Trifluoroacetylazobenzene for optical and electrochemical detection of amines

2015 ◽  
Vol 3 (8) ◽  
pp. 4687-4694 ◽  
Author(s):  
Jhih-Fong Lin ◽  
Jarmo Kukkola ◽  
Teemu Sipola ◽  
Dilip Raut ◽  
Ajaikumar Samikannu ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Electrochemical Sensors ◽  
Practical Applications

Optical and electrochemical sensors based on 4-(dioctylamino)-4′-(trifluoroacetyl)azobenzene and its Nafion®–SWCNT composites show potential for practical applications in detecting various kinds of amines.

scholarly journals Multiplexed Detection of Sepsis Markers in Whole Blood using Nanocomposite Coated Electrochemical Sensors

2020 ◽  
Author(s):  
Uroš Zupančič ◽  
Pawan Jolly ◽  
Pedro Estrela ◽  
Despina Moschou ◽  
Donald E. Ingber
Keyword(s):  
Electrochemical Detection ◽  
Whole Blood ◽  
Electrochemical Sensors ◽  
Point Of Care ◽  
Sample Volume ◽  
Nanocomposite Coating ◽  
Cross Reactivity ◽  
Detection Methods ◽  
Clinical Samples ◽  
Undiluted Serum

ABSTRACTSepsis is a leading cause of mortality worldwide that is difficult to diagnose and manage because this requires simultaneous analysis of multiple biomarkers. Electrochemical detection methods could potentially provide a way to accurately quantify multiple sepsis biomarkers in a multiplexed manner as they have very low limits of detection and require minimal sensor instrumentation; however, affinity-based electrochemical sensors are usually hampered by biological fouling. Here we describe development of an electrochemical detection platform that enables detection of multiple sepsis biomarkers simultaneously by incorporating a recently developed nanocomposite coating composed of crosslinked bovine serum albumin containing a network of reduced graphene oxide nanoparticles that prevents biofouling. Using nanocomposite coated planar gold electrodes, we constructed a procalcitonin sensor and demonstrated sensitive PCT detection in undiluted serum and clinical samples, as well as excellent correlation with a conventional ELISA (adjusted r2 = 0.95). Sensors for two additional sepsis biomarkers — C-reactive protein and pathogen-associated molecular patterns — were developed on the same multiplexed platform and tested in whole blood. Due to the excellent antifouling properties of the nanocomposite coating, all three sensors exhibited specific responses within the clinically significant range without any cross-reactivity in the same channel with low sample volume. This platform enables sensitive simultaneous electrochemical detection of multiple analytes in human whole blood, which can be expanded further to any target analyte with an appropriate antibody pair or capturing probe, and thus, may offer a potentially valuable tool for development of clinical point-of-care diagnostics.GRAPHICAL ABSTRACT

scholarly journals Fabrication of Au Nanoparticle-Decorated MoS2 Nanoslices as Efficient Electrocatalysts for Electrochemical Detection of Dopamine

Catalysts ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 653 ◽  
Author(s):  
Chen ◽  
Chen ◽  
Hong
Keyword(s):  
Electrochemical Sensor ◽  
High Efficiency ◽  
Electrochemical Sensors ◽  
Au Nanoparticle ◽  
Dimensional Structure ◽  
Modified Carbon Paste Electrode ◽  
High Catalytic Activity ◽  
Carbon Paste ◽  
Practical Applications ◽  
Electrocatalytic Effect

Herein, MoS2 nanoslices were simply prepared by using ultrasonic treatment, and were further decorated with Au nanoparticles (AuNPs) through an electrodeposition process to obtain the MoS2/Au nanocomposites. The obtained nanocomposites display synergetic electrocatalytic effect for the oxidation of dopamine due to the large surface area and two-dimensional structure of the MoS2 nanoslices, combining with the high catalytic activity and good conductivity of AuNPs. An electrochemical sensor was constructed based on MoS2/Au-modified carbon paste electrode, for sensitive and quantitative determination of dopamine. The prepared electrochemical sensor proves excellent analytical performances: very high sensitivity, wide linear ranges (0.5–300 μM), and low detection limit (76 nM). Moreover, the dopamine sensor also displays high selectivity, good reproducibility and stability, and can be used in real sample analysis. The method of fabricating high-efficiency electrocatalysts and electrochemical sensors proposed in this study provides a good reference for developing more functionalized nanocomposites and for extending practical applications.

scholarly journals Agricultural product-derived carbon for energy, sensing, and environmental applications: A mini-review

2020 ◽  
Vol 27 (2) ◽  
pp. 467-478
Author(s):  
Syed Shaheen Shah ◽  
Md Abdul Aziz
Keyword(s):  
Water Splitting ◽  
Gas Separation ◽  
Electrochemical Sensors ◽  
Agricultural Product ◽  
Synthesis Methods ◽  
Chemical Compositions ◽  
Carbonaceous Materials ◽  
Human Welfare ◽  
Practical Applications ◽  
Wide Range

Carbon is one of the versatile materials used in modern life for human welfare. It has a wide range of applications such as drug delivery, coatings, energy generation and storage, gas separation, water purification, sensor fabrication, and catalysis. Most of the widely used carbon materials are graphene and carbon nanotubes. Nonrenewable precursors (e.g., natural gas), toxic chemicals, and complex synthesis methods are often required for their preparation, limiting their wide practical applications. Besides these, biomass-derived carbons are attractive materials as they can be prepared simply from renewable biomass. However, their practical applications' success partially depends on their properties like size, shape, porosity, and presence of heteroatoms, which can be controlled by selecting the proper type of biomass, activating agent, and preparation method. It is noted that different species of plants have different chemical compositions and textures. This mini-review summarizes our group's recent sophisticated developments in agricultural-bio-waste-derived carbonaceous materials, including nanomaterials for electrocatalytic water splitting, electrochemical sensors, supercapacitors, water splitting, water treatment, gas separation, and enhance oil recovery. This offers valuable insights and essential guidelines towards the future design of agro-waste derived carbonaceous materials in various applications. Bangladesh J. Plant Taxon. 27(2): 467-478, 2020 (December)

NanoMIP-based approach for the suppression of interference signals in electrochemical sensors

The Analyst ◽  
2019 ◽  
Vol 144 (24) ◽  
pp. 7290-7295
Author(s):  
Riccardo Rapini ◽  
Francesco Canfarotta ◽  
Elisabetta Mazzotta ◽  
Cosimino Malitesta ◽  
Giovanna Marrazza ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Electrochemical Sensors ◽  
Molecularly Imprinted ◽  
Interference Signals ◽  
Masking Agents ◽  
Molecularly Imprinted Nanoparticles ◽  
Target Analyte

Herein, we describe the use of molecularly imprinted nanoparticles (nanoMIPs) as sequestering (masking) agents, to suppress the signal coming from interfering molecules and facilitate the electrochemical detection of the target analyte.

Three-dimensional hydrogel-modified indium tin oxide electrode with enhanced performance for in situ electrochemical detection of extracellular H2O2

The Analyst ◽  
2021 ◽  
Author(s):  
Shiying Zhou ◽  
Xianfeng Wang ◽  
Liuyi Jiang ◽  
Human Sun ◽  
Danqun Huo ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Electrochemical Detection ◽  
Tin Oxide ◽  
Indium Tin Oxide ◽  
Electrochemical Sensors ◽  
Three Dimensional ◽  
Oxide Electrode ◽  
Indium Tin Oxide Electrode ◽  
H2o2 Reduction

Two different electrochemical sensors (Hemin-G4/Au/GCE and Hemin-G4/Au/ITO) were developed and applied to explore the electrocatalytic capacity of H2O2 reduction. Due to the excellent catalytic activity of Hemin-G4 and the high...

Application of Graphene-Based Nanocomposites in Electrochemical Detection of Heavy Metal Ions

2020 ◽  
Vol 12 (3) ◽  
pp. 435-440 ◽  
Author(s):  
Xue Chen ◽  
Yongcun Pei
Keyword(s):  
Heavy Metal ◽  
Metal Ions ◽  
Electrochemical Detection ◽  
Heavy Metal Ions ◽  
Electrochemical Sensors ◽  
Graphene Oxides ◽  
Experimental Conditions ◽  
Reduced Graphene ◽  
Reduced Graphene Oxides ◽  
Interference Tests

The purpose of this study was to explore the application of graphene-based nanocomposites in electrochemical detection of heavy metal ions. In this study, Graphene oxide (GO) was synthesized with improved Hummers method, and flower-like MoS2/rGO nanocomposite was synthesized with hydrothermal method and used as electrode modification material. In addition, scanning electron microscopy (SEM) and X-ray images were used to observe the characterization of the prepared samples and to detect the sensitivity of four heavy metal ions under optimal experimental conditions. The results showed that the reduced graphene oxides were coated with a large number of flower-like MoS2 and laid on the reduced graphene oxides. And in electrochemical experiments, adsorption experiments and interference tests, MoS2/rGO nanocomposites showed satisfactory performance for Pb(II). Therefore, this study provided a new strategy for the development of new nanocomposites composites as electrochemical sensors to detect the heavy metal ions in the aquatic environment.

scholarly journals How to Improve the Performance of Electrochemical Sensors via Minimization of Electrode Passivation

Chemosensors ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 12
Author(s):  
Jiri Barek
Keyword(s):  
Electrode Surface ◽  
Electrode Materials ◽  
Electrochemical Sensors ◽  
Critical Evaluation ◽  
Reaction Products ◽  
Rotating Disc ◽  
Surface Renewal ◽  
Practical Applications ◽  
Real Sample Analysis ◽  
Electrode Passivation

It follows from critical evaluation of possibilities and limitations of modern voltammetric/amperometric methods that one of the biggest obstacles in their practical applications in real sample analysis is connected with electrode passivation/fouling by electrode reaction products and/or matrix components. This review summarizes possibilities how to minimise these problems in the field of detection of small organic molecules and critically compares their potential and acceptability in practical laboratories. Attention is focused on simple and fast electrode surface renewal, the use of disposable electrodes just for one and/or few measurements, surface modification minimising electrode fouling, measuring in flowing systems, application of rotating disc electrode, the use of novel separation methods preventing access of passivating particles to electrode surface and the novel electrode materials more resistant toward passivation. An attempt is made to predict further development in this field and to stress the need for more systematic and less random research resulting in new measuring protocols less amenable to complications connected with electrode passivation.

scholarly journals Electrochemical Detection of Adrenaline and Hydrogen Peroxide on Carbon Nanotube Electrodes

2021 ◽  
Author(s):  
Gaurang Khot ◽  
Mohsin Kaboli ◽  
Tansu Celikel ◽  
Neil Shirtcliffe
Keyword(s):  
Carbon Nanotubes ◽  
Hydrogen Peroxide ◽  
Carbon Nanotube ◽  
Electrochemical Detection ◽  
Electrochemical Sensors ◽  
Carbon Electrodes ◽  
Cyclic Voltammetric ◽  
Highly Sensitive

Adrenaline and hydrogen peroxide have neuromodulatory functions in the brain.Considerable interest exists in developing electrochemical sensors that can detect their levels in vivo due to their important biochemical roles. Challenges associated with electrochemical detection of hydrogen peroxide and adrenaline are that the oxidation of these molecules usually requires highly oxidising potentials (beyond 1.4V vs Ag/AgCl) where electrode damage and biofouling are likely and the signals of adrenaline, hydrogen peroxide and adenosine overlap. To address these issues we fabricated pyrolysed carbon electrodes coated with oxidised carbon nanotubes (CNTs). Using these electrodes for fast-scan cyclic voltammetric (FSCV) measurements showed that the electrode offers reduced overpotentials compared with graphite and improved resistance to biofouling. The Adrenaline peak is reached at 0.75 V and reduced back at -0.2 V while hydrogen peroxide is detected at 0.85V on this electrode. The electrodes are highly sensitive with a sensitivity of16nA microM-1 for Adrenaline and 11nA microM-1 for hydrogen peroxide on an 80 micro m2 electrode. They are also suitable to distinguish between adrenaline, hydrogen peroxide and adenosine thus these probes can be used for multimodal detection of analytes.

DNA Electrochemistry and Electrochemical Sensors for Nucleic Acids

2018 ◽  
Vol 11 (1) ◽  
pp. 197-218 ◽  
Author(s):  
Elena E. Ferapontova
Keyword(s):  
Nucleic Acids ◽  
Bacterial Contamination ◽  
Environmental Science ◽  
Genetically Modified Organisms ◽  
Electrochemical Sensors ◽  
Fast Analysis ◽  
Basic Principles ◽  
Practical Applications ◽  
Analytical Platforms ◽  
Dna Electrochemistry

Sensitive, specific, and fast analysis of nucleic acids (NAs) is strongly needed in medicine, environmental science, biodefence, and agriculture for the study of bacterial contamination of food and beverages and genetically modified organisms. Electrochemistry offers accurate, simple, inexpensive, and robust tools for the development of such analytical platforms that can successfully compete with other approaches for NA detection. Here, electrode reactions of DNA, basic principles of electrochemical NA analysis, and their relevance for practical applications are reviewed and critically discussed.

Selective Nanomolar Electrochemical Detection of Serotonin, Dopamine and Tryptophan Using TiO2/RGO/CPE - Influence of Reducing Agents

2021 ◽  
Author(s):  
Teena Joseph ◽  
Jasmine Thomas ◽  
Tony Thomas ◽  
Nygil Thomas
Keyword(s):  
Hydrothermal Method ◽  
Electrochemical Detection ◽  
Electrochemical Sensors ◽  
Reducing Agents ◽  
One Pot

TiO2/RGO nanocomposites were synthesised by a simple one pot hydrothermal method. The influence of different reducing agents on the composite preparation was systematically studied. Electrochemical sensors were developed using the...

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