scholarly journals Phylloquinone (vitamin K1) intakes and serum undercarboxylated osteocalcin levels in Irish postmenopausal women

2006 ◽  
Vol 95 (5) ◽  
pp. 982-988 ◽  
Author(s):  
Aoife Collins ◽  
Kevin D. Cashman ◽  
Máiréad Kiely
Keyword(s):  
Postmenopausal Women ◽  
Daily Intake ◽  
Food Composition ◽  
Primary Sources ◽  
Food Sources ◽  
Undercarboxylated Osteocalcin ◽  
Mineral Density ◽  
Total Contribution ◽  
Dietary History ◽  
The Uk

Low phylloquinone (vitamin K1) intakes have been associated with low bone mineral density in older adults. Phylloquinone intakes and serum undercarboxylated osteocalcin (ucOC) levels were assessed in ninety-seven apparently healthy, free-living Irish women aged 50–75 years. Phylloquinone intakes were estimated using a detailed dietary history, which measured habitual food intakes from a typical 14 d period, and recently published food composition data for phylloquinone. Fasting serum ucOC was measured using an enzyme immunoassay. The median daily intake of phylloquinone in the group from all sources was 108·8 mg and from food sources only was 106·6 mg, indicating that approximately 99% of the phylloquinone came from food. Vegetables and vegetable dishes contributed 67% of the total phylloquinone intake, but further analysis showed that broccoli, cabbage and lettuce were the primary sources, making a total contribution of 44 %. Twenty per cent of the women had a phylloquinone intake below the UK recommendation of 1μg/kg body weight per day and 34% failed to meet the US Adequate Intake value of 90mg/day. Mean serum ucOC levels in the women were 6·2 (SD 1·7) ng/ml and were predicted by phylloquinone intake (β— 22·20, generated from log-transformed phylloquinone intake data; P=4 0·04). On the basis of comparisons with both UK recommendations and US A equate Intakes for phylloquinone, the habitual intakes of phylloquinone in a high proportion of Irish postmenopausal women may not be adequate.

A Preliminary Assessment of Vitamin K1 Intakes and Serum Undercarboxylated Osteocalcin Levels in 11–13 Year Old Irish Girls

2006 ◽  
Vol 76 (6) ◽  
pp. 385-390 ◽  
Author(s):  
Collins ◽  
Cashman ◽  
Kiely
Keyword(s):  
Vitamin K ◽  
Large Scale ◽  
Bone Growth ◽  
Food Composition ◽  
Undercarboxylated Osteocalcin ◽  
Mineral Density ◽  
Serum Samples ◽  
Old Irish ◽  
Dietary History ◽  
Food Composition Data

Low vitamin K1 intakes have been associated with low bone mineral density in women and reduced bone turnover in girls. No European data exist on the relationship between vitamin K1 and serum undercarboxylated osteocalcin (ucOC), an indicator of K1 status in adolescents. The aim of the current study was to assess intakes of vitamin K1 in relation to serum ucOC status in Irish girls. A detailed dietary history method, which measured habitual intakes from a typical 14-day period, was used to estimate vitamin K1 intakes in 18 girls aged 11–13 years. Recently compiled and validated food composition data for vitamin K1 were used to determine vitamin K1 intakes. An enzyme immunoassay was used to measure ucOC in fasting serum samples. The mean (± SD) intake of vitamin K1 in the girls was 72.4 μg/day (SD 34.4). Vegetables (particularly broccoli, composite dishes, and lettuce) contributed 53% of total vitamin K1 intakes. Thirty-Seven percent of the girls failed to meet the current U.S. adequate intake for adolescents of 60 μg/day vitamin K1. Serum ucOC levels were inversely related to body weight-adjusted vitamin K1 intakes, controlling for energy intake (partial correlation r = –0.538; p = 0.026). The data indicate that large-scale studies to examine relationships between vitamin K1 (and green vegetable) intakes and bone growth and development in adolescents are warranted.

scholarly journals FODMAP Intake in Spanish Population: Open Approach for Risk Assessment

2020 ◽  
Vol 17 (16) ◽  
pp. 5882
Author(s):  
Jonatan Miranda ◽  
Maialen Vázquez-Polo ◽  
Gesala Pérez-Junkera ◽  
María del Pilar Fernández-Gil ◽  
María Ángeles Bustamante ◽  
...  
Keyword(s):  
Nutrient Intake ◽  
Adult Population ◽  
Age Groups ◽  
Daily Intake ◽  
Food Samples ◽  
Food Composition ◽  
Food Sources ◽  
Open Approach ◽  
Adolescents And Adults ◽  
Fermentable Carbohydrates

Fermentable oligo-, di- and monosaccharides and polyols’ (FODMAP) were related with intestinal complications. The present study aimed to determine the FODMAP consumption of Spanish children, adolescents and adults, analyzing the real FODMAP risk of foods, and to set an open methodology for the measurement of this intake in other regions as well as nutrient intake assurance. Total fructan analysis was performed analytically in eighty-seven food samples. Daily intake of FODMAPs, fiber and micronutrients was calculated by combining the food composition for selected fermentable carbohydrates with the national food consumption stratified by age in an open software. Spanish child and adolescent total FODMAP consumption was settled as 33.4 ± 92.4 and 27.3 ± 69.0 g/day, respectively. Both intakes were higher than that of the adult population (21.4 ± 56.7 g/day). The most important food sources of lactose, excess of fructose and total fructan, considering their content and dietary intake were different between age groups. The contribution of these foods to dietary calcium and fiber and the consequent risk of deficiency if they are withdrawn was highlighted. We demonstrated the relevance of stratifying the total FODMAP intake by age. An open approach for FODMAP intake quantification and nutrient control was provided.

scholarly journals Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women

2016 ◽  
Vol 175 (6) ◽  
pp. 541-549 ◽  
Author(s):  
Sofie Hertz Rønn ◽  
Torben Harsløf ◽  
Steen Bønløkke Pedersen ◽  
Bente Lomholt Langdahl
Keyword(s):  
Placebo Group ◽  
Trabecular Bone ◽  
Postmenopausal Women ◽  
Bone Structure ◽  
Bone Microarchitecture ◽  
Vitamin K2 ◽  
Undercarboxylated Osteocalcin ◽  
Mineral Density ◽  
Trabecular Thickness ◽  
Age Related

Objective Clinical studies suggest that vitamin K2 protects against bone loss and fractures; however, its effect on bone quality has never been investigated. We investigated the effect of vitamin MK-7 on undercarboxylated osteocalcin (ucOC), and bone mass and quality. Design We conducted a randomised, placebo-controlled, double-blinded clinical trial. Methods We investigated the effect of MK-7 375 µg for 12 months on bone mineral density (BMD) measured by dual X-ray absorptiometry (DXA), bone microarchitecture measured by high-resolution peripheral quantitative computed tomography (HRpQCT) and biochemical bone turnover markers in 148 postmenopausal women with osteopenia. All of them were supplemented with calcium and vitamin D. Results ucOC decreased in the MK-7 group (−65.6 (59.1; 71.0) %) (median (CI)) compared with the placebo group (−6.4 (−13.5; 1.2) %) after 3 months (P < 0.01). HRpQCT after 12 months demonstrated that trabecular number in tibia was unchanged in the MK-7-group (−0.1 ± 1.9%) (mean ± s.d.) and decreased in the placebo group (−3.5 ± 2.2%), trabecular spacing was unchanged in the MK-7 group (+1.2 ± 8.0%) and increased in the placebo group (+4.5 ± 9.7%), and trabecular thickness was unchanged in the MK-7 group (+0.2 ± 1.7%) and increased in the placebo group (+4.0 ± 2.2%) (between-group changes for all: P < 0.05). There were no significant differences between the groups in HRpQCT-derived parameters at the radius or in BMD at any site. Conclusion The changes in bone microarchitecture in the placebo group are consistent with the age-related deterioration of trabecular structure, with a loss of trabeculae and a greater mean thickness of the remaining trabeculae. This suggests that vitamin MK-7 preserves trabecular bone structure at the tibia.

scholarly journals Phylloquinone (vitamin K1) intakes and food sources in 18–64-year-old Irish adults

2004 ◽  
Vol 92 (1) ◽  
pp. 151-158 ◽  
Author(s):  
Paula Duggan ◽  
Kevin D. Cashman ◽  
Albert Flynn ◽  
Caroline Bolton-Smith ◽  
Máiréad Kiely
Keyword(s):  
Vitamin K ◽  
Bone Health ◽  
Smoking Status ◽  
Daily Intake ◽  
Food Composition ◽  
Food Sources ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Food Diary ◽  
The North

AbstractDietary vitamin K1(phylloquinone) levels that are sufficient to maintain normal blood coagulation may be sub-optimal for bone, and habitual low dietary intakes of vitamin K may have an adverse effect on bone health. The objective of the present study was to measure the intake and adequacy of phylloquinone intake and the contribution of foods to phylloquinone intake in a nationally representative sample of Irish adults. The North/South Ireland Food Consumption Survey database was used, which contains data collected using a 7 d food diary in a randomly selected sample of Irish adults aged 18–64 years (n1379; 662 men and 717 women). Phylloquinone intakes were estimated using recently compiled food composition data for phylloquinone. The mean daily intake of phylloquinone from food sources was 79 (sd 44) μg. Intakes were significantly higher (P>0·001) in men than in women at levels of 84 and 75quest;μgsol;d. The main contributors to phylloquinone intakes were vegetables (48%), particularly green vegetables (26%). Potatoes (including chipped and fried potatoes), dairy products and fat spreads contributed 10% each and meat contributed 8%. In men, social class and smoking status influenced phylloquinone intakes. Of the population, 52% had phylloquinone intakes below 1 μg/kg body weight and only 17% of men and 27% of women met the US adequate intakes of 120 and 90 μg/d, respectively. The present study shows that habitual phylloquinone intakes in Irish adults are low, which may have implications for bone health.

scholarly journals Influence of coffee consumption on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history

2014 ◽  
Vol 4 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Amila Kapetanović ◽  
Dijana Avdic
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Daily Intake ◽  
Coffee Consumption ◽  
Estrogen Deficiency ◽  
Control Group ◽  
Mineral Density ◽  
Average Daily Intake ◽  
Menstrual History

Introduction: Complex etiology of osteoporosis include genetic, hormonal, environmental and nutritional factors. The aim of this study was to examine influence of coffee consumption on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history.Methods: This prospective study included 100 postmenopausal women, aged 50-65 years living in Sarajevo area, with estrogen deficiency in their menstrual history. The controlled clinical trials were conducted. Two groups were formed (based on bone mineral density values). The examination group included 50 women who had osteoporosis, while the control group included 50 women without osteoporosis (osteopenia, normal bone mineral density). The lumbar spine and proximal femur bone mineral density was measured by Dual–Energy X–ray Absorptiometry using Hologic QDR-4000 scanner. Coffee drinking habits were assessed for each subject.Results: The average daily intake of coffee in women with estrogen deficiency in menstrual history was at 267.6 ml in the examination group and in the control group 111.6 ml. The difference in the average daily intake of coffee between the two groups was statistically significant (p < 0.001). There was registered significant correlation between intake of coffee and bone mineral density in examination (p < 0.01) and in control group (p < 0.05).Conclusion: This study indicates that coffee consumption is a risk factor for osteoporosis in postmenopausal women, aged 50-65 years living in Sarajevo area, with estrogen deficiency in their menstrual history. It was shown that the effects of coffee on bone mineral density are dose-dependent.

scholarly journals Estimation of dietary flavonoid intake and major food sources of Korean adults

2015 ◽  
Vol 115 (3) ◽  
pp. 480-489 ◽  
Author(s):  
Shinyoung Jun ◽  
Sangah Shin ◽  
Hyojee Joung
Keyword(s):  
Daily Intake ◽  
Epidemiological Studies ◽  
Food Composition ◽  
Food Sources ◽  
Food Groups ◽  
Food Items ◽  
Korean Adults ◽  
Flavonoid Intake ◽  
Composition Table ◽  
Vegetables And Fruits

AbstractEpidemiological studies have suggested that flavonoids exhibit preventive effects on degenerative diseases. However, lack of sufficient data on flavonoid intake has limited evaluating the proposed effects in populations. Therefore, we aimed to estimate the total and individual flavonoid intakes among Korean adults and determine the major dietary sources of these flavonoids. We constructed a flavonoid database of common Korean foods, based on the food list reported in the 24-h recall of the Korea National Health and Nutrition Examination Survey (KNHANES) 2007–2012, using data from the Korea Functional Food Composition Table, US Department of Agriculture flavonoid database, Phenol-Explorer database and other analytical studies. This database, which covers 49 % of food items and 76 % of food intake, was linked with the 24-h recall data of 33 581 subjects aged ≥19 years in the KNHANES 2007–2012. The mean daily intake of total flavonoids in Korean adults was 318·0 mg/d, from proanthocyanidins (22·3 %), flavonols (20·3 %), isoflavones (18·1 %), flavan-3-ols (16·2 %), anthocyanidins (11·6 %), flavanones (11·3 %) and flavones (0·3 %). The major contributing food groups to the flavonoid intake were fruits (54·4 %), vegetables (20·5 %), legumes and legume products (16·2 %) and beverages and alcohols (3·1 %), and the major contributing food items were apples (21·9 %), mandarins (12·5 %), tofu (11·5 %), onions (9·6 %) and grapes (9·0 %). In the regression analysis, the consumption of legumes and legume products, vegetables and fruits predicted total flavonoid intake the most. The findings of this study could facilitate further investigation on the health benefits of flavonoids and provide the basic information for establishing recommended flavonoid intakes for Koreans.

scholarly journals Iron Content of Some Popular Cooked Foods Consumed by the Rural School Children in Sri Lanka

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
D. Ruwani G. Perera ◽  
Dilantha Gunawardana ◽  
Renuka Jayatissa ◽  
A. Buddhika G. Silva
Keyword(s):  
Iron Content ◽  
Daily Intake ◽  
The United States ◽  
Food Composition ◽  
Food Sources ◽  
United States Department ◽  
Sri Lankan ◽  
High Iron Content ◽  
Green Leaves ◽  
Composition Table

Iron is an important micronutrient that can be found in different food sources in varying quantities. Iron deficiency is common in populations consuming cereal-based diets with little or no animal-derived food products. Rice is the staple for Sri Lankans, which may not provide sufficient bioavailable iron. Sri Lankan food composition table does not contain data on iron in home-cooked foods. Aim of the present study was to determine the iron content in commonly consumed home-cooked foods (rice, vegetables, green leaves, pulses, fish, etc.) by children aged 15-16 years. The study was carried out in eight schools at the Divisional Secretariat, Horana. The average iron values of cooked rice, vegetables, green leaves, pulses, and fish were 23.29 ± 14.46, 19.34 ± 9.90, 29.56 ± 13.64, 45.16 ± 22.28, and 46.72 ± 14.53 mg/kg, respectively. A serving of cooked red raw rice (rathu kekulu) provided the highest Estimated Daily Intake (EDI) of iron. The total EDI per serving for all categories was 6.39 ± 1.06 mg, contributing to the recommended daily allowance (RDA) of 42.62% of girls and 58.12% of boys as defined by the United States Department of Agriculture. Meanwhile, based on the Sri Lankan RDA, dietary iron contribution per serving ranges from 16.39% to 17.76% in girls and 16.39% to 21.31% in boys in the 15-16 years age category. Therefore, these home-cooked foods which were prepared using local recipes have high iron content and can replenish a major proportion of recommended quotidian values for iron intake.

scholarly journals Dietary calcium intake and osteoporosis in postmenopausal women living in Sarajevo area

2012 ◽  
Vol 2 (2) ◽  
pp. 118-121
Author(s):  
Amila Kapetanović ◽  
Dijana Avdić
Keyword(s):  
Bone Density ◽  
Postmenopausal Women ◽  
Calcium Intake ◽  
Positive Impact ◽  
Daily Intake ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Control Group ◽  
Mineral Density ◽  
Mineral Bone Density

Introduction: Osteoporosis is a multifactorial polygenetic disease of which the genetic determinants are modulated by hormonal, environmental and nutritional factors. Identifi cation of the risk factors for osteoporosisrelated to nutrition is important in the prevention and treatment of this disease, considering that these factors can be modifi ed. The aim of this study was to examine infl uence of dietary calcium intake on bonemineral density in postmenopausal women who hadn’t a deficit of estrogen in their menstrual history.Methods: A total of 100 postmenopausal women living in Sarajevo area, aged 50-65 years, without estrogen deficiency in menstrual history were included in the study. Mineral bone density was measured at the lumbarspine and proximal femur by Dual–Energy X–ray Absorptiometry using Hologic QDR-4000 scanner. Examination and control group were formed based on mineral bone density values. The women in the examinationgroup had osteoporosis. The women in the control group had osteopenia or normal mineral bone density. Estimates of daily dietary calcium intake were performed based on a Food Frequency Questionnaire.Results: The average daily intake of dietary calcium among women who had osteoporosis was 967.32 mg, and in women who hadn’t osteoporosis 1195.12 mg. The difference between two groups was statistically significant (p<0.001). There was registered signifi cant correlation between intake of dietary calcium and mineral bone density in examination (p<0.01) and in control group (p<0.01).Conclusion: The results of this study have shown that adequate daily intake of dietary calcium in postmenopausal women aged 50-65 years living in Sarajevo area, which hadn’t estrogen defi ciency in their menstrualhistory (in the group of women without osteoporosis amounted to 1195.12 mg) has a positive impact on bone mineral density.

Sign in / Sign up

Export Citation Format

Share Document