Potentiality Arguments and the Definition of “Human Organism”

2013 ◽  
Vol 13 (1) ◽  
pp. 33-34 ◽  
Author(s):  
Annette Dufner
Keyword(s):  
Human Organism ◽  
Definition Of

scholarly journals Genetic status of patients with colorectal cancer

2021 ◽  
Vol 67 (3) ◽  
pp. 332-337
Author(s):  
Evgeny Kulikov ◽  
Sergey Mertsalov ◽  
Vladimir Grigorenko
Keyword(s):  
Colorectal Cancer ◽  
Genetic Markers ◽  
Diagnostic Methods ◽  
Modern Concept ◽  
Human Organism ◽  
Protective Effects ◽  
Nucleotide Polymorphisms ◽  
Social Significance ◽  
Definition Of ◽  
Work Done

Colorectal cancer remains one of the most common tumors. In the structure of cancer mortality in Russia, tumors of this localization occupy the second place among persons of both sexes, giving way to the cancer of the trachea and bronchi in men, and breast cancer in women, respectively. Despite modern diagnostic methods and approaches to treatment, the problem of colorectal cancer remains acute due to increasing morbidity throughout the world, and recently there has been a downward trend in the average age of patients, which increases the social significance of the problem.  According to the modern concept of carcinogenesis, assessment of the influence of genetic factors on the development of tumors of this localization looks very promising. Research aimed at finding a connection between genetic markers, single-nucleotide polymorphisms of genes and their contribution to the problem of colorectal cancer is one of the most studied directions in modern oncology. In this review, the work done related to the role of gene polymorphisms in the development and therapy of colorectal cancer was evaluated. The works were searched for in the databases of PubMed and Cyber Leninka. The known data about some genes participating in different processes of human organism are given. The data on sensitization and protective effects of polymorphisms of genes, the effect of polymorphisms on the result of treatment of colorectal cancer are presented. The necessity of further work in this direction in order to search for genetic markers and the possibility of implementing the definition of gene polymorphism in clinical practice for personalization of treatment of patients with colorectal cancer are discussed.  

SPECIAL ARTICLE

PEDIATRICS ◽  
1951 ◽  
Vol 8 (2) ◽  
pp. 299-306
Author(s):  
ALFRED H. WASHBURN
Keyword(s):  
Child Development ◽  
Human Development ◽  
Research Council ◽  
Human Growth ◽  
Human Organism ◽  
Research Approach ◽  
Main Theme ◽  
Golden Thread ◽  
Child Research ◽  
Definition Of

EVER since accepting the kind invitation of your President I have known what I wanted to talk to you about tonight. However, when it came to giving my talk a title—a label which would suggest my main theme—then I was stumped. I want to talk a bit about a number of things—about the Child Research Council, about human growth, about education, about pediatric research, and about the responsibilities of the pediatrician in the half century ahead of us. I might then call the talk a "Pediatric Potpourri." The only difficulty with this title is that Mr. Webster, in his fourth definition of the term, says, "a literary production composed of parts brought together without order or bond of connection." While it may be that some of you will decide by the end of this talk that it has been a veritable potpourri yet I hope to succeed in welding a definite "bond of connection" between the various topics discussed. Perhaps the growth, the development, and the adaptation of the human organism is the cementing substance which should run as a golden thread of continuity from the beginning to the end of my discourse. I have used the term "human development" rather than "child development" because my talk tonight is as much concerned with the development of mature and thoughtful pediatricians as it is with the sound and happy development of children who may some day become physicians, lawyers, engineers, businessmen or senators. In fact I'm going to start talking about the Child Research Council not merely as a particular sort of research approach to child development but also as an educational experience for the investigators involved in the venture.

Organ and Machinery Projections in Florensky’s Philosophy and Vertov’s Cinematography

2021 ◽  
pp. 85-96
Author(s):  
Svetlana A. Martynova
Keyword(s):  
Biomedical Engineering ◽  
Human Organism ◽  
New Man ◽  
Dziga Vertov ◽  
Definition Of

My article is dedicated to the Kapp’s theory of organ projections in the first half of the XX century in Russia. I research that the philosopher P. Florensky and the filmmaker Dziga Vertov made the changes to this theory and linked it with the definition of machinery projections purposes and limits. Florensky’s has a goal to analyze new sides of life in an organism by machinery projections. The method of it is the made by a man transference of the functions and contours of technology to an organism. A man thinks about the specificity of an organism and does not allow thinking about it as only less qualitatively working mecha­nism. Vertov has a goal to observe disadvantages of a human organism and reject them via creating of a new man by machinery projections. According to Vertov’s purpose the technology presents an organism as a mechanism via the algorithm of observing and designing. I explain how these conceptions may be useful for researching in the field of bioinformatics and biomedical engineering.

Introductory paper

1966 ◽  
Vol 24 ◽  
pp. 3-5
Author(s):  
W. W. Morgan
Keyword(s):  
Line Intensity ◽  
Classification Scheme ◽  
Two Dimensional ◽  
Spectral Classification ◽  
Dimensional Array ◽  
Rr Lyrae ◽  
Metallic Line ◽  
Introductory Paper ◽  
Parameter Varying ◽  
Definition Of

1. The definition of “normal” stars in spectral classification changes with time; at the time of the publication of theYerkes Spectral Atlasthe term “normal” was applied to stars whose spectra could be fitted smoothly into a two-dimensional array. Thus, at that time, weak-lined spectra (RR Lyrae and HD 140283) would have been considered peculiar. At the present time we would tend to classify such spectra as “normal”—in a more complicated classification scheme which would have a parameter varying with metallic-line intensity within a specific spectral subdivision.

2.2. Working Group 2: Conceptual Definitions of Reference Coordinate Systems for Earth Dynamics

1975 ◽  
Vol 26 ◽  
pp. 21-26
Keyword(s):  
Coordinate System ◽  
Working Group ◽  
General Character ◽  
Coordinate Systems ◽  
Reference Coordinate System ◽  
Group 2 ◽  
Definition Of ◽  
Earth Dynamics

An ideal definition of a reference coordinate system should meet the following general requirements:1. It should be as conceptually simple as possible, so its philosophy is well understood by the users.2. It should imply as few physical assumptions as possible. Wherever they are necessary, such assumptions should be of a very general character and, in particular, they should not be dependent upon astronomical and geophysical detailed theories.3. It should suggest a materialization that is dynamically stable and is accessible to observations with the required accuracy.

Symbiotic Stars at Optical, Infrared and Radio Wavelengths

1979 ◽  
Vol 46 ◽  
pp. 125-149 ◽  
Author(s):  
David A. Allen
Keyword(s):  
Temperature Regime ◽  
Type Star ◽  
Stellar Systems ◽  
Symbiotic Stars ◽  
Lower Excitation ◽  
Definition Of ◽  
Original Type

No paper of this nature should begin without a definition of symbiotic stars. It was Paul Merrill who, borrowing on his botanical background, coined the termsymbioticto describe apparently single stellar systems which combine the TiO absorption of M giants (temperature regime ≲ 3500 K) with He II emission (temperature regime ≳ 100,000 K). He and Milton Humason had in 1932 first drawn attention to three such stars: AX Per, CI Cyg and RW Hya. At the conclusion of the Mount Wilson Ha emission survey nearly a dozen had been identified, and Z And had become their type star. The numbers slowly grew, as much because the definition widened to include lower-excitation specimens as because new examples of the original type were found. In 1970 Wackerling listed 30; this was the last compendium of symbiotic stars published.

Immunoferritin localization of intracellular antigens in positively stained frozen sections

1978 ◽  
Vol 36 (2) ◽  
pp. 168-169
Author(s):  
K. T. Tokuyasu
Keyword(s):  
Surface Tension ◽  
Water Surface ◽  
Thin Layers ◽  
The Other ◽  
Positive Staining ◽  
Frozen Sections ◽  
The Past ◽  
Ultrathin Frozen Sections ◽  
Definition Of

During the past investigations of immunoferritin localization of intracellular antigens in ultrathin frozen sections, we found that the degree of negative staining required to delineate u1trastructural details was often too dense for the recognition of ferritin particles. The quality of positive staining of ultrathin frozen sections, on the other hand, has generally been far inferior to that attainable in conventional plastic embedded sections, particularly in the definition of membranes. As we discussed before, a main cause of this difficulty seemed to be the vulnerability of frozen sections to the damaging effects of air-water surface tension at the time of drying of the sections.Indeed, we found that the quality of positive staining is greatly improved when positively stained frozen sections are protected against the effects of surface tension by embedding them in thin layers of mechanically stable materials at the time of drying (unpublished).

Initial Polymerization Sites Indicated During Mitochondrial Oxidation of Diaminobenzidine after Toluene Treatment

1977 ◽  
Vol 35 ◽  
pp. 408-409
Author(s):  
W. A. Shannon ◽  
M. A. Matlib
Keyword(s):  
Membrane Permeability ◽  
Cytochrome Oxidase ◽  
Rat Liver ◽  
Precise Definition ◽  
Cytochemical Localization ◽  
Oxidative Reaction ◽  
Mitochondrial Oxidation ◽  
Definition Of ◽  
Exogenous Substrates

Numerous studies have dealt with the cytochemical localization of cytochrome oxidase via cytochrome c. More recent studies have dealt with indicating initial foci of this reaction by altering incubation pH (1) or postosmication procedure (2,3). The following study is an attempt to locate such foci by altering membrane permeability. It is thought that such alterations within the limits of maintaining morphological integrity of the membranes will ease the entry of exogenous substrates resulting in a much quicker oxidation and subsequently a more precise definition of the oxidative reaction.The diaminobenzidine (DAB) method of Seligman et al. (4) was used. Minced pieces of rat liver were incubated for 1 hr following toluene treatment (5,6). Experimental variations consisted of incubating fixed or unfixed tissues treated with toluene and unfixed tissues treated with toluene and subsequently fixed.

Application of Scanning Electron Microscopy to Medical Research

1969 ◽  
Vol 27 ◽  
pp. 12-13
Author(s):  
J. D. Hutchison
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Medical Research ◽  
Prosthetic Heart Valve ◽  
School Of Medicine ◽  
Transmission Electron ◽  
Definition Of ◽  
Mechanism Of Failure ◽  
The Brain ◽  
Scanning Electron

When the transmission electron microscope was commercially introduced a few years ago, it was heralded as one of the most significant aids to medical research of the century. It continues to occupy that niche; however, the scanning electron microscope is gaining rapidly in relative importance as it fills the gap between conventional optical microscopy and transmission electron microscopy.IBM Boulder is conducting three major programs in cooperation with the Colorado School of Medicine. These are the study of the mechanism of failure of the prosthetic heart valve, the study of the ultrastructure of lung tissue, and the definition of the function of the cilia of the ventricular ependyma of the brain.

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