scholarly journals Adaptogenic effect of the ethanol extract of mangosteen peel (Garcinia mangostana L.) in mice (Mus musculus) blood profile using the Swimming Endurance Test

2019 ◽  
Vol 343 ◽  
pp. 012037
Author(s):  
A W Jamaluddin ◽  
A M S Apada ◽  
K I Prahesti
Keyword(s):  
Mus Musculus ◽  
Ethanol Extract ◽  
Endurance Test ◽  
Garcinia Mangostana ◽  
Blood Profile ◽  
Mangosteen Peel ◽  
Adaptogenic Effect ◽  
Swimming Endurance

scholarly journals Kadar Polifenol Total Ekstrak Etanol Kulit Buah Manggis (Garcinia mangostana) Pada Variasi Asal Daerah

2017 ◽  
Vol 3 (1) ◽  
pp. 22 ◽  
Author(s):  
Any Guntarti
Keyword(s):  
Ethanol Extract ◽  
Total Phenol Content ◽  
Ammonia Vapor ◽  
Phenol Content ◽  
Garcinia Mangostana ◽  
Mangosteen Peel ◽  
Fruit Skin ◽  
Specific Parameter ◽  
Qualitative Test ◽  
Parameter Test

Background:Mangosteen peel is one of the waste of mangosteen, that nowadays have already utilized much to manage health problems. One of the ingredients in the mangosteen fruit skin is a polyphenols. Objective: to determine the polyphenols content of the ethanol extract of mangosteen peel variations based on different regions. Methods: Powder of dried mangosteen peel that come from 3 difference areas, Sumatera (Pekanbaru), Jawa (Yogyakarta) and Kalimantan (Martapura) extracted with ethanol 70% by multilevel maceration. Extract that obtained than tested specific parameter form of qualitative test of polyphenols compounds with FeCl3, AlCl3, ammonia vapor, Folin Ciucalteau and tannin test. Determination level of polyphenols (Gallic acid) with visible spectrophotometri after reacted with Folin Ciucalteau reagent. Results: The result of this research was quality test of extract etanol 70% Specific parameter test total phenol content (mg GAE/g ekstrak) from Sumatera, Jawa and Kalimantan are :824.13 (mg GAE/g ekstrak); 155,86 (mg GAE/g ekstrak); 688,9 (mg GAE/g ekstrak). Conclusions: There were difference in contents of polyphenol of mangosteen peel origin among Sumatera, Jawa and Kalimantan. 

scholarly journals Pengaruh Ekstrak Kulit Buah Manggis (Garcinia mangostana L.) terhadap Histologis Pankreas Mencit (Mus musculus L. Swiss Webster) yang Diinduksi Sukrosa

2018 ◽  
Vol 19 (1) ◽  
pp. 100-112
Author(s):  
Ramadhan Sumarmin
Keyword(s):  
Blood Glucose ◽  
Alternative Medicine ◽  
Mus Musculus ◽  
Islet Cells ◽  
Negative Control ◽  
Garcinia Mangostana ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Mangosteen Peel ◽  
Peel Extract

Diabetes Mellitus (DM) is a metabolic disorder caused by lack of insulin which islet cells of Langerhans in the pancreas were damaged or decreased. DM treatment is quite expensive so it takes the alternative medicine. Ones of alternative medicine using Mangosteen Fruit pod. The pod of the mangosteen fruit have xanton flavonoid compounds, which function as antioxidants that can lower blood glucose levels and improve pancreatic cells. The study aimed to determine the effect of mangosteen rind extract (Garcinia mangostana L.) to display the pancreatic histology of mice (Mus musculus L. Swiss Webster) induced male sucrose. This study used Completely Randomized Design (CRD) with 5 treatments and 5 replications. treatments is P1 (positive control), sucrose 0.8 g/kg (negative control / P2), sucrose + 200 mg/kg of mangosteen peel extract (P3), sucrose + 400 g/kg of mangosteen peel extract ( P4), sucrose + 600 mg/kg of mangosteen peel extract (P5). Observations quantitatively to determine blood glucose levels and the number of Langerhans islet cells after 5 days and 4 days inducing the extract. Data were analyzed by ANOVA, if there is a difference will be continued with Duncan test at the 0.05 significance level. The results showed the average number of Langerhans islet cells 205.6 (P1), 134.0 cells (P2), 114.2 cells (P3), 193.0 cell (P4), and 181.8 cells (P5). From the results obtained in the analysis of data obtained Fhitung<Ftabel significant at 0.05, so it can be concluded that the mangosteen rind extract has no effect on pancreatic histological induced male mice sucrose.

scholarly journals Kadar Polifenol Total Ekstrak Etanol Kulit Buah Manggis (Garcinia mangostana) Pada Variasi Asal Daerah

2017 ◽  
Vol 3 (1) ◽  
pp. 22 ◽  
Author(s):  
Any Guntarti
Keyword(s):  
Ethanol Extract ◽  
Total Phenol Content ◽  
Ammonia Vapor ◽  
Phenol Content ◽  
Garcinia Mangostana ◽  
Mangosteen Peel ◽  
Fruit Skin ◽  
Specific Parameter ◽  
Qualitative Test ◽  
Parameter Test

Background:Mangosteen peel is one of the waste of mangosteen, that nowadays have already utilized much to manage health problems. One of the ingredients in the mangosteen fruit skin is a polyphenols. Objective: to determine the polyphenols content of the ethanol extract of mangosteen peel variations based on different regions. Methods: Powder of dried mangosteen peel that come from 3 difference areas, Sumatera (Pekanbaru), Jawa (Yogyakarta) and Kalimantan (Martapura) extracted with ethanol 70% by multilevel maceration. Extract that obtained than tested specific parameter form of qualitative test of polyphenols compounds with FeCl3, AlCl3, ammonia vapor, Folin Ciucalteau and tannin test. Determination level of polyphenols (Gallic acid) with visible spectrophotometri after reacted with Folin Ciucalteau reagent. Results: The result of this research was quality test of extract etanol 70% Specific parameter test total phenol content (mg GAE/g ekstrak) from Sumatera, Jawa and Kalimantan are :824.13 (mg GAE/g ekstrak); 155,86 (mg GAE/g ekstrak); 688,9 (mg GAE/g ekstrak). Conclusions: There were difference in contents of polyphenol of mangosteen peel origin among Sumatera, Jawa and Kalimantan. 

scholarly journals Test of the Effectiveness of Anti-Dyslipedemia Extract Ethanol Mangosteen Peel (Garcinia Mangostana L.) in Male Mice Fed a High-Fat Diet

2021 ◽  
Vol 4 (1) ◽  
pp. 1-12
Author(s):  
Zhang Yu ◽  
Florenly ◽  
Liena ◽  
Fioni
Keyword(s):  
Treatment Group ◽  
High Fat Diet ◽  
Ethanol Extract ◽  
Control Group ◽  
High Fat ◽  
Garcinia Mangostana ◽  
Mangosteen Peel ◽  
Significant Difference ◽  
Male Wistar Rats ◽  
Entire Treatment

Dyslipidemia is a major risk factor for atheroscler heart disease, stroke, and is often defined as abnormalities or disruption of lipid metabolism. Garcinia mangostana L. is famous for its anti-inflammatory properties and is used in the treatment of skin infections and wounds. The main phytochemicals present in this species are anisoprenylated xanthone, many reports of biological effects, such as antioxidant, pro-apoptosis, anti-proliferative, anti-nosiseptif, anti-inflammatory, neuroprotective, hypoglycemic, and anti-obesity. This study aims to find out the effectiveness of mangosteen peel ethanol extract as an anti-dyslipidemia in male wistar rats given a high-fat diet. This type of research is experimental with a Pre-test approach and Post-test group only control design. The samples used were mangosteen peel ethanol extract and male wistar rats, with the size of the sample calculated with Federer's formula. Analyze data with the One-Way Anova Test if the data is normally distributed with advanced tests in the form of Post Hoc Tukey HSD tests to see real differences between treatments. The results of the total cholesterol study in the entire treatment group of mice showed a significant difference in P values < 0.05. Triglyceride levels in the entire treatment group also showed significant differences, this can be seen from the value of P < 0.05 (Value P = 0.029). LDL levels also showed significant differences across the treatment group, which can be seen from the P value of < 0.05. HDL levels make a significant difference in the value of P < 0.05 (Value P = 0.029). SGOT and SGPT levels in the entire group of rat treatment showed significant differences, this was seen from the value of P < 0.05. The conclusion that mangosteen peel ethanol extract significantly lowered total cholesterol, triglyceride levels, LDL levels, SGOT levels compared to the control group. Mangosteen peel ethanol extract can significantly increase HDL levels compared to the control group.

scholarly journals Synthesis and Characterization of Bacterial Cellulose - Garcinia mangostana Extract as Anti Breast Cancer Biofilm Candidate

2017 ◽  
Vol 30 ◽  
pp. 76-85 ◽  
Author(s):  
Waya Rahmaning Gusti Agrippina ◽  
Prihartini Widiyanti ◽  
Helmy Yusuf
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Bacterial Cellulose ◽  
Mtt Assay ◽  
Breast Cancer Cells ◽  
Ethanol Extract ◽  
Ethanol Solution ◽  
Garcinia Mangostana ◽  
Mangosteen Peel ◽  
Peel Extract

In Indonesia, breast cancer is noted as the most common cancer in women. Accordingly, this research was conducted to synthesize biofilm from bacterial cellulose by adding ethanol extract of mangosteen peel. The pellicle of bacterial cellulose was soaked in a 100 mL ethanol solution of mangosteen peel extract varied by 0.5%, 1%, 1.5%, and 2% v/v. The samples were characterized using the SEM, FTIR, and MTT Assay using the T47D breast cancer cells. The results using the SEM showed the thickness of the bacterial cellulose biofilm samples was 5.63 μm, while the 2% v/v thickness of the bacterial cellulose of the extract of mangosteen peel biofilm samples was 12.2 μm. The FTIR results showed a weak interaction between the O-H groups of the microbial cellulose and the C=C functional group in the phenolic compounds of the mangosteen peel extract. Based on the MTT Assay test results using the T47D breast cancer cells, the highest percentage of cell death result was 25.47% on the 2% v/v bacterial cellulose of the mangosteen peel extract samples. The Garcinia mangostana extracts added in the bacterial cellulose biofilms still required optimal concentrations in order to become potential killing mechanism for the T47D breast cancer cells.

EKSTRAK KULIT BUAH MANGGIS (Garcinia Mangostana L.) SEBAGAI OBAT ANTI DIARE

2019 ◽  
Vol 2 (1) ◽  
pp. 9-13
Author(s):  
Zaim Anshari ◽  
Chrismis Novalinda Ginting ◽  
Linda Chiuman ◽  
Yuliani Mardiati Lubis
Keyword(s):  
Blood Vessels ◽  
Smooth Muscles ◽  
Latin Square ◽  
Ethanol Extract ◽  
Garcinia Mangostana ◽  
Pharmacology And Toxicology ◽  
The Difference ◽  
North Sumatra ◽  
Papaverine Hydrochloride

This study aims to determine whether mangosteen rind extract (in the form of ethanol extract/EE) can be used as an anti-diarrhea drug after compared with other anti-diarrhea substances in three experimental groups. This research is an in vitro experimental study using adult male guinea pigs weighing 400-600 gr through the standard method of Magnus with the Latin square controlled experiment design. The study was conducted at the Pharmacology and Toxicology Laboratory of the Faculty of Pharmacy, University of North Sumatra. The results showed that the contraction of ileum in Ach with Atp + Ach compared the difference in contraction of ileum Ach with EE + Ach showed the difference in difference between the two contractions of the ileum was significant, the contraction of ileum in His with Dip + His compared indifference in contraction of ileum His with EE + His showed a difference indifference. the two ileal contractions are significant, the ileal contraction in the bar with Papa + Bar compared to the difference between the ileum bar contraction with EE + Bar shows no difference in the difference between the two ileum contractions. The conclusion is that the Mangosteen Skin Ethanol Extract works similarly to Papaverine Hydrochloride which is an antidiarrheal drug used to relax smooth muscles so that it can also make blood vessels dilate by relaxing smooth muscles in the walls of blood vessels.

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