Ruthenium(ii) complexes with dppz: from molecular photoswitch to biological applications

2016 ◽  
Vol 45 (34) ◽  
pp. 13261-13276 ◽  
Author(s):  
Guanying Li ◽  
Lingli Sun ◽  
Liangnian Ji ◽  
Hui Chao

The present article describes the recent advances in biological applications of the Ru-dppz systems in DNA binding, cellular imaging, anticancer drugs, phototherapy, protein aggregation detecting and chemosensors.

2017 ◽  
Vol 46 (47) ◽  
pp. 16357-16380 ◽  
Author(s):  
Lawrence Cho-Cheung Lee ◽  
Kam-Keung Leung ◽  
Kenneth Kam-Wing Lo

This Perspective summarizes recent advances in the biological applications of luminescent rhenium(i) tricarbonyl polypyridine complexes.


Author(s):  
Shukla PK ◽  
Singh MP ◽  
Patel R

Indole and its derivatives have engaged a unique place in the chemistry of nitrogen heterocyclic compounds. The recognition of the plant growthhormone, heteroauxin, the significant amino acids, tryptamine & tryptophan and anti-inflammatory drug, indomethacine are the imperativederivatives of indole which have added stimulus to this review work. Isatin (1H-indole-2,3-dione), an indole derivative of plant origin. Althoughit is a naturally occurring compound, but was synthesized by Erdmann and Laurent in 1840 before it was found in nature. Isatin is a versatileprecursor for many biologically active molecules and its diversified nature makes it a versatile substrate for further modifications. It is concernedin many pharmacological activities like anti-malarial, antiviral, anti-allergic, antimicrobial etc; isatin and its derivatives have been also found todemonstrate promising outcomes against various cancer cell lines. This review provides a brief overview on the recent advances and futureperspectives on chemistry and biological aspects of isatin and its derivatives reported in the recent past.


2021 ◽  
Vol 57 (16) ◽  
pp. 1989-2004
Author(s):  
Junyong Sun ◽  
Qiang Zhang ◽  
Xiaomei Dai ◽  
Pinghua Ling ◽  
Feng Gao

We summarize the recent advances in engineering approaches to obtain functionalized semiconducting polymer nanoparticles (SPNs) for biological applications. The challenges and outlook of fabricating functionalized SPNs are also provided.


Author(s):  
Guizhu Wu ◽  
Jingyu Sun ◽  
Ze Zhang ◽  
Donggang Guo ◽  
Jiandang Liu ◽  
...  

Quantum dots (QDs) have shown promising potential to many biomedical and biological applications, mainly in drug delivery or activation and cellular imaging. These semiconductor nanoparticles, QDs, whose particle size is in the range of 2-10 nanometer with unique photo-chemical and -physical properties that are not possessed by any other isolated molecules, have become one of the distinct class of imaging probes and worldwide platforms for manufacturing of multifunctional nanodevices. In this chapter, properties, applications of QDs, and importance in the biomedical field especially in drug delivery is presented.


2019 ◽  
Vol 2019 ◽  
pp. 1-18 ◽  
Author(s):  
Ayodele T. Odularu ◽  
Peter A. Ajibade ◽  
Johannes Z. Mbese ◽  
Opeoluwa O. Oyedeji

Platinum-group (PG) complexes have been used as antibacterial and anticancer agents since the discovery of cisplatin. The science world still requires improvement on these complexes because of multidrug and antineoplastic resistances. This review observes discoverers and history of these platinum-group metals (PGMs), as well as their beneficial applications. The focus of this study was biological applications of PGMs in relation to human health. Sandwich and half-sandwich PGM coordination compounds and their metal nanoparticles give improved results for biological activities by enhancing efficient delivery of both antibacterial and anticancer drugs, as well as luminescent bioimaging (biomarkers) for biological identifications.


2019 ◽  
Vol 50 (3) ◽  
pp. 261-270 ◽  
Author(s):  
Phuong Tran ◽  
Sang-Eun Lee ◽  
Dong-Hyun Kim ◽  
Yong-Chul Pyo ◽  
Jeong-Sook Park

2020 ◽  
Vol 8 (36) ◽  
pp. 8219-8231
Author(s):  
Wumaier Yasen ◽  
Ruijiao Dong ◽  
Aliya Aini ◽  
Xinyuan Zhu

Supramolecular block copolymers with a dynamically reversible nature and hierarchical microphase-separated structures can greatly enrich the library of pharmaceutical carriers and outline future research directions for biological applications.


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