A new type of silica-coated Gd2(CO3)3:Tb nanoparticle as a bifunctional agent for magnetic resonance imaging and fluorescent imaging

2012 ◽  
Vol 23 (20) ◽  
pp. 205103 ◽  
Author(s):  
Yanli Wu ◽  
Xianzhu Xu ◽  
Qun Tang ◽  
Yongxiu Li
Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1230
Author(s):  
Vega Lloveras ◽  
José Vidal-Gancedo

The search for new biomedical applications of dendrimers has promoted the synthesis of new radical-based molecules. Specifically, obtaining radical dendrimers has opened the door to their use in various fields such as magnetic resonance imaging, as anti-tumor or antioxidant agents, or the possibility of developing new types of devices based on the paramagnetic properties of organic radicals. Herein, we present a mini review of radical dendrimers based on polyphosphorhydrazone, a new type of macromolecule with which, thanks to their versatility, new metal-free contrast agents are being obtained, among other possible applications.


Nanoscale ◽  
2014 ◽  
Vol 6 (5) ◽  
pp. 2855-2860 ◽  
Author(s):  
Haibo Wang ◽  
Wei Lu ◽  
Tianmei Zeng ◽  
Zhigao Yi ◽  
Ling Rao ◽  
...  

A new type of multi-functional NaErF4 nanoprobe with enhanced red upconversion emission was developed and used for in vitro cell, in vivo X-ray and T2-weighted magnetic resonance imaging for the first time.


Inorganics ◽  
2019 ◽  
Vol 7 (5) ◽  
pp. 68 ◽  
Author(s):  
Éva Tóth ◽  
Célia S. Bonnet

This article aimed at reviewing the advances on the development of paramagnetic complexes used as chemical exchange saturation transfer agents in magnetic resonance imaging. This relatively new type of contrast opens new avenues in the development of MRI probes for molecular imaging, and coordination chemistry lies at the center of such advances. Strategies to detect important biomarkers such as pH, cations, anions, metabolites, enzyme, and O2 were described. The current challenges, limitations, and opportunities in this field of research were discussed.


2015 ◽  
Vol 3 (26) ◽  
pp. 5172-5181 ◽  
Author(s):  
M. Zubair Iqbal ◽  
Xuehua Ma ◽  
Tianxiang Chen ◽  
Ling'e Zhang ◽  
Wenzhi Ren ◽  
...  

Silica-coated-SPIONPs-T1 enhanced MRI contrast agents.


2012 ◽  
Vol 51 (17) ◽  
pp. 9508-9516 ◽  
Author(s):  
Jian Luo ◽  
Wei-Sheng Li ◽  
Peng Xu ◽  
Li-Yi Zhang ◽  
Zhong-Ning Chen

2018 ◽  
Vol 6 (8) ◽  
pp. 2209-2218 ◽  
Author(s):  
Siqi Wang ◽  
Wenzhi Ren ◽  
Jianhua Wang ◽  
Zhenqi Jiang ◽  
Madiha Saeed ◽  
...  

New type of black TiO2 nanoprobes with high long relaxation rate and significant targeting capability were prepared for magnetic resonance imaging guided photothermal therapy in pancreatic stem-like cells.


RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 39719-39725 ◽  
Author(s):  
Xiaofeng Luo ◽  
Dechao Niu ◽  
Yao Wang ◽  
Yungang Zhai ◽  
Jianzhuang Chen ◽  
...  

A new type of magnetite-loaded dual-mesoporous silica nanoplatform has been successfully developed for MR imaging and efficient drug delivery.


2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Rakesh Sharma ◽  
Jeong-Won Seo ◽  
Soonjo Kwon

Nitric oxide (NO) biosensors are novel tools for real-time bioimaging of tissue oxygen changes and physiological monitoring of tissue vasculature. Nitric oxide behavior further enhances its role in mapping signal transduction at the molecular level. Spectrometric electron paramagnetic resonance (EPR) and fluorometric imaging are well known techniques with the potential forin vivobioimaging of NO. In tissues, NO is a specific target of nitrosyl compounds for chemical reaction, which provides a unique opportunity for application of newly identified NO biosensors. However, the accuracy and sensitivity of NO biosensors still need to be improved. Another potential magnetic resonance technique based on short term NO effects on proton relaxation enhancement is magnetic resonance imaging (MRI), and some NO biosensors may be used as potent imaging contrast agents for measurement of tumor size by MRI combined with fluorescent imaging. The present review provides supporting information regarding the possible use of nitrosyl compounds as NO biosensors in MRI and fluorescent bioimaging showing their measurement limitations and quantitative accuracy. These new approaches open a perspective regarding bioimaging of NO and thein vivoelucidation of NO effects by magnetic resonance techniques.


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