated. Such coatings have potential applications in medical dressing materials used in wound care and healing. Two antimicrobial proteins lysozyme and hydramacin-1 (HM-1) were surface immobilized through two linkers (3-aminopropyl) triethoxysilane (APTES) and citric acid in the presence of the water soluble carbodiimide coupling reagent 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate. Surface composition analysis by attenuated total reflection-Fourier transform infrared and X-ray photoelectron spectroscopies confirmed formation of the protein-cellulose conjugates. Antimicrobial activities of the different functionalized surfaces were found to vary between APTES and citric acid directed coatings. Citric acid immobilized lysozyme treated samples demonstrated superior activity against Gram-positive Bacillus subtilis, whereas APTES immobilized HM-1 treated samples demonstrated an advantage in inhibiting the growth of Gram-negative Escherichia coli. The antibacterial activity and stability of citric acid immobilized protein fabrics following sonication, boiling and chemical treatment were noticeably higher than that of the corresponding APTES immobilized protein fabrics. The dual coating of fibers with both antimicrobial proteins afforded efficient antimicrobial activities against both bacterial species. The results suggest that coating cotton fibers with antimicrobial proteins and peptides represents a feasible approach for developing active surfaces that prohibit growth and colonization of bacterial strains and can be potentially used in medical cotton-based fabrics.

scholarly journals Synthesis, Antibacterial Evaluation and in Silico Study of DOTA-fluoroquinolone Derivativessynthesis, Antibacterial Evaluation and in Silico Study of DOTA-fluoroquinolone Derivatives

2021 ◽  
Author(s):  
Weitian Li ◽  
Ge Hong ◽  
Lina Mao ◽  
Zengping Xu ◽  
Jiawen Wang ◽  
...  
Keyword(s):  
In Silico ◽  
Antimicrobial Activities ◽  
Water Soluble ◽  
Stable Complex ◽  
Molecular Docking Study ◽  
Topoisomerase Iv ◽  
Water Soluble Compound ◽  
In Silico Study ◽  
Low Toxicity ◽  
Antibacterial Evaluation

Abstract A series of water-soluble fluoroquinolones based upon DOTA modification were synthesized and characterized by NMR and HRMS spectra. All the newly prepared quinolones compounds exhibited potent antimicrobial activities against MRSA, P. aeruginosa and E. coli. Molecular docking study indicated they could form stable complex with DNA gyrase and topoisomerase IV-DNA respectively, ADMET prediction showed they were low toxicity to the mice as whole. Among them, water-soluble quinolone 4c exhibited promising antibacterial potency, its MIC, MBC value for MRSA and P. aeruginosa was (1.56, 6.25) µg/mL, (3.1, 12.5) µg/mL respectively. Atomic Force Microscope (AFM) imaging revealed 4c could effectively destroy MRSA bacterial membrane and wall, causing its contents to leak out. Cytotoxicity assay showed 4c had low toxicity to L-02, A549 and MCF-7, over 80% cell viability even at 100 µmol/L. These results showed that water-soluble compound 4c was a promising antibacterial candidate.

Preparation of quaternary ammonium salt of chitosan nanoparticles and their textile properties on Antheraea pernyi silk modification

2014 ◽  
Vol 84 (19) ◽  
pp. 2115-2124 ◽  
Author(s):  
Yanhua Lu ◽  
Dehong Cheng ◽  
Sheng Lu ◽  
Fengyuan Huang ◽  
Gang Li
Keyword(s):  
Ammonium Salt ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salt ◽  
Chitosan Nanoparticles ◽  
Antimicrobial Activities ◽  
Water Soluble ◽  
Sodium Hypophosphite ◽  
Silk Fabric ◽  
Antheraea Pernyi ◽  
Initial Modulus

A novel eco-friendly finishing agent of quaternary chitosan nanoparticles was prepared in two steps from a chitosan with low molecular weight. The water-soluble quaternary ammonium salt of chitosan, N-[(2-hydroxy-3-trimethylammonium)propyl] chitosan chloride (HTCC), was first synthesized in heterogeneous system by quaternization, and then HTCC was further prepared to nanoparticles via ionotropic gelation reaction in the presence of 1, 2, 3, 4-butane tetracarboxylic acid and sodium hypophosphite. The size distribution and morphology of the HTCC particles were characterized using a laser particle size analyzer and transmission electron microscope (TEM). When Antheraea pernyi ( A. pernyi) silk fabric was treated with HTCC nanoparticles by using a conventional dip-pad-dry-cure process, the modified A. pernyi silk fabric demonstrated durable wrinkle-resistant property, shrinkage-resistant property and antimicrobial activities against Staphylococcus aureus and Escherichia coli, even after being exposed to 50 consecutive home-laundering conditions. However, the modification of A. pernyi silk fabric caused breaking strength loss, breaking elongation reduction and initial modulus rise to some extent.

Sign in / Sign up

Export Citation Format

Share Document