scholarly journals Major structural proteins of type B, type C, and type D oncoviruses share interspecies antigenic determinants.

1980 ◽  
Vol 77 (1) ◽  
pp. 72-76 ◽  
Author(s):  
M. Barbacid ◽  
L. K. Long ◽  
S. A. Aaronson
2017 ◽  
Vol 17 (3) ◽  
pp. 39-56 ◽  
Author(s):  
Sérgio Roberto Andrade Dantas ◽  
Fulvio Vittorino ◽  
Kai Loh

Abstract Contact of facades with degradation agents and direct incidence of ultraviolet radiation on external coatings make them more opaque over time, affecting their colour and reflectance characteristics. This study evaluated the effect of adding different TiO2 contents to mortars applied in concrete substrates in order to verify the reflectance maintenance on surfaces after exposure over time. Mortar with different concentrations of TiO2 (1%, 5%, 10%) were produced in relation to the total dry premix, added as a powder and compared to unpainted mortar without TiO2 (type "A") and painted mortar without TiO2 (type "B"), both used as a reference for colour and reflectance. Exposed over 16 months to climate conditions in São Paulo, regarding the maintenance of reflectance and solar radiation, the results showed that type "B" (0%TiO2) painted mortar presented the best performance. Type "C" (1%TiO2) and type "D" (5%TiO2) unpainted mortar remained more stable. Type "A" (0%TiO2) and type "E" (10%TiO2) unpainted mortar showed greater differences according to the Just Noticeable Difference (JND) range caused by dirt pick up.


2019 ◽  
Vol 130 (5) ◽  
pp. 1468-1477 ◽  
Author(s):  
David Hasan ◽  
Mario Zanaty ◽  
Robert M. Starke ◽  
Elias Atallah ◽  
Nohra Chalouhi ◽  
...  

OBJECTIVEThe overall risk of ischemic stroke from a chronically occluded internal carotid artery (COICA) is around 5%–7% per year despite receiving the best available medical therapy. Here, authors propose a radiographic classification of COICA that can be used as a guide to determine the technical success and safety of endovascular recanalization for symptomatic COICA and to assess the changes in systemic blood pressure following successful revascularization.METHODSThe radiographic images of 100 consecutive subjects with COICA were analyzed. A new classification of COICA was proposed based on the morphology, location of occlusion, and presence or absence of reconstitution of the distal ICA. The classification was used to predict successful revascularization in 32 symptomatic COICAs in 31 patients, five of whom were female (5/31 [16.13%]). Patients were included in the study if they had a COICA with ischemic symptoms refractory to medical therapy. Carotid artery occlusion was defined as 100% cross-sectional occlusion of the vessel lumen as documented on CTA or MRA and confirmed by digital subtraction angiography.RESULTSFour types (A–D) of radiographic COICA were identified. Types A and B were more amenable to safe revascularization than types C and D. Recanalization was successful at a rate of 68.75% (22/32 COICAs; type A: 8/8; type B: 8/8; type C: 4/8; type D: 2/8). The perioperative complication rate was 18.75% (6/32; type A: 0/8 [0%]; type B: 1/8 [12.50%]; type C: 3/8 [37.50%], type D: 2/8 [25.00%]). None of these complications led to permanent morbidity or death. Twenty (64.52%) of 31 subjects had improvement in their symptoms at the 2–6 months’ follow-up. A statistically significant decrease in systolic blood pressure (SBP) was noted in 17/21 (80.95%) patients who had successful revascularization, which persisted on follow-up (p = 0.0001). The remaining 10 subjects in whom revascularization failed had no significant changes in SBP (p = 0.73).CONCLUSIONSThe pilot study suggested that our proposed classification of COICA may be useful as an adjunctive guide to determine the technical feasibility and safety of revascularization for symptomatic COICA using endovascular techniques. Additionally, successful revascularization may lead to a significant decrease in SBP postprocedure. A Phase 2b trial in larger cohorts to assess the efficacy of endovascular revascularization using our COICA classification is warranted.


Author(s):  
Yutaro Koike ◽  
Aritoshi Hattori ◽  
Takeshi Matsunaga ◽  
Kazuya Takamochi ◽  
Shiaki Oh ◽  
...  

AbstractOBJECTIVESSegmentectomy has become an increasingly popular surgical procedure for small-sized lung lesions. Left upper trisegmentectomy (LUTS) is one of the most common segmentectomies performed because of its relative ease and simplicity; however, limited information is currently available on the specific postoperative complications associated with this procedure.METHODSAmong 2060 surgically resected cases in our institute between 2009 and 2016, 129 (6.2%) underwent LUTS. Postoperative chest X-rays and/or thoracic computed tomography (CT) scans were retrospectively assessed for all cases to assess postsurgical residual lung complications following LUTS. We categorized cases into 4 groups: type A (atelectasis of the lingular segment), type B (lung torsion of the lingular segment), type C (necrosis of the ‘isolated segment’) and type D (haematoma along stapling lines).RESULTSPostsurgical lung complications following LUTS were observed in 17 (13.1%) patients (type A: n = 7, type B: n = 1, type C: n = 4 and type D: n = 5). Three patients (2.3%) required surgical intervention because of type B (n = 1) and type C (n = 2), namely, decreased permeability and remaining ground glass opacities in the residual lung, showing an exacerbated systemic inflammatory response. In contrast, type A and D cases were successfully observed by chest CT without any surgical intervention, and patients recovered within a few months of surgery.CONCLUSIONSWe identified several postoperative residual lung complications following LUTS. Lung torsion or necrosis of the residual segment may require intensive care, including reoperation. Potentially serious complications always need to be ruled out after LUTS when radiological consolidation is detected postoperatively.


2015 ◽  
Vol 20 (2) ◽  
pp. 90-101 ◽  
Author(s):  
Sung-Wook Jeong ◽  
Lee-Suk Kim

Objectives: The aims of this study were to introduce a new classification of cochleovestibular malformation (CVM) and to investigate how well this classification can predict speech perception ability after cochlear implantation in children with CVM. Methods: Fifty-nine children with CVM who had used a cochlear implant for more than 3 years were included. CVM was classified into 4 subtypes based on the morphology of the cochlea and the modiolus on temporal bone computed tomography (TBCT): normal cochlea and normal modiolus (type A, n = 16), malformed cochlea and partial modiolus (type B, n = 31), malformed cochlea and no modiolus (type C, n = 6), and no cochlea and no modiolus (type D, n = 6). Speech perception test scores were compared between the subtypes of CVM using analysis of covariance with post hoc Bonferroni test. Univariate and multivariate regression analyses were used to identify the significant predictors of the speech perception test scores. Results: The speech perception test scores after implantation were significantly better in children with CVM type A or type B than in children with CVM type C or type D. The test scores did not differ significantly between the implanted children with CVM type A or type B and those without CVM. In univariate regression analysis, the type of CVM was a significant predictor of the speech perception test scores in implanted children with CVM. Multivariate regression analysis revealed that the age at cochlear implantation, cochlear nerve size and preimplantation speech perception test scores were significant predictors of the postimplantation speech perception test scores. The chance of cochlear nerve deficiency increased progressively from CVM type A to type D. Conclusion: The new classification of CVM based on the morphology of the cochlea and the modiolus is simple and easy to use, and correlated well with postimplantation speech perception ability and cochlear nerve status. This simple classification of CVM using TBCT with cochlear nerve assessment by magnetic resonance imaging is helpful in the preoperative evaluation of children with CVM.


2011 ◽  
Vol 69 (suppl_2) ◽  
pp. ons121-ons140 ◽  
Author(s):  
Yoichi Nonaka ◽  
Peter M. Grossi ◽  
Ketan R. Bulsara ◽  
Raymond M. Taniguchi ◽  
Allan H. Friedman ◽  
...  

Abstract BACKGROUND Schwannomas originating from the hypoglossal nerve are extremely rare. Microsurgical resection with the goal for cure has traditionally been associated with a high risk of postoperative deficits. OBJECTIVE To summarize our clinical experience using tailored cranial base approaches for these formidable lesions. METHODS The clinical records of 13 patients were retrospectively reviewed. In addition, all reported patients in the literature were reviewed. The extreme lateral infrajugular transcondylar-transtubercular exposure approach was used in all of our patients. Based on our experience and literature analysis, we propose the following modified grading scale to facilitate surgical planning: type A, intradural tumors; type B, dumbbell-shaped tumors; type C, extracranial tumors; and type D, peripheral tumors. RESULTS All 13 patients underwent total, near-total, or subtotal tumor resection. Eight patients were men, 5 were women (mean age, 41.7 years). Sural nerve graft reconstruction for the hypoglossal nerve was performed in 4 patients. Three of the 4 patients in whom nerve reconstruction was performed regained satisfactory movement of their tongue. In the review of the literature, the mean patient age was 45.8 years. Patients presented with tongue atrophy (91.6%), headache (60.9%), and dysphagia (31.8%). The tumors were categorized as type A in 31.7% of these patients, type B in 38.6%, type C in 6.2%, and type D in 23.4%. CONCLUSION The extreme lateral infrajugular transcondylar-transtubercular exposure approach, which is a modification of the extreme lateral suboccipital approach, provides sufficient exposure for most intracranial dumbbell-shaped hypoglossal schwannomas. Hypoglossal nerve reconstruction using a sural nerve graft improves tongue atrophy and movement for patients with resected nerves.


Author(s):  
Anju Antony ◽  
Pramod Kumar

<p class="abstract"><strong>Background:</strong> Pigmentary demarcation lines (PDL) correspond to a border of abrupt transition between the more deeply pigmented skin of the outer surfaces and the lighter inner surfaces. On the basis of their location they have been classified into eight types, type A to type H. The present study is an attempt to obtain a better understanding of the clinical types of pigmentary demarcation lines in Indians, and to report any previously undescribed patterns of pigmentation.</p><p class="abstract"><strong>Methods:</strong> Patients attending the Outpatient Department for various complaints were examined for the presence of pigmentary demarcation lines, and those with pigmentary demarcation lines were analysed further.<strong></strong></p><p class="abstract"><strong>Results:</strong> 50 subjects of Fitzpatrick skin types 4 and 5, with pigmentary demarcation lines were examined in detail. The various types of pigmentary demarcation lines seen were Type A (38%), Type B (14%), Type C (24%), Type F (22%), Type G (4%), Type H (4%). All types were more common in females with the exception of Type C, which was observed only in males. Type D and Type E PDL were not observed in any of the subjects screened.</p><p class="abstract"><strong>Conclusions:</strong> The most common type of PDL observed in our study was Type A PDL, followed by Type C PDL. The youngest subject was 2 years old, the oldest was aged 75.The majority were seen in adults; Type A and Type C PDL were the common types seen in children. A family history of PDL was present in 5 (10%) and all were females. A hitherto undescribed pigmentary demarcation line is also described along with this study.</p>


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Benqiang Tang ◽  
Songjie Xu ◽  
Xueming Chen ◽  
Libin Cui ◽  
Yanhui Wang ◽  
...  

Abstract Background The impact of intravertebral cleft (IVC) on cement leakage in percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCFs) has been discussed. However, the results were conflicting, as the study population and cement leakage classification were heterogeneous. The aim of the study was to evaluate the impact of IVC on the incidence of leakage through vein, leakage through cortex as well as general leakage in PVP for OVCFs. Methods All patients with OVCFs who underwent PVP between January 2016 and June 2019 at our institution were retrospectively reviewed. Patients were eligible for this case-control study if they were diagnosed as single level fracture in spine. After inclusive and exclusive criteria were met, a total of 139 patients with IVC were enrolled as the study group. Non-IVC controls were matched in a 1:1 ratio in age (within 3 years), sex and fracture severity with patients in study group. Cement leakage were classified into four types [type B (through basivertebral vein), type S (through segmental vein), type-C (through a cortical defect), and type D (intradiscal leakage)], furtherly into two types [venous type (type-B or/and type S) and cortical type (type-C or/and type-D)]. A general leakage rate and a specific leakage rate per each type were compared between both groups. Results Each group included 139 patients. Groups were homogenous for age, sex, fracture severity, fracture location, fracture type, cement volume, puncture approach and property of cement. Compared with control group, IVC group had a significantly lower rate of type-B (20.9% vs. 31.7%, P = 0.041), type-S (24.5% vs. 52.5%, P = 0.000), and venous type leakage (37.4% vs. 67.6%, P = 0.000), a significantly higher rate of type-C (25.9% vs. 12.2%, P = 0.004), type-D (16.5% vs. 6.5%, P = 0.009), and cortical type leakage (40.3% vs. 16.5%, P = 0.000), no significant difference on the rate of general leakage (67.6% vs. 76.3%, P = 0.109). Conclusion IVC decreased the risk of cement leakage through vein and increased the risk of cement leakage through cortex. However, it had no significant effect on the occurrence of general leakage.


Author(s):  
Toshikazu Ohkubo ◽  
Duan Li ◽  
Daisuke Yakushiji ◽  
Seiji Kanazawa ◽  
Yukiharu Nomoto

AbstractIn this study, the improvement in the decomposition of volatile organic compounds (VOCs) was investigated by combining discharge plasma with catalyst. DC streamer corona plasma reactors combined with a catalyst were developed. The basic configuration of the reactors is a multineedle-to-plane mesh electrode system. By changing the position of catalyst against the plasma region, several reactors were developed and compared with each other. As a catalyst, a honeycomb catalyst (Mn type) was tested. A catalyst layer was located between the needles and plane mesh electrodes (type A reactor), or the catalyst layer was placed just behind the mesh electrode (type B reactor). In other reactors, the catalyst layer was followed by the needles-to- plane mesh electrode system (type C reactor) or the catalyst layer was removed (type D reactor). The needles- to-plane mesh electrode system produced the stable streamer corona discharge. The streamers covered the surface of the catalyst layer in the type A and type B reactors. However, the characteristics of the streamer were different for the type A and type B reactors. Toluene (C


Early China ◽  
1986 ◽  
Vol 9 (S1) ◽  
pp. 5-7
Author(s):  
Gao Zhixi

ABSTRACTTwenty-two bronze nao-bells dating to the late Shang and early Western Zhou periods have been unearthed from the five southern provinces of Hunan, Jiangsi, Zhejiang, Jiangsu, and Fujian. Of these, sixteen were from Hunan, three from Zhejiang, and one each from the remaining three provinces. These bells can be classified into four categories: type A has an animal mask decoration (eleven examples); type B has a cloud pattern (three examples); type C has nipples (only one example); type D has stalks (mei, seven examples).The nao is a bell that can produce two tones. It can be used in sacrificial offerings as well as war. Because most of these bells have been discovered at the top, mid-section, or foot of mountains or on the banks of a river, we surmise that they may have been used in contemporary sacrifices to the mountains and streams, wind and rain, and stars, etc. Based on the periodization of the style of their shape and decoration we conclude that type A may be as early as late Shang, type B can be assigned to the end of the Shang, type C is from the beginning of the Zhou and type D belongs to the early Western Zhou. They developed from type A to B to C to D and then to the yong-bell. The characteristics of southern nao bells are: they are large, thick and heavy; most have whorls on the circular handle; many animal masks and cloud and lightning patterns are formed from thick lines among the decoration; the entire body is usually covered with decoration; most appear singly, and they were set up on their stands with the mouth facing up. In contrast, northern nao-bells are very small, they have no whorls on the handle, their decoration is simple, and they are unearthed in groups of several together.


Toxins ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 650
Author(s):  
Katia Forti ◽  
Laura Ferroni ◽  
Martina Pellegrini ◽  
Deborah Cruciani ◽  
Antonio De Giuseppe ◽  
...  

Clostridium (C.) perfringens is the causative agent of several diseases and enteric infections in animals and humans. The pathogenicity of the bacterium is largely mediated by the production of a wide range of toxins. Individual C. perfringens strains produce only subsets of this toxin repertoire, which permits the classification in seven toxinotypes (A–G). In addition, a variety of minor toxins further characterizes the single strains. The aim of this work was to evaluate, using Polymerase Chain Reaction (PCR) assays, the diversity of 632 C. perfringens strains isolated in Italy over 15 years. The genotyped strains were analyzed to determine the presence of major and minor toxins (cpe, consensus, and atypical cpb2), their geographical origins, and the source of isolation (animal species or food). Our study shows that toxinotype A had the greatest representation (93%) and correlated mainly with consensus cpb2 in a variety of animal species, as well as with atypical cpb2 in the five food samples. Type D, associated with cpe and atypical cpb2 minor toxins, was identified in 3% of the cases, and type F was identified in 2.5%. Seven type C isolates (1.1%) were detected in cattle, whereas the only type B atypical cpb2 isolated in Italy was detected in a goat, and one type E cpe+atypical cpb2 was detected in a sheep. Type G was not detected.


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