scholarly journals Transplantation of an alpine Carex-fen – a mitigation measure related to the construction of a reservoir in the Austrian Alps

2021 ◽  
Vol 31 ◽  
pp. 00036
Author(s):  
Martin Schletterer ◽  
Brigitte Kurz ◽  
Alexandra Schönegger ◽  
Gregory Egger ◽  
Klaus Feistmantl
Keyword(s):  
Vegetation Type ◽  
Donor Site ◽  
Mitigation Measures ◽  
Target Area ◽  
Hydropower Project ◽  
Austrian Alps ◽  
Initial Area ◽  
First Results ◽  
One Year ◽  
Basic Infrastructure

Translocations are applied in the context of infrastructure projects to preserve certain vegetation types. Within the EIA of a large hydropower project in the Austrian Alps, manifold mitigation measures were defined. Among those, the transplantation of about 1.4 ha Carex-fen at an altitude of about 2000 m was defined. One year before the start of the construction works in 2021, basic infrastructure (roads) was established and different ecological measures were undertaken, e.g. translocation of amphibians to newly constructed habitats as well as the transplantation of the Carex-fen. The turf was cut from the initial area with an adjusted excavator shovel, delivered to a wheel loader which brought each single turf immediately to the target area, where another excavator mounted the turf in a pre-arranged area. At the donor site more than ½ of the area was based on wet gley, while especially areas in the vicinity of the river were based on fluvial gravel. With the 30 to 70 cm thick turfs also animals, e.g. Odonata, were transferred. Before the translocation a monitoring of the donor sites was carried out. The monitoring concept foresees a detailed monitoring of the newly established sites for 10 years. Herein we provide insights in the applied technology and summarize first results of the monitoring. Overall, our project is unique regarding the vegetation type, the technology, the size and the intensity of monitoring.

scholarly journals Technical Note: Evaluation of simultaneous measurements of mesospheric OH, HO<sub>2</sub>, and O<sub>3</sub> under photochemical equilibrium assumption: Statistical approach

2017 ◽  
Author(s):  
Mikhail Yu. Kulikov ◽  
Anton A. Nechaev ◽  
Mikhail V. Belikovich ◽  
Tatiana S. Ermakova ◽  
Alexander M. Feigin
Keyword(s):  
Transport Model ◽  
Full Range ◽  
Lower Thermosphere ◽  
Technical Note ◽  
Primary Data ◽  
Chemical Transport Model ◽  
Air Concentration ◽  
Simultaneous Measurements ◽  
First Results ◽  
One Year

Abstract. The Technical Note presents a statistically correct approach to evaluating simultaneous measurements of several atmospheric components under the assumption of photochemical equilibrium. We consider simultaneous measurements of OH, HO2, and O3 at the altitudes of the mesosphere as a specific example and their daytime photochemical equilibrium as an evaluating relationship. A simplified algebraic equation relating local concentrations of these components in the 50–100 km altitude range has been derived. The parameters of the equation are air temperature, air concentration, local zenith angle, and the rates of 9 reactions. We have performed one-year simulation of the mesosphere and lower thermosphere using a 3D chemical-transport model. The simulation shows that the discrepancy between the calculated evolution of the components and the equilibrium value given by the equation does not exceed 3–4 % in the full range of altitudes independent of season or latitude. We have developed the technique of statistic Bayesian evaluation of simultaneous measurements of OH, HO2 and O3 based on the equilibrium equation taking into account the measurement error. The first results of application of the technique to MLS/Aura data are presented in this Technical Note. It has been found that the satellite data of HO2 distribution regularly demonstrates essentially lower altitudes of mesospheric maximum of this component. This has also been confirmed by offline retrieval of HO2 from the MLS primary data.

scholarly journals First Results from the Submillimeter Wave Astronomy Satellite – H2O and O2 Discoveries

2000 ◽  
Vol 197 ◽  
pp. 161-174
Author(s):  
Gary J. Melnick
Keyword(s):  
Interstellar Medium ◽  
Ground State ◽  
Molecular Clouds ◽  
Submillimeter Wave ◽  
Important Species ◽  
First Results ◽  
One Year

The Submillimeter Wave Astronomy Satellite (SWAS) was successfully launched on 5 December 1998 with the goals of studying: (1) the distribution of oxygen in the interstellar medium; (2) the role of H2O and O2 as gas coolants; and (3) the UV-illuminated surfaces of molecular clouds. To achieve these goals, SWAS is conducting pointed observations of dense (n(H2) > 103 cm–3) molecular clouds throughout our Galaxy in either the ground-state or a low-lying transition of five astrophysically important species: H2O, H218O, O2, CI, and 13CO. SWAS has made great strides in each of these areas of investigation. This paper will summarize our H2O and O2 findings one year into the mission.

96 Treatment of Donor Sites in Large TBSA Burn Injuries with an Autologous Skin Cell Suspension Supports Early Reharvesting

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S62-S63
Author(s):  
Kevin N Foster ◽  
James H Holmes ◽  
William L Hickerson ◽  
Jeffrey W Shupp ◽  
Robert Sheridan ◽  
...  
Keyword(s):  
Adverse Events ◽  
Cell Suspension ◽  
Point Of Care ◽  
Donor Site ◽  
Burn Injuries ◽  
Severe Injuries ◽  
Skin Cell ◽  
Skin Loss ◽  
One Year ◽  
Delayed Closure

Abstract Introduction Treatment of large TBSA burn injuries is often limited by donor site availability and requires reharvesting to obtain definitive closure. Patients with severe injuries may have delayed closure compared to uncompromised patients that typically have their donor sites healed in 7–14 days. Autologous skin cell suspension (ASCS) can be prepared to treat burn wounds at the point-of-care. The safety and effectiveness have not yet been established for use in the treatment of donor sites. This study presents the use of ASCS for the treatment of donor sites in patients with life-threatening burn injuries that were enrolled in a prospective uncontrolled observational study (IDE 15945—NCT02992249). Methods ASCS was applied to the donor site after harvesting of STSGs. Clinical outcomes out to one year were evaluated including percentage of re-epithelialization, long-term cosmetic outcomes, and adverse events. Results Ninety-six subjects from 22 burn centers had their donor sites treated with ASCS as part of their treatment regimen. The average subject age was 30.1 and the average TBSA injury was 53.7 ±17.3%. The mean Baux score was 89.2 with 36% of subjects having a score greater than 100. Collectively, 528 donor sites were individually treated. In this compromised patient population 37.5% were ≥95% re-epithelialized by week 1 (n=435), and by week 2, 82.7% of the donor sites were ≥95% re-epithelialized (n=434), regardless of how many times they were harvested. Approximately 19% of the donor sites treated with ACSC were reharvested multiple times following initial healing (15% two times, 2.3% three times, and 7 donor sites were harvested 4 times) and retreated. Of donor sites harvested more than once, 39.3% (n=84), 81% (n=79), and 85.7% (n=77) of sites were ≥ 95% re-epithelialized by week 1, 2 and 4, respectively. One-year data was available for 427 donor sites and the majority had matched or mildly mismatched color, pigment, and texture. Adverse events included one site with a hematoma, one patient with donor sites that had fragile skin loss secondary to traumatic friction, one patient with active bleeding, two patients with anemia secondary to donor site bleeding, one patient with delayed closure due to mild infection of staph species. All AEs were unlikely or unrelated to the device. Conclusions ASCS has been successfully used to achieve closure of donor site wounds without significant safety risk in patients with extensive burn injuries. Applicability of Research to Practice Application of ASCS for donor site healing may be particularly relevant for patients with large burn injuries requiring subsequent reharvesting to achieve definitive closure.

One year effect of anastrozole and risedronate on bone mineral density: First results from the IBIS-II bone sub-study

Bone ◽  
2011 ◽  
Vol 48 (1) ◽  
pp. S24 ◽  
Author(s):  
S. Singh* ◽  
J. Cuzick ◽  
G.M. Blake ◽  
D. Mesher ◽  
R. Patel ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Year Effect ◽  
First Results ◽  
One Year

Pedicled Oblique Para-Umbilical Perforator (OPUP) Flap for Upper Limb Reconstruction

2016 ◽  
Vol 21 (02) ◽  
pp. 229-233
Author(s):  
Praveen Naduthodikayil ◽  
Laxminarayan Bhandari ◽  
Sreelesh Lalitha Sreedhar
Keyword(s):  
Upper Limb ◽  
Donor Site ◽  
Good Alternative ◽  
The Past ◽  
Groin Flap ◽  
Major Disadvantage ◽  
One Year ◽  
Proximal Forearm ◽  
Upper Limb Reconstruction ◽  
Scar Hypertrophy

Background: Groin flap has been considered the workhorse flap for hand reconstruction. However it has certain drawbacks when covering defects over elbow or proximal forearm. Pedicled oblique paraumbilical perforator (OPUP) based flaps provide a good alternative in such cases. Methods: We performed OPUP flap in 11 cases of complex upper limb reconstructions over the past one year. We report our experience with this flap. Results: All flaps survived. One patient had marginal necrosis of 1 cm in the proximal end after flap division. Three patients had donor site scar hypertrophy. Conclusions: OPUP flap is superior to groin flap for larger defects or defects around the elbow. The major disadvantage is the donor site scar which is prone to hypertrophy.

scholarly journals Monte Carlo Simulation and Modeling of Schedule, Cost and Risks of Dasu Hydropower Project

2019 ◽  
Vol 38 (3) ◽  
pp. 557-570
Author(s):  
Sajjad Mubin ◽  
Shah Jahan ◽  
Ekaterina Gavrishyk
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Mitigation Measures ◽  
Simulation And Modeling ◽  
Hydropower Project ◽  
Successful Completion ◽  
Mitigation Measure ◽  
Risk Sensitive ◽  
Potential Risks ◽  
Made In

HPP (Hydropower Projects) are very complex and risky in nature. For HPP, it is extremely important not only to identify risks but also to adopt proper mitigation measure to complete the project with in defined schedule and budget. Attempt has been made in this paper to identify critical risks associated with Dasu HPP and their mitigation measure to complete the project within predefined time and budget. The research methodology involved the questionnaire survey for identification of potential risks with their probabilities and impact. Pert-Master (Oracle Risk) software was used for simulation purposes. After feeding all data in the software, Monte Carlo simulation was run at 1,000 iterations to generate most probable duration of project, most probable cost of the project, critical risks sensitive to duration, critical risk sensitive to cost and statistically analyzed critical tasks/activities, which need due consideration for successful completion of project. Simulated schedule and budget was compared with planned one to find possible deviations, which may be eliminated by using mitigation measures proposed in the last section of the paper.

scholarly journals Epidemiological Assessment of the First Results of the National Program of Immunization of Young Children against Pneumococcal Infection in Russia

2017 ◽  
Vol 16 (5) ◽  
pp. 16-21 ◽  
Author(s):  
N. I. Brico ◽  
N. N. Tsapkova ◽  
V. A. Sukhova ◽  
A. N. Gerasimov ◽  
R. V. Polybin ◽  
...  
Keyword(s):  
Young Children ◽  
Pneumococcal Infection ◽  
Statistical Processing ◽  
Causal Connection ◽  
Pneumococcal Infections ◽  
Non Invasive ◽  
National Immunization ◽  
First Results ◽  
Analytical Research ◽  
One Year

Pneumococcal infections are among the most common infections are an important cause of morbidity and mortality worldwide, including Russia. At the end of 2014 in the national immunization schedule countries introduced vaccination against pneumococcal infection The aim of study. To assess the epidemiological effectiveness of vaccination against pneumococcal infection in young children selectively in different territories of the Russian Federation 2 years later from its beginning Materials and methods. In the course of epidemiological observational analytical research of type «case-control» data were obtained on the incidence in vaccinated and unvaccinated against pneumococcal infection in children from 2 months to 2 years We analyzed 1422 outpatients and 356 case histories of children in several cities (Moscow, Smolensk, Sevastopol, Perm, Tyumen, Barnaul). The results are subjected to statistical processing The results and discussion Established that there is a reliable causal connection between the lack of vaccination of children against pneumococcal infection and incidence of diseases. Shows high prophylactic efficacy of vaccination of children up to 2 years. Received in outpatient and inpatient facilities, evidence suggests that the incidence of invasive and non-invasive forms of pneumococcal infection was significantly lower in the vaccinated children It was revealed that the vaccination coverage against pneumococcal infection in children from 2 months to one year and the second year of life was 51 and 40% respectively. Vaccination in the first six months of life in 2016 received only 25% of children. A high proportion of the parent's refusal of vaccination of children (54.2%), and high frequency medical taps (9.7%) from vaccination.

scholarly journals Managing lip large papilloma extirpation defect by arterialized advancement vermilion flap

2020 ◽  
Vol 7 (7) ◽  
pp. 2442
Author(s):  
Rahul Sahai ◽  
Sudhir Singh
Keyword(s):  
Close Association ◽  
Verrucous Carcinoma ◽  
Donor Site ◽  
Advancement Flap ◽  
Surgical Removal ◽  
Upper Lip ◽  
Lower Lip ◽  
Aesthetic Results ◽  
One Year ◽  
Lip Defect

The close resemblance of squamous papilloma with verrucous carcinoma and the chief etiological factor associated with its development, the human papillomavirus (HPV) raises a doubt about its close association with malignancy. The best way to treat HPV growths is surgical removal and assessment of lesion by histopathology. The defect needs reconstruction with full function and aesthetic outlook. Thirty-seven years old young man with history of tobacco chewing developed slow growing papilloma in upper lip in one year. It was excised fully and the defect was repaired by arterialized lip vermilion mucosal flap based on slightly tortuous labial vessel and so the flap could be elastically stretched even up to fifty percent of lip length and applied successfully. Same patient developed papilloma in lower lip as a separate primary after two years of nonrecurrence of previous operated upper lip papilloma. Lower lip lesion was excised similarly and repaired with same type of vermilion mucosal advancement flap from adjacent part of lower lip defect created. The post-operative period was uneventful and after three years of last operation there is no recurrence in either lip. Vermilion flap which is based on labial artery containing composite tissue comprising of mucosa and portion of orbicularis muscle mainly has been utilized to reconstruct the post excision papilloma lip defect with excellent functional and aesthetic results. There was no microstomia. It is single stage not involving donor site like tongue or cheek mucosa and is good upto half of lower lip defects.

scholarly journals CTNI-46. A PHASE II TRIAL OF TUMOR TREATING FIELDS (TTFIELDS) CONCOMITANT WITH RADIOSURGERY FOR THE TREATMENT OF RECURRENT, BEVACIZUMAB-NAÏVE GLIOBLASTOMA

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii52-ii53
Author(s):  
Maciej Harat ◽  
Maciej Blok ◽  
Magda Adamczak-Sobczak ◽  
Pawel Szymanski ◽  
Iza Miechowicz ◽  
...  
Keyword(s):  
Phase Ii ◽  
Phase Ii Trial ◽  
Methylation Status ◽  
Historical Control ◽  
Phase Iii ◽  
Maximum Diameter ◽  
Target Area ◽  
Open Label ◽  
Fet Pet ◽  
One Year

Abstract BACKGROUND Almost all GBM patients experience recurrent disease, and median survival after recurrence is 6 months. A phase III trial conducted to test safety and efficacy of TTFields alone versus chemotherapy (including bevacizumab) in recurrent GBM showed improved PFS at six months and one-year survival was 20% in both treatment arms. Stereotactic radiosurgery (SRS), another treatment option recommended at recurrence, has limitations due to the invasive nature of glioblastoma. TTFields may decrease the tumor aggressiveness outside the target area potentially by multiple pathways, including immunogenic cell death and DNA repair inhibition sensitizing to radiation. We hypothesize that combined SRS and TTFields will be complementary, improving outcomes with minimal toxicity. METHODS In this open-label, phase II trial 40 participants with recurrence will be treated with SRS and TTFields, starting in 2020. Recurrence will be defined on FET-PET or MRI using RANO criteria. At least 6 months between the end of the first course of radiotherapy and SRS is mandatory with recurrent tumor visible on FET-PET and/or MRI, with the maximum diameter &lt; 5 cm by either technique. SRS must be delivered within 7 days of TTFields start. A 5-day SRS regimen is allowed. TTFields should be interrupted only during SRS. The sample size of the study was calculated for the comparison of survival against a historical control. With 40 patients followed until death, there is at least an 80% ability to detect a 19% difference in one-year survival rate and 17% difference in ORR (p=0.05) compared to the EF-11 clinical trial. The one-year survival and ORR rate were seen in 20% and 14% of TTFields patients in the historical control. Overall survival will be stratified by volume, PET-based treatment, SVZ invasion, MGMT methylation status, time to first progression, and TTFields compliance. Estimated study primary completion date is July 2023.

Sinkhole collapse and hydrogeological hazard assessment in covered karst terrains: Case study of a bridge project across the Loire River (Orleans, France)

2020 ◽  
Author(s):  
Gildas Noury ◽  
Damien Salquèbre ◽  
Thomas Jacob ◽  
Jean-Michel Baltassat ◽  
Fawzia Asfirane-Haddadj ◽  
...  
Keyword(s):  
Hazard Assessment ◽  
Gamma Ray ◽  
Mitigation Measures ◽  
Alluvial Deposits ◽  
Dye Tracing ◽  
Cave System ◽  
Prone Area ◽  
First Results ◽  
Covered Karst ◽  
Loire River

&lt;p&gt;The floodplain of the Loire River around Orleans is a sinkhole-prone area due to the highly karstified calcareous Beauce Formation overlying by few meters of weathered materials and alluvial deposits. Such layout makes it necessary to carry out detailed geotechnical and hydrogeological investigations for any important building project.&lt;/p&gt;&lt;p&gt;This paper presents the first results of a study carried out by the French Geological Survey for a bridge project across the Loire River. The geological setting indicates that the study area is near the front door of a supposed-major cave system in which water, coming from the Loire River, not only provides drinking water for an important part of the region, but also supplies the main spring of the Loiret River, located a few kilometers further. The overview of past sinkhole collapses confirms that the study area is regularly concerned by ground collapses of several meters of diameter. Field investigations include microgravimetry (26 hectares), two electrical resistivity profiles (720 m and 470 m long), 149 cone penetration tests (around 15 m deep), a first sequence of 11 drillings (40 m deep) and videos, gamma-ray and sonar logs. A first sinkhole hazard assessment is now quite complete: very weak layers (possibly caves) of several decimeters to a few meters thick need specific mitigation measures to secure the construction project. Other investigations are still being analysed (a second sequence of drillings, dye tracing, injection of salt brine with resistivity profiling) and should help specify the area hydrogeological hazard.&lt;/p&gt;

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