Preparation and properties of ZnO/sodium alginate bi-layered hydrogel films as novel wound dressings

2019 ◽  
Vol 43 (22) ◽  
pp. 8684-8693 ◽  
Author(s):  
Tingting Wang ◽  
Jinqing Wang ◽  
Rui Wang ◽  
Peilin Yuan ◽  
Zengjie Fan ◽  
...  
Keyword(s):  
Sodium Alginate ◽  
Wound Dressings ◽  
Natural Material ◽  
Biomedical Field ◽  
Hydrogel Films

As one kind of natural material, alginate has been widely investigated and used in the biomedical field.

scholarly journals Composite Polyvinylpyrrolidone–Sodium Alginate—Hydroxyapatite Hydrogel Films for Bone Repair and Wound Dressings Applications

Polymers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 3989
Author(s):  
Inna V. Fadeeva ◽  
Elena S. Trofimchuk ◽  
Anna A. Forysenkova ◽  
Abdulrahman I. Ahmed ◽  
Oleg I. Gnezdilov ◽  
...  
Keyword(s):  
Sodium Alginate ◽  
Bone Repair ◽  
Composite Films ◽  
The Body ◽  
Wound Dressings ◽  
Ex Situ ◽  
Polymer Mixture ◽  
Swelling Properties ◽  
Hydrogel Films

Today, the synthesis of biocompatible and bioresorbable composite materials such as “polymer matrix-mineral constituent,” which stimulate the natural growth of living tissues and the restoration of damaged parts of the body, is one of the challenging problems in regenerative medicine. In this study, composite films of bioresorbable polymers of polyvinylpyrrolidone (PVP) and sodium alginate (SA) with hydroxyapatite (HA) were obtained. HA was introduced by two different methods. In one of them, it was synthesized in situ in a solution of polymer mixture, and in another one, it was added ex situ. Phase composition, microstructure, swelling properties and biocompatibility of films were investigated. The crosslinked composite PVP-SA-HA films exhibit hydrogel swelling characteristics, increasing three times in mass after immersion in a saline solution. It was found that composite PVP-SA-HA hydrogel films containing HA synthesized in situ exhibited acute cytotoxicity, associated with the presence of HA synthesis reaction byproducts—ammonia and ammonium nitrate. On the other hand, the films with HA added ex situ promoted the viability of dental pulp stem cells compared to the films containing only a polymer PVP-SA blend. The developed composite hydrogel films are recommended for such applications, such as membranes in osteoplastic surgery and wound dressing.

scholarly journals Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections

Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1682 ◽  
Author(s):  
Bogdan Stefan Vasile ◽  
Alexandra Catalina Birca ◽  
Mihaela Carmen Musat ◽  
Alina Maria Holban
Keyword(s):  
Silver Nanoparticles ◽  
Essential Oils ◽  
Sodium Alginate ◽  
Dip Coating ◽  
Wound Dressings ◽  
Wound Management ◽  
Coating Method ◽  
Efficient Alternative ◽  
Ft Ir ◽  
Dip Coating Method

Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management.

Swelling Characterization of Double Sensitive Hydroxypropylcellulose / Sodium Alginate Hydrogel

2011 ◽  
Vol 221 ◽  
pp. 184-188
Author(s):  
Guo Li Gong ◽  
Hui Li ◽  
Zhen Hua Guo
Keyword(s):  
Sodium Alginate ◽  
Temperature Sensitivity ◽  
Ph Value ◽  
Natural Material ◽  
Swelling Ratio ◽  
Ph Responsive ◽  
Alginate Hydrogel ◽  
Maximum Value ◽  
Responsive Hydrogels

A series of temperature and pH responsive hydrogels was synthesized by using hydroxypropylcellulose (HPC) as temperature sensitivity material and the natural material, sodium alginate (SA) as pH sensitivity material. The effect of SA to LCST has been studied and the mechanism of the influence has been presented. In addition, the swelling ratio and controlling factor of swelling process were all researched in this paper. The main results obtained are as follows: the LCST decreased gradually as added SA into HPC; the HPC/SA hydrogel responded both temperature and pH value of the medium; the swelling ratio reached maximum value as pH value of 6.

scholarly journals Application of blocking and immobilization of electrospun fiber in the biomedical field

RSC Advances ◽  
2020 ◽  
Vol 10 (61) ◽  
pp. 37246-37265
Author(s):  
Yuanlan Ning ◽  
Wen Shen ◽  
Fen Ao
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Drug Delivery Systems ◽  
Electrospun Fiber ◽  
Delivery Systems ◽  
Wound Dressings ◽  
Biomedical Field

The unique blocking and immobilization of electrospinning nanofibers play an important role in tissue engineering, wound dressings, drug delivery systems and other fields.

scholarly journals Synthesis and characterization of polymeric responsive CMC/Pectin hydrogel films loaded with Tamarix aphylla extract as potential wound dressings

BIOCELL ◽  
2021 ◽  
Vol 45 (5) ◽  
pp. 1273-1285
Author(s):  
BARKAT ALI KHAN ◽  
FAZAL KARIM ◽  
MUHAMMAD KHALID KHAN ◽  
FAHEEM HAIDER ◽  
SADIQULLAH KHAN
Keyword(s):  
Wound Dressings ◽  
Synthesis And Characterization ◽  
Hydrogel Films

scholarly journals PREPARATION AND CHARACTERIZATION OF CHITOSAN-AGAR FILMS

2020 ◽  
Vol XXV ◽  
pp. 210-226
Author(s):  
Joanna Wolska ◽  
Joanna Setkowicz ◽  
Irena H. Maliszewska
Keyword(s):  
Honey Bee ◽  
Weight Ratio ◽  
Wound Dressings ◽  
Bee Pollen ◽  
Molecular Weights ◽  
Honey Solution ◽  
Hydrogel Films

Hydrogel films composed of chitosan and agar or chitosan, agar and honey/bee pollen were prepared; they could be used as active wound dressings. During this study, various types of gel films were prepared using chitosan with different molecular weights and ratios of the two biopolymers. In addition, compositions with different amounts of honey or bee pollen were obtained. The selected samples were characterized by determining typical properties that are important for wound dressings. The best twocomponent films had a chitosan to agar weight ratio of 2:1. From among the examined tri-component films, the 2:1:0.5 weight ratio of chitosan, agar and 50 wt% honey solution was the best composition.

Sodium alginate/poly(vinyl alcohol)/nano ZnO composite nanofibers for antibacterial wound dressings

2011 ◽  
Vol 49 (3) ◽  
pp. 247-254 ◽  
Author(s):  
K.T. Shalumon ◽  
K.H. Anulekha ◽  
Sreeja V. Nair ◽  
S.V. Nair ◽  
K.P. Chennazhi ◽  
...  
Keyword(s):  
Sodium Alginate ◽  
Vinyl Alcohol ◽  
Composite Nanofibers ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
Nano Zno

scholarly journals Comparison of the Morphological and Physical Properties of Different Absorbent Wound Dressings

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Sukhontha Hasatsri ◽  
Anuphap Pitiratanaworanat ◽  
Suwit Swangwit ◽  
Chadaporn Boochakul ◽  
Chamaipond Tragoonsupachai
Keyword(s):  
Physical Properties ◽  
Sodium Alginate ◽  
Water Vapour ◽  
Transmission Rate ◽  
Wound Dressings ◽  
Original Structure ◽  
Absorption Properties ◽  
Vapour Permeability ◽  
Polyurethane Film ◽  
Film Layer

Good quality wound dressings should have exceptional properties for usage, such as being able to remove excess wound exudates, having rapid dehydration, and providing optimal water vapour permeability. This study evaluated and compared the morphological and physical properties of six different commercially absorbent wound dressings in Thailand: two hydrocolloids, two alginates, and two foams. These wound dressings are available in a variety of components and structures, some of which have a multilayer structure. The results showed that the calcium sodium alginate dressings had better absorption properties than the calcium alginate dressings, hydrocolloid dressings, hydrocolloid with foam layer dressings, foam with polyurethane film layer dressings, and foam with hydrogel and polyurethane film layer dressings. Furthermore, the calcium sodium alginate dressings had the highest rate of dehydration and provided an optimal water vapour transmission rate. However, the calcium sodium alginate dressings could not retain the original structure after being submerged with a wound exudate.

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