A kinetic and theoretical study of the borate catalysed reactions of hydrogen peroxide: the role of dioxaborirane as the catalytic intermediate for a wide range of substrates

Hormesis, which describes the stimulatory effect of low doses of toxic substances on growth, is a well-known phenomenon in the plant and animal kingdoms. However, the mechanisms that are involved in this phenomenon are still poorly understood. We performed preliminary studies on corn coleoptile sections, which showed a positive correlation between the stimulation of growth by Cd or Pb and an increase in the auxin and H2O2 content in the coleoptile sections. Subsequently, we grew corn seedlings in hydroponic culture and tested a wide range of Cd or Pb concentrations in order to determine hormetic growth stimulation. In these seedlings the gas exchange and the chlorophyll a fluorescence, as well as the content of chlorophyll, flavonol, auxin and hydrogen peroxide, were measured. We found that during the hormetic stimulation of growth, the response of the photosynthetic apparatus to Cd and Pb differed significantly. While the application of Cd mostly caused a decrease in various photosynthetic parameters, the application of Pb stimulated some of them. Nevertheless, we discovered that the common features of the hormetic stimulation of shoot growth by heavy metals are an increase in the auxin and flavonol content and the maintenance of hydrogen peroxide at the same level as the control plants.

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Exploring the Role of Phenylalanine Residues in Modulating the Flexibility and Topography of the Active Site in the Peroxygenase Variant PaDa-I

International Journal of Molecular Sciences ◽

10.3390/ijms21165734 ◽

2020 ◽

Vol 21 (16) ◽

pp. 5734

Author(s):

Joaquin Ramirez-Ramirez ◽

Javier Martin-Diaz ◽

Nina Pastor ◽

Miguel Alcalde ◽

Marcela Ayala

Keyword(s):

Hydrogen Peroxide ◽

Cytochrome P450 ◽

Active Site ◽

Bulk Solution ◽

Computational Studies ◽

Organic Substrates ◽

Oxidation Reactions ◽

Heme Group ◽

Wide Range

Unspecific peroxygenases (UPOs) are fungal heme-thiolate enzymes able to catalyze a wide range of oxidation reactions, such as peroxidase-like, catalase-like, haloperoxidase-like, and, most interestingly, cytochrome P450-like. One of the most outstanding properties of these enzymes is the ability to catalyze the oxidation a wide range of organic substrates (both aromatic and aliphatic) through cytochrome P450-like reactions (the so-called peroxygenase activity), which involves the insertion of an oxygen atom from hydrogen peroxide. To catalyze this reaction, the substrate must access a channel connecting the bulk solution to the heme group. The composition, shape, and flexibility of this channel surely modulate the catalytic ability of the enzymes in this family. In order to gain an understanding of the role of the residues comprising the channel, mutants derived from PaDa-I, a laboratory-evolved UPO variant from Agrocybe aegerita, were obtained. The two phenylalanine residues at the surface of the channel, which regulate the traffic towards the heme active site, were mutated by less bulky residues (alanine and leucine). The mutants were experimentally characterized, and computational studies (i.e., molecular dynamics (MD)) were performed. The results suggest that these residues are necessary to reduce the flexibility of the region and maintain the topography of the channel.

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The Problem of Identifying and Modeling the Relationship between Monetary Factor and Inflation in the Russian Economy

Voprosy Ekonomiki ◽

10.32609/0042-8736-2008-7-61-76 ◽

2008 ◽

pp. 61-76

Author(s):

A. Porshakov ◽

A. Ponomarenko

Keyword(s):

Money Supply ◽

Money Demand ◽

Russian Economy ◽

Long Run ◽

Complex Approach ◽

Wide Range ◽

Long Time ◽

The Relationship ◽

Supply Side Factors

The role of monetary factor in generating inflationary processes in Russia has stimulated various debates in social and scientific circles for a relatively long time. The authors show that identification of the specificity of relationship between money and inflation requires a complex approach based on statistical modeling and involving a wide range of indicators relevant for the price changes in the economy. As a result a model of inflation for Russia implying the decomposition of inflation dynamics into demand-side and supply-side factors is suggested. The main conclusion drawn is that during the recent years the volume of inflationary pressures in the Russian economy has been determined by the deviation of money supply from money demand, rather than by money supply alone. At the same time, monetary factor has a long-run spread over time impact on inflation.

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The role of copper ions in hydrogen peroxide bleaching: Their origin, removal, and effect on pulp quality

TAPPI Journal ◽

10.32964/tj11.7.37 ◽

2012 ◽

Vol 11 (7) ◽

pp. 37-46 ◽

Cited By ~ 1

Author(s):

PEDRO E.G. LOUREIRO ◽

SANDRINE DUARTE ◽

DMITRY V. EVTUGUIN ◽

M. GRAÇA V.S. CARVALHO

Keyword(s):

Hydrogen Peroxide ◽

Copper Ions ◽

Peroxide Bleaching ◽

Metals Removal ◽

Peroxide Decomposition ◽

Equipment Corrosion ◽

And Performance ◽

And Control ◽

Main Effects

This study puts particular emphasis on the role of copper ions in the performance of hydrogen peroxide bleaching (P-stage). Owing to their variable levels across the bleaching line due to washing filtrates, bleaching reagents, and equipment corrosion, these ions can play a major role in hydrogen peroxide decomposition and be detrimental to polysaccharide integrity. In this study, a Cu-contaminated D0(EOP)D1 prebleached pulp was subjected to an acidic washing (A-stage) or chelation (Q-stage) before the alkaline P-stage. The objective was to understand the isolated and combined role of copper ions in peroxide bleaching performance. By applying an experimental design, it was possible to identify the main effects of the pretreatment variables on the extent of metals removal and performance of the P-stage. The acid treatment was unsuccessful in terms of complete copper removal, magnesium preservation, and control of hydrogen peroxide consumption in the following P-stage. Increasing reaction temperature and time of the acidic A-stage improved the brightness stability of the D0(EOP)D1AP bleached pulp. The optimum conditions for chelation pretreatment to maximize the brightness gains obtained in the subsequent P-stage with the lowest peroxide consumption were 0.4% diethylenetriaminepentaacetic acid (DTPA), 80ºC, and 4.5 pH.

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Introduction: Emotion, History and the Arts

Cultural History ◽

10.3366/cult.2018.0169 ◽

2018 ◽

Vol 7 (2) ◽

pp. 117-128 ◽

Cited By ~ 1

Author(s):

Erin Sullivan ◽

Marie Louise Herzfeld-Schild

Keyword(s):

Historical Change ◽

Carson Mccullers ◽

Emotional Life ◽

Review Section ◽

The Arts ◽

Wide Range ◽

War Correspondents ◽

History Of ◽

Johan Huizinga

This introduction surveys the rise of the history of emotions as a field and the role of the arts in such developments. Reflecting on the foundational role of the arts in the early emotion-oriented histories of Johan Huizinga and Jacob Burkhardt, as well as the concerns about methodological impressionism that have sometimes arisen in response to such studies, the introduction considers how intensive engagements with the arts can open up new insights into past emotions while still being historically and theoretically rigorous. Drawing on a wide range of emotionally charged art works from different times and places—including the novels of Carson McCullers and Harriet Beecher-Stowe, the private poetry of neo-Confucian Chinese civil servants, the photojournalism of twentieth-century war correspondents, and music from Igor Stravinsky to the Beatles—the introduction proposes five ways in which art in all its forms contributes to emotional life and consequently to emotional histories: first, by incubating deep emotional experiences that contribute to formations of identity; second, by acting as a place for the expression of private or deviant emotions; third, by functioning as a barometer of wider cultural and attitudinal change; fourth, by serving as an engine of momentous historical change; and fifth, by working as a tool for emotional connection across communities, both within specific time periods but also across them. The introduction finishes by outlining how the special issue's five articles and review section address each of these categories, while also illustrating new methodological possibilities for the field.

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Short Films from a Small Nation

10.3366/edinburgh/9781474424134.001.0001 ◽

2018 ◽

Cited By ~ 1

Author(s):

C. Claire Thomson

Keyword(s):

Public Information ◽

Industrial Process ◽

Actor Network Theory ◽

Documentary Films ◽

Wide Range ◽

Short Films ◽

Post War ◽

The 1960S ◽

Art And Architecture

The first book-length study in English of a national corpus of state-sponsored informational film, this book traces how Danish shorts on topics including social welfare, industry, art and architecture were commissioned, funded, produced and reviewed from the inter-war period to the 1960s. For three decades, state-sponsored short filmmaking educated Danish citizens, promoted Denmark to the world, and shaped the careers of renowned directors like Carl Th. Dreyer. Examining the life cycle of a representative selection of films, and discussing their preservation and mediation in the digital age, this book presents a detailed case study of how informational cinema is shaped by, and indeed shapes, its cultural, political and technological contexts.The book combines close textual analysis of a broad range of films with detailed accounts of their commissioning, production, distribution and reception in Denmark and abroad, drawing on Actor-Network Theory to emphasise the role of a wide range of entities in these processes. It considers a broad range of genres and sub-genres, including industrial process films, public information films, art films, the city symphony, the essay film, and many more. It also maps international networks of informational and documentary films in the post-war period, and explores the role of informational film in Danish cultural and political history.

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Quantitative and Qualitative Methods of Studying the Processes of Socialization of a Modern Teenager

Siberian Pedagogical Journal ◽

10.15293/1813-4718.2006.10 ◽

2020 ◽

pp. 102-109

Author(s):

Svetlana Alekseevna Raschetina ◽

Keyword(s):

Research Methods ◽

Interpersonal Relations ◽

Internet Communication ◽

Socialization Process ◽

Wide Range ◽

The Family ◽

Modern Family ◽

Making Friends ◽

Main Support

Relevance and problem statement. Modern unstable society is characterized by narrowing the boundaries of controlled socialization and expanding the boundaries of spontaneous socialization of a teenager based on his immersion in the question arises about the importance of the family in the process of socialization of a teenager in the conditions of expanding the space of socialization. There is a need to study the role of the family in this process, to search, develop and test research methods that allow us to reveal the phenomenon of socialization from the side of its value characteristics. The purpose and methodology of the study: to identify the possibilities of a systematic and anthropological methodology for studying the role of the family in the process of socialization of adolescents in modern conditions, testing research methods: photo research on the topic “Ego – I” (author of the German sociologist H. Abels), profile update reflexive processes (by S. A. Raschetina). Materials and results of the study. The study showed that for all the problems that exist in the family of the perestroika era and in the modern family, it acts for a teenager as a value and the first (main) support in the processes of socialization. The positions well known in psychology about the importance of interpersonal relations in adolescence for the formation of attitudes towards oneself as the basis of socialization are confirmed. Today, the frontiers of making friends have expanded enormously on the basis of Internet communication. The types of activities of interest to a teenager (traditional and new ones related to digitalization) are the third pillar of socialization. Conclusion. The “Ego – I” method of photo research has a wide range of possibilities for quantitative and qualitative analysis of the socialization process to identify the value Pillars of this process.

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Victorian Culture and Classical Antiquity

10.23943/princeton/9780691149844.001.0001 ◽

2011 ◽

Cited By ~ 5

Author(s):

Simon Goldhill

Keyword(s):

Nineteenth Century ◽

Roman Empire ◽

Classical Antiquity ◽

Victorian Culture ◽

Wide Range ◽

Victorian Art ◽

Victorian Science ◽

Role Of Religion ◽

Nineteenth Century Novels

How did the Victorians engage with the ancient world? This book is an exploration of how ancient Greece and Rome influenced Victorian culture. Through Victorian art, opera, and novels, the book examines how sexuality and desire, the politics of culture, and the role of religion in society were considered and debated through the Victorian obsession with antiquity. Looking at Victorian art, it demonstrates how desire and sexuality, particularly anxieties about male desire, were represented and communicated through classical imagery. Probing into operas of the period, the book addresses ideas of citizenship, nationalism, and cultural politics. And through fiction—specifically nineteenth-century novels about the Roman Empire—it discusses religion and the fierce battles over the church as Christianity began to lose dominance over the progressive stance of Victorian science and investigation. Rediscovering some great forgotten works and reframing some more familiar ones, the book offers extraordinary insights into how the Victorian sense of antiquity and our sense of the Victorians came into being. With a wide range of examples and stories, it demonstrates how interest in the classical past shaped nineteenth-century self-expression, giving antiquity a unique place in Victorian culture.

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Role of Cardiac MRI in Detecting Familial Hypertrophic Cardiomyopathy: Review

Journal of Clinical and Health Sciences ◽

10.24191/jchs.v1i1.5846 ◽

2016 ◽

Vol 1 (1) ◽

pp. 4

Author(s):

Marymol Koshy ◽

Bushra Johari ◽

Mohd Farhan Hamdan ◽

Mohammad Hanafiah

Keyword(s):

Hypertrophic Cardiomyopathy ◽

Magnetic Resonance ◽

Genetic Disorder ◽

Familial Hypertrophic Cardiomyopathy ◽

Non Invasive ◽

Wide Range ◽

Proper Diagnosis ◽

Magnetic Resonance Imaging Mri ◽

Potential Use

Hypertrophic cardiomyopathy (HCM) is a global disease affecting people of various ethnic origins and both genders. HCM is a genetic disorder with a wide range of symptoms, including the catastrophic presentation of sudden cardiac death. Proper diagnosis and treatment of this disorder can relieve symptoms and prolong life. Non-invasive imaging is essential in diagnosing HCM. We present a review to deliberate the potential use of cardiac magnetic resonance (CMR) imaging in HCM assessment and also identify the risk factors entailed with risk stratification of HCM based on Magnetic Resonance Imaging (MRI).

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Synthetic and Mechanistic Studies of a Versatile Heteroaryl Thioether Directing Group for Pd(II) Catalysis

10.26434/chemrxiv.7927166.v1 ◽

2019 ◽

Author(s):

Andrew Romine ◽

Kin Yang ◽

Malkanthi Karunananda ◽

Jason Chen ◽

Keary Engle

Keyword(s):

Mechanistic Studies ◽

Salvianolic Acid ◽

Wide Range ◽

Computational Data ◽

Synthetic Utility ◽

Directing Group ◽

High Yields ◽

Julia Olefination ◽

Reaction Progress Kinetic Analysis

A weakly coordinating monodentate heteroaryl thioether directing group has been developed for use in Pd(II) catalysis to orchestrate key elementary steps in the catalytic cycle that require conformational flexibility in a manner that is difficult to accomplish with traditional strongly coordinating directing groups. This benzothiazole thioether, (BT)S, directing group can be used to promote oxidative Heck reactivity of internal alkenes providing a wide range of products in moderate to high yields. To demonstrate the broad applicability of this directing group, arene C–H olefination was also successfully developed. Reaction progress kinetic analysis provides insights into the role of the directing group in each reaction, which is supplemented with computational data for the oxidative Heck reaction. Furthermore, this (BT)S directing group can be transformed into a number of synthetically useful functional groups, including a sulfone for Julia olefination, allowing it to serve as a “masked olefin” directing group in synthetic planning. In order to demonstrate this synthetic utility, natural products (+)-salvianolic acid A and salvianolic acid F are formally synthesized using the (BT)S directed C–H olefination as the key step.

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