scholarly journals Alzheimer in the City

OCL ◽  
2018 ◽  
Vol 25 (4) ◽  
pp. D402 ◽  
Author(s):  
Jean-François Dartigues

Alzheimer’s disease was described in 1906, but it was only in 1987 that it was recognized as a public health problem with the actions of patient family associations. Despite successive Alzheimer plans, it remains a neglected and under-diagnosed disease. The lack of curative treatment and a clash of views between general practitioners and specialists explain these findings. Paradoxically, despite this neglect, Alzheimer’s disease is receding in the city. This is the proof that prevention is possible.

CNS Spectrums ◽  
2009 ◽  
Vol 14 (S7) ◽  
pp. 4-7 ◽  
Author(s):  
Stephen Salloway

There are currently >5 million people in the United States who have been diagnosed with Alzheimer's disease. That prevalence rate is expected to triple as the population ages. The health and economic burden due to Alzheimer's disease is a worldwide problem, with some of the greatest burden coming from the developing world as people live longer in those societies. Throughout the world, the projected growth of Alzheimer's disease is dramatic. This is a worldwide public health problem of the highest order, and there is a compelling need to develop new treatments and methods of earlier diagnosis need to slow the progression of the disease and lessen its impact.


Author(s):  
A.P. Porsteinsson ◽  
E.D. Clark

Alzheimer’s disease (AD) remains one of our greatest unmet medical needs, without any approved disease-modifying therapies. The emotional and financial burden of AD is enormous and predicted to grow exponentially with increasing median population age, posing a major public health problem. The potential to prevent or improve cognitive decline due to AD has important implications. There are medications currently approved for symptomatic treatment of AD, but they have limited clinical benefits and do not change the ultimate trajectory of the disease. The need to find effective treatments for AD that can prevent, slow, arrest, or even reverse the disease is ever more urgent and interventions that delay the symptomatic onset of AD would have a major public health impact (1).


2006 ◽  
Vol 18 (2) ◽  
pp. 99-104 ◽  
Author(s):  
Maria Cristina Abraão Nachif

This is a case study of homicides carried out within the Second Section of the Justice Court, in Campo Grande, Mato Grosso do Sul, Brazil. It has been observed that: most homicides are carried out by males (95,7%), Afro-Brazilians (62,9%), between 15 and 25 years (45,7%), illiterate or with incomplete schooling (74,3%), and unemployed (18,6%). It was also observed that the victims' profiles are very similar. Most homicides take place on public streets (41,4%), in the city suburbs, between 20 and 24 o'clock, (51,4%). In 50,0% of the cases, the victim did not receive help from any public health service. In the cases where any family member helped (37,41%), the victims were taken to the Santa Casa de Misericórdia Hospital. Firearms were the prevailing weapons (70,0%) and motives for all crimes were futile, or banal; in most cases (57,0%), alcohol was involved.


Author(s):  
Rafael Brito-Aguilar

Dementia has become a major public health concern around the world. Dementia risk factors are significantly different among countries. The number of new cases of dementia anticipated each year worldwide is almost 7.7 million, one new case every four seconds. There are 3.6 million (46%) new cases per year in Asia, 2.3 million (31%) in Europe, 1.2 million (16%) in the Americas, and 0.5 million (7%) in Africa. Latin American and Caribbean low and middle-income countries are at high risk. Air pollution is an important risk modifiable factor for dementia across the world, and the recent report of the Alzheimer’s disease continuum in children and young adults residing in Metropolitan Mexico City along with the presence of cognitive impairment in 55% of the young adult population residing in Mexican cities with fine particulate matter concentrations above the current USEPA annual standard of 12 μg/m3 makes this a severe public health problem in progress. It is imperative to keep generating epidemiological data on dementia worldwide and their relationship with air pollutants to improve the strategies to face all the challenges associated with dementia and Alzheimer’s disease in particular. Alzheimer’s disease is a fatal disease, we have no cure, and we ought to invest in protecting our citizens by intervening in modifiable environmental factors.


F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 641
Author(s):  
Dayanna Hartmann Cambruzzi Mendes ◽  
Glaucia Renee Hilgemberg ◽  
Flavio Silva Posseti ◽  
Jéssica Wouk ◽  
Emerson Carraro

Introduction: Alzheimer's disease (AD) is a public health problem in Brazil due to the growing number of older adults in this population. Knowing the prevalence of AD in the Paraná state is essential to improve patients’ quality of life. The objective of the study was to estimate AD prevalence in the state of Paraná, based on the prescription of anticholinesterases, from 2012 to 2017. Methods: Patients diagnosed with AD, aged 60 years or over, who used Brazil’s Unified Public Health System (SUS) and received AD medication from the Department of Pharmaceutical Assistance of the state of Paraná, from 2012 to 2017, were the target population of the present study. The medication data were collected from the Computerized system management and Monitoring of Exceptional Drugs (SISMEDEX), and the population’s data were collected from the Brazilian Institute of Geography and Statistics (IBGE). Results: The sample consisted of 52,687 patients, and the median prevalence of AD in the established period for the state was 642.6/100,000 inhabitants (0.64%). In all ages and macro-regions, women showed the highest prevalence rates. The median prevalence for women in the established period was 755.4/100,000 inhabitants (0.75%). Among men, the median prevalence was 510.2/100,000 inhabitants (0.51%). In the temporal analysis of prevalence, between 2012 and 2017, a reduction of 23% was found in the state rate. The prevalence rate of Paraná for AD is nine times lower than the Brazilian average. Conclusions: Paraná’s prevalence rate for AD is lower than the rates of Brazil and the world, suggesting that AD is underdiagnosed in most municipalities of this state.


Author(s):  
Albert Dayor Piersson ◽  
Wiam Elshami ◽  
Alberta Naa Afia Adjei ◽  
Klenam Dzefi-Tettey ◽  
Philip N. Gorleku

Falls are an important clinical, socioeconomic, and public health problem in the older adult population. Advancing age is a major risk factor for mild cognitive impairment (MCI) and Alzheimer's disease (AD). The preclinical phase of AD, which is regarded as an important window for early therapeutic intervention before the onset of MCI and subsequently AD, can serve as a critical period to reduce or prevent falls among elderly people at risk of AD. In this chapter, first, a discussion is provided on the degrees of fall-related injuries, pain, and severity of falls in elderly people at risk of AD. Secondly, a discussion is provided on the clinical, socioeconomic, and public health implications of falls. Studies that integrated neuroimaging techniques were also reviewed to identify brain biomarkers that can be targeted for the prevention of falls among the elderly. It is anticipated that the outcome of this chapter may have a critical role in the prevention of falls among elderly people at risk or suffering from AD.


2019 ◽  
Vol 67 (2) ◽  
pp. 100-111 ◽  
Author(s):  
Andreas Witt ◽  
Rebecca Brown ◽  
Paul L. Plener ◽  
Elmar Brähler ◽  
Jörg M. Fegert ◽  
...  

Zusammenfassung. Kindesmisshandlung stellt einen bedeutenden Risikofaktor für die Entwicklung dar. Einzelne Formen von Kindesmisshandlung treten häufig nicht isoliert auf, sondern das gemeinsame Auftreten verschiedener Formen von Kindesmisshandlung stellt eher die Regel als die Ausnahme dar. Neben den langfristigen und vielfältigen individuellen Folgen führt Kindesmisshandlung jährlich zu einer hohen gesamtgesellschaftlichen Belastung. Die WHO hat Kindesmisshandlung als großes Public Health Problem identifiziert und die Vereinten Nationen haben den Kampf gegen Kindesmisshandlung zum Ziel in ihrer Agenda für nachhaltige Entwicklung gemacht. In dem vorliegenden Beitrag werden die Häufigkeit sowie das gemeinsame Auftreten unterschiedlicher Formen von Kindesmisshandlung sowie deren Assoziation mit psychischen und somatischen Folgen auf Basis einer bevölkerungsrepräsentativen Stichprobe untersucht und dargestellt. Die Ergebnisse verdeutlichen den Zusammenhang zwischen der Kumulation verschiedener Formen von Misshandlung und negativen Folgen für die Betroffenen. So ist das Risiko für negative Konsequenzen beim Erleben von vier oder mehr Formen von Misshandlung um das bis zu 10-fache erhöht. Viel zu selten werden die kumulativen Effekte von mehreren Belastungen berücksichtigt. Gerade weil die Wirkweisen über die Misshandlung, die Gesundheit beeinflusst, zunehmend gut untersucht sind, muss dieses Wissen im Gesundheitswesen stärker bei der Konzeption von Präventions- und Interventionsmaßnahmen berücksichtigt werden.


Author(s):  
I.E. Levchenko ◽  
◽  
A.Y. Kuznetsov ◽  
E.G. Korniltseva ◽  
◽  
...  

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