DeKalb County: A Large Utility Gaining Efficiencies to Accurately Rehab Assets in a Timely Fashion

2020 ◽  
Author(s):  
Darren Eastall ◽  
Gerardo Boquin ◽  
Burhan Shaikh
Keyword(s):  
Genes ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 342
Author(s):  
Lihi Gershon ◽  
Martin Kupiec

Acetylation on lysine 56 of histone H3 of the yeast Saccharomyces cerevisiae has been implicated in many cellular processes that affect genome stability. Despite being the object of much research, the complete scope of the roles played by K56 acetylation is not fully understood even today. The acetylation is put in place at the S-phase of the cell cycle, in order to flag newly synthesized histones that are incorporated during DNA replication. The signal is removed by two redundant deacetylases, Hst3 and Hst4, at the entry to G2/M phase. Its crucial location, at the entry and exit points of the DNA into and out of the nucleosome, makes this a central modification, and dictates that if acetylation and deacetylation are not well concerted and executed in a timely fashion, severe genomic instability arises. In this review, we explore the wealth of information available on the many roles played by H3K56 acetylation and the deacetylases Hst3 and Hst4 in DNA replication and repair.


2017 ◽  
Vol 33 (10) ◽  
Author(s):  
Mário Scheffer ◽  
Saurabh Saluja ◽  
Nivaldo Alonso

The current article examines surgical care as a public health issue and a challenge for health systems organization. When surgery fails to take place in timely fashion, treatable clinical conditions can evolve to disability and death. The Lancet Commission on Global Surgery defined indicators for monitoring sustainable universal access to surgical care. Applied to Brazil, the global indicators are satisfactory, but the supply of surgeries in the country is marked by regional and socioeconomic inequalities, as well as between the public and private healthcare sectors.


2017 ◽  
Vol 181 (11) ◽  
pp. 292-292 ◽  
Author(s):  
Jessica Walsh ◽  
Aaron Percival ◽  
Brian Tapscott ◽  
Patricia V Turner

Appropriate and timely on-farm euthanasia is the responsibility of the producer, working together with their herd veterinarian. Unfortunately, validated methods for euthanasia of commercial meat rabbits are lacking and there are few educational materials available for producer training. Because euthanasia must be performed in a timely fashion to minimise suffering, it is critical to ensure that methods used are aesthetic, humane and effective. We surveyed Canadian meat rabbit producers for current on-farm euthanasia practices as well as attitudes towards the methods they employed and thoughts on novel euthanasia techniques. Surveys were distributed with a response rate of 26 per cent (n=26). Blunt force trauma was the most common euthanasia method used (54 per cent), followed by assisted manual cervical dislocation (31 per cent). Half of producers admitted to not having a euthanasia method in place for all age groups of rabbits, instead electing to let sick and injured rabbits die on their own. While some producers reported feeling highly skilled and satisfied with their current euthanasia method, 58 per cent reported concerns with their current method and 42 per cent desired alternative methods to be developed. Responses to additional questions on training and awareness of euthanasia resources indicated that veterinarians are not part of on-farm euthanasia planning for meat rabbits.


Author(s):  
Linda V. Green

For many years, average bed occupancy level has been the primary measure that has guided hospital bed capacity decisions at both policy and managerial levels. Even now, the common wisdom that there is an excess of beds nationally has been based on a federal target of 85% occupancy that was developed about 25 years ago. This paper examines data from New York state and uses queueing analysis to estimate bed unavailability in intensive care units (ICUs) and obstetrics units. Using various patient delay standards, units that appear to have insufficient capacity are identified. The results indicate that as many as 40% of all obstetrics units and 90% of ICUs have insufficient capacity to provide an appropriate bed when needed. This contrasts sharply with what would be deduced using standard average occupancy targets. Furthermore, given the model's assumptions, these estimates are likely to be conservative. These findings illustrate that if service quality is deemed important, hospitals need to plan capacity based on standards that reflect the ability to place patients in appropriate beds in a timely fashion rather than on target occupancy levels. Doing so will require the collection and analysis of operational data—such as demands for and use of beds, and patient delays—which generally are not available.


2021 ◽  
pp. 1-25
Author(s):  
Anne Kallies

Abstract The law and regulation of the energy sector in Australia is subject to overlapping responsibilities of both federal and state governments. Crucially for energy transition efforts, neither energy, environment nor climate is mentioned in the Australian Constitution. Australia has a tradition of creative cooperative federalism solutions for responding to problems of national importance. In the energy sector this has resulted in an intricate national framework for energy markets, which relies on mirror legislation passed by participating states, with oversight by state and federal executive governments. Independently of these frameworks, both federal and state governments have passed climate change legislation, which crucially includes renewable energy support mechanisms. At a time when a rapid transition to a decarbonized energy system is essential, legal frameworks struggle to respond in a timely fashion. The political discourse around energy has become increasingly toxic – reflecting a dysfunctional state–federal relationship in energy and climate law. Australia needs to consider whether its cooperative federalism solutions are sufficient to support the energy transition and how climate law at the state and federal levels interacts with energy market legal frameworks.


2017 ◽  
Vol 4 (8) ◽  
pp. 170660 ◽  
Author(s):  
Sam Darvishi ◽  
Michael C. Ridding ◽  
Brenton Hordacre ◽  
Derek Abbott ◽  
Mathias Baumert

Restorative brain–computer interfaces (BCIs) have been proposed to enhance stroke rehabilitation. Restorative BCIs are able to close the sensorimotor loop by rewarding motor imagery (MI) with sensory feedback. Despite the promising results from early studies, reaching clinically significant outcomes in a timely fashion is yet to be achieved. This lack of efficacy may be due to suboptimal feedback provision. To the best of our knowledge, the optimal feedback update interval (FUI) during MI remains unexplored. There is evidence that sensory feedback disinhibits the motor cortex. Thus, in this study, we explore how shorter than usual FUIs affect behavioural and neurophysiological measures following BCI training for stroke patients using a single-case proof-of-principle study design. The action research arm test was used as the primary behavioural measure and showed a clinically significant increase (36%) over the course of training. The neurophysiological measures including motor evoked potentials and maximum voluntary contraction showed distinctive changes in early and late phases of BCI training. Thus, this preliminary study may pave the way for running larger studies to further investigate the effect of FUI magnitude on the efficacy of restorative BCIs. It may also elucidate the role of early and late phases of motor learning along the course of BCI training.


2016 ◽  
Vol 40 (1) ◽  
pp. 2-20 ◽  
Author(s):  
Steven Tam ◽  
David E Gray

Purpose – The purpose of this study is to relate the practice of organisational learning in small- and medium-sized enterprises (SMEs) to the organisational life cycle (OLC), contextualising the differential aspects of an integrated relationship between them. Design/methodology/approach – It is a mixed-method study with two consecutive phases. In Phase I, 30 Hong Kong SMEs identified through theoretical sampling were classified into three life-cycle stages – inception, high growth and maturity. In Phase II, their employees’ learning practices (grouped by learning levels) were statistically compared using the analysis of variance and then followed up for confirmation with qualitative semi-structured interviews. Findings – This study uniquely suggests the nature of a relationship between SME organisational learning and the OLC. Empirical results show that three of the four learning levels (individual, group, organisational and inter-organisational) practised in SMEs are varied in importance between life-cycle stages. Research limitations/implications – Comparative studies are encouraged in other parts of the world to strengthen the findings – with either SMEs or large organisations. Practical implications – The study informs SME owner/managers about what is important for employee learning at different business stages so that appropriate learning strategies or human resource development policies can be formulated in a timely fashion to promote competitiveness. Originality/value – It is among the first studies to connect SME learning with organisational growth. The relationships found serve as a sound foundation for further empirical investigations.


2020 ◽  
Vol 48 (2020) ◽  
pp. 1-3
Author(s):  
William R. Mabee ◽  
Brandy S. Bergthold ◽  
Carl K. Wakefield ◽  
Matthew D. Combes

Abstract First records of occurrence of the midge genus Kloosia Kruseman in Missouri are reported based upon aquatic macroinvertebrate community samples collected during April 2012 and October 2015 from reaches of Grindstone Creek in Dekalb County and South Blackbird Creek in Schuyler County in the Central Dissected Till Plains. Select physical and water quality characteristics from the reaches are also provided.


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