Performance improvement of magneto-acousto-electrical tomography for biological tissues with sinusoid-Barker coded excitation

2018 ◽  
Vol 27 (9) ◽  
pp. 094302 ◽  
Author(s):  
Zheng-Feng Yu ◽  
Yan Zhou ◽  
Yu-Zhi Li ◽  
Qing-Yu Ma ◽  
Ge-Pu Guo ◽  
...  
2021 ◽  
Author(s):  
Elena Renzhiglova

This thesis reports our research on developing a new method to image the electric conductivity and relative permittivity of biological tissues. The first method is Differential Frequency Magneto-Acousto-Electrical Tomography (DF-MAET) to image the electrical impedance of biological tissues with high spatial resolution. It is shown that DF-MAET signal is caused by the vibrations of the sample at a difference frequency (DF) because of the radiation force. In the second method, we investigated the possibility of using a novel mechanism for imaging the electrical permittivity of biological tissues. Theoretical study shows that a magnetic moment will be produced in biological tissues when both and ultrasound wave and an electrical field exist in the tissue. We report the results to detect this magnetic moment with both coils and electrodes attached to the tissue. We were able to detect the signal with electrodes, but its frequency dependence indicates that this signal is due to the impedance modulation by ultrasound, and that it is not related to the relative permittivity. Finally, we studied the ultrasonic vibration potentials generated in fat and muscle tissues.


2021 ◽  
Author(s):  
Syed Haider

This thesis is about investigating a potential imaging modality, magneto-acousto-electrical tomography (MAET), to provide high-spatial-resolution images of lead field current density and electrical impedance of biological tissues. A lead field current density distribution is the one obtained when a current/voltage source is applied to a sample via a pair of electrodes. The lead field current density distribution can potentially be used to obtain electrical impedance distribution which is helpful in differentiating normal and cancerous tissues. To image lead filed current density, instead of directly applying a current/voltage source to the sample, the sample is placed in a static magnetic field and an ultrasound is focused on it to simulate a point like current dipole source in the focal zone. Electrodes are used to detect the voltage/current generated by the ultrasound in the sample, which according to the reciprocity theorem is proportional to a component of the lead field current density.


2021 ◽  
Author(s):  
Syed Haider

This thesis is about investigating a potential imaging modality, magneto-acousto-electrical tomography (MAET), to provide high-spatial-resolution images of lead field current density and electrical impedance of biological tissues. A lead field current density distribution is the one obtained when a current/voltage source is applied to a sample via a pair of electrodes. The lead field current density distribution can potentially be used to obtain electrical impedance distribution which is helpful in differentiating normal and cancerous tissues. To image lead filed current density, instead of directly applying a current/voltage source to the sample, the sample is placed in a static magnetic field and an ultrasound is focused on it to simulate a point like current dipole source in the focal zone. Electrodes are used to detect the voltage/current generated by the ultrasound in the sample, which according to the reciprocity theorem is proportional to a component of the lead field current density.


Author(s):  
Lee D. Peachey ◽  
Clara Franzini-Armstrong

The effective study of biological tissues in thick slices of embedded material by high voltage electron microscopy (HVEM) requires highly selective staining of those structures to be visualized so that they are not hidden or obscured by other structures in the image. A tilt pair of micrographs with subsequent stereoscopic viewing can be an important aid in three-dimensional visualization of these images, once an appropriate stain has been found. The peroxidase reaction has been used for this purpose in visualizing the T-system (transverse tubular system) of frog skeletal muscle by HVEM (1). We have found infiltration with lanthanum hydroxide to be particularly useful for three-dimensional visualization of certain aspects of the structure of the T- system in skeletal muscles of the frog. Specifically, lanthanum more completely fills the lumen of the tubules and is denser than the peroxidase reaction product.


Author(s):  
William H. Massover

Stereoscopic examination of thick sections of fixed and embedded biological tissues by high voltage electron microscopy has been shown to allow direct visualization of three-dimensional fine structure. The present report will consider the occurrence of some new technical problems in specimen preparation and Image interpretation that are not common during lower voltage studies of thin sections.Thick Sectioning and Tissue Coloration - Epon sections of 0.5 μm or more that are cut with glass knives do not have a uniform thickness as Judged by their interference colors; these colors change with time during their flotation on the knife bath, and again when drying onto the specimen support. Quoted thicknesses thus must be considered only as rough estimates unless measured in specific regions by other methods. Chloroform vapors do not always result in good spreading of thick sections; however, they will spread spontaneously to large degrees after resting on the flotation bath for several minutes. Ribbons of thick sections have been almost impossible to obtain.


Author(s):  
C.A. Baechler ◽  
W. C. Pitchford ◽  
J. M. Riddle ◽  
C.B. Boyd ◽  
H. Kanagawa ◽  
...  

Preservation of the topographic ultrastructure of soft biological tissues for examination by scanning electron microscopy has been accomplished in the past by using lengthy epoxy infiltration techniques, or dehydration in ethanol or acetone followed by air drying. Since the former technique requires several days of preparation and the latter technique subjects the tissues to great stress during the phase change encountered during air-drying, an alternate rapid, economical, and reliable method of surface structure preservation was developed. Turnbill and Philpott had used a fluorocarbon for the critical point drying of soft tissues and indicated the advantages of working with fluids having both moderately low critical pressures as well as low critical temperatures. Freon-116 (duPont) which has a critical temperature of 19. 7 C and a critical pressure of 432 psi was used in this study.


Author(s):  
Bruno Schueler ◽  
Robert W. Odom

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) provides unique capabilities for elemental and molecular compositional analysis of a wide variety of surfaces. This relatively new technique is finding increasing applications in analyses concerned with determining the chemical composition of various polymer surfaces, identifying the composition of organic and inorganic residues on surfaces and the localization of molecular or structurally significant secondary ions signals from biological tissues. TOF-SIMS analyses are typically performed under low primary ion dose (static SIMS) conditions and hence the secondary ions formed often contain significant structural information.This paper will present an overview of current TOF-SIMS instrumentation with particular emphasis on the stigmatic imaging ion microscope developed in the authors’ laboratory. This discussion will be followed by a presentation of several useful applications of the technique for the characterization of polymer surfaces and biological tissues specimens. Particular attention in these applications will focus on how the analytical problem impacts the performance requirements of the mass spectrometer and vice-versa.


2020 ◽  
Vol 1 (3) ◽  
pp. 316-324
Author(s):  
Syukrani Kadir

periodically in preparing learning plans, implementing learning, assessing learning achievement, carrying out follow-up assessments of student learning achievement that can improve teacher performance. This performance improvement is through periodic collaborative educational supervision. Based on the results of educational supervision in cycle I and cycle II, teacher performance increased, namely in cycle I, teacher performance in preparing learning plans in cycle I reached 71.98%, while cycle II was 92.44%. Teacher performance in implementing learning cycle I reached 72.44% while cycle II reached 93.81%. Teacher performance in assessing learning achievement in cycle Im reached 81.30% while cycle II was 90.56%. Teacher performance in carrying out follow-up assessments of student learning achievement in the first cycle reached 59.76% while the second cycle was 83.00%. Thus, the average action cycle II was above 75.00%. Based on the results of this study, it can be concluded that the teacher's performance has increased in preparing learning plans, implementing learning, assessing learning achievement, carrying out follow-up assessments of student learning achievement.


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