Composition and biological activities of hogweed [Heracleum sphondyliumL. subsp.ternatum(Velen.) Brummitt] essential oil and its main components octyl acetate and octyl butyrate

Pulicaria genus (fleabane) is characterized by its fragrant odor due to the presence of essential oil (EO). According to the literature reviews, the EO of Pulicaria somalensis O.Hoffm. (Shie) is still unexplored. For the first time, 71 compounds were characterized in EO derived from above-ground parts of P. somalensis collected from Saudi Arabia. Sesquiterpenes represented the main components (91.8%), along with minor amounts of mono-, diterpenes, and hydrocarbons. Juniper camphor (24.7%), α-sinensal (7.7%), 6-epi-shyobunol (6.6%), α-zingiberene (5.8%), α-bisabolol (5.3%), and T-muurolol (4.7%) were characterized as main constituents. The correlation analysis between different Pulicaria species showed that P. somalensis has a specific chemical pattern of the EO, thereby no correlation was observed with other reported Pulicaria species. The EO showed significant allelopathic activity against the weeds of Dactyloctenium aegyptium (L.) Willd. (crowfoot grass) and Bidens pilosa L. (hairy beggarticks). The IC50 value on the germination of D. aegyptium was double that of B. pilosa. The IC50 values on the root growth of B. pilosa and D. aegyptium were 0.6 mg mL−1 each, while the shoot growths were 1.0 and 0.7 mg mL−1, respectively. This variation in the activity could be attributed to the genetic characteristics of the weeds. Moreover, the EO exhibited significant antioxidant effects compared to ascorbic acid. Further studies are necessary to verify if these biological activities of the EO could be attributable to its major compounds.

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Chemical Composition and Biological Activities of the Essential Oil from Artemisia herba-alba Growing Wild in Tunisia

Natural Product Communications ◽

10.1177/1934578x1300800333 ◽

2013 ◽

Vol 8 (3) ◽

pp. 1934578X1300800 ◽

Cited By ~ 2

Author(s):

Ismail Amri ◽

Laura De Martino ◽

Aurelio Marandino ◽

Hamrouni Lamia ◽

Hanana Mohsen ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Biological Activities ◽

Antimicrobial Activities ◽

Lepidium Sativum ◽

Mediterranean Ecosystem ◽

Bacterial Strains ◽

Phytotoxic Activity ◽

Main Components

Aromatic plants can interfere in the Mediterranean ecosystem, mainly by the introduction in the environment of volatile compounds. For this reason, we studied the chemical composition and the possible phytotoxic and antimicrobial activities of the essential oil extracted from leaves of Tunisian Artemisia herba-alba Asso. The chemical composition of the essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. In all, 24 compounds were identified. The main components were camphor (39.1.%), chrysanthenone (15.0%) and cis-thujone (7.8%). The essential oil was evaluated for its in vitro phytotoxic activity against germination and initial radical growth of Raphanus sativus L., Lepidium sativum L., Sinapis arvensis L., Triticum durum L. and Phalaris canariensis L. seeds. The radicle elongation of the five seeds was affected to different extents by the oil, while germination was not affected. The oil, when tested against eight selected bacterial strains, showed low antimicrobial activity. The chemical composition of the oil of A. herba-alba can help in the chemosystematics of this complex genus. However, the recorded biological activities seem to be neither ecologically nor medicinally significant.

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Biological activities of essential oil extracted from leaves of Atalantia sessiflora Guillauminin Vietnam

The Journal of Infection in Developing Countries ◽

10.3855/jidc.12469 ◽

2020 ◽

Vol 14 (09) ◽

pp. 1054-1064 ◽

Cited By ~ 1

Author(s):

Nhan Trong Le ◽

Matthew Gavino Donadu ◽

Duc Viet Ho ◽

Tuan Quoc Doan ◽

Anh Tuan Le ◽

...

Keyword(s):

Essential Oil ◽

Trichomonas Vaginalis ◽

Biological Activities ◽

Antimicrobial Activities ◽

Chemical Compositions ◽

Microdilution Method ◽

Mtt Method ◽

Anti Inflammatory ◽

Main Components ◽

Dsdna Viruses

Introduction: The present study aimed to determine the chemical compositions and bioactivities of the essential oil of Atalantia sessiflora Guillaumin (A. sessiflora), including antibacterial, antimycotic, antitrichomonas, anti-inflammatory and antiviral effects. Methodology: The essential oil from leaves of A. sessiflora was extracted by hydrodistillation using a Clevenger apparatus. Chemical compositions of oil were identified by GC/MS. Antimicrobial and antitrichomonas activity were determined by the microdilution method; anti-inflammatory and antiviral were determined by the MTT method. Results: The average yield of oil was 0.46 ± 0.01% (v/w, dry leaves). A number of 45 constituents were identified by GC/MS. The essential oil comprised four main components. The oil showed antimicrobial activities against Gram-positive strains as Staphylococcus; Gram-negative bacteria such as Klebsiella pneumoniae and Escherichia coli; and finally four Candida species. Enterococcus faecalis and Pseudomonas aeruginosa were least susceptible to the oil of A. sessiflora, as seen in their MIC and MLC values over 16% (v/v). Activity against Trichomonas vaginalis was also undertaken, showing IC50, IC90 and MLC values of 0.016, 0.03 and 0.06% (v/v) respectively, after 48 hours of incubation. The oil of A. sessiflora displayed activity against the nitric oxide generation with the IC50 of 95.94 ± 6.18 µg/mL. The oil was completely ineffective against tested viruses, ssRNA+, ssRNA-, dsRNA, and dsDNA viruses. Conclusions: This is the first yet comprehensive scientific report about the chemical compositions and pharmacological properties of the essential oil of A. sessiflora. Further studies should be done to evaluate the safety and toxicity of A. sessiflora oil.

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Chemical constituents and biological activities against Tribolium castaneum (Herbst) of the essential oil from Citrus wilsonii leaves

Journal of the Serbian Chemical Society ◽

10.2298/jsc140227037c ◽

2014 ◽

Vol 79 (10) ◽

pp. 1213-1222 ◽

Cited By ~ 14

Author(s):

Hai Chen ◽

Kai Yang ◽

Chun You ◽

Shu Du ◽

Qian Cai ◽

...

Keyword(s):

Essential Oil ◽

Tribolium Castaneum ◽

Biological Activities ◽

Chemical Constituents ◽

Positive Control ◽

Contact Toxicity ◽

Fumigant Toxicity ◽

Active Compounds ◽

Active Constituents ◽

Main Components

The essential oil obtained from Citrus wilsonii Tanaka leaves with hydrodistillation was investigated by GC and GC-MS. The main components of the essential oil were identified to be citronellol (16.94%), nerol acetate (10.35%), ?-terpinen (9.85%), citronellal (9.36%) and ?-pinene (6.72%). Among them, the four active constituents, predicted with a bioactivity-test, were isolated and identified as citronellol, ?-terpinene, nerol (neryl) acetate and ?-pinene. It was found that the essential oil of C. wilsonii leaves and isolated compounds possessed fumigant and contact toxicity against Tribolium castaneum adults. The essential oil and ?-terpinen showed strong fumigant toxicity against T. castaneum (LC50 = 8.18 and 4.09 mg L-1). Repellency of the crude oil and active compounds was also determined. Citronellol, neryl acetate and ?-pinene were strongly repellent (100%, 86% and 92%, respectively, at 78.63 nL cm-2, after 2 h treatment) against T. castaneum. The essential oil and citronellol exhibited the same level of repellency compared with the positive control, DEET. The results indicate that the essential oil of C. wilsonii leaves and its active compounds had the potential to be developed as natural fumigants, insecticides and repellents for control of T. castaneum.

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Pistacia lentiscus Hydrosol: Untargeted Metabolomic Analysis and Anti-Inflammatory Activity Mediated by NF-κB and the Citrate Pathway

Oxidative Medicine and Cellular Longevity ◽

10.1155/2020/4264815 ◽

2020 ◽

Vol 2020 ◽

pp. 1-14

Author(s):

Anna Santarsiero ◽

Alberto Onzo ◽

Raffaella Pascale ◽

Maria Assunta Acquavia ◽

Marianna Coviello ◽

...

Keyword(s):

Essential Oil ◽

Biological Activities ◽

Inflammatory Activity ◽

Pistacia Lentiscus ◽

Atp Citrate Lyase ◽

Citrate Lyase ◽

Important Health ◽

Health Promoting ◽

Anti Inflammatory ◽

Main Components

Pistacia lentiscus shows a long range of biological activities, and it has been used in traditional medicine for treatment of various kinds of diseases. Moreover, related essential oil keeps important health-promoting properties. However, less is known about P. lentiscus hydrosol, a main by-product of essential oil production, usually used for steam distillation itself or discarded. In this work, by using ultra-high-resolution ESI(+)-FT-ICR mass spectrometry, a direct identification of four main classes of metabolites of P. lentiscus hydrosol (i.e., terpenes, amino acids, peptides, and condensed heterocycles) was obtained. Remarkably, P. lentiscus hydrosol exhibited an anti-inflammatory activity by suppressing the secretion of IL-1β, IL-6, and TNF-α proinflammatory cytokines in lipopolysaccharide- (LPS-) activated primary human monocytes. In LPS-triggered U937 cells, it inhibited NF-κB, a key transcription factor in inflammatory cascade, regulating the expression of both the mitochondrial citrate carrier and the ATP citrate lyase genes. These two main components of the citrate pathway were downregulated by P. lentiscus hydrosol. Therefore, the levels of ROS, NO, and PGE2, the inflammatory mediators downstream the citrate pathway, were reduced. Results shed light on metabolic profile and anti-inflammatory properties of P. lentiscus hydrosol, suggesting its potential as a therapeutic agent.

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Chemical Composition and Biological Activities of the Essential Oil from Calamintha nepeta Plants from the Wild in Southern Italy

Natural Product Communications ◽

10.1177/1934578x1300800134 ◽

2013 ◽

Vol 8 (1) ◽

pp. 1934578X1300800 ◽

Cited By ~ 2

Author(s):

Emilia Mancini ◽

Laura De Martino ◽

Hanna Malova ◽

Vincenzo De Feo

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Biological Activities ◽

Lepidium Sativum ◽

Campania Region ◽

Phytotoxic Activity ◽

Aerial Parts ◽

Main Components ◽

Lepidium Sativum L

The chemical composition of the essential oil from aerial parts of Calamintha nepeta (L.) Savi, collected in the Campania Region, was obtained by hydrodistillation and analyzed by GC and GC-MS. In all, 42 compounds were identified. The oil was characterized by a prevalence of the sesquiterpenic fraction (80.8%). The main components were 1,10-di- epi-cubenol (18.5%), allo-aromadendrene epoxide (11.4%) and cadalene (5.7%). The essential oil was evaluated for its in vitro potential phytotoxic activity against germination and initial radical growth of Raphanus sativus L., Lepidium sativum L., Sinapis arvensis L., Triticum durum L. and Phalaris canariensis L. seeds. The essential oil showed no antioxidant activity.

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Comparison of Nutritional Compositions and Essential Oil Profiles of Different Parts of a Dill and Two Fennel Cultivars

Foods ◽

10.3390/foods10081784 ◽

2021 ◽

Vol 10 (8) ◽

pp. 1784

Author(s):

Yuanpeng Hao ◽

Jiamu Kang ◽

Xiaoqi Guo ◽

Rui Yang ◽

Yuliang Chen ◽

...

Keyword(s):

Essential Oil ◽

Crude Protein ◽

Biological Activities ◽

Food Additives ◽

Nutritional Composition ◽

Food Preservatives ◽

Aerial Parts ◽

Chemical Profiles ◽

Main Components ◽

Further Development

Fennel and dill are widely used as food additives owing to their various biological activities, such as antioxidants, antimicrobials, food-preservatives, and seasoning capacities. Herein, the nutritional composition and essential oil (EO) chemical profiles of fruits, umbels, stalks, and roots from one dill and two fennel cultivars were evaluated. The fruits had the highest content of crude protein (≥ 15%), crude fat (≥ 8%), and phosphorus (≥ 0.5%), and exhibited the highest total energy (≥ 20 MJ/kg) and EO yield (≥ 2%). Moreover, estragole (86.56% in Fdf), anethole (71.17% in Fhf), fenchone (16.74% in Fhf), limonene (50.19% in Agf), and carvone (42.41% in Agf) were the main components of the EOs generated from the fruits. The chemical profiles of EOs in the roots were significantly different from those of the aerial parts of the fennel and dill; thus, the roots and aerial parts could be distinguished based on myristicin (Variable Importance in Projection (VIP) = 1.90399) and apiol (VIP = 1.85922). The EO components of the aerial parts varied remarkably, and the chemical markers for differentiating these three cultivars were anethole (VIP = 1.36571), estragole (VIP = 1.30292), and carvone (VIP = 1.11947). Overall, our results provide a noteworthy chemical basis for further development of fennel and dill, especially as food additives.

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Ferulago nodosa Subsp. geniculata (Guss.) Troia & Raimondo from Sicily (Italy): Isolation of Essential Oil and Evaluation of Its Bioactivity

Molecules ◽

10.3390/molecules25143249 ◽

2020 ◽

Vol 25 (14) ◽

pp. 3249 ◽

Cited By ~ 2

Author(s):

Natale Badalamenti ◽

Vincenzo Ilardi ◽

Sergio Rosselli ◽

Maurizio Bruno ◽

Filippo Maggi ◽

...

Keyword(s):

Essential Oil ◽

Plant Species ◽

Sulfonic Acid ◽

Biological Activities ◽

Caryophyllene Oxide ◽

Aerial Parts ◽

Lipase Enzyme ◽

Ic50 Value ◽

Main Components ◽

Promising Source

Ferulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area. The object of the present study is Sicilian F. nodosa subsp. geniculata (Guss.) Troia & Raimondo, classified as an endemic F. nodosa subspecies. Aerial parts of this plant species were subjected to hydrodistillation to obtain an essential oil. A total of 93 compounds were identified with 2,3,6-trimethyl benzaldehyde (19.0%), spathulenol (9.0%), (E)-caryophyllene (5.4%), and caryophyllene oxide (5.4%) as the main components. The biological activities of F. nodosa essential oil were also investigated. This oil showed an interesting antioxidant potential in a 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) test (IC50 of 14.05 μg/mL). Additionally, hypoglycemic and antilipidemic effects were evaluated. Lipase enzyme was inhibited with an IC50 value of 41.99 μg/mL. Obtained data demonstrated that F. nodosa could be considered a promising source of bioactive compounds useful for the treatment and management of obesity.

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Compositional Analysis and Antioxidant Activities of Thymus pubescens Essential Oil from Iran

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/1386207323666201230091042 ◽

2020 ◽

Vol 23 ◽

Author(s):

Bahman Nickavar ◽

Elaheh Malekitabar

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Antioxidant Activities ◽

Biological Activities ◽

Compositional Analysis ◽

Detection And Identification ◽

Ic50 Values ◽

Main Components ◽

Β Carotene

Background: The genus Thymus is one of the well-known members of the Lamiaceae, which comprises about 215 species. It is a polymorphic genus in this family. Therefore, possible differences in chemical composition among polymorphs may result in differences in their biological activities. Objective: This study was designed to specify chemical composition in order to assess antioxidant activities and to characterize active constituents of essential oil from Thymus pubescens. Methods: Essential oil was collected by hydrodistillation and was analyzed using GC-MS and GC-FID. Antioxidant activities were evaluated by ABTS radical cation scavenging and β-carotene bleaching inhibition methods. Detection and identification of antioxidant components were performed by TLC-bioautography assay using ABTS•+ reagent. Results: GC analyses indicated the presence of 39 components, accounting for 96.64% of total constituents, with thymol (38.67%), γ-terpinene (7.46%), and p-cymene (5.54%) as the main components. The IC50 values for antioxidant activities were equal to 1.15 (1.05 – 1.25) μg/mL and 0.45 (0.33 – 0.62) μg/mL for ABTS•+ scavenging and β-carotene bleaching inhibition tests, respectively. TLC-bioautograpgy of oil resulted in identification of thymol as the major antioxidant compound. Conclusion: Essential oil exhibited very potent and significant antioxidant activities correlated well with increasing dose in vitro.

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Chemical Composition and Biological Activities of Essential Oils from Fresh Vismia guianensis (Aubl.) Choisy and Vismia cayennensis (Jacq.) Pers. Leaves

Research Society and Development ◽

10.33448/rsd-v10i8.17440 ◽

2021 ◽

Vol 10 (8) ◽

pp. e37410817440

Author(s):

Antonia Tavares Barbosa ◽

Vitor Hugo Neves da Silva ◽

Bruna Yuka Koide da Silva ◽

Aniele da Silva Neves Lopes ◽

Isabel Reis Guesdon ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Biological Activities ◽

Antimicrobial Activities ◽

E Coli ◽

Aerial Parts ◽

Amazon Rain Forest ◽

Vismia Guianensis ◽

Main Components

The Vismia Vand. genus encompasses many species indigenous to the Amazon rain forest where they are popularly known as “Lacre” bark and leaves are widely employed by locals to treat dermatophytoses. The aim of this study was to investigate the chemical composition of essential oils (EOs) extracted from the aerial parts of the species Vismia guianensis (Aubl.) Choisy and Vismia cayennensis (Jacq.) Pers. and to assess their antimicrobial activity against the bacteria Staphylococcus aureus Rosenbach 1884 and Escherichia coli (Migula 1895) Castellani and Chalmers 1919 as well as the fungi Candida albicans (C.P. Robin) Berkhout 1923 and Candida parapsilosis (Ashford) Langeron & Talice 1932. The analysis of the chemical composition of the essential oil extracted from V. guianensis leaves (EOVg) indicated 46 components, of which three sesquiterpenes predominated, namely: (E)-caryophyllene (10.40%), α-copaene (29.45%), and (E)-nerolidol (24.06%). As to the essential oil from V. cayennensis leaves (EOVc), 61 components were identified, of which two oxygenated sesquiterpenes stood out as the main components, namely, germacrone (25.42%) and curzerene (25.29%). EOVg exhibited Minimum Inhibitory Concentration (MIC) of 1.56 µg/mL against the yeast C. parapsilosis whereas EOVc was active against the bacteria E. coli and S. aureus as well as the yeast C. parapsilosis. The results obtained in this study strongly recommend further research on the essential oils in question with a view to isolating and identifying the components responsible for their observed antimicrobial activities.

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