Onion extract (Allium cepa L.) up-regulates paraoxonase 1 activity with concomitant protection against LDL oxidation in male wistar strain rats subjected to mercuric chloride induced oxidative stress

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
N Jaiswal ◽  
SI Rizvi
Keyword(s):  
Oxidative Stress ◽  
Allium Cepa ◽  
Mercuric Chloride ◽  
Paraoxonase 1 ◽  
Ldl Oxidation ◽  
Onion Extract ◽  
Wistar Strain ◽  
Allium Cepa L

Amelioration of oxidative stress by dietary fenugreek (Trigonella foenum-graecum L.) seeds is potentiated by onion (Allium cepa L.) in streptozotocin-induced diabetic rats

2017 ◽  
Vol 42 (8) ◽  
pp. 816-828 ◽  
Author(s):  
Seetur R. Pradeep ◽  
Krishnapura Srinivasan
Keyword(s):  
Oxidative Stress ◽  
Beneficial Effect ◽  
Allium Cepa ◽  
Diabetic Rats ◽  
Dietary Interventions ◽  
Fenugreek Seeds ◽  
Soluble Fibre ◽  
Trigonella Foenum Graecum ◽  
Allium Cepa L ◽  
Trigonella Foenum Graecum L

Oxidative stress has a crucial role in the progression of diabetes and its complications. Soluble fibre-rich fenugreek seeds (Trigonella foenum-graecum L.) are understood to have a beneficial effect in the management of diabetes. Previously, we have shown that the amelioration of diabetic hyperglycemia and related metabolic abnormalities was potentiated by onion (Allium cepa L.) in experimental rats. The present study evaluated the additive beneficial effect of dietary fenugreek seeds (10%) and onion (3%) on oxidative stress in diabetic rats. These dietary interventions lowered oxidative stress, the combination producing a higher beneficial effect (p < 0.05), although not additive. Dietary fenugreek, onion, or fenugreek+onion countered hypercholesterolemia (p < 0.05), especially from low-density lipoprotein−associated fraction by 43%, 35%, and 54%, respectively. Elevated concentrations of cholesterol and triglycerides in the liver and heart under diabetic conditions were significantly counteracted by these dietary interventions, with the additive combination resulting in greater effect. These findings were also corroborated by restoration of histopathological abnormalities of heart and liver tissues along with lowered heart and liver weights. It is inferred that an alleviation of oxidative stress contributes further to the antidiabetic influence and this nutraceutical potential of fenugreek seeds and onion was higher when consumed together.

A Comparison of Cytotoxic and Genotoxic Damages Induced by 254 Nm and 365 Nm Radiation: Allium Cepa L. Model

2021 ◽  
Author(s):  
Kültiğin ÇAVUŞOĞLU ◽  
Tuğçe Kalefetoğlu Macar ◽  
Oksal MACAR ◽  
Dilek ÇAVUŞOĞLU ◽  
Emine YALÇIN
Keyword(s):  
Oxidative Stress ◽  
Allium Cepa ◽  
Germination Percentage ◽  
The Other ◽  
Uv Exposure ◽  
Control Group ◽  
Total Weight Gain ◽  
Allium Cepa L ◽  
Living Organisms ◽  
Uv C

Abstract Living organisms are increasingly exposed to ultraviolet (UV) rays of solar radiation, both due to the thinning of the ozone layer and the widespread uses in sterilization processes. The present study was conducted with the purpose of evaluating the damages of UV-A and UV-C radiations in Allium cepa L. roots. Three groups were formed from Allium bulbs, one of which was the control group. One of the other groups was exposed to 254 nm (UV-C) and the other to 365 nm (UV-A) UV. Growth retardation effect of UV was investigated with respect to germination percentage, total weight gain and root elongation, while genotoxicity arisen from UV exposure analyzed using mitotic index (MI) and chromosomal aberrations (CAs) including micronucleus (MN) frequency. Oxidative stress due to UV application was investigated based on the accumulation of malondialdehyde (MDA) and the total activities of superoxide dismutase (SOD) and catalase (CAT) enzymes. Also, meristematic integrity of the UV treated roots was controlled. UV treatments caused significant changes in all parameters compared to the control, but all effects were much more prominent in 254 nm UV-exposed group. This study clearly revealed that UV exposure triggered growth inhibition, genotoxicity, oxidative stress and meristematic cell damages in A. cepa roots depending on the wavelength.

Aluminium induced oxidative stress and DNA damage in root cells of Allium cepa L.

2008 ◽  
Vol 70 (2) ◽  
pp. 300-310 ◽  
Author(s):  
V. Mohan Murali Achary ◽  
Suprava Jena ◽  
Kamal K. Panda ◽  
Brahma B. Panda
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Allium Cepa ◽  
Root Cells ◽  
Allium Cepa L

scholarly journals KEBERHASILAN PERTUMBUHAN STEK JAMBU MADU (Syzygium equaeum) DENGAN PEMBERIAN ZAT PENGATUR TUMBUH KIMIAWI DAN ZAT PENGATUR TUMBUH ALAMI BAWANG MERAH (Allium cepa L)

2019 ◽  
Vol 6 (1) ◽  
pp. 45
Author(s):  
Syariani BR Tambunan ◽  
Nico Syahputra Sebayang ◽  
Wazhi Aminoto Pratama
Keyword(s):  
Allium Cepa ◽  
Growth Regulators ◽  
Growth Regulator ◽  
Leaf Growth ◽  
Block Design ◽  
Natural Growth ◽  
Onion Extract ◽  
Randomized Block Design ◽  
Allium Cepa L

The purpose of this research is to determine the growth of guava cuttings (Syzygium equaeum) by administering a chemical and natural growth regulator from onion extract (Allium cepa L). This study uses Factorial Randomized Block Design (RBD) consisting of 2 treatment factors and 3 replications. The first treatment is the utilization of chemical growth regulators, which consist of C0: no chemical growth regulator, C1: 20 ml chemical growth regulator / 1 liter of water) / cuttings; C2: 20 ml chemical growth regulator / 2 liters of water) / cuttings. The second treatment is the application of natural growth regulators onion extract, which consist of A0: no onion extract, A1: 20 ml onion extract /1 liter of water / cuttings, A2: 30 ml onion extract / 2 liters of water) / cuttings. The highest growth results of cuttings are in C0A1, C0A2 and C2A2, because of auxin and gibberellin hormone in C0A1 and C0A2 where the auxin lengthen the stem and roots, and the gibberellins support the leaf growth, and elongation of shoots and roots.

Evaluation of Antyhipercholesterolemic Effect of Allium cepa L. var cepa in Atherogenic Induced Rats

2021 ◽  
Vol 4 (1) ◽  
pp. 26-32
Author(s):  
Nurahmi Lumban Gaol ◽  
Yuandani ◽  
Panal Sitorus
Keyword(s):  
Allium Cepa ◽  
Atherogenic Diet ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Onion Extract ◽  
Atorvastatin Group ◽  
White Rats ◽  
Group I ◽  
Allium Cepa L

Fermented onion is a type of onion that produced by heating onion bulbs at high temperature for 15 days by fermenter machine. This research is expected to produce new alternatives therapy for reducing cholesterol from onions especially Allium cepa L. var cepa. In this experimental laboratory used 25 male white rats that divided into five groups, group I: negatif control, group II: positif control (Atorvastatin), group III: 100 mg/Kg body weight (bw) of fermented onion extact, group IV: 200 mg/Kg bw of fermented onion extract and group V: 300 mg/Kg bw of fermented onion extract. The Rats was feeding by an atherogenic diet to makes them hypercholesterolemia before treatment for 7th days, 14th days and 21st days. All of data were analyzed by ANOVA method (significant 0,05). The result concludes that of all the doses tested, fermented onion extract of Allium cepa L. var cepa with a dose of 200 mg/Kg bw has the highest effect in decreasing total cholesterol levels of hypercholesterolemia rats (Rattus novergicus).

Antioxidant activity and PC12 cell protective effect of onion flesh and peel(Allium cepa L.) fraction on oxidative stress

2015 ◽  
Vol 49 (2) ◽  
pp. 83-95 ◽  
Author(s):  
Seon-Kyeong Park ◽  
◽  
Dong-Eun Jin ◽  
Chang-Hyeon Park ◽  
Tae-Wan Seung ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Protective Effect ◽  
Allium Cepa ◽  
Pc12 Cell ◽  
Allium Cepa L
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