scholarly journals Dietary fluted pumpkin seeds induce reversible oligospermia and androgen insufficiency in adult rats

2019 ◽  
Vol 65 (6) ◽  
pp. 437-450 ◽  
Author(s):  
Rex-Clovis C. Njoku ◽  
Sunny O. Abarikwu ◽  
Augustine A. Uwakwe ◽  
Chidimma J. Mgbudom-Okah ◽  
Chioma Yvonne Ezirim
Keyword(s):  
Adult Rats ◽  
Fluted Pumpkin ◽  
Pumpkin Seeds

scholarly journals Proximate and Sensory Evaluation of Fermented Seasonings from Soybean and Fluted Pumpkin Seeds

2020 ◽  
pp. 27-35
Author(s):  
Donald I. Ifediba ◽  
Helen I. Egbuna
Keyword(s):  
Ricinus Communis ◽  
Solid Substrate ◽  
Crude Fiber ◽  
Soybean Seeds ◽  
Solid Substrate Fermentation ◽  
Significant Drop ◽  
Fluted Pumpkin ◽  
Telfairia Occidentalis ◽  
Two Samples ◽  
Pumpkin Seeds

Specialty condiment (ogiri) was produced from seeds of soybean (Glycine max) and fluted pumpkin (Telfairia occidentalis) by spontaneous moist solid substrate fermentation of their pre-processed mash. The two samples coded FSBM and FFPM respectively were evaluated for nutritional quality. Effects of fermentation on proximate values of the seeds were also analyzed. The two samples were further subjected to sensory analysis using commercial brand made  from castor bean (Ricinus communis) seeds coded FCBM as a control. Results show that FFPM was significantly (p < 0.05) higher in ash, crude fiber and protein, but significantly lower in moisture and fat than the FSBM. There was no significant (p > 0.05) difference in carbohydrate content of the two samples. The FFPM recorded significant (p < 0.05) increase in crude fiber, fat and protein, and significant (p < 0.05) decrease in moisture, ash and carbohydrate compared to the values in the fluted pumpkin seeds. The FSBM recorded significant (p < 0.05) rise in fat and protein, but significant drop in moisture, ash, crude fiber and carbohydrate compared to the values in soybean seeds. Sensory results show that FFPM was significantly (p < 0.05) higher than FSBM in flavor and marginally (p > 0.05) different in color, texture, taste and general acceptability. Baring the marginal (p < 0.05) superiority in taste, the FCBM was significantly (p<0.05) lower in every other attributes considered. It follows that good quality fermented condiments can be obtained from cheaper and underutilized oil seeds.

scholarly journals Effects of Hydro-alcoholic Extract of Pumpkin Seeds on Oogenesis Pathway, Liver, and Kidney of Female Rats : The Effects of hydro-alcoholic extract of pumpkin

2020 ◽  
Keyword(s):  
Sexual Maturity ◽  
The Body ◽  
Female Rats ◽  
Alcoholic Extract ◽  
Adult Rats ◽  
Pumpkin Seed ◽  
Immature Rats ◽  
Pumpkin Seeds ◽  
Group 3 ◽  
Experimental Group

Background and Objectives: Pumpkin seed extract can be a good alternative to hormone replacement therapy since it is rich in phytoestrogens. In this regard, the present research aimed to investigate the effect of hydro-alcoholic extract of pumpkin seeds on the oogenesis pathway, liver, and kidney of female rats. Materials and Methods: This experimental study was performed on 64 Wistar female rats (including 32 adults and 32 immature rats). The adult rats were randomly divided into three experimental and one control groups (n=8 per group). Moreover, the immature rats were allocated to groups in a similar manner. The experimental groups 1, 2, and 3 received a hydro-alcoholic extract of pumpkin seed in doses of 20, 50, 100 mg/kg, respectively, via intraperitoneal injection for 21 consecutive days. For the purposes of the study, blood samples were taken one day after the last injection to determine the serum levels of female hormones as well as renal and hepatic factors. The ovaries, livers, and kidneys of the rats were also separated for histological tests. Results: Based on the results, significant increases were observed in the bodyweight of all immature rats; estrogen levels in the adult experimental group 3 and immature experimental groups 2 and 3; progesterone and creatinine levels in the immature experimental group 3; aspartate aminotransferase, total protein, unstable angina (UA), and the renal diameter in the immature experimental groups 1 and 2; follicle-stimulating hormone in the adult experimental group 3 and the immature experimental groups 1 and 2; luteinizing hormone and Graafian follicles in the adult experimental group 3; and atretic follicles in the immature experimental group 1 and 3 (P<0.05). Moreover, significant decreases were observed in the alkaline phosphatase in the adult experimental group 3; total protein, UA, and renal diameter in the immature experimental group 3; diameters of proximal and distal tubule as well as Henle’s loop in all immature rats; diameter of glomerular in the immature experimental groups 1 and 2; diameter of the renal cortex, glomerular, and Bowman's capsule in the adult experimental groups 2 and 3; secondary follicles in the adult experimental group 1, immature experimental groups 1 and 3; and primitive and early follicles in all the adult rats, compared with the control group (P<0.05). Conclusion: Based on the findings, it can be concluded that the pumpkin seeds provide the nutritional needs of the body at the onset of sexual maturity, prepare the body for sexual maturity, and regulate female sex hormones without having adverse effects on the hepatic tissues. However, it must be noted that its consumption at the onset of sexual maturity requires dosage determination and further studies.

The protective effect of fluted pumpkin seeds against atrazine-induced testicular injury

2020 ◽  
pp. 1-11
Author(s):  
Sunny O. Abarikwu ◽  
Amarachukwu L. Oleribe ◽  
Chidimma J. Mgbudom-Okah ◽  
Chigozie L. Onuah ◽  
Chukwuka S. Chikwendu ◽  
...  
Keyword(s):  
Protective Effect ◽  
Fluted Pumpkin ◽  
Pumpkin Seeds ◽  
Testicular Injury

Further Studies on the Ultrastructure of Harderian Gland in Adult Rats

1974 ◽  
Vol 32 ◽  
pp. 288-289
Author(s):  
Alfredo Feria-Velasco ◽  
Guadalupe Tapia-Arizmendi
Keyword(s):  
Fine Structure ◽  
Domestic Fowl ◽  
Animal Species ◽  
Acinar Cells ◽  
Harderian Gland ◽  
Myoepithelial Cells ◽  
The Other ◽  
Albino Rats ◽  
Adult Rats ◽  
Cell Components

The fine structure of the Harderian gland has been described in some animal species (hamster, rabbit, mouse, domestic fowl and albino rats). There are only two reports in the literature dealing on the ultrastructure of rat Harderian gland in adult animals. In one of them the author describes the myoepithelial cells in methacrylate-embbeded tissue, and the other deals with the maturation of the acinar cells and the formation of the secretory droplets. The aim of the present work is to analize the relationships among the acinar cell components and to describe the two types of cells located at the perifery of the acini.

Biodegradable polyester neuroprostheses promote the reconnection of separated peripheral nerve stubs

1992 ◽  
Vol 50 (2) ◽  
pp. 1094-1095
Author(s):  
Beverly L. Giammara ◽  
Jennifer S. Stevenson ◽  
Peggy E. Yates ◽  
Robert H. Gunderson ◽  
Jacob S. Hanker
Keyword(s):  
Image Analysis ◽  
Basement Membrane ◽  
Periodic Acid ◽  
Light And Electron Microscopy ◽  
Computer Assisted ◽  
Type Iii Collagen ◽  
Image Analysis System ◽  
Biodegradable Polyester ◽  
Adult Rats ◽  
Type Iv

An 11mm length of sciatic nerve was removed from 10 anesthetized adult rats and replaced by a biodegradable polyester Vicryl™ mesh sleeve which was then injected with the basement membrane gel, Matrigel™. It was noted that leg sensation and movement were much improved after 30 to 45 days and upon sacrifice nerve reconnection was noted in all animals. Epoxy sections of the repaired nerves were compared with those of the excised segments by the use of a variation of the PAS reaction, the PATS reaction, developed in our laboratories for light and electron microscopy. This microwave-accelerated technique employs periodic acid, thiocarbohydrazide and silver methenamine. It stains basement membrane or Type IV collagen brown and type III collagen (reticulin), axons, Schwann cells, endoneurium and perineurium black. Epoxy sections of repaired and excised nerves were also compared by toluidine blue (tb) staining. Comparison of the sections of control and repaired nerves was done by computer-assisted microscopic image analysis using an Olympus CUE-2 Image Analysis System.

High-voltage EM description of the types and distribution of sensory endings in the inner conical body of the rat vibrissal follicle-sinus complex

1990 ◽  
Vol 48 (3) ◽  
pp. 410-411
Author(s):  
Tony M. Mosconi ◽  
Min J. Song ◽  
Frank L. Rice
Keyword(s):  
Mammalian Species ◽  
Dorsal Side ◽  
Hair Shaft ◽  
Sensory Innervation ◽  
Conical Body ◽  
Adult Rats ◽  
Perpendicular Plane ◽  
Ultrastructural Studies ◽  
Unmyelinated Axons ◽  
Sensory Endings

Whiskers or vibrissal follicle-sinus complexes (F-SCs) on the snouts of many mammalian species are structures that have complex, dense sensory innervation. The innervation of F-SCs is remarkably similar in all species with the exception of one site - the inner conical body (ICB). The ICB is an elongated cylindrical structure that encircles the hair shaft near the neck of the follicle. This site has received only cursory attention in ultrastructural studies of the F-SCAdult rats were perfused after the method of Renehan and Munger2. F-SCs were quartered longitudinally and embedded separately in Epon-Araldite. Serial 0.25 μm sections were cut in either the longitudinal or perpendicular plane through the ICB and examined with an AEI EM7 1.2 MV HVEM (Albany, NY) at 1000 KV. Sensory endings were reconstructed from serial micrographs through at least 20 μm in the longitudinal plane and through 10 μm in the perpendicular plane.From two to six small superficial vibrissal nerves converge upon the neck of the F-SC and descend into the ICB. The nerves branch into smaller bundles of myelinated and unmyelinated axons along the dorsal side of the hair shaft.

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