scholarly journals Lower Prevalence of Diabetes Mellitus in Patients with Klebsiella pneumoniae Primary Liver Abscess Caused by Isolates of K1/K2 than with Non-K1/K2 Capsular Serotypes

2007 ◽  
Vol 45 (11) ◽  
pp. 1529-1530 ◽  
Author(s):  
W.-L. Yu ◽  
K.-S. Chan ◽  
W.-C. Ko ◽  
C.-C. Lee ◽  
Y.-C. Chuang
Keyword(s):  
Diabetes Mellitus ◽  
Klebsiella Pneumoniae ◽  
Liver Abscess ◽  
Lower Prevalence ◽  
Prevalence Of Diabetes Mellitus

scholarly journals Characteristics of gas-forming pyogenic liver abscess caused by Klebsiella pneumoniae and Clostridi perfringens

2019 ◽  
Author(s):  
Zheng-Yang Chen ◽  
Nan Jiang ◽  
Song Guo ◽  
Bin-Bin Li ◽  
Jia-Qi Yang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Klebsiella Pneumoniae ◽  
Liver Abscess ◽  
Pyogenic Liver Abscess ◽  
Review Of Literature ◽  
Manual Search ◽  
Life Threatening ◽  
Low Incidence ◽  
Background Gas ◽  
Prevalence Of Diabetes Mellitus

Abstract Background: Gas-forming pyogenic liver abscess is a life-threatening disease with poor prognosis commonly caused by 2 bacteria, Klebsiella pneumoniae and Clostridium perfringens . Due to its low incidence and associated high mortality rate, it is important to study the biological characteristics of the disease. The aim of this study was to conduct a worldwide review of literature on gas-forming pyogenic liver abscess caused by K. pneumoniae and C. perfringens . Methods: We searched PubMed and Web of Science databases from January 2009 to March 2019, with published in English. All relevant articles were accessed in full text. The manual search included references of retrieved articles. Finally, 35 publications were selected for review. Results: The results showed that more cases of gas-forming pyogenic liver abscess in Asia were caused by K. pneumoniae than by C. perfringens (P=0.011). The prevalence of diabetes mellitus in patients with gas-forming pyogenic liver abscess caused by K. pneumoniae was higher than caused by C. perfringens (P=0.032). The survival rate of patients with gas-forming pyogenic liver abscess caused by K. pneumoniae who received surgical debridement or drainage was higher than caused by C. perfringens (P=0.002). Conclusions: The prevalence of diabetes mellitus was higher in patients with gas-forming pyogenic liver abscess caused by K. pneumoniae than in patients caused by C. perfringens .

scholarly journals A Rare Case of Recurrent Klebsiella pneumoniae Liver Abscess

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Magdelene Amoateng ◽  
Pius Osei-Bagyina ◽  
Reba Varughese ◽  
Achsah Mathew ◽  
Ishan Malhotra
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Klebsiella Pneumoniae ◽  
Liver Abscess ◽  
High Mortality ◽  
Rare Case ◽  
Pyogenic Liver Abscess ◽  
Important Risk Factor ◽  
Aggressive Treatment

Klebsiella pneumoniae liver abscess (KPLA) is an emerging syndrome with the initial cases described in Taiwan in the 1980s. There is high mortality with this condition, and immediate aggressive treatment is necessary. Diabetes mellitus (D.M.) is the single most important risk factor for developing KPLA. Here, we describe a rare case of recurrent cryptogenic Klebsiella pneumoniae pyogenic liver abscess (KPLA) in a young man with poorly controlled type 1 D.M.

scholarly journals Case of Pyogenic Liver Abscesses Caused by Klebsiella Pneumoniae

2018 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Liver Abscess ◽  
Anaerobic Bacteria ◽  
Pyogenic Liver Abscess ◽  
Hepatobiliary Disease ◽  
Liver Abscesses ◽  
Patients With Diabetes ◽  
Aerobic And Anaerobic

Liver abscess is a serious intraabdominal infection can be due to result of bacteria, fungi, or parasites infection. Until the end of the last century, pyogenic liver abscesses were predominantly caused by mixed aerobic and anaerobic bacteria, the most frequent isolate being Escherichia coli [1]. Klebsiella pneumoniae (K.pneumoniae) is a known cause of pyogenic liver abscess (PLA) in the absence of hepatobiliary disease. In settings of hepatic infection, it has also been known to cause disseminated infections including meningitis and endopthalmitis. Patients with diabetes mellitus and the preexisting hepatobiliary disease are particularly susceptible to infection as well as those from Southeast Asia [2]. We present a case of Klebsiella liver abscess with bacteremia.

scholarly journals Ventriculitis Associated with Liver Abscess Caused by Klebsiella Pneumoniae

2020 ◽  
Vol 38 (3) ◽  
pp. 210-213
Author(s):  
Yongwoo Lee ◽  
Young-Mok Song
Keyword(s):  
Diabetes Mellitus ◽  
Central Nervous System ◽  
Nervous System ◽  
Klebsiella Pneumoniae ◽  
Antibiotic Treatment ◽  
Liver Abscess ◽  
Metastatic Infection ◽  
Appropriate Treatment ◽  
The Central Nervous System ◽  
Prompt Diagnosis

<i>Klebsiella pneumoniae</i> has been recognized to cause an invasive syndrome characterized by liver abscess and its metastatic infection. The characteristics of metastatic infection involving the central nervous system in this invasive syndrome are poorly understood. The authors report an 84-year-old woman with diabetes mellitus who developed liver abscess caused by <i>K. pneumoniae</i>, complicated with ventriculitis. The patient died despite the antibiotic treatment. Ventriculitis is a rare CNS complication of <i>K. pneumoniae</i> invasive syndrome and requires prompt diagnosis for the appropriate treatment.

scholarly journals Diabetes mellitus epidemiology in Daghestan

1993 ◽  
Vol 39 (1) ◽  
pp. 21-24 ◽  
Author(s):  
S. A. Abusuyev ◽  
J. G. Khachirov ◽  
A. A. Akhmedkhanov
Keyword(s):  
Diabetes Mellitus ◽  
Ethnic Groups ◽  
Type Ii Diabetes ◽  
Preventive Measures ◽  
Urban Residents ◽  
Type Ii ◽  
Lower Prevalence ◽  
Annual Increment ◽  
Develop Diabetes Mellitus ◽  
Prevalence Of Diabetes Mellitus

The authors analyze the prevalence of diabetes mellitus in Daghestan, a republic with various climatic and geographic zones, whose population belongs to a great variety of ethnic groups, over 1987-1991. The findings evidence a lower prevalence of this condition in Daghestan than in other regions, but there is a trend to an annual increment in the morbidity, mostly at the expense of Type II diabetes. The urban residents of Daghestan more often develop the disease, may be due to the fact that wine-making industry is concentrated mainly in town. In the country diabetes mellitus in more incident on the planes, less incident in the foothills, and still less incident in the mountains. The highlanders, when they come to the planes, develop diabetes mellitus as frequently as the residents of the planes. Of the ethnic groups the Russians suffer from the disease most frequently, then come the Kumyks, Lakts, Darghines, Lezghines, Aguls, Tabasaranes; the Avares and Rutules are the least frequent among the diabetics. Preventive measures should be concentrated mostly in towns and on the planes. These specific features of diabetes mellitus epidemiology should be taken into consideration when organizing a net of endocrine service.

Pyogenic Liver Abscesses Patients With Diabetes Mellitus Induced by Klebsiella Pneumoniae Are More Prone to Organ Dysfunction

2021 ◽  
Author(s):  
Mingming Xue ◽  
Xiangpeng Zeng ◽  
Feixiang Xu ◽  
Mian Shao ◽  
Yilin Yang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Klebsiella Pneumoniae ◽  
Organ Dysfunction ◽  
Liver Abscess ◽  
High Throughput ◽  
Inflammatory Markers ◽  
High Throughput Sequencing ◽  
Glycated Albumin ◽  
Density Lipoprotein ◽  
Significant Difference

Abstract Background Diabetes mellitus (DM) has become a common risk factor for pyogenic liver abscess (PLA) patients, Klebsiella pneumoniae is a primary pathogen of PLA (KPLA). The purpose of this study was to evaluate the clinical and microbiological characteristics in PLA patients with or without DM induced by Klebsiella pneumoniae or not.Methods The clinical data of the total 557 PLA patients were collected in Zhongshan Hospital from January 2015 to December 2020. The liver abscess were confirmed using abdominal ultrasound (US)，computerized tomography (CT), and/or magnetic resonance imaging (MRI). The 557 patients were divided into two groups, PLA with DM and PLA without DM. In the group of PLA with DM, the patients were further separated into KPLA with DM and non-KPLA with DM.Results The total of 557 patients with PLA were analyzed, 225 (40.40%) patients comorbided DM. Among PLA patients with DM, there is a higher proportion of patients with hypertension (42.22%) and fatty liver diseases (38.67%), the most common clinical manifestation is frail and fatigue (18.22%), and more likely to progress to sepsis and metastatic infections such as periorbital infection. The PLA patients with DM have higher inflammatory markers (WBC, N%, CRP, ESR and PCT). There was significant difference between the group of PLA with DM and PLA without DM in the percentage of neutrophils, liver enzymes, albumin, glucose metabolism (blood glucose, glycated hemoglobin and glycated albumin), lipid metabolism (triglycerides, low density lipoprotein, high density lipoprotein), blood sodium and chlorine, blood urea nitrogen and higher heart markers ( proBNP and CK-MB). In KPLA patients with DM compared with non-KPLA with DM, inflammatory markers (WBC, N%, CRP, ESR and PCT), liver function index (TB, CB, ALT, AST, ALP and r-GT) and cardiac markers (cTnT and proBNP) are more higher. The level of albumin, serum sodium and ferritin are more lower between the KPLA patients with DM and non-KPLA with DM. Detection of liver abscess by high-throughput sequencing is more sensitive and accurate. There was no in-hospital mortality.Conclusions The study found that in the PLA patients with diabetic DM, Klebsiella pneumoniae infection is the most common, which is more prone to organ dysfunction and electrolyte disorder. High-throughput sequencing can help early diagnosis and accurate treatment of PLA patients.

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