scholarly journals CANUE: A Theoretical Model of Pain as an Antecedent for Substance Use

2020 ◽  
Author(s):  
Erin Ferguson ◽  
Emily Zale ◽  
Joseph Ditre ◽  
Danielle Wesolowicz ◽  
Bethany Stennett ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Negative Affect ◽  
Pain Catastrophizing ◽  
Outcome Expectancies ◽  
Current Evidence ◽  
Systematic Research ◽  
Negative Urgency ◽  
Pain Coping ◽  
Testable Model

Abstract Background Pain and substance use are frequently comorbid and have been shown to exert bidirectional effects. Self-medication of pain and distress via substance use is common and can be understood via negative reinforcement, ultimately strengthening the pathway between pain to substance use over time. As such, a testable model of the potentially modifiable candidate mechanisms that underlie the pain to substance use pathway is needed. Purpose This review proposes a testable model of pain as an antecedent to substance use to guide future research and inform clinical practice. Methods An integrative review of current evidence regarding pain, substance use, and associated risk factors (i.e., negative affect, pain-related attitudes, negative urgency, and substance use outcome expectancies) was conducted. Results The Catastrophizing, Anxiety, Negative Urgency, and Expectancy (CANUE) model highlights modifiable risk factors for self-medicating pain with substance use, including increased negative affect and maladaptive pain-related attitudes (i.e., pain catastrophizing, pain anxiety, and fear of pain), negative urgency, and substance-related outcome expectancies for pain relief and enhanced pain coping. Conclusions Targeted behavioral and psychological interventions that address these factors may facilitate more adaptive pain-coping responses, thereby reducing the impacts of pain on substance use. Systematic research is needed to evaluate the validity and clinical utility of this model.

scholarly journals A Dynamic Approach to Risk Factors for Maternal Corporal Punishment in Early to Middle Childhood

2017 ◽  
Author(s):  
Michael F Lorber ◽  
Leyco Wilson ◽  
Patti A. Timmons Fritz
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Negative Affect ◽  
Corporal Punishment ◽  
Middle Childhood ◽  
Partner Violence ◽  
Dynamic Approach ◽  
Linear Change ◽  
Intimate Partner Violence Victimization ◽  
Specific Variation

We investigated the utility of a dynamic approach to risk factors for early to middle childhood maternal corporal punishment. Archival data from Fragile Families and Child Wellbeing Study mothers (N = 4,364) were used to model the associations of several risk factors (maternal depression, maternal substance use, parental burden, child negative affect, and intimate partner violence victimization), repeatedly measured at child ages 1 and 3, with both the age 3 level of and age 3-9 linear change in corporal punishment. Unlike most previous research, we distinguished between two types of variation in risk factors, reflecting occasion specific fluctuations as well as their absolute levels. We concentrate herein on the potential role of occasion specific variation in the above risk factors at age 3 – variability that is not a carryover effect from a risk factor’s past level. Mothers who reported perturbations of (i.e., occasion specific variation in) depression, substance use, parenting stress, and child negative affect between ages 1 and 3 reported higher age 3 corporal punishment. Yet age 3 to 9 change in corporal punishment was not successfully predicted. The results underscore the importance of considering occasion specific fluctuations in risk factors, alongside their absolute levels, in the development and prevention of corporal punishment.

scholarly journals A Motivational Perspective on Coping with Pain

2018 ◽  
Author(s):  
Stefaan Van Damme ◽  
Geert Crombez
Keyword(s):  
Problem Solving ◽  
Negative Affect ◽  
Pain Catastrophizing ◽  
Goal Pursuit ◽  
Pain Coping ◽  
Fear Avoidance ◽  
Coping Responses ◽  
Goal Adjustment ◽  
Motivational Model ◽  
Motivational Account

Coping is one of the most commonly used concepts in the pain literature. Despite its popularity, it remains a broad and confusing concept that is often vaguely defined and poorly operationalized. This chapter presents a motivational model of coping that starts from the idea that pain’s interference with goal pursuit elicits negative affect, which in turn activates coping responses that may then proceed along 3 possible pathways: goal persistence, problem-solving, or goal adjustment. The chapter describes and illustrates these pathways and asserts that all three could be either adaptive or maladaptive, depending upon the nature of the context. It recasts several traditional concepts regarding pain coping, such as pain catastrophizing, fear-avoidance, endurance, pain-related attention, and acceptance, within this motivational perspective. It discusses the potential implications of adopting the motivational account of pain coping for clinical interventions such as exposure, attention management, and acceptance, as well as commitment therapy.

Risk factors associated with substance use

2014 ◽  
Author(s):  
Ariel M. Barber ◽  
Alexandra Crouch ◽  
Stephen Campbell
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Factors Associated

Predicting attrition in long-term residential substance use disorder treatment: A modifiable risk factors perspective.

2020 ◽  
Vol 17 (4) ◽  
pp. 472-482
Author(s):  
Danielle E. Baker ◽  
Keith A. Edmonds ◽  
Maegan L. Calvert ◽  
Sarah M. Sanders ◽  
Ana J. Bridges ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Substance Use Disorder ◽  
Modifiable Risk Factors ◽  
Substance Use Disorder Treatment ◽  
Disorder Treatment

Cardiovascular Risk in Rheumatoid Arthritis and Mechanistic Links: From Pathophysiology to Treatment

2020 ◽  
Vol 18 (5) ◽  
pp. 431-446 ◽  
Author(s):  
George E. Fragoulis ◽  
Ismini Panayotidis ◽  
Elena Nikiphorou
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Current Evidence ◽  
Pharmacological Intervention ◽  
Cvd Risk ◽  
The Past ◽  
Increased Risk ◽  
Cv Disease ◽  
Obesity Hypertension ◽  
Inflammatory Burden

Rheumatoid arthritis (RA) is an autoimmune inflammatory arthritis. Inflammation, however, can spread beyond the joints to involve other organs. During the past few years, it has been well recognized that RA associates with increased risk for cardiovascular (CV) disease (CVD) compared with the general population. This seems to be due not only to the increased occurrence in RA of classical CVD risk factors and comorbidities like smoking, obesity, hypertension, diabetes, metabolic syndrome, and others but also to the inflammatory burden that RA itself carries. This is not unexpected given the strong links between inflammation and atherosclerosis and CVD. It has been shown that inflammatory cytokines which are present in abundance in RA play a significant role in every step of plaque formation and rupture. Most of the therapeutic regimes used in RA treatment seem to offer significant benefits to that end. However, more studies are needed to clarify the effect of these drugs on various parameters, including the lipid profile. Of note, although pharmacological intervention significantly helps reduce the inflammatory burden and therefore the CVD risk, control of the so-called classical risk factors is equally important. Herein, we review the current evidence for the underlying pathogenic mechanisms linking inflammation with CVD in the context of RA and reflect on the possible impact of treatments used in RA.

The Role of Different Aspects of Impulsivity as Independent Risk Factors for Substance Use Disorders in Patients with ADHD: A Review

2015 ◽  
Vol 8 (2) ◽  
pp. 119-133 ◽  
Author(s):  
Slobodin Ortal ◽  
van de Glind Geurt ◽  
Franck Johan ◽  
Berger Itai ◽  
Yachin Nir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Substance Use Disorders ◽  
Independent Risk Factors

Socialization processes within adolescents’ relationships with parents and peers predicting couples’ intimate partner violence in adulthood: A social learning perspective

2021 ◽  
pp. 1-14
Author(s):  
Thao Ha ◽  
Mark J. Van Ryzin ◽  
Kit K. Elam
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Partner Violence ◽  
Violent Behavior ◽  
Early Adulthood ◽  
Intimate Partner ◽  
High Risk Sexual Behavior ◽  
Self Reports ◽  
Socialization Processes ◽  
Risk Sexual Behavior

Abstract Previous studies have established that individual characteristics such as violent behavior, substance use, and high-risk sexual behavior, as well as negative relationships with parents and friends, are all risk factors for intimate partner violence (IPV). In this longitudinal prospective study, we investigated whether violent behavior, substance use, and high-risk sexual behavior in early adulthood (ages 22–23 years) mediated the link between family conflict and coercive relationship talk with friends in adolescence (ages 16–17 years) and dyadic IPV in adulthood (ages 28–30 years). A total of 998 individuals participated in multimethod assessments, including observations of interactions with parents and friends. Data from multiple reporters were used for variables of interest including court records, parental and self-reports of violence, self-reports of high-sexual-risk behaviors and substance use, and self- and romantic partner-reports of IPV. Longitudinal mediation analyses showed that violent behavior during early adulthood mediated the link between coercive relationship talk with friends in adolescence and dyadic IPV in adulthood. No other mediation paths were found and there was no evidence of gender differences. Results are discussed with attention to the interpersonal socialization processes by which IPV emerges relative to individual risk factors.

scholarly journals Staphylococcus aureus Keratitis: Incidence, Pathophysiology, Risk Factors and Novel Strategies for Treatment

2021 ◽  
Vol 10 (4) ◽  
pp. 758
Author(s):  
Jason W. Lee ◽  
Tobi Somerville ◽  
Stephen B. Kaye ◽  
Vito Romano
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Clinical Characteristics ◽  
Surgical Intervention ◽  
Current Evidence ◽  
Bacterial Keratitis ◽  
Novel Therapies ◽  
Causative Pathogen ◽  
Novel Treatments

Bacterial keratitis is a devastating condition that can rapidly progress to serious complications if not treated promptly. Certain causative microorganisms such as Staphylococcus aureus and Pseudomonas aeruginosa are notorious for their resistance to antibiotics. Resistant bacterial keratitis results in poorer outcomes such as scarring and the need for surgical intervention. Thorough understanding of the causative pathogen and its virulence factors is vital for the discovery of novel treatments to avoid further antibiotic resistance. While much has been previously reported on P. aeruginosa, S. aureus has been less extensively studied. This review aims to give a brief overview of S. aureus epidemiology, pathophysiology and clinical characteristics as well as summarise the current evidence for potential novel therapies.

610 Self-Reported Sleep and Circadian Characteristics Predict Future Substance Use: A Longitudinal Analysis from the NCANDA Study

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A240-A240
Author(s):  
Brant Hasler ◽  
Jessica Graves ◽  
Meredith Wallace ◽  
Stephanie Claudatos ◽  
Fiona Baker ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Sleep Duration ◽  
Daytime Sleepiness ◽  
Parental Education ◽  
Negative Binomial ◽  
Longitudinal Design ◽  
Random Effect ◽  
Cannabis Use ◽  
Increased Risk

Abstract Introduction Growing evidence indicates that sleep characteristics predict later substance use and related problems during adolescence and young adulthood. However, most prior studies have assessed a limited range of sleep characteristics, studied only a narrow age span, and included relatively few follow-up assessments. Here, we used multiple years of data from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study, which spans the adolescent period with an accelerated longitudinal design, to examine whether multiple sleep characteristics in any year predict substance use the following year. Methods The sample included 831 participants (423 females; age 12–21 years at baseline) from NCANDA. Sleep variables included the previous year’s circadian preference, sleep quality, daytime sleepiness, timing of midsleep (weekday and weekend), and sleep duration (weekday and weekend). Each sleep variable’s association with the subsequent year’s substance use (cannabis use or alcohol binge severity) across years 1–5 was tested separately using generalized linear mixed models (zero-inflated Negative Binomial for cannabis; ordinal for binge severity) with age, sex, race, visit, parental education, previous year’s substance use (yes/no) as covariates and subject as a random effect. Results With regard to cannabis use, greater eveningness and shorter weekday sleep duration predicted an increased risk for additional days of cannabis use the following year, while greater eveningness and later weekend midsleep predicted a greater likelihood of any cannabis use the following year. With regard to alcohol binge severity, greater eveningness, greater daytime sleepiness, and shorter sleep duration (weekday and weekend) all predicted an increased risk for more severe alcohol bingeing the following year. Post-hoc stratified analyses indicated that some of these associations may differ between high school-age and college-age participants. Conclusion Our findings extend prior work, indicating that eveningness and later sleep timing, as well as shorter sleep duration, especially on weekdays, are risk factors for future cannabis use and alcohol misuse. These results underscore a need for greater attention to sleep characteristics as potential risk factors for substance use in adolescents and young adults and may inform future areas of intervention. Support (if any) Grants from NIH: R01AA025626 (Hasler) and U01AA021690 (Clark) and UO1 AA021696 (Baker & Colrain)

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