A multi-centre prospective study of febrile neutropenia in Norway: Microbiological findings and antimicrobial susceptibility

2005 ◽  
Vol 37 (6-7) ◽  
pp. 455-464 ◽  
Author(s):  
Katrin Sigurdardottir ◽  
Asbjørn Digranes ◽  
Stig Harthug ◽  
Ingerid Nesthus ◽  
Jon-Magnus Tangen ◽  
...  
Keyword(s):  
Febrile Neutropenia ◽  
Prospective Study ◽  
Antimicrobial Susceptibility

scholarly journals Chryseobacterium indologenes as a Rare Pathogen of Bacteremia in Febrile Neutropenia

2021 ◽  
Author(s):  
Begümhan Demir Gündoğan ◽  
Fatih Sağcan ◽  
Elvan Çağlar Çıtak
Keyword(s):  
Risk Factors ◽  
Febrile Neutropenia ◽  
Broad Spectrum ◽  
Antimicrobial Susceptibility ◽  
Neutropenic Fever ◽  
Susceptibility Test ◽  
Antimicrobial Susceptibility Test ◽  
Gram Negative ◽  
Chryseobacterium Indologenes ◽  
Test Result

Chryseobacterium indologenes (C. indologenes) is nonmotile, oxidase-, and indole-positive gram-negative aerobic bacillus. Immunosuppression, comorbidities, use of broad-spectrum antibiotics are known risk factors for C. indologenes-related infections. We report a neutropenic fever caused by C. indologenes in a 16-month-old boy who was treated due to the neuroblastoma. According to the antimicrobial susceptibility test result, he was treated with cephaperazone/sulbactam.

scholarly journals Tubular injury and cell-cycle arrest biomarkers to predict acute kidney injury in noncritically ill children receiving aminoglycosides

2020 ◽  
Vol 14 (10) ◽  
pp. 879-894
Author(s):  
Hayton Chui ◽  
Jillian Caldwell ◽  
Mariya Yordanova ◽  
Vedran Cockovski ◽  
Daniel Fredric ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Acute Kidney Injury ◽  
Febrile Neutropenia ◽  
Prospective Study ◽  
Area Under The Curve ◽  
Kidney Injury ◽  
Tubular Injury ◽  
Early Biomarkers ◽  
Cycle Arrest ◽  
A Prospective Study

Aim: NGAL, IL-18, KIM-1 as well as urinary TIMP2 and IGFBP7 and their mathematical product (TIMP2*IGFBP7) were evaluated for detecting pediatric aminoglycoside acute kidney injury (AG-AKI). Methods: In a prospective study, noncritically ill children received aminoglycosides (AG) ≥3 days. The area under the curve (AUC) for biomarkers to detect AKI was calculated by a) days before AKI onset; b) treatment days. Results: There were 113 AG episodes (68% febrile neutropenia). The AKI group had a higher proportion with febrile neutropenia. The AKI group had significantly lower NGAL 3 days before AKI, as patients with febrile neutropenia had a lower NGAL during AG treatment (p < 0.05). NGAL, IL-18 and TIMP2*IGFBP7 had AUC ≥0.73 at 3, 2 and 2 days before AKI onset. Conclusion: NGAL, IL-18 and TIMP2*IGFBP7 were modest early biomarkers of AG-AKI. Febrile neutropenia was associated with lower NGAL.

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