Intestinal disaccharidases in newborn and mother rats: effect of dietary protein deficiency during pregnancy

1978 ◽  
Vol 31 (6) ◽  
pp. 931-937 ◽  
Author(s):  
M K Younoszai ◽  
J D Swanson ◽  
J Ranshaw
Keyword(s):  
Dietary Protein ◽  
Protein Deficiency ◽  
Intestinal Disaccharidases

scholarly journals Severe protein deficiency induces hepatic expression and systemic level of FGF21 but inhibits its hypothalamic expression in growing rats

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Joanna Moro ◽  
Catherine Chaumontet ◽  
Patrick C. Even ◽  
Anne Blais ◽  
Julien Piedcoq ◽  
...  
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Energy Expenditure ◽  
Energy Intake ◽  
Dietary Protein ◽  
Protein Deficiency ◽  
Protein Diet ◽  
Growing Rats ◽  
Low Protein ◽  
Protein Diets

AbstractTo study, in young growing rats, the consequences of different levels of dietary protein deficiency on food intake, body weight, body composition, and energy balance and to assess the role of FGF21 in the adaptation to a low protein diet. Thirty-six weanling rats were fed diets containing 3%, 5%, 8%, 12%, 15% and 20% protein for three weeks. Body weight, food intake, energy expenditure and metabolic parameters were followed throughout this period. The very low-protein diets (3% and 5%) induced a large decrease in body weight gain and an increase in energy intake relative to body mass. No gain in fat mass was observed because energy expenditure increased in proportion to energy intake. As expected, Fgf21 expression in the liver and plasma FGF21 increased with low-protein diets, but Fgf21 expression in the hypothalamus decreased. Under low protein diets (3% and 5%), the increase in liver Fgf21 and the decrease of Fgf21 in the hypothalamus induced an increase in energy expenditure and the decrease in the satiety signal responsible for hyperphagia. Our results highlight that when dietary protein decreases below 8%, the liver detects the low protein diet and responds by activating synthesis and secretion of FGF21 in order to activate an endocrine signal that induces metabolic adaptation. The hypothalamus, in comparison, responds to protein deficiency when dietary protein decreases below 5%.

Effects of dietary protein deficiency on mineral metabolism and bone mineral density

1992 ◽  
Vol 56 (2) ◽  
pp. 314-319 ◽  
Author(s):  
E Orwoll ◽  
M Ware ◽  
L Stribrska ◽  
D Bikle ◽  
T Sanchez ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Dietary Protein ◽  
Mineral Metabolism ◽  
Protein Deficiency ◽  
Mineral Density

scholarly journals Neurodevelopment and Cognitive Impairment in Parents and Progeny of Perinatal Dietary Protein Deficiency Models

2019 ◽  
Vol 13 ◽  
Author(s):  
Nosarieme O. Abey ◽  
Osaretin A. T. Ebuehi ◽  
Ngozi O. A. Imaga
Keyword(s):  
Cognitive Impairment ◽  
Dietary Protein ◽  
Protein Deficiency

scholarly journals Perinatal dietary protein deficiency perturbs neurodevelopment and cognitive behavior of F1 and F2-generations of rat models

IBRO Reports ◽  
2019 ◽  
Vol 6 ◽  
pp. S77
Author(s):  
Nosarieme Abey ◽  
Osaretin A.T. Ebuehi ◽  
Ngozi. O.A. Imaga
Keyword(s):  
Dietary Protein ◽  
Protein Deficiency ◽  
Cognitive Behavior ◽  
Rat Models

Influence of dietary protein deficiency on lead-copper interaction in rats

1989 ◽  
Vol 18 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Swaran J.S. Flora ◽  
Roger A. Coulombe ◽  
Raghubir P. Sharma ◽  
Sushil K. Tandon
Keyword(s):  
Dietary Protein ◽  
Protein Deficiency

Influence of dietary protein deficiency on phagocytic activity of the reticulo-endothelial cells

1973 ◽  
Vol 109 (3) ◽  
pp. 215-224 ◽  
Author(s):  
M. G. Deo ◽  
Ina Bhan ◽  
V. Ramalingaswami
Keyword(s):  
Endothelial Cells ◽  
Dietary Protein ◽  
Phagocytic Activity ◽  
Protein Deficiency

Influence of dietary protein on the disposition and metabolism of phenylbutazone in rats

1980 ◽  
Vol 58 (3) ◽  
pp. 231-236 ◽  
Author(s):  
Daya R. Varma
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Urinary Excretion ◽  
Dietary Protein ◽  
Area Under The Curve ◽  
Hepatic Metabolism ◽  
Protein Deficiency ◽  
Male Rats ◽  
Low Protein ◽  
Ad Libitum

Influence of dietary protein on the disposition and metabolism of phenylbutazone was investigated in male rats fed ad libitum a 21% (control) or a 5% (low) protein diet for 3 weeks. Phenylbutazone and its metabolites were assayed by high-pressure liquid chromatography. Dietary protein deficiency was associated with a decrease in the conversion of phenylbutazone into oxyphenbutazone by 9000 × g liver supernatant of protein-deficient rats. Also, dietary protein deficiency was associated with a decrease in the urinary excretion of various metabolites of phenylbutazone, namely, oxyphenbutazone γ-hydroxyphenylbutazone, β-hydroxyphenylbutazone, p,γ-dihydroxyphenylbutazone, and an unknown metabolite (not identified). Pretreatment with phenobarbitone or phenylbutazone led to an increase in the hepatic metabolism of phenylbutazone and the urinary excretion of various metabolites in both groups of animals. Within 5 min after an injection of phenylbutazone, plasma contained oxyphenbutazone; the area under the curve of oxyphenbutazone was significantly greater in protein-deficient rats than in controls possibly due to a greater accumulation. It is concluded that dietary protein deficiency is associated with a decrease in the disposition and metabolism of phenylbutazone in rats.

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